Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Todd Pitts

Concepts (373)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
22
2022
621
2.920
Why?
Protein Kinase Inhibitors
19
2020
796
1.990
Why?
Xenograft Model Antitumor Assays
37
2022
706
1.970
Why?
Antineoplastic Agents
25
2020
1897
1.560
Why?
Azepines
4
2020
74
1.410
Why?
Pyrimidines
9
2020
378
1.270
Why?
Pyrazines
6
2018
71
1.080
Why?
Cell Line, Tumor
33
2022
2725
1.030
Why?
Mice, Nude
24
2020
635
1.000
Why?
Cell Proliferation
21
2020
2199
0.880
Why?
Fluorouracil
1
2022
152
0.790
Why?
Triple Negative Breast Neoplasms
6
2020
158
0.780
Why?
Apoptosis
20
2022
2371
0.660
Why?
Camptothecin
5
2022
98
0.660
Why?
Imidazoles
4
2018
211
0.660
Why?
Proto-Oncogene Proteins
5
2018
611
0.650
Why?
Aurora Kinase A
4
2020
52
0.650
Why?
Drug Resistance, Neoplasm
11
2020
642
0.600
Why?
Drug Synergism
4
2014
316
0.580
Why?
Neoplasms
9
2022
2106
0.580
Why?
Cell Cycle Proteins
2
2018
552
0.520
Why?
Cell Cycle Checkpoints
3
2019
85
0.510
Why?
Hydroxamic Acids
3
2011
80
0.500
Why?
Antineoplastic Combined Chemotherapy Protocols
9
2020
1361
0.500
Why?
Tumor Microenvironment
5
2022
434
0.500
Why?
Histone Deacetylase Inhibitors
4
2022
198
0.490
Why?
Mice
38
2022
14935
0.490
Why?
Receptor, IGF Type 1
3
2013
58
0.480
Why?
Pyrazoles
5
2018
364
0.480
Why?
Disease Models, Animal
10
2022
3549
0.470
Why?
Adrenocortical Carcinoma
3
2020
47
0.470
Why?
Mitogen-Activated Protein Kinases
3
2014
278
0.460
Why?
Antimitotic Agents
1
2013
8
0.460
Why?
Benzimidazoles
5
2018
138
0.450
Why?
Pancreatic Neoplasms
5
2020
733
0.430
Why?
TOR Serine-Threonine Kinases
2
2018
359
0.430
Why?
G2 Phase Cell Cycle Checkpoints
4
2022
41
0.430
Why?
Cyclin-Dependent Kinases
1
2013
111
0.420
Why?
Animals
42
2022
31837
0.420
Why?
Boronic Acids
2
2011
33
0.410
Why?
Molecular Targeted Therapy
2
2019
347
0.400
Why?
Quinoxalines
4
2020
60
0.390
Why?
Biomarkers, Tumor
6
2018
1054
0.370
Why?
Colonic Neoplasms
2
2013
222
0.370
Why?
Melanoma
4
2018
631
0.360
Why?
Signal Transduction
17
2019
4524
0.350
Why?
Drug Screening Assays, Antitumor
5
2020
180
0.350
Why?
Heterografts
3
2021
117
0.350
Why?
Oxidoreductases Acting on CH-CH Group Donors
2
2020
20
0.330
Why?
Gene Expression Regulation, Neoplastic
9
2020
1148
0.320
Why?
Wnt Signaling Pathway
4
2020
147
0.310
Why?
Adrenal Cortex Neoplasms
2
2020
48
0.310
Why?
Gene Expression Profiling
6
2016
1523
0.310
Why?
Ephrin-B2
2
2019
36
0.300
Why?
Cell Cycle
7
2018
544
0.300
Why?
Enzyme Inhibitors
5
2020
752
0.300
Why?
Piperazines
2
2020
313
0.300
Why?
Humans
60
2022
114935
0.290
Why?
Programmed Cell Death 1 Receptor
2
2020
195
0.290
Why?
Deoxycytidine
2
2020
138
0.290
Why?
Drug Delivery Systems
1
2010
296
0.290
Why?
Tumor Suppressor Protein p53
4
2016
447
0.290
Why?
Quinazolines
3
2015
243
0.280
Why?
Phosphatidylinositol 3-Kinases
5
2018
330
0.270
Why?
Anilides
2
2018
67
0.270
Why?
Oncogene Proteins, Fusion
2
2018
179
0.270
Why?
Mitogen-Activated Protein Kinase Kinases
3
2019
113
0.260
Why?
Mutation
9
2018
3353
0.260
Why?
Female
38
2020
59580
0.260
Why?
Gene Dosage
4
2015
134
0.250
Why?
Cyclosporine
2
2018
161
0.250
Why?
Lymphocytes, Tumor-Infiltrating
3
2020
114
0.250
Why?
Immunoblotting
6
2015
283
0.240
Why?
Pyrimidinones
2
2015
88
0.240
Why?
Proto-Oncogene Proteins B-raf
3
2018
193
0.240
Why?
Proto-Oncogene Proteins p21(ras)
6
2016
229
0.230
Why?
Pyridones
2
2015
124
0.230
Why?
ras Proteins
4
2013
138
0.230
Why?
Neoplasm Transplantation
4
2018
232
0.220
Why?
Receptor, Notch1
2
2015
61
0.220
Why?
Pyridines
2
2018
425
0.210
Why?
Immunotherapy
3
2022
475
0.210
Why?
Antineoplastic Agents, Immunological
3
2020
152
0.210
Why?
HCT116 Cells
3
2018
71
0.210
Why?
Ataxia Telangiectasia Mutated Proteins
1
2022
63
0.210
Why?
Drug Design
2
2013
151
0.200
Why?
beta Catenin
2
2020
220
0.200
Why?
Gene Knockdown Techniques
4
2020
299
0.190
Why?
DNA-Binding Proteins
2
2020
1317
0.190
Why?
Momordica charantia
1
2020
14
0.180
Why?
Benzoxazoles
1
2020
16
0.180
Why?
HT29 Cells
2
2018
36
0.170
Why?
Neoplasms, Experimental
2
2019
152
0.170
Why?
Immune System
1
2021
173
0.170
Why?
eIF-2 Kinase
1
2019
24
0.170
Why?
src-Family Kinases
2
2017
88
0.170
Why?
Receptor, EphB4
1
2019
23
0.160
Why?
DNA Helicases
1
2020
134
0.160
Why?
Inhibitory Concentration 50
2
2016
75
0.160
Why?
Tumor Burden
2
2018
262
0.160
Why?
Plant Extracts
1
2020
155
0.160
Why?
Breast Neoplasms, Male
1
2018
29
0.160
Why?
Coenzymes
1
2018
16
0.160
Why?
4-Aminobenzoic Acid
1
2018
6
0.150
Why?
Thermodynamics
1
2020
383
0.150
Why?
Neoplasm Invasiveness
3
2020
445
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
68
0.150
Why?
Septins
1
2018
40
0.150
Why?
Adrenal Cortex
1
2018
32
0.150
Why?
Oncogene Proteins v-abl
1
2017
4
0.150
Why?
Carcinoma, Pancreatic Ductal
1
2020
212
0.150
Why?
Dasatinib
1
2017
46
0.150
Why?
Colorectal Neoplasms, Hereditary Nonpolyposis
1
2018
30
0.150
Why?
Neoplasm Proteins
1
2020
385
0.140
Why?
Angiogenesis Inhibitors
3
2018
215
0.140
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2014
86
0.140
Why?
Ubiquitin-Activating Enzymes
1
2016
13
0.140
Why?
Cyclopentanes
1
2016
15
0.140
Why?
Corynebacterium
1
2017
36
0.140
Why?
Tumor Cells, Cultured
4
2020
855
0.140
Why?
Transplantation, Heterologous
4
2022
183
0.140
Why?
Corynebacterium Infections
1
2017
31
0.140
Why?
Insulin-Like Growth Factor I
1
2018
286
0.130
Why?
Tankyrases
1
2016
14
0.130
Why?
Autophagy
1
2018
234
0.130
Why?
Cetuximab
1
2016
91
0.130
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
107
0.130
Why?
Biliary Tract Neoplasms
1
2015
20
0.130
Why?
Capecitabine
1
2015
45
0.130
Why?
Adenocarcinoma
2
2020
801
0.130
Why?
Amyloid Precursor Protein Secretases
2
2013
73
0.130
Why?
Drug Discovery
1
2016
124
0.130
Why?
Genes, ras
2
2018
91
0.130
Why?
Antibodies, Monoclonal, Humanized
1
2020
666
0.130
Why?
Cell Survival
3
2019
1022
0.120
Why?
Diphenylamine
1
2014
6
0.120
Why?
Germ-Line Mutation
2
2018
131
0.120
Why?
DNA Copy Number Variations
1
2015
159
0.120
Why?
Piperidines
1
2015
162
0.120
Why?
Proto-Oncogene Proteins c-met
1
2014
69
0.110
Why?
Benzamides
1
2014
169
0.110
Why?
Urinary Bladder Neoplasms
1
2016
196
0.110
Why?
Protein Kinases
1
2015
307
0.110
Why?
Up-Regulation
1
2016
812
0.110
Why?
Receptor, Insulin
1
2013
93
0.110
Why?
Tetrahydronaphthalenes
1
2013
31
0.110
Why?
Valine
1
2013
72
0.110
Why?
Tumor Suppressor Proteins
1
2015
282
0.100
Why?
Mitosis
1
2013
164
0.100
Why?
Receptors, Notch
1
2013
85
0.100
Why?
Bortezomib
2
2011
41
0.100
Why?
Head and Neck Neoplasms
1
2016
436
0.100
Why?
Middle Aged
12
2020
26806
0.100
Why?
Computational Biology
1
2015
531
0.100
Why?
Sirolimus
1
2013
181
0.100
Why?
Antineoplastic Agents, Phytogenic
1
2013
181
0.100
Why?
3' Untranslated Regions
1
2012
129
0.100
Why?
Carcinoma, Squamous Cell
1
2016
584
0.100
Why?
Benzodioxoles
1
2012
84
0.090
Why?
Proteasome Inhibitors
1
2011
40
0.090
Why?
Aldehyde Dehydrogenase
1
2012
134
0.090
Why?
Nuclear Proteins
1
2015
593
0.090
Why?
Neoplasm Metastasis
3
2018
530
0.090
Why?
Protease Inhibitors
1
2011
99
0.090
Why?
Phosphorylation
4
2019
1572
0.090
Why?
Mice, Inbred NOD
2
2022
561
0.090
Why?
Aged
9
2020
19122
0.090
Why?
Breast Neoplasms
2
2012
1870
0.090
Why?
Vascular Endothelial Growth Factor Receptor-3
1
2009
6
0.090
Why?
Mice, Inbred BALB C
3
2020
1152
0.080
Why?
Vascular Endothelial Growth Factor Receptor-1
1
2009
66
0.080
Why?
Carcinoma, Hepatocellular
1
2011
213
0.080
Why?
Gastrointestinal Neoplasms
1
2009
60
0.080
Why?
Cell Movement
2
2011
867
0.080
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
77
0.080
Why?
Immunosuppressive Agents
1
2013
648
0.080
Why?
Proto-Oncogene Proteins c-akt
3
2018
400
0.080
Why?
Positron-Emission Tomography
3
2018
265
0.080
Why?
Prognosis
4
2019
3344
0.080
Why?
Feasibility Studies
1
2010
737
0.070
Why?
Neutrophils
3
2019
1164
0.070
Why?
Farnesyltranstransferase
1
2007
21
0.070
Why?
Oligonucleotide Array Sequence Analysis
3
2015
744
0.070
Why?
Protein Conformation
2
2020
811
0.070
Why?
Adult
10
2018
30608
0.070
Why?
Reproducibility of Results
2
2010
2770
0.070
Why?
Gene Expression
2
2019
1422
0.070
Why?
Maximum Tolerated Dose
2
2020
184
0.070
Why?
Male
12
2020
55663
0.060
Why?
Quinolones
1
2007
97
0.060
Why?
Neovascularization, Pathologic
2
2018
283
0.060
Why?
Models, Molecular
2
2020
1379
0.060
Why?
Structure-Activity Relationship
2
2018
503
0.060
Why?
Magnetic Resonance Spectroscopy
2
2018
473
0.050
Why?
HMGB1 Protein
1
2003
48
0.050
Why?
Proto-Oncogene Proteins c-raf
1
2002
43
0.050
Why?
Adrenergic alpha-Agonists
1
2002
29
0.050
Why?
Adrenergic alpha-Antagonists
1
2002
30
0.050
Why?
Histones
2
2022
536
0.050
Why?
Neuroimmunomodulation
1
2002
70
0.050
Why?
Histone Deacetylase 1
1
2022
16
0.050
Why?
Aurora Kinases
2
2012
28
0.050
Why?
Genetic Predisposition to Disease
1
2010
2102
0.050
Why?
Adrenergic beta-Agonists
1
2002
126
0.050
Why?
Endotoxemia
1
2002
82
0.050
Why?
Flow Cytometry
2
2019
1087
0.050
Why?
Caspase 3
2
2013
238
0.050
Why?
Acetylation
1
2022
211
0.050
Why?
Chimerism
1
2021
28
0.050
Why?
Campylobacter jejuni
1
2000
11
0.050
Why?
Lymphoid Tissue
1
2021
62
0.050
Why?
Lymphocyte Subsets
1
2021
79
0.050
Why?
Cluster Analysis
2
2012
460
0.050
Why?
Catalase
1
2000
117
0.040
Why?
TCF Transcription Factors
1
2020
20
0.040
Why?
Adrenergic beta-Antagonists
1
2002
288
0.040
Why?
Histone Deacetylases
1
2022
196
0.040
Why?
Mice, SCID
1
2021
320
0.040
Why?
RNA, Neoplasm
1
2020
80
0.040
Why?
Antimetabolites, Antineoplastic
1
2020
82
0.040
Why?
Mechanistic Target of Rapamycin Complex 2
1
2020
55
0.040
Why?
Indolizines
1
2019
3
0.040
Why?
Forkhead Box Protein M1
1
2019
5
0.040
Why?
Mechanistic Target of Rapamycin Complex 1
1
2020
96
0.040
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2019
22
0.040
Why?
Organoids
1
2020
74
0.040
Why?
Small Molecule Libraries
1
2020
80
0.040
Why?
MAP Kinase Kinase 2
2
2013
27
0.040
Why?
Crystallography, X-Ray
1
2020
405
0.040
Why?
MAP Kinase Kinase 1
2
2013
66
0.040
Why?
High-Throughput Screening Assays
1
2020
123
0.040
Why?
Epithelial-Mesenchymal Transition
1
2020
168
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
23
0.040
Why?
Genetic Linkage
1
1999
297
0.040
Why?
Flavin-Adenine Dinucleotide
1
2018
14
0.040
Why?
NADP
1
2018
43
0.040
Why?
Multifactorial Inheritance
1
1999
125
0.040
Why?
Hemorrhage
1
2002
618
0.040
Why?
Radiotherapy
1
2019
176
0.040
Why?
Nausea
1
2018
104
0.040
Why?
Carcinogenesis
1
2019
179
0.040
Why?
Aldosterone
1
2018
42
0.040
Why?
Kaplan-Meier Estimate
1
2020
817
0.040
Why?
DNA Damage
1
2020
357
0.040
Why?
Breast
1
2018
141
0.040
Why?
Drug Therapy, Combination
1
2020
954
0.040
Why?
Area Under Curve
1
2018
275
0.040
Why?
Catalytic Domain
1
2018
197
0.040
Why?
Diarrhea
1
2018
173
0.040
Why?
RNA, Small Interfering
1
2019
543
0.040
Why?
Autistic Disorder
1
1999
162
0.040
Why?
Hypertension
2
2018
1059
0.040
Why?
Recombinant Proteins
1
2020
1233
0.040
Why?
Disease-Free Survival
1
2018
623
0.030
Why?
RNA, Messenger
2
2020
2558
0.030
Why?
Fatigue
1
2018
296
0.030
Why?
Ubiquitination
1
2016
86
0.030
Why?
Axin Protein
1
2016
18
0.030
Why?
Protein Isoforms
1
2017
338
0.030
Why?
T-Lymphocytes, Regulatory
1
2019
343
0.030
Why?
Algorithms
2
2015
1474
0.030
Why?
Sequence Analysis, RNA
1
2018
390
0.030
Why?
Administration, Oral
1
2018
731
0.030
Why?
Hematopoietic Stem Cell Transplantation
1
2021
525
0.030
Why?
Jagged-1 Protein
1
2015
23
0.030
Why?
Serrate-Jagged Proteins
1
2015
28
0.030
Why?
Tumor Protein p73
1
2015
14
0.030
Why?
Gene Duplication
1
2015
63
0.030
Why?
Binding Sites
1
2018
1176
0.030
Why?
Mice, Knockout
1
2021
2586
0.030
Why?
Immunohistochemistry
1
2019
1635
0.030
Why?
Biopsy
1
2018
1045
0.030
Why?
Treatment Outcome
3
2015
9105
0.030
Why?
Databases, Genetic
1
2015
206
0.030
Why?
Transcription, Genetic
1
2020
1317
0.030
Why?
Calcium-Binding Proteins
1
2015
207
0.030
Why?
CD8-Positive T-Lymphocytes
1
2019
692
0.030
Why?
Caspase 7
1
2013
22
0.030
Why?
Butadienes
1
2013
30
0.030
Why?
Intercellular Signaling Peptides and Proteins
1
2015
350
0.030
Why?
Cell Growth Processes
1
2013
51
0.030
Why?
Survival Analysis
1
2016
1220
0.030
Why?
Phenotype
1
2021
2817
0.030
Why?
Tumor Stem Cell Assay
1
2012
33
0.030
Why?
Everolimus
1
2013
61
0.030
Why?
Nitriles
1
2013
151
0.030
Why?
Random Allocation
1
2013
335
0.030
Why?
Neoplasm Staging
1
2015
1180
0.030
Why?
Immunoprecipitation
1
2012
152
0.020
Why?
p38 Mitogen-Activated Protein Kinases
2
2003
262
0.020
Why?
Disease Progression
1
2018
2392
0.020
Why?
Calcium Signaling
1
2013
213
0.020
Why?
Cellular Senescence
1
2012
153
0.020
Why?
Kinetics
1
2014
1555
0.020
Why?
PTEN Phosphohydrolase
1
2012
140
0.020
Why?
In Situ Hybridization, Fluorescence
1
2012
314
0.020
Why?
Enzyme Activation
2
2003
790
0.020
Why?
Proteasome Endopeptidase Complex
1
2011
134
0.020
Why?
Receptor, ErbB-2
1
2012
301
0.020
Why?
Li-Fraumeni Syndrome
1
2010
11
0.020
Why?
Transcriptome
1
2015
728
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
238
0.020
Why?
Neutropenia
1
2010
125
0.020
Why?
Molecular Epidemiology
1
2010
62
0.020
Why?
Metabolome
1
2013
283
0.020
Why?
Population Groups
1
2010
57
0.020
Why?
Ki-67 Antigen
1
2010
106
0.020
Why?
Ligands
1
2011
565
0.020
Why?
Capillary Permeability
1
2010
135
0.020
Why?
Drug Combinations
1
2010
286
0.020
Why?
Australia
1
2010
207
0.020
Why?
Keratinocytes
1
2010
216
0.020
Why?
Membrane Proteins
1
2015
1022
0.020
Why?
Antibodies, Monoclonal
1
2015
1270
0.020
Why?
NF-kappa B
2
2003
637
0.020
Why?
Biomarkers
1
2019
3418
0.020
Why?
Sulfonamides
1
2011
445
0.020
Why?
Calcium
1
2013
1104
0.020
Why?
Magnetic Resonance Imaging
1
2018
3053
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2009
929
0.020
Why?
Enzyme-Linked Immunosorbent Assay
1
2009
797
0.020
Why?
Leukemia-Lymphoma, Adult T-Cell
1
2007
13
0.020
Why?
Verapamil
1
2007
32
0.020
Why?
Liver Neoplasms
1
2011
509
0.020
Why?
Blotting, Western
1
2009
1151
0.020
Why?
Clone Cells
1
2007
248
0.020
Why?
Dose-Response Relationship, Drug
1
2010
1856
0.020
Why?
Calcium Channel Blockers
1
2007
115
0.020
Why?
Metabolomics
1
2011
527
0.020
Why?
Family
1
2010
590
0.020
Why?
Cohort Studies
1
2015
4903
0.020
Why?
MicroRNAs
1
2012
601
0.020
Why?
Ovarian Neoplasms
1
2010
388
0.020
Why?
Adolescent
2
2018
17829
0.010
Why?
Phosphotransferases
1
2003
25
0.010
Why?
Young Adult
1
2018
10478
0.010
Why?
Phentolamine
1
2002
17
0.010
Why?
Ribosomal Protein S6 Kinases
1
2002
21
0.010
Why?
Brimonidine Tartrate
1
2002
9
0.010
Why?
Phenylephrine
1
2002
74
0.010
Why?
Propranolol
1
2002
53
0.010
Why?
Peroxidase
1
2002
157
0.010
Why?
Biological Transport
1
2003
372
0.010
Why?
Mitogen-Activated Protein Kinase 3
1
2002
146
0.010
Why?
Chemokines
1
2003
213
0.010
Why?
Cyclic AMP Response Element-Binding Protein
1
2002
127
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
130
0.010
Why?
omega-N-Methylarginine
1
2000
25
0.010
Why?
Respiratory Burst
1
2000
28
0.010
Why?
MAP Kinase Signaling System
1
2002
276
0.010
Why?
Protein Processing, Post-Translational
1
2002
399
0.010
Why?
Inflammation Mediators
1
2003
476
0.010
Why?
Lipopolysaccharides
1
2003
817
0.010
Why?
Statistical Distributions
1
1999
7
0.010
Why?
Matched-Pair Analysis
1
1999
33
0.010
Why?
Cloning, Molecular
1
2000
524
0.010
Why?
Intelligence Tests
1
1999
59
0.010
Why?
Chromosomes, Human
1
1999
39
0.010
Why?
Nuclear Family
1
1999
49
0.010
Why?
Protein-Tyrosine Kinases
1
2002
399
0.010
Why?
Hydrogen Peroxide
1
2000
287
0.010
Why?
Microsatellite Repeats
1
1999
136
0.010
Why?
Linkage Disequilibrium
1
1999
245
0.010
Why?
Models, Genetic
1
1999
565
0.010
Why?
Cells, Cultured
1
2003
3897
0.010
Why?
Cytokines
1
2003
1843
0.010
Why?
Cell Line
1
2000
2640
0.010
Why?
Molecular Sequence Data
1
1999
2791
0.010
Why?
Genotype
1
1999
1775
0.010
Why?
Sex Factors
1
1999
1721
0.010
Why?
Macrophages
1
2000
1266
0.010
Why?
Child, Preschool
1
1999
9086
0.000
Why?
Child
1
1999
18366
0.000
Why?
Pitts's Networks
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