Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Todd Pitts

Concepts (373)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
22
2022
592
2.920
Why?
Protein Kinase Inhibitors
19
2020
779
1.970
Why?
Xenograft Model Antitumor Assays
37
2022
693
1.940
Why?
Antineoplastic Agents
25
2020
1872
1.540
Why?
Azepines
4
2020
69
1.380
Why?
Pyrimidines
9
2020
372
1.250
Why?
Pyrazines
6
2018
70
1.060
Why?
Cell Line, Tumor
33
2022
2690
1.020
Why?
Mice, Nude
24
2020
625
0.990
Why?
Cell Proliferation
21
2020
2164
0.870
Why?
Fluorouracil
1
2022
151
0.770
Why?
Triple Negative Breast Neoplasms
6
2020
157
0.760
Why?
Apoptosis
20
2022
2288
0.660
Why?
Camptothecin
5
2022
95
0.650
Why?
Proto-Oncogene Proteins
5
2018
595
0.640
Why?
Imidazoles
4
2018
203
0.640
Why?
Aurora Kinase A
4
2020
51
0.640
Why?
Drug Resistance, Neoplasm
11
2020
636
0.590
Why?
Drug Synergism
4
2014
312
0.570
Why?
Neoplasms
9
2022
2082
0.570
Why?
Cell Cycle Proteins
2
2018
543
0.510
Why?
Cell Cycle Checkpoints
3
2019
85
0.500
Why?
Hydroxamic Acids
3
2011
80
0.490
Why?
Antineoplastic Combined Chemotherapy Protocols
9
2020
1356
0.490
Why?
Tumor Microenvironment
5
2022
428
0.490
Why?
Mice
38
2022
14679
0.490
Why?
Histone Deacetylase Inhibitors
4
2022
197
0.480
Why?
Receptor, IGF Type 1
3
2013
58
0.470
Why?
Disease Models, Animal
10
2022
3470
0.470
Why?
Pyrazoles
5
2018
361
0.470
Why?
Adrenocortical Carcinoma
3
2020
47
0.460
Why?
Mitogen-Activated Protein Kinases
3
2014
262
0.450
Why?
Antimitotic Agents
1
2013
8
0.450
Why?
Benzimidazoles
5
2018
137
0.440
Why?
Pancreatic Neoplasms
5
2020
721
0.430
Why?
TOR Serine-Threonine Kinases
2
2018
357
0.420
Why?
G2 Phase Cell Cycle Checkpoints
4
2022
41
0.420
Why?
Animals
42
2022
31162
0.420
Why?
Cyclin-Dependent Kinases
1
2013
110
0.420
Why?
Boronic Acids
2
2011
33
0.400
Why?
Molecular Targeted Therapy
2
2019
345
0.400
Why?
Quinoxalines
4
2020
60
0.380
Why?
Biomarkers, Tumor
6
2018
1029
0.360
Why?
Colonic Neoplasms
2
2013
210
0.360
Why?
Melanoma
4
2018
620
0.360
Why?
Signal Transduction
17
2019
4439
0.350
Why?
Drug Screening Assays, Antitumor
5
2020
181
0.350
Why?
Heterografts
3
2021
117
0.340
Why?
Oxidoreductases Acting on CH-CH Group Donors
2
2020
20
0.330
Why?
Gene Expression Regulation, Neoplastic
9
2020
1140
0.320
Why?
Wnt Signaling Pathway
4
2020
145
0.310
Why?
Gene Expression Profiling
6
2016
1510
0.300
Why?
Adrenal Cortex Neoplasms
2
2020
46
0.300
Why?
Cell Cycle
7
2018
538
0.300
Why?
Ephrin-B2
2
2019
34
0.290
Why?
Enzyme Inhibitors
5
2020
737
0.290
Why?
Humans
60
2022
113531
0.290
Why?
Piperazines
2
2020
309
0.290
Why?
Programmed Cell Death 1 Receptor
2
2020
193
0.290
Why?
Drug Delivery Systems
1
2010
293
0.280
Why?
Deoxycytidine
2
2020
137
0.280
Why?
Tumor Suppressor Protein p53
4
2016
443
0.280
Why?
Quinazolines
3
2015
239
0.270
Why?
Phosphatidylinositol 3-Kinases
5
2018
324
0.270
Why?
Oncogene Proteins, Fusion
2
2018
178
0.260
Why?
Anilides
2
2018
67
0.260
Why?
Mutation
9
2018
3313
0.260
Why?
Female
38
2020
59115
0.260
Why?
Mitogen-Activated Protein Kinase Kinases
3
2019
112
0.260
Why?
Gene Dosage
4
2015
129
0.250
Why?
Cyclosporine
2
2018
160
0.250
Why?
Lymphocytes, Tumor-Infiltrating
3
2020
111
0.250
Why?
Immunoblotting
6
2015
277
0.240
Why?
Pyrimidinones
2
2015
88
0.230
Why?
Proto-Oncogene Proteins B-raf
3
2018
191
0.230
Why?
Proto-Oncogene Proteins p21(ras)
6
2016
227
0.230
Why?
Pyridones
2
2015
122
0.230
Why?
ras Proteins
4
2013
136
0.220
Why?
Neoplasm Transplantation
4
2018
227
0.220
Why?
Receptor, Notch1
2
2015
59
0.220
Why?
Pyridines
2
2018
417
0.210
Why?
Immunotherapy
3
2022
472
0.210
Why?
Antineoplastic Agents, Immunological
3
2020
152
0.210
Why?
HCT116 Cells
3
2018
70
0.200
Why?
Ataxia Telangiectasia Mutated Proteins
1
2022
62
0.200
Why?
Drug Design
2
2013
146
0.200
Why?
beta Catenin
2
2020
208
0.190
Why?
DNA-Binding Proteins
2
2020
1286
0.180
Why?
Gene Knockdown Techniques
4
2020
298
0.180
Why?
Momordica charantia
1
2020
13
0.180
Why?
Benzoxazoles
1
2020
16
0.170
Why?
HT29 Cells
2
2018
35
0.170
Why?
Neoplasms, Experimental
2
2019
149
0.170
Why?
Immune System
1
2021
167
0.170
Why?
eIF-2 Kinase
1
2019
24
0.160
Why?
src-Family Kinases
2
2017
84
0.160
Why?
Receptor, EphB4
1
2019
22
0.160
Why?
DNA Helicases
1
2020
133
0.160
Why?
Tumor Burden
2
2018
257
0.160
Why?
Inhibitory Concentration 50
2
2016
74
0.160
Why?
Plant Extracts
1
2020
154
0.150
Why?
Breast Neoplasms, Male
1
2018
28
0.150
Why?
Coenzymes
1
2018
15
0.150
Why?
4-Aminobenzoic Acid
1
2018
6
0.150
Why?
Thermodynamics
1
2020
378
0.150
Why?
Neoplasm Invasiveness
3
2020
435
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
67
0.150
Why?
Septins
1
2018
40
0.150
Why?
Adrenal Cortex
1
2018
26
0.150
Why?
Carcinoma, Pancreatic Ductal
1
2020
209
0.150
Why?
Oncogene Proteins v-abl
1
2017
4
0.150
Why?
Dasatinib
1
2017
43
0.140
Why?
Colorectal Neoplasms, Hereditary Nonpolyposis
1
2018
30
0.140
Why?
Neoplasm Proteins
1
2020
381
0.140
Why?
Angiogenesis Inhibitors
3
2018
212
0.140
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2014
85
0.140
Why?
Cyclopentanes
1
2016
13
0.140
Why?
Ubiquitin-Activating Enzymes
1
2016
13
0.140
Why?
Tumor Cells, Cultured
4
2020
834
0.130
Why?
Corynebacterium
1
2017
35
0.130
Why?
Transplantation, Heterologous
4
2022
180
0.130
Why?
Corynebacterium Infections
1
2017
31
0.130
Why?
Insulin-Like Growth Factor I
1
2018
280
0.130
Why?
Tankyrases
1
2016
12
0.130
Why?
Autophagy
1
2018
235
0.130
Why?
Cetuximab
1
2016
89
0.130
Why?
Adenocarcinoma
2
2020
787
0.130
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
107
0.130
Why?
Biliary Tract Neoplasms
1
2015
20
0.130
Why?
Capecitabine
1
2015
45
0.130
Why?
Amyloid Precursor Protein Secretases
2
2013
72
0.130
Why?
Drug Discovery
1
2016
122
0.130
Why?
Antibodies, Monoclonal, Humanized
1
2020
654
0.120
Why?
Cell Survival
3
2019
1004
0.120
Why?
Genes, ras
2
2018
91
0.120
Why?
Diphenylamine
1
2014
6
0.120
Why?
DNA Copy Number Variations
1
2015
153
0.120
Why?
Germ-Line Mutation
2
2018
131
0.120
Why?
Piperidines
1
2015
159
0.120
Why?
Proto-Oncogene Proteins c-met
1
2014
67
0.110
Why?
Urinary Bladder Neoplasms
1
2016
196
0.110
Why?
Benzamides
1
2014
168
0.110
Why?
Protein Kinases
1
2015
300
0.110
Why?
Up-Regulation
1
2016
794
0.110
Why?
Receptor, Insulin
1
2013
93
0.110
Why?
Tetrahydronaphthalenes
1
2013
29
0.110
Why?
Valine
1
2013
72
0.100
Why?
Tumor Suppressor Proteins
1
2015
283
0.100
Why?
Mitosis
1
2013
161
0.100
Why?
Receptors, Notch
1
2013
83
0.100
Why?
Bortezomib
2
2011
41
0.100
Why?
Head and Neck Neoplasms
1
2016
423
0.100
Why?
Middle Aged
12
2020
26552
0.100
Why?
Computational Biology
1
2015
527
0.100
Why?
Sirolimus
1
2013
181
0.100
Why?
Antineoplastic Agents, Phytogenic
1
2013
180
0.100
Why?
3' Untranslated Regions
1
2012
129
0.090
Why?
Carcinoma, Squamous Cell
1
2016
575
0.090
Why?
Benzodioxoles
1
2012
83
0.090
Why?
Aldehyde Dehydrogenase
1
2012
102
0.090
Why?
Proteasome Inhibitors
1
2011
41
0.090
Why?
Nuclear Proteins
1
2015
584
0.090
Why?
Neoplasm Metastasis
3
2018
519
0.090
Why?
Phosphorylation
4
2019
1537
0.090
Why?
Protease Inhibitors
1
2011
96
0.090
Why?
Aged
9
2020
18944
0.090
Why?
Breast Neoplasms
2
2012
1842
0.090
Why?
Mice, Inbred NOD
2
2022
551
0.090
Why?
Vascular Endothelial Growth Factor Receptor-3
1
2009
6
0.080
Why?
Mice, Inbred BALB C
3
2020
1136
0.080
Why?
Carcinoma, Hepatocellular
1
2011
210
0.080
Why?
Vascular Endothelial Growth Factor Receptor-1
1
2009
67
0.080
Why?
Cell Movement
2
2011
852
0.080
Why?
Gastrointestinal Neoplasms
1
2009
59
0.080
Why?
Immunosuppressive Agents
1
2013
633
0.080
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
76
0.080
Why?
Proto-Oncogene Proteins c-akt
3
2018
394
0.080
Why?
Positron-Emission Tomography
3
2018
260
0.080
Why?
Prognosis
4
2019
3318
0.070
Why?
Neutrophils
3
2019
1072
0.070
Why?
Feasibility Studies
1
2010
737
0.070
Why?
Farnesyltranstransferase
1
2007
21
0.070
Why?
Oligonucleotide Array Sequence Analysis
3
2015
739
0.070
Why?
Protein Conformation
2
2020
798
0.070
Why?
Adult
10
2018
30245
0.070
Why?
Reproducibility of Results
2
2010
2752
0.070
Why?
Gene Expression
2
2019
1397
0.060
Why?
Maximum Tolerated Dose
2
2020
182
0.060
Why?
Male
12
2020
55112
0.060
Why?
Quinolones
1
2007
97
0.060
Why?
Neovascularization, Pathologic
2
2018
280
0.060
Why?
Models, Molecular
2
2020
1359
0.060
Why?
Structure-Activity Relationship
2
2018
497
0.060
Why?
Magnetic Resonance Spectroscopy
2
2018
472
0.050
Why?
HMGB1 Protein
1
2003
47
0.050
Why?
Proto-Oncogene Proteins c-raf
1
2002
43
0.050
Why?
Adrenergic alpha-Agonists
1
2002
29
0.050
Why?
Histones
2
2022
528
0.050
Why?
Adrenergic alpha-Antagonists
1
2002
29
0.050
Why?
Neuroimmunomodulation
1
2002
65
0.050
Why?
Histone Deacetylase 1
1
2022
16
0.050
Why?
Genetic Predisposition to Disease
1
2010
2077
0.050
Why?
Aurora Kinases
2
2012
28
0.050
Why?
Adrenergic beta-Agonists
1
2002
125
0.050
Why?
Endotoxemia
1
2002
86
0.050
Why?
Flow Cytometry
2
2019
1065
0.050
Why?
Caspase 3
2
2013
227
0.050
Why?
Acetylation
1
2022
208
0.050
Why?
Chimerism
1
2021
28
0.050
Why?
Campylobacter jejuni
1
2000
11
0.050
Why?
Lymphoid Tissue
1
2021
62
0.050
Why?
Lymphocyte Subsets
1
2021
79
0.040
Why?
Cluster Analysis
2
2012
448
0.040
Why?
Catalase
1
2000
118
0.040
Why?
TCF Transcription Factors
1
2020
16
0.040
Why?
Adrenergic beta-Antagonists
1
2002
286
0.040
Why?
Histone Deacetylases
1
2022
194
0.040
Why?
Mice, SCID
1
2021
311
0.040
Why?
Antimetabolites, Antineoplastic
1
2020
80
0.040
Why?
RNA, Neoplasm
1
2020
81
0.040
Why?
Mechanistic Target of Rapamycin Complex 2
1
2020
55
0.040
Why?
Indolizines
1
2019
3
0.040
Why?
Forkhead Box Protein M1
1
2019
5
0.040
Why?
Mechanistic Target of Rapamycin Complex 1
1
2020
97
0.040
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2019
22
0.040
Why?
Organoids
1
2020
74
0.040
Why?
Small Molecule Libraries
1
2020
79
0.040
Why?
MAP Kinase Kinase 2
2
2013
27
0.040
Why?
Crystallography, X-Ray
1
2020
402
0.040
Why?
MAP Kinase Kinase 1
2
2013
66
0.040
Why?
High-Throughput Screening Assays
1
2020
123
0.040
Why?
Epithelial-Mesenchymal Transition
1
2020
166
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
23
0.040
Why?
Genetic Linkage
1
1999
289
0.040
Why?
Flavin-Adenine Dinucleotide
1
2018
14
0.040
Why?
Multifactorial Inheritance
1
1999
120
0.040
Why?
Hemorrhage
1
2002
599
0.040
Why?
NADP
1
2018
42
0.040
Why?
Carcinogenesis
1
2019
172
0.040
Why?
Radiotherapy
1
2019
173
0.040
Why?
Nausea
1
2018
96
0.040
Why?
DNA Damage
1
2020
345
0.040
Why?
Aldosterone
1
2018
40
0.040
Why?
Kaplan-Meier Estimate
1
2020
809
0.040
Why?
Drug Therapy, Combination
1
2020
944
0.040
Why?
Breast
1
2018
138
0.040
Why?
Area Under Curve
1
2018
271
0.040
Why?
Catalytic Domain
1
2018
193
0.040
Why?
RNA, Small Interfering
1
2019
528
0.040
Why?
Diarrhea
1
2018
170
0.040
Why?
Autistic Disorder
1
1999
160
0.030
Why?
Hypertension
2
2018
1051
0.030
Why?
Recombinant Proteins
1
2020
1214
0.030
Why?
RNA, Messenger
2
2020
2507
0.030
Why?
Disease-Free Survival
1
2018
617
0.030
Why?
Fatigue
1
2018
292
0.030
Why?
Ubiquitination
1
2016
86
0.030
Why?
Protein Isoforms
1
2017
324
0.030
Why?
Axin Protein
1
2016
16
0.030
Why?
T-Lymphocytes, Regulatory
1
2019
337
0.030
Why?
Algorithms
2
2015
1462
0.030
Why?
Sequence Analysis, RNA
1
2018
387
0.030
Why?
Administration, Oral
1
2018
719
0.030
Why?
Hematopoietic Stem Cell Transplantation
1
2021
512
0.030
Why?
Jagged-1 Protein
1
2015
22
0.030
Why?
Serrate-Jagged Proteins
1
2015
27
0.030
Why?
Tumor Protein p73
1
2015
14
0.030
Why?
Gene Duplication
1
2015
61
0.030
Why?
Binding Sites
1
2018
1153
0.030
Why?
Mice, Knockout
1
2021
2523
0.030
Why?
Immunohistochemistry
1
2019
1604
0.030
Why?
Treatment Outcome
3
2015
9006
0.030
Why?
Biopsy
1
2018
1024
0.030
Why?
Databases, Genetic
1
2015
205
0.030
Why?
Transcription, Genetic
1
2020
1282
0.030
Why?
Calcium-Binding Proteins
1
2015
201
0.030
Why?
CD8-Positive T-Lymphocytes
1
2019
686
0.030
Why?
Caspase 7
1
2013
20
0.030
Why?
Butadienes
1
2013
30
0.030
Why?
Intercellular Signaling Peptides and Proteins
1
2015
344
0.030
Why?
Cell Growth Processes
1
2013
51
0.030
Why?
Survival Analysis
1
2016
1203
0.030
Why?
Phenotype
1
2021
2754
0.030
Why?
Tumor Stem Cell Assay
1
2012
33
0.030
Why?
Nitriles
1
2013
149
0.030
Why?
Everolimus
1
2013
61
0.030
Why?
Random Allocation
1
2013
326
0.030
Why?
Neoplasm Staging
1
2015
1159
0.020
Why?
p38 Mitogen-Activated Protein Kinases
2
2003
244
0.020
Why?
Immunoprecipitation
1
2012
150
0.020
Why?
Disease Progression
1
2018
2364
0.020
Why?
Cellular Senescence
1
2012
150
0.020
Why?
Calcium Signaling
1
2013
210
0.020
Why?
Kinetics
1
2014
1528
0.020
Why?
PTEN Phosphohydrolase
1
2012
140
0.020
Why?
Enzyme Activation
2
2003
752
0.020
Why?
In Situ Hybridization, Fluorescence
1
2012
306
0.020
Why?
Proteasome Endopeptidase Complex
1
2011
132
0.020
Why?
Receptor, ErbB-2
1
2012
299
0.020
Why?
Li-Fraumeni Syndrome
1
2010
11
0.020
Why?
Transcriptome
1
2015
719
0.020
Why?
Metabolome
1
2013
275
0.020
Why?
Neutropenia
1
2010
122
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
237
0.020
Why?
Molecular Epidemiology
1
2010
62
0.020
Why?
Population Groups
1
2010
55
0.020
Why?
Ligands
1
2011
553
0.020
Why?
Ki-67 Antigen
1
2010
101
0.020
Why?
Drug Combinations
1
2010
285
0.020
Why?
Capillary Permeability
1
2010
134
0.020
Why?
Australia
1
2010
205
0.020
Why?
Membrane Proteins
1
2015
1008
0.020
Why?
Keratinocytes
1
2010
215
0.020
Why?
Antibodies, Monoclonal
1
2015
1236
0.020
Why?
NF-kappa B
2
2003
615
0.020
Why?
Biomarkers
1
2019
3389
0.020
Why?
Sulfonamides
1
2011
442
0.020
Why?
Calcium
1
2013
1086
0.020
Why?
Magnetic Resonance Imaging
1
2018
3013
0.020
Why?
Enzyme-Linked Immunosorbent Assay
1
2009
783
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2009
914
0.020
Why?
Leukemia-Lymphoma, Adult T-Cell
1
2007
12
0.020
Why?
Liver Neoplasms
1
2011
504
0.020
Why?
Verapamil
1
2007
32
0.020
Why?
Blotting, Western
1
2009
1128
0.020
Why?
Dose-Response Relationship, Drug
1
2010
1822
0.020
Why?
Clone Cells
1
2007
245
0.020
Why?
Calcium Channel Blockers
1
2007
112
0.020
Why?
Metabolomics
1
2011
508
0.020
Why?
Family
1
2010
588
0.020
Why?
Cohort Studies
1
2015
4880
0.020
Why?
MicroRNAs
1
2012
598
0.020
Why?
Ovarian Neoplasms
1
2010
386
0.020
Why?
Adolescent
2
2018
17724
0.010
Why?
Young Adult
1
2018
10400
0.010
Why?
Phosphotransferases
1
2003
25
0.010
Why?
Phentolamine
1
2002
13
0.010
Why?
Ribosomal Protein S6 Kinases
1
2002
21
0.010
Why?
Brimonidine Tartrate
1
2002
9
0.010
Why?
Phenylephrine
1
2002
71
0.010
Why?
Propranolol
1
2002
46
0.010
Why?
Peroxidase
1
2002
160
0.010
Why?
Biological Transport
1
2003
363
0.010
Why?
Chemokines
1
2003
214
0.010
Why?
Mitogen-Activated Protein Kinase 3
1
2002
144
0.010
Why?
Cyclic AMP Response Element-Binding Protein
1
2002
126
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
128
0.010
Why?
Respiratory Burst
1
2000
16
0.010
Why?
omega-N-Methylarginine
1
2000
26
0.010
Why?
MAP Kinase Signaling System
1
2002
267
0.010
Why?
Protein Processing, Post-Translational
1
2002
394
0.010
Why?
Inflammation Mediators
1
2003
469
0.010
Why?
Lipopolysaccharides
1
2003
802
0.010
Why?
Statistical Distributions
1
1999
7
0.010
Why?
Matched-Pair Analysis
1
1999
35
0.010
Why?
Cloning, Molecular
1
2000
514
0.010
Why?
Intelligence Tests
1
1999
56
0.010
Why?
Chromosomes, Human
1
1999
38
0.010
Why?
Nuclear Family
1
1999
47
0.010
Why?
Protein-Tyrosine Kinases
1
2002
390
0.010
Why?
Hydrogen Peroxide
1
2000
287
0.010
Why?
Microsatellite Repeats
1
1999
132
0.010
Why?
Linkage Disequilibrium
1
1999
239
0.010
Why?
Models, Genetic
1
1999
542
0.010
Why?
Cells, Cultured
1
2003
3802
0.010
Why?
Cytokines
1
2003
1795
0.010
Why?
Cell Line
1
2000
2581
0.010
Why?
Molecular Sequence Data
1
1999
2741
0.010
Why?
Genotype
1
1999
1733
0.010
Why?
Sex Factors
1
1999
1705
0.010
Why?
Macrophages
1
2000
1233
0.010
Why?
Child, Preschool
1
1999
9093
0.000
Why?
Child
1
1999
18340
0.000
Why?
Pitts's Networks
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