Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christina Coughlan

Concepts (344)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Alzheimer Disease
10
2025
595
2.240
Why?
Extracellular Vesicles
7
2025
153
1.740
Why?
Exosomes
3
2023
105
0.820
Why?
Astrocytes
4
2022
217
0.800
Why?
White Matter
2
2023
148
0.760
Why?
Gliosis
2
2023
28
0.740
Why?
Proteasome Endopeptidase Complex
2
2022
161
0.730
Why?
Glial Fibrillary Acidic Protein
2
2025
112
0.720
Why?
Sialyltransferases
8
1999
13
0.710
Why?
Amyloid beta-Protein Precursor
5
2022
67
0.680
Why?
Healthy Aging
1
2021
37
0.660
Why?
Ultracentrifugation
1
2020
52
0.660
Why?
Memory, Episodic
1
2021
53
0.660
Why?
Saccharomyces cerevisiae
5
2022
556
0.550
Why?
Amyloid beta-Peptides
5
2022
235
0.500
Why?
Proteomics
3
2024
1138
0.480
Why?
Peptide Fragments
3
2022
701
0.470
Why?
Neurons
7
2025
1621
0.450
Why?
Cognitive Dysfunction
3
2025
412
0.440
Why?
Nanoparticles
1
2020
484
0.440
Why?
Dexamethasone
7
1999
380
0.400
Why?
Brain Ischemia
2
2025
350
0.330
Why?
Islet Amyloid Polypeptide
2
2021
48
0.320
Why?
Herpes Zoster
3
2024
319
0.320
Why?
Down Syndrome
4
2022
506
0.320
Why?
Sialoglycoproteins
3
1997
160
0.280
Why?
Protein Folding
3
2005
278
0.270
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
2
2025
160
0.270
Why?
Neuroblastoma
3
1999
163
0.240
Why?
Herpesvirus 3, Human
3
2024
336
0.240
Why?
Stroke
3
2023
1158
0.240
Why?
Proteome
2
2024
485
0.230
Why?
Plasma
2
2024
221
0.230
Why?
Sodium Bicarbonate
1
2025
45
0.230
Why?
Biomarkers
8
2025
4190
0.220
Why?
Tetraspanin 28
1
2024
6
0.220
Why?
Protein Conformation
2
2005
941
0.220
Why?
Chordoma
1
2024
17
0.220
Why?
Idiopathic Pulmonary Fibrosis
2
2024
658
0.220
Why?
DNA Transposable Elements
1
2025
120
0.220
Why?
alpha-Synuclein
1
2024
43
0.220
Why?
Acidosis
1
2025
102
0.220
Why?
Amyloidogenic Proteins
1
2024
16
0.210
Why?
Mitochondria
2
2025
979
0.210
Why?
Aprotinin
1
2004
9
0.210
Why?
Varicella Zoster Virus Infection
2
2024
24
0.210
Why?
Aged, 80 and over
8
2025
7923
0.210
Why?
Vacuoles
1
2004
40
0.210
Why?
Osteoblasts
1
2024
135
0.210
Why?
Glucocorticoids
3
1999
534
0.210
Why?
Interleukin-6
2
2025
792
0.210
Why?
Recombinant Proteins
2
2007
1363
0.210
Why?
Tumor Microenvironment
2
2024
703
0.200
Why?
Humans
36
2025
141754
0.200
Why?
Neurodegenerative Diseases
1
2005
141
0.200
Why?
Bleomycin
1
2024
248
0.200
Why?
Cerebrovascular Circulation
1
2025
271
0.190
Why?
Epithelial-Mesenchymal Transition
1
2024
213
0.190
Why?
Animals
23
2025
37749
0.190
Why?
Diabetic Neuropathies
1
2023
95
0.190
Why?
Colon
1
2025
300
0.190
Why?
Apolipoprotein E4
1
2022
38
0.190
Why?
Ischemic Attack, Transient
1
2023
70
0.180
Why?
Protein Processing, Post-Translational
4
2011
464
0.180
Why?
Disease
1
2003
102
0.180
Why?
Cognition
3
2025
1228
0.180
Why?
Fatty Acids
1
2025
450
0.180
Why?
Bronchoalveolar Lavage Fluid
1
2024
650
0.180
Why?
Endoplasmic Reticulum
1
2004
265
0.180
Why?
Retinal Drusen
1
2021
31
0.180
Why?
Peptides
2
2024
979
0.180
Why?
Virion
1
2022
113
0.170
Why?
Retinal Pigment Epithelium
1
2021
77
0.170
Why?
Aldosterone
4
1999
43
0.170
Why?
Arteritis
1
2021
27
0.170
Why?
Central Nervous System Viral Diseases
1
2022
77
0.170
Why?
Chemical Precipitation
1
2020
39
0.170
Why?
Aged
12
2025
24746
0.170
Why?
Brain-Derived Neurotrophic Factor
1
2021
141
0.170
Why?
Cell Polarity
1
2021
140
0.170
Why?
Myelitis
1
2022
104
0.170
Why?
Stem Cells
1
2025
603
0.170
Why?
Adipose Tissue
1
2025
647
0.160
Why?
Epigenesis, Genetic
1
2025
663
0.160
Why?
Enterovirus D, Human
1
2022
85
0.160
Why?
Amyloid
1
2021
97
0.160
Why?
Receptors, Chemokine
1
2000
49
0.160
Why?
Cell Movement
1
2024
990
0.160
Why?
Neuromuscular Diseases
1
2022
142
0.160
Why?
Chemokine CCL2
1
2000
117
0.150
Why?
Macular Degeneration
1
2021
186
0.150
Why?
Adrenal Cortex Hormones
3
1999
501
0.150
Why?
Enterovirus Infections
1
2022
172
0.150
Why?
Fibroblasts
1
2024
1021
0.150
Why?
Wnt-5a Protein
1
2018
25
0.150
Why?
Renal Insufficiency, Chronic
1
2025
623
0.150
Why?
Signal Transduction
4
2021
5169
0.150
Why?
Aging
3
2025
1924
0.140
Why?
Frontotemporal Lobar Degeneration
1
2017
18
0.140
Why?
Cell Communication
2
2000
318
0.140
Why?
Kidney
2
2015
1482
0.130
Why?
N-Acetylneuraminic Acid
2
1999
11
0.130
Why?
Proteostasis Deficiencies
1
2017
5
0.130
Why?
Aneuploidy
1
2017
89
0.130
Why?
Melanoma
1
2024
792
0.130
Why?
tau Proteins
1
2017
95
0.130
Why?
Tumor Cells, Cultured
5
2000
962
0.130
Why?
Middle Aged
10
2025
34647
0.120
Why?
Trisomy
1
2017
79
0.120
Why?
Brain Chemistry
1
1996
117
0.120
Why?
Proteins
1
2021
1015
0.120
Why?
Isoenzymes
1
1996
302
0.120
Why?
Carcinoma, Hepatocellular
2
1997
353
0.120
Why?
Male
14
2025
70179
0.110
Why?
Models, Biological
1
2003
1828
0.110
Why?
Rats
8
2025
5637
0.110
Why?
Cystic Fibrosis
1
2005
1130
0.110
Why?
Apoptosis
3
2025
2576
0.110
Why?
Neurofilament Proteins
2
2025
62
0.110
Why?
Brain
4
2023
2868
0.100
Why?
Molecular Sequence Data
5
2015
2929
0.100
Why?
Female
13
2025
75943
0.100
Why?
Disease Models, Animal
4
2025
4421
0.100
Why?
Oxidative Stress
2
2021
1334
0.100
Why?
Mitochondrial Proteins
1
2015
261
0.100
Why?
Membrane Proteins
3
2024
1158
0.100
Why?
Enzyme Induction
3
1997
90
0.090
Why?
Nerve Tissue Proteins
1
1996
605
0.090
Why?
Obesity
1
2025
3008
0.090
Why?
Amino Acid Sequence
3
2015
2158
0.090
Why?
Transcription Factor AP-2
1
2011
82
0.090
Why?
Parkinson Disease
1
2017
571
0.080
Why?
Glioma
1
1995
427
0.080
Why?
Mice
9
2025
18109
0.080
Why?
Ethanol
1
2015
629
0.080
Why?
Mice, Inbred C57BL
4
2025
5909
0.080
Why?
Membrane Transport Proteins
1
2011
156
0.080
Why?
Adrenalectomy
4
1999
70
0.080
Why?
Palliative Care
1
2017
822
0.080
Why?
Cells, Cultured
4
2021
4212
0.080
Why?
Cell Line, Tumor
3
2024
3495
0.080
Why?
Receptors, Nicotinic
1
2011
344
0.070
Why?
Diabetes Mellitus, Type 2
1
2023
2537
0.070
Why?
Attitude of Health Personnel
1
2017
1183
0.070
Why?
Caregivers
1
2017
943
0.070
Why?
Adult
5
2025
39391
0.070
Why?
Alcoholism
1
2015
823
0.070
Why?
Glycosylation
3
1999
163
0.070
Why?
Liver
1
1996
1820
0.070
Why?
Saccharomyces cerevisiae Proteins
1
2011
403
0.070
Why?
Schizophrenia
1
2011
454
0.070
Why?
Drug Stability
1
2007
166
0.060
Why?
DNA Primers
1
2007
510
0.060
Why?
Golgi Apparatus
2
2004
100
0.060
Why?
Polysaccharides
2
2004
87
0.060
Why?
Mutation
4
2017
4015
0.060
Why?
Ubiquitin Thiolesterase
1
2025
60
0.060
Why?
Ultrasonography, Doppler, Transcranial
1
2025
44
0.060
Why?
Middle Cerebral Artery
1
2025
55
0.060
Why?
Cytokines
2
2024
2100
0.060
Why?
Intercellular Signaling Peptides and Proteins
2
2024
389
0.060
Why?
Endosomal Sorting Complexes Required for Transport
1
2025
38
0.060
Why?
DNA Methylation
2
2025
648
0.060
Why?
Case-Control Studies
2
2023
3597
0.050
Why?
Calnexin
1
2004
3
0.050
Why?
Centrifugation, Density Gradient
1
2004
40
0.050
Why?
Cycloheximide
1
2004
53
0.050
Why?
Concanavalin A
1
2004
75
0.050
Why?
Fluorescent Antibody Technique, Indirect
1
2004
47
0.050
Why?
Kinetics
2
1998
1655
0.050
Why?
Precipitin Tests
1
2004
98
0.050
Why?
Mass Spectrometry
1
2007
740
0.050
Why?
Cell Death
1
2025
387
0.050
Why?
Virus Activation
1
2024
86
0.050
Why?
Multienzyme Complexes
1
2004
66
0.050
Why?
Cysteine Endopeptidases
1
2004
74
0.050
Why?
Protein Synthesis Inhibitors
1
2004
47
0.050
Why?
Base Sequence
1
2007
2180
0.050
Why?
Intermediate Filaments
1
2023
26
0.050
Why?
Time Factors
2
2025
6966
0.050
Why?
Disulfides
1
2004
99
0.050
Why?
Diet, High-Fat
1
2025
253
0.050
Why?
Hippocampus
2
2022
940
0.050
Why?
Sucrose
1
2004
111
0.050
Why?
Sensory Receptor Cells
1
2024
101
0.050
Why?
Fungal Proteins
1
2004
137
0.050
Why?
Chemokines, CXC
1
2003
71
0.050
Why?
Carbohydrate Sequence
3
1999
28
0.050
Why?
Neurites
1
2023
51
0.050
Why?
Diffusion Tensor Imaging
1
2023
78
0.050
Why?
Plasmids
1
2004
365
0.050
Why?
beta Catenin
1
2025
258
0.050
Why?
Imipramine
1
2022
11
0.050
Why?
Wnt Signaling Pathway
1
2024
202
0.050
Why?
Inflammation
2
2025
2902
0.050
Why?
Growth Disorders
1
2022
87
0.050
Why?
Hearing Loss, Sensorineural
1
2022
68
0.050
Why?
Chemokines
1
2003
228
0.050
Why?
Retinal Ganglion Cells
1
2003
117
0.050
Why?
Densitometry
1
2022
38
0.050
Why?
Gene Expression Regulation
1
2011
2608
0.050
Why?
Diffusion Magnetic Resonance Imaging
1
2023
156
0.050
Why?
Virus Internalization
1
2022
65
0.050
Why?
Transforming Growth Factor beta
1
2024
498
0.050
Why?
Polymerization
1
2022
128
0.040
Why?
Viral Proteins
1
2024
369
0.040
Why?
Protein Structure, Tertiary
1
2004
859
0.040
Why?
Catalysis
1
2022
320
0.040
Why?
Chromatin
1
2025
533
0.040
Why?
Cattle
1
2004
998
0.040
Why?
Oxidation-Reduction
1
2025
1087
0.040
Why?
Lectins
2
1998
46
0.040
Why?
Interneurons
1
2022
124
0.040
Why?
Receptors, HIV
1
2000
25
0.040
Why?
Tissue Plasminogen Activator
1
2023
239
0.040
Why?
Neuroimaging
1
2023
281
0.040
Why?
DNA, Complementary
1
2021
274
0.040
Why?
Immune System
1
2022
183
0.040
Why?
Retina
1
2003
314
0.040
Why?
Double-Blind Method
1
2025
1989
0.040
Why?
Insulin-Like Growth Factor I
1
2022
325
0.040
Why?
Sensitivity and Specificity
1
2025
1977
0.040
Why?
Teratocarcinoma
1
2000
2
0.040
Why?
Organoids
1
2021
129
0.040
Why?
Receptors, Dopamine D2
1
2000
96
0.040
Why?
Intracellular Space
1
2020
68
0.040
Why?
Acyclovir
1
2020
95
0.040
Why?
Pilot Projects
1
2025
1826
0.040
Why?
Extracellular Space
1
2020
129
0.040
Why?
Phagocytosis
1
2021
389
0.040
Why?
Phytohemagglutinins
1
1999
29
0.040
Why?
Viral Envelope Proteins
1
2020
97
0.040
Why?
Cerebral Palsy
1
2021
121
0.040
Why?
Cell Line
2
2022
2887
0.040
Why?
DNA, Viral
1
2021
367
0.040
Why?
Thrombosis
1
2023
399
0.040
Why?
Nicotine
1
2021
350
0.040
Why?
Genotype
1
2004
1866
0.040
Why?
Reactive Oxygen Species
1
2021
634
0.040
Why?
Receptors, G-Protein-Coupled
1
2000
226
0.040
Why?
Induced Pluripotent Stem Cells
1
2021
265
0.040
Why?
RNA, Messenger
2
2011
2828
0.040
Why?
Gene Expression Regulation, Neoplastic
1
2024
1435
0.030
Why?
Fetuins
1
1997
2
0.030
Why?
Asialoglycoproteins
1
1997
2
0.030
Why?
Cytidine Monophosphate N-Acetylneuraminic Acid
1
1997
3
0.030
Why?
Nervous System
1
1998
68
0.030
Why?
Calcium Signaling
1
2000
250
0.030
Why?
MicroRNAs
1
2024
692
0.030
Why?
DNA-Binding Proteins
1
2025
1485
0.030
Why?
Protein Binding
1
2004
2242
0.030
Why?
alpha-Fetoproteins
1
1997
40
0.030
Why?
Homozygote
1
2017
201
0.030
Why?
Gene Dosage
1
2017
142
0.030
Why?
Tretinoin
1
1998
122
0.030
Why?
Chromosomes, Human, Pair 21
1
2017
42
0.030
Why?
Heterozygote
1
2017
308
0.030
Why?
Transcription Factors
1
2025
1712
0.030
Why?
Carbohydrate Conformation
1
1996
14
0.030
Why?
Glycoproteins
1
1998
358
0.030
Why?
Oligosaccharides
1
1996
59
0.030
Why?
Glutathione Reductase
1
2015
25
0.030
Why?
Parietal Lobe
1
1996
60
0.030
Why?
Peroxiredoxins
1
2015
26
0.030
Why?
Substrate Specificity
1
1996
385
0.030
Why?
Brain Stem
1
1996
96
0.030
Why?
Glutathione Transferase
1
2015
101
0.030
Why?
Fetus
1
2000
802
0.030
Why?
Nervous System Diseases
1
1998
277
0.030
Why?
Adolescent
2
2025
22130
0.030
Why?
Acetylation
1
2015
245
0.030
Why?
Aldehydes
1
2015
146
0.030
Why?
Oxidative Phosphorylation
1
2015
204
0.030
Why?
Focus Groups
1
2017
572
0.030
Why?
Antiviral Agents
1
2020
747
0.030
Why?
Academic Medical Centers
1
2017
531
0.030
Why?
Cerebellum
1
1996
218
0.030
Why?
Risk Assessment
1
2023
3508
0.030
Why?
Glutathione
1
2015
362
0.030
Why?
Interviews as Topic
1
2017
854
0.030
Why?
Cell Differentiation
2
1998
2006
0.030
Why?
Superoxide Dismutase
1
2015
352
0.020
Why?
Mice, Transgenic
1
2017
2184
0.020
Why?
Neoplasm Proteins
1
1995
434
0.020
Why?
Lipid Metabolism
1
2015
528
0.020
Why?
SEC Translocation Channels
1
2011
10
0.020
Why?
Amino Acids
1
2015
497
0.020
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2011
98
0.020
Why?
Lung
1
2024
4137
0.020
Why?
Mutagenesis, Site-Directed
1
2011
377
0.020
Why?
Protein Stability
1
2011
175
0.020
Why?
Child, Preschool
1
2025
11512
0.020
Why?
Hydrophobic and Hydrophilic Interactions
1
2011
188
0.020
Why?
Genetic Vectors
1
2011
336
0.020
Why?
Cross-Sectional Studies
1
2021
5697
0.020
Why?
HeLa Cells
1
2011
640
0.020
Why?
Protein Transport
1
2011
448
0.020
Why?
Qualitative Research
1
2017
1547
0.020
Why?
RNA, Small Interfering
1
2011
627
0.020
Why?
Young Adult
1
2025
13749
0.020
Why?
Treatment Outcome
1
2023
11181
0.020
Why?
Promoter Regions, Genetic
1
2011
1243
0.020
Why?
Antineoplastic Agents
1
1998
2169
0.020
Why?
Child
1
2025
22414
0.010
Why?
Transcription, Genetic
1
2011
1487
0.010
Why?
Retrospective Studies
1
2022
16374
0.010
Why?
In Situ Nick-End Labeling
1
2003
126
0.010
Why?
Chick Embryo
1
2003
133
0.010
Why?
Glycogen Synthase Kinase 3 beta
1
2003
73
0.010
Why?
Chemokine CXCL12
1
2003
84
0.010
Why?
Glycogen Synthase Kinase 3
1
2003
82
0.010
Why?
Receptors, CXCR4
1
2003
89
0.010
Why?
Nerve Growth Factors
1
2003
79
0.010
Why?
Infant
1
2017
9843
0.010
Why?
Cell Count
1
2003
326
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2003
129
0.010
Why?
Cyclic AMP
1
2003
219
0.010
Why?
Mitogen-Activated Protein Kinases
1
2003
317
0.010
Why?
Apelin Receptors
1
2000
4
0.010
Why?
Dopamine D2 Receptor Antagonists
1
2000
5
0.010
Why?
Apelin
1
2000
10
0.010
Why?
Adipokines
1
2000
52
0.010
Why?
Receptors, Virus
1
2000
96
0.010
Why?
Simian Immunodeficiency Virus
1
2000
92
0.010
Why?
Cell Survival
1
2003
1134
0.010
Why?
Primates
1
2000
140
0.010
Why?
Swainsonine
1
1999
1
0.010
Why?
1-Deoxynojirimycin
1
1999
1
0.010
Why?
Mannosidases
1
1999
4
0.010
Why?
Neuraminidase
1
1999
25
0.010
Why?
Tissue Distribution
1
1999
330
0.010
Why?
Phosphorylation
1
2003
1774
0.010
Why?
Transfection
1
2000
943
0.010
Why?
Biological Transport
1
1999
410
0.010
Why?
Mice, Inbred BALB C
1
2000
1275
0.010
Why?
Leukocytes, Mononuclear
1
2000
574
0.010
Why?
Solubility
1
1998
245
0.010
Why?
Blotting, Western
1
1999
1234
0.010
Why?
Pituitary Neoplasms
1
1999
197
0.010
Why?
Carrier Proteins
1
2000
748
0.010
Why?
Mice, Knockout
1
2003
3071
0.010
Why?
HIV-1
1
2000
895
0.010
Why?
Antibodies, Monoclonal
1
2000
1474
0.010
Why?
T-Lymphocytes
1
2000
2007
0.010
Why?
Coughlan's Networks
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