Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christina Coughlan

Concepts (338)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Alzheimer Disease
9
2025
570
2.140
Why?
Extracellular Vesicles
7
2025
148
1.760
Why?
Exosomes
3
2023
105
0.830
Why?
Astrocytes
4
2022
215
0.810
Why?
White Matter
2
2023
144
0.770
Why?
Gliosis
2
2023
28
0.740
Why?
Proteasome Endopeptidase Complex
2
2022
159
0.740
Why?
Sialyltransferases
8
1999
13
0.720
Why?
Amyloid beta-Protein Precursor
5
2022
68
0.690
Why?
Healthy Aging
1
2021
35
0.670
Why?
Glial Fibrillary Acidic Protein
1
2021
102
0.670
Why?
Ultracentrifugation
1
2020
52
0.670
Why?
Memory, Episodic
1
2021
50
0.670
Why?
Saccharomyces cerevisiae
5
2022
552
0.560
Why?
Amyloid beta-Peptides
5
2022
227
0.510
Why?
Proteomics
3
2024
1113
0.480
Why?
Peptide Fragments
3
2022
691
0.470
Why?
Cognitive Dysfunction
3
2025
390
0.450
Why?
Nanoparticles
1
2020
468
0.450
Why?
Dexamethasone
7
1999
375
0.400
Why?
Brain Ischemia
2
2025
343
0.330
Why?
Neurons
6
2022
1603
0.330
Why?
Herpes Zoster
3
2024
314
0.330
Why?
Down Syndrome
4
2022
486
0.330
Why?
Islet Amyloid Polypeptide
2
2021
47
0.330
Why?
Sialoglycoproteins
3
1997
159
0.280
Why?
Protein Folding
3
2005
279
0.280
Why?
Neuroblastoma
3
1999
160
0.240
Why?
Herpesvirus 3, Human
3
2024
331
0.240
Why?
Stroke
3
2023
1137
0.240
Why?
Proteome
2
2024
471
0.240
Why?
Plasma
2
2024
221
0.230
Why?
Sodium Bicarbonate
1
2025
46
0.230
Why?
Tetraspanin 28
1
2024
6
0.220
Why?
Protein Conformation
2
2005
944
0.220
Why?
Chordoma
1
2024
14
0.220
Why?
DNA Transposable Elements
1
2025
122
0.220
Why?
Idiopathic Pulmonary Fibrosis
2
2024
658
0.220
Why?
alpha-Synuclein
1
2024
41
0.220
Why?
Mitochondria
2
2025
958
0.220
Why?
Acidosis
1
2025
104
0.220
Why?
Amyloidogenic Proteins
1
2024
16
0.220
Why?
Aprotinin
1
2004
9
0.220
Why?
Varicella Zoster Virus Infection
2
2024
24
0.210
Why?
Vacuoles
1
2004
40
0.210
Why?
Osteoblasts
1
2024
131
0.210
Why?
Glucocorticoids
3
1999
531
0.210
Why?
Tumor Microenvironment
2
2024
668
0.210
Why?
Interleukin-6
2
2025
786
0.210
Why?
Recombinant Proteins
2
2007
1358
0.210
Why?
Neurodegenerative Diseases
1
2005
138
0.200
Why?
Humans
35
2025
138651
0.200
Why?
Bleomycin
1
2024
249
0.200
Why?
Cerebrovascular Circulation
1
2025
266
0.200
Why?
Epithelial-Mesenchymal Transition
1
2024
211
0.200
Why?
Colon
1
2025
287
0.190
Why?
Aged, 80 and over
7
2025
7683
0.190
Why?
Diabetic Neuropathies
1
2023
93
0.190
Why?
Cognition
3
2025
1176
0.190
Why?
Ischemic Attack, Transient
1
2023
67
0.190
Why?
Apolipoprotein E4
1
2022
37
0.190
Why?
Protein Processing, Post-Translational
4
2011
463
0.180
Why?
Disease
1
2003
100
0.180
Why?
Fatty Acids
1
2025
446
0.180
Why?
Animals
22
2025
37309
0.180
Why?
Bronchoalveolar Lavage Fluid
1
2024
648
0.180
Why?
Retinal Drusen
1
2021
31
0.180
Why?
Endoplasmic Reticulum
1
2004
270
0.180
Why?
Peptides
2
2024
984
0.180
Why?
Virion
1
2022
113
0.170
Why?
Retinal Pigment Epithelium
1
2021
76
0.170
Why?
Aldosterone
4
1999
42
0.170
Why?
Arteritis
1
2021
27
0.170
Why?
Biomarkers
6
2025
4111
0.170
Why?
Central Nervous System Viral Diseases
1
2022
76
0.170
Why?
Chemical Precipitation
1
2020
38
0.170
Why?
Brain-Derived Neurotrophic Factor
1
2021
140
0.170
Why?
Cell Polarity
1
2021
140
0.170
Why?
Epigenesis, Genetic
1
2025
647
0.170
Why?
Myelitis
1
2022
104
0.170
Why?
Stem Cells
1
2025
598
0.170
Why?
Adipose Tissue
1
2025
643
0.170
Why?
Enterovirus D, Human
1
2022
85
0.160
Why?
Amyloid
1
2021
94
0.160
Why?
Cell Movement
1
2024
972
0.160
Why?
Neuromuscular Diseases
1
2022
129
0.160
Why?
Receptors, Chemokine
1
2000
49
0.160
Why?
Macular Degeneration
1
2021
166
0.160
Why?
Chemokine CCL2
1
2000
116
0.160
Why?
Aged
11
2025
24182
0.160
Why?
Adrenal Cortex Hormones
3
1999
496
0.150
Why?
Enterovirus Infections
1
2022
173
0.150
Why?
Fibroblasts
1
2024
1002
0.150
Why?
Wnt-5a Protein
1
2018
24
0.150
Why?
Signal Transduction
4
2021
5091
0.150
Why?
Renal Insufficiency, Chronic
1
2025
621
0.150
Why?
Frontotemporal Lobar Degeneration
1
2017
18
0.140
Why?
Cell Communication
2
2000
316
0.140
Why?
Kidney
2
2015
1480
0.140
Why?
N-Acetylneuraminic Acid
2
1999
11
0.140
Why?
Proteostasis Deficiencies
1
2017
5
0.130
Why?
Melanoma
1
2024
766
0.130
Why?
Aneuploidy
1
2017
88
0.130
Why?
tau Proteins
1
2017
95
0.130
Why?
Tumor Cells, Cultured
5
2000
949
0.130
Why?
Trisomy
1
2017
75
0.130
Why?
Brain Chemistry
1
1996
115
0.120
Why?
Carcinoma, Hepatocellular
2
1997
359
0.120
Why?
Proteins
1
2021
1014
0.120
Why?
Isoenzymes
1
1996
304
0.120
Why?
Aging
2
2025
1859
0.120
Why?
Models, Biological
1
2003
1815
0.120
Why?
Cystic Fibrosis
1
2005
1106
0.120
Why?
Male
13
2025
68216
0.110
Why?
Brain
4
2023
2782
0.110
Why?
Molecular Sequence Data
5
2015
2928
0.110
Why?
Oxidative Stress
2
2021
1326
0.100
Why?
Middle Aged
8
2025
33792
0.100
Why?
Mitochondrial Proteins
1
2015
258
0.100
Why?
Female
12
2025
73913
0.100
Why?
Membrane Proteins
3
2024
1153
0.100
Why?
Enzyme Induction
3
1997
90
0.090
Why?
Nerve Tissue Proteins
1
1996
602
0.090
Why?
Obesity
1
2025
2994
0.090
Why?
Transcription Factor AP-2
1
2011
82
0.090
Why?
Amino Acid Sequence
3
2015
2162
0.090
Why?
Parkinson Disease
1
2017
546
0.090
Why?
Glioma
1
1995
403
0.090
Why?
Mice
9
2025
17848
0.090
Why?
Ethanol
1
2015
618
0.080
Why?
Rats
7
1999
5594
0.080
Why?
Mice, Inbred C57BL
4
2025
5812
0.080
Why?
Membrane Transport Proteins
1
2011
153
0.080
Why?
Adrenalectomy
4
1999
65
0.080
Why?
Apoptosis
2
2017
2558
0.080
Why?
Palliative Care
1
2017
814
0.080
Why?
Cells, Cultured
4
2021
4175
0.080
Why?
Cell Line, Tumor
3
2024
3406
0.080
Why?
Disease Models, Animal
3
2025
4333
0.080
Why?
Caregivers
1
2017
904
0.080
Why?
Attitude of Health Personnel
1
2017
1157
0.080
Why?
Diabetes Mellitus, Type 2
1
2023
2513
0.070
Why?
Receptors, Nicotinic
1
2011
345
0.070
Why?
Alcoholism
1
2015
820
0.070
Why?
Glycosylation
3
1999
162
0.070
Why?
Saccharomyces cerevisiae Proteins
1
2011
401
0.070
Why?
Schizophrenia
1
2011
451
0.070
Why?
Liver
1
1996
1876
0.070
Why?
Drug Stability
1
2007
163
0.070
Why?
DNA Primers
1
2007
509
0.060
Why?
Adult
4
2024
38296
0.060
Why?
Golgi Apparatus
2
2004
100
0.060
Why?
Polysaccharides
2
2004
87
0.060
Why?
Mutation
4
2017
3998
0.060
Why?
Ultrasonography, Doppler, Transcranial
1
2025
42
0.060
Why?
Middle Cerebral Artery
1
2025
53
0.060
Why?
Intercellular Signaling Peptides and Proteins
2
2024
385
0.060
Why?
Cytokines
2
2024
2084
0.060
Why?
Endosomal Sorting Complexes Required for Transport
1
2025
38
0.060
Why?
DNA Methylation
2
2025
637
0.060
Why?
Case-Control Studies
2
2023
3581
0.060
Why?
Calnexin
1
2004
3
0.050
Why?
Centrifugation, Density Gradient
1
2004
40
0.050
Why?
Cycloheximide
1
2004
53
0.050
Why?
Concanavalin A
1
2004
75
0.050
Why?
Fluorescent Antibody Technique, Indirect
1
2004
47
0.050
Why?
Kinetics
2
1998
1654
0.050
Why?
Precipitin Tests
1
2004
98
0.050
Why?
Mass Spectrometry
1
2007
741
0.050
Why?
Virus Activation
1
2024
85
0.050
Why?
Multienzyme Complexes
1
2004
69
0.050
Why?
Cysteine Endopeptidases
1
2004
74
0.050
Why?
Protein Synthesis Inhibitors
1
2004
47
0.050
Why?
Time Factors
2
2025
6877
0.050
Why?
Base Sequence
1
2007
2182
0.050
Why?
Hippocampus
2
2022
920
0.050
Why?
Intermediate Filaments
1
2023
26
0.050
Why?
Disulfides
1
2004
98
0.050
Why?
Diet, High-Fat
1
2025
248
0.050
Why?
Sucrose
1
2004
111
0.050
Why?
Sensory Receptor Cells
1
2024
101
0.050
Why?
Fungal Proteins
1
2004
136
0.050
Why?
Neurites
1
2023
47
0.050
Why?
Chemokines, CXC
1
2003
72
0.050
Why?
Carbohydrate Sequence
3
1999
28
0.050
Why?
Neurofilament Proteins
1
2023
51
0.050
Why?
Diffusion Tensor Imaging
1
2023
76
0.050
Why?
beta Catenin
1
2025
252
0.050
Why?
Plasmids
1
2004
359
0.050
Why?
Imipramine
1
2022
11
0.050
Why?
Wnt Signaling Pathway
1
2024
196
0.050
Why?
Growth Disorders
1
2022
85
0.050
Why?
Retinal Ganglion Cells
1
2003
111
0.050
Why?
Hearing Loss, Sensorineural
1
2022
66
0.050
Why?
Chemokines
1
2003
227
0.050
Why?
Densitometry
1
2022
37
0.050
Why?
Gene Expression Regulation
1
2011
2602
0.050
Why?
Diffusion Magnetic Resonance Imaging
1
2023
154
0.050
Why?
Transforming Growth Factor beta
1
2024
487
0.050
Why?
Virus Internalization
1
2022
66
0.050
Why?
Polymerization
1
2022
128
0.050
Why?
Viral Proteins
1
2024
363
0.040
Why?
Protein Structure, Tertiary
1
2004
864
0.040
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
1
2022
151
0.040
Why?
Catalysis
1
2022
318
0.040
Why?
Cattle
1
2004
996
0.040
Why?
Oxidation-Reduction
1
2025
1079
0.040
Why?
Lectins
2
1998
46
0.040
Why?
Neuroimaging
1
2023
263
0.040
Why?
Tissue Plasminogen Activator
1
2023
231
0.040
Why?
Interneurons
1
2022
122
0.040
Why?
Receptors, HIV
1
2000
25
0.040
Why?
Retina
1
2003
303
0.040
Why?
DNA, Complementary
1
2021
276
0.040
Why?
Immune System
1
2022
181
0.040
Why?
Double-Blind Method
1
2025
1946
0.040
Why?
Sensitivity and Specificity
1
2025
1958
0.040
Why?
Insulin-Like Growth Factor I
1
2022
324
0.040
Why?
Organoids
1
2021
120
0.040
Why?
Teratocarcinoma
1
2000
2
0.040
Why?
Receptors, Dopamine D2
1
2000
96
0.040
Why?
Intracellular Space
1
2020
68
0.040
Why?
Pilot Projects
1
2025
1757
0.040
Why?
Acyclovir
1
2020
95
0.040
Why?
Extracellular Space
1
2020
125
0.040
Why?
Phagocytosis
1
2021
387
0.040
Why?
Cerebral Palsy
1
2021
113
0.040
Why?
Phytohemagglutinins
1
1999
28
0.040
Why?
Viral Envelope Proteins
1
2020
97
0.040
Why?
Thrombosis
1
2023
378
0.040
Why?
Cell Line
2
2022
2874
0.040
Why?
DNA, Viral
1
2021
369
0.040
Why?
Nicotine
1
2021
347
0.040
Why?
Genotype
1
2004
1873
0.040
Why?
Reactive Oxygen Species
1
2021
629
0.040
Why?
Induced Pluripotent Stem Cells
1
2021
248
0.040
Why?
Receptors, G-Protein-Coupled
1
2000
220
0.040
Why?
Gene Expression Regulation, Neoplastic
1
2024
1388
0.040
Why?
RNA, Messenger
2
2011
2817
0.040
Why?
Fetuins
1
1997
2
0.030
Why?
Asialoglycoproteins
1
1997
2
0.030
Why?
Cytidine Monophosphate N-Acetylneuraminic Acid
1
1997
3
0.030
Why?
Nervous System
1
1998
67
0.030
Why?
MicroRNAs
1
2024
680
0.030
Why?
Calcium Signaling
1
2000
249
0.030
Why?
DNA-Binding Proteins
1
2025
1476
0.030
Why?
Protein Binding
1
2004
2236
0.030
Why?
alpha-Fetoproteins
1
1997
41
0.030
Why?
Homozygote
1
2017
203
0.030
Why?
Gene Dosage
1
2017
142
0.030
Why?
Tretinoin
1
1998
122
0.030
Why?
Chromosomes, Human, Pair 21
1
2017
42
0.030
Why?
Heterozygote
1
2017
305
0.030
Why?
Transcription Factors
1
2025
1707
0.030
Why?
Carbohydrate Conformation
1
1996
14
0.030
Why?
Glycoproteins
1
1998
359
0.030
Why?
Oligosaccharides
1
1996
59
0.030
Why?
Glutathione Reductase
1
2015
25
0.030
Why?
Parietal Lobe
1
1996
60
0.030
Why?
Peroxiredoxins
1
2015
25
0.030
Why?
Substrate Specificity
1
1996
385
0.030
Why?
Brain Stem
1
1996
96
0.030
Why?
Glutathione Transferase
1
2015
102
0.030
Why?
Fetus
1
2000
801
0.030
Why?
Nervous System Diseases
1
1998
273
0.030
Why?
Acetylation
1
2015
245
0.030
Why?
Aldehydes
1
2015
144
0.030
Why?
Oxidative Phosphorylation
1
2015
194
0.030
Why?
Focus Groups
1
2017
533
0.030
Why?
Academic Medical Centers
1
2017
511
0.030
Why?
Antiviral Agents
1
2020
764
0.030
Why?
Cerebellum
1
1996
218
0.030
Why?
Interviews as Topic
1
2017
803
0.030
Why?
Risk Assessment
1
2023
3459
0.030
Why?
Glutathione
1
2015
357
0.030
Why?
Cell Differentiation
2
1998
2000
0.030
Why?
Superoxide Dismutase
1
2015
353
0.020
Why?
Mice, Transgenic
1
2017
2177
0.020
Why?
Neoplasm Proteins
1
1995
433
0.020
Why?
Lipid Metabolism
1
2015
523
0.020
Why?
SEC Translocation Channels
1
2011
10
0.020
Why?
Amino Acids
1
2015
499
0.020
Why?
Lung
1
2024
4086
0.020
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2011
98
0.020
Why?
Inflammation
1
2022
2857
0.020
Why?
Mutagenesis, Site-Directed
1
2011
374
0.020
Why?
Protein Stability
1
2011
176
0.020
Why?
Hydrophobic and Hydrophilic Interactions
1
2011
189
0.020
Why?
Cross-Sectional Studies
1
2021
5523
0.020
Why?
Genetic Vectors
1
2011
335
0.020
Why?
HeLa Cells
1
2011
639
0.020
Why?
Qualitative Research
1
2017
1434
0.020
Why?
Protein Transport
1
2011
441
0.020
Why?
RNA, Small Interfering
1
2011
626
0.020
Why?
Treatment Outcome
1
2023
10938
0.020
Why?
Promoter Regions, Genetic
1
2011
1239
0.020
Why?
Antineoplastic Agents
1
1998
2161
0.020
Why?
Transcription, Genetic
1
2011
1462
0.010
Why?
Retrospective Studies
1
2022
15860
0.010
Why?
Adolescent
1
2023
21528
0.010
Why?
In Situ Nick-End Labeling
1
2003
126
0.010
Why?
Chick Embryo
1
2003
128
0.010
Why?
Glycogen Synthase Kinase 3 beta
1
2003
73
0.010
Why?
Chemokine CXCL12
1
2003
84
0.010
Why?
Glycogen Synthase Kinase 3
1
2003
82
0.010
Why?
Receptors, CXCR4
1
2003
88
0.010
Why?
Infant
1
2017
9565
0.010
Why?
Nerve Growth Factors
1
2003
79
0.010
Why?
Cell Count
1
2003
324
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2003
129
0.010
Why?
Cyclic AMP
1
2003
220
0.010
Why?
Mitogen-Activated Protein Kinases
1
2003
317
0.010
Why?
Apelin Receptors
1
2000
4
0.010
Why?
Dopamine D2 Receptor Antagonists
1
2000
5
0.010
Why?
Apelin
1
2000
10
0.010
Why?
Adipokines
1
2000
47
0.010
Why?
Receptors, Virus
1
2000
94
0.010
Why?
Simian Immunodeficiency Virus
1
2000
91
0.010
Why?
Cell Survival
1
2003
1129
0.010
Why?
Primates
1
2000
138
0.010
Why?
Swainsonine
1
1999
1
0.010
Why?
1-Deoxynojirimycin
1
1999
1
0.010
Why?
Mannosidases
1
1999
4
0.010
Why?
Neuraminidase
1
1999
25
0.010
Why?
Tissue Distribution
1
1999
333
0.010
Why?
Phosphorylation
1
2003
1770
0.010
Why?
Transfection
1
2000
942
0.010
Why?
Biological Transport
1
1999
403
0.010
Why?
Mice, Inbred BALB C
1
2000
1261
0.010
Why?
Leukocytes, Mononuclear
1
2000
570
0.010
Why?
Solubility
1
1998
241
0.010
Why?
Pituitary Neoplasms
1
1999
189
0.010
Why?
Blotting, Western
1
1999
1229
0.010
Why?
Carrier Proteins
1
2000
739
0.010
Why?
Mice, Knockout
1
2003
3038
0.010
Why?
HIV-1
1
2000
888
0.010
Why?
Antibodies, Monoclonal
1
2000
1437
0.010
Why?
T-Lymphocytes
1
2000
1983
0.010
Why?
Coughlan's Networks
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