Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christina Coughlan

Concepts (364)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Alzheimer Disease
11
2026
621
2.310
Why?
Extracellular Vesicles
9
2025
171
2.050
Why?
Exosomes
3
2023
104
0.800
Why?
Astrocytes
4
2022
222
0.780
Why?
Glial Fibrillary Acidic Protein
3
2026
124
0.760
Why?
White Matter
2
2023
153
0.750
Why?
Gliosis
2
2023
29
0.720
Why?
Proteasome Endopeptidase Complex
2
2022
159
0.710
Why?
Sialyltransferases
8
1999
13
0.700
Why?
Amyloid beta-Protein Precursor
5
2022
64
0.660
Why?
Ultracentrifugation
1
2020
51
0.650
Why?
Healthy Aging
1
2021
40
0.650
Why?
Memory, Episodic
1
2021
54
0.640
Why?
Amyloid beta-Peptides
7
2026
241
0.590
Why?
Neurons
8
2026
1640
0.560
Why?
Saccharomyces cerevisiae
5
2022
579
0.530
Why?
Proteomics
4
2026
1195
0.500
Why?
Peptide Fragments
3
2022
699
0.460
Why?
Nanoparticles
1
2020
519
0.410
Why?
Cognitive Dysfunction
3
2025
461
0.410
Why?
Neurodegenerative Diseases
2
2026
151
0.400
Why?
Dexamethasone
7
1999
372
0.390
Why?
Biomarkers
10
2026
4271
0.350
Why?
Brain Ischemia
2
2025
358
0.320
Why?
Herpes Zoster
3
2024
315
0.320
Why?
Islet Amyloid Polypeptide
2
2021
48
0.320
Why?
Down Syndrome
4
2022
534
0.310
Why?
Sialoglycoproteins
3
1997
158
0.270
Why?
Protein Folding
3
2005
279
0.270
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
2
2025
161
0.260
Why?
Aging
4
2026
1966
0.250
Why?
Interleukin-6
3
2026
780
0.250
Why?
Oligoclonal Bands
1
2026
26
0.240
Why?
Herpesvirus 3, Human
3
2024
336
0.230
Why?
Neuroblastoma
3
1999
174
0.230
Why?
Aged, 80 and over
9
2026
8265
0.230
Why?
Stroke
3
2023
1256
0.220
Why?
Humans
41
2026
144759
0.220
Why?
Plasma
2
2024
225
0.220
Why?
Proteome
2
2024
518
0.220
Why?
Sodium Bicarbonate
1
2025
47
0.220
Why?
Protein Conformation
2
2005
946
0.220
Why?
Tetraspanin 28
1
2024
6
0.220
Why?
Intra-Abdominal Fat
1
2025
100
0.220
Why?
Chordoma
1
2024
17
0.220
Why?
DNA Transposable Elements
1
2025
122
0.210
Why?
alpha-Synuclein
1
2024
46
0.210
Why?
Acidosis
1
2025
105
0.210
Why?
Fluorescence Resonance Energy Transfer
1
2025
178
0.210
Why?
Idiopathic Pulmonary Fibrosis
2
2024
691
0.210
Why?
Amyloidogenic Proteins
1
2024
16
0.210
Why?
Aprotinin
1
2004
11
0.210
Why?
Mitochondria
2
2025
984
0.210
Why?
Varicella Zoster Virus Infection
2
2024
27
0.210
Why?
Vacuoles
1
2004
38
0.210
Why?
Osteoblasts
1
2024
145
0.200
Why?
Glucocorticoids
3
1999
535
0.200
Why?
Carcinogenesis
1
2025
229
0.200
Why?
Recombinant Proteins
2
2007
1370
0.200
Why?
Central Nervous System
1
2026
281
0.200
Why?
Animals
24
2025
38058
0.200
Why?
Tumor Microenvironment
2
2024
732
0.200
Why?
Cerebrovascular Circulation
1
2025
280
0.190
Why?
Bleomycin
1
2024
253
0.190
Why?
Epithelial-Mesenchymal Transition
1
2024
219
0.190
Why?
Colon
1
2025
304
0.180
Why?
Diabetic Neuropathies
1
2023
99
0.180
Why?
Ischemic Attack, Transient
1
2023
71
0.180
Why?
Apolipoprotein E4
1
2022
41
0.180
Why?
Disease
1
2003
98
0.180
Why?
tau Proteins
2
2026
115
0.180
Why?
Carcinoma, Pancreatic Ductal
1
2025
291
0.180
Why?
Protein Processing, Post-Translational
4
2011
477
0.180
Why?
Fatty Acids
1
2025
450
0.180
Why?
Bronchoalveolar Lavage Fluid
1
2024
636
0.180
Why?
Obesity
2
2025
3077
0.170
Why?
Cognition
3
2025
1266
0.170
Why?
Aged
13
2026
25913
0.170
Why?
Immunoglobulin G
1
2026
893
0.170
Why?
Endoplasmic Reticulum
1
2004
266
0.170
Why?
Retinal Drusen
1
2021
31
0.170
Why?
Virion
1
2022
111
0.170
Why?
Peptides
2
2024
995
0.170
Why?
Retinal Pigment Epithelium
1
2021
80
0.170
Why?
Aldosterone
4
1999
43
0.170
Why?
Arteritis
1
2021
25
0.170
Why?
Central Nervous System Viral Diseases
1
2022
78
0.160
Why?
Chemical Precipitation
1
2020
39
0.160
Why?
Cell Polarity
1
2021
137
0.160
Why?
Health Status
1
2026
836
0.160
Why?
Myelitis
1
2022
107
0.160
Why?
Neurofilament Proteins
3
2026
78
0.160
Why?
Brain-Derived Neurotrophic Factor
1
2021
148
0.160
Why?
Stem Cells
1
2025
626
0.160
Why?
Adipose Tissue
1
2025
652
0.160
Why?
Enterovirus D, Human
1
2022
87
0.160
Why?
Epigenesis, Genetic
1
2025
684
0.160
Why?
Amyloid
1
2021
92
0.160
Why?
Multiple Sclerosis
1
2026
484
0.160
Why?
Middle Aged
13
2026
35875
0.160
Why?
Cell Movement
1
2024
965
0.160
Why?
Receptors, Chemokine
1
2000
47
0.160
Why?
Neuromuscular Diseases
1
2022
146
0.150
Why?
Inflammation
3
2026
2878
0.150
Why?
Chemokine CCL2
1
2000
115
0.150
Why?
Adrenal Cortex Hormones
3
1999
478
0.150
Why?
Macular Degeneration
1
2021
191
0.150
Why?
Enterovirus Infections
1
2022
173
0.150
Why?
Male
18
2026
72315
0.140
Why?
Wnt-5a Protein
1
2018
24
0.140
Why?
Renal Insufficiency, Chronic
1
2025
653
0.140
Why?
Fibroblasts
1
2024
1034
0.140
Why?
Signal Transduction
4
2021
5226
0.140
Why?
Cell Line, Tumor
5
2025
3540
0.140
Why?
Frontotemporal Lobar Degeneration
1
2017
19
0.130
Why?
Female
17
2026
78271
0.130
Why?
Melanoma
1
2024
761
0.130
Why?
Cell Communication
2
2000
324
0.130
Why?
Kidney
2
2015
1495
0.130
Why?
N-Acetylneuraminic Acid
2
1999
16
0.130
Why?
Colorectal Neoplasms
1
2025
845
0.130
Why?
Proteostasis Deficiencies
1
2017
5
0.130
Why?
Pancreatic Neoplasms
1
2025
919
0.130
Why?
Aneuploidy
1
2017
90
0.130
Why?
Tumor Cells, Cultured
5
2000
919
0.130
Why?
Glycosylation
4
2026
172
0.120
Why?
Trisomy
1
2017
78
0.120
Why?
Brain Chemistry
1
1996
116
0.120
Why?
Proteins
1
2021
1021
0.110
Why?
Isoenzymes
1
1996
299
0.110
Why?
Endosomal Sorting Complexes Required for Transport
2
2025
46
0.110
Why?
Carcinoma, Hepatocellular
2
1997
370
0.110
Why?
Rats
8
2025
5597
0.110
Why?
Apoptosis
3
2025
2430
0.110
Why?
Models, Biological
1
2003
1821
0.110
Why?
Cystic Fibrosis
1
2005
1158
0.110
Why?
Adult
8
2026
40449
0.100
Why?
Molecular Sequence Data
5
2015
2930
0.100
Why?
Brain
4
2023
2933
0.100
Why?
Disease Models, Animal
4
2025
4557
0.100
Why?
Mice
10
2025
18339
0.100
Why?
Oxidative Stress
2
2021
1339
0.100
Why?
Mitochondrial Proteins
1
2015
262
0.100
Why?
Membrane Proteins
3
2024
1166
0.090
Why?
Enzyme Induction
3
1997
88
0.090
Why?
Nerve Tissue Proteins
1
1996
592
0.090
Why?
Amino Acid Sequence
3
2015
2155
0.090
Why?
Transcription Factor AP-2
1
2011
82
0.090
Why?
Glioma
1
1995
425
0.080
Why?
Parkinson Disease
1
2017
600
0.080
Why?
Ethanol
1
2015
627
0.080
Why?
Mice, Inbred C57BL
4
2025
5992
0.080
Why?
Membrane Transport Proteins
1
2011
154
0.080
Why?
Adrenalectomy
4
1999
71
0.080
Why?
Cells, Cultured
4
2021
4154
0.080
Why?
Diabetes Mellitus, Type 1
1
2026
3890
0.070
Why?
Receptors, Nicotinic
1
2011
321
0.070
Why?
Attitude of Health Personnel
1
2017
1185
0.070
Why?
Diabetes Mellitus, Type 2
1
2023
2583
0.070
Why?
Palliative Care
1
2017
1002
0.070
Why?
Alcoholism
1
2015
817
0.070
Why?
Caregivers
1
2017
1049
0.070
Why?
DNA-Binding Proteins
2
2025
1499
0.070
Why?
Schizophrenia
1
2011
446
0.060
Why?
Saccharomyces cerevisiae Proteins
1
2011
419
0.060
Why?
Transcription Factors
2
2025
1741
0.060
Why?
Drug Stability
1
2007
164
0.060
Why?
Liver
1
1996
1887
0.060
Why?
Chemokine CXCL5
1
2026
19
0.060
Why?
DNA Primers
1
2007
512
0.060
Why?
Chemokine CXCL9
1
2026
38
0.060
Why?
Golgi Apparatus
2
2004
100
0.060
Why?
Polysaccharides
2
2004
87
0.060
Why?
Mutation
4
2017
4089
0.060
Why?
Ubiquitin Thiolesterase
1
2025
68
0.060
Why?
Middle Cerebral Artery
1
2025
56
0.060
Why?
Protein Aggregates
1
2026
86
0.060
Why?
Cytokines
2
2024
2061
0.060
Why?
Ultrasonography, Doppler, Transcranial
1
2025
48
0.060
Why?
Intercellular Signaling Peptides and Proteins
2
2024
381
0.060
Why?
DNA Methylation
2
2025
681
0.050
Why?
Case-Control Studies
2
2023
3604
0.050
Why?
Calnexin
1
2004
3
0.050
Why?
Centrifugation, Density Gradient
1
2004
40
0.050
Why?
Cycloheximide
1
2004
46
0.050
Why?
Concanavalin A
1
2004
71
0.050
Why?
Fluorescent Antibody Technique, Indirect
1
2004
44
0.050
Why?
Kinetics
2
1998
1627
0.050
Why?
Precipitin Tests
1
2004
93
0.050
Why?
Cell Death
1
2025
383
0.050
Why?
Mass Spectrometry
1
2007
750
0.050
Why?
Fluorescent Dyes
1
2025
329
0.050
Why?
Multienzyme Complexes
1
2004
67
0.050
Why?
Cysteine Endopeptidases
1
2004
73
0.050
Why?
Base Sequence
1
2007
2190
0.050
Why?
Virus Activation
1
2024
95
0.050
Why?
Protein Synthesis Inhibitors
1
2004
48
0.050
Why?
Intermediate Filaments
1
2023
25
0.050
Why?
Glycolysis
1
2025
339
0.050
Why?
Disulfides
1
2004
96
0.050
Why?
Time Factors
2
2025
7173
0.050
Why?
Sensory Receptor Cells
1
2024
101
0.050
Why?
Diet, High-Fat
1
2025
261
0.050
Why?
Sucrose
1
2004
112
0.050
Why?
Hippocampus
2
2022
965
0.050
Why?
Chemokines, CXC
1
2003
68
0.050
Why?
Fungal Proteins
1
2004
145
0.050
Why?
Carbohydrate Sequence
3
1999
28
0.050
Why?
Neurites
1
2023
50
0.050
Why?
Diffusion Tensor Imaging
1
2023
73
0.050
Why?
beta Catenin
1
2025
252
0.050
Why?
Plasmids
1
2004
379
0.050
Why?
Interferon-gamma
1
2026
784
0.050
Why?
Imipramine
1
2022
11
0.050
Why?
Growth Disorders
1
2022
86
0.050
Why?
Cross-Sectional Studies
2
2026
5868
0.050
Why?
Wnt Signaling Pathway
1
2024
210
0.050
Why?
Chemokines
1
2003
218
0.050
Why?
Gene Expression Regulation
1
2011
2608
0.050
Why?
Densitometry
1
2022
37
0.050
Why?
Retinal Ganglion Cells
1
2003
121
0.050
Why?
Hearing Loss, Sensorineural
1
2022
73
0.040
Why?
Diffusion Magnetic Resonance Imaging
1
2023
154
0.040
Why?
Transforming Growth Factor beta
1
2024
479
0.040
Why?
Virus Internalization
1
2022
65
0.040
Why?
Polymerization
1
2022
130
0.040
Why?
Viral Proteins
1
2024
355
0.040
Why?
Protein Structure, Tertiary
1
2004
862
0.040
Why?
Catalysis
1
2022
322
0.040
Why?
Cattle
1
2004
1000
0.040
Why?
Oxidation-Reduction
1
2025
1087
0.040
Why?
Lectins
2
1998
44
0.040
Why?
Chromatin
1
2025
561
0.040
Why?
Mice, Knockout
2
2025
3121
0.040
Why?
Interneurons
1
2022
128
0.040
Why?
Receptors, HIV
1
2000
23
0.040
Why?
Tissue Plasminogen Activator
1
2023
244
0.040
Why?
Neuroimaging
1
2023
289
0.040
Why?
Immune System
1
2022
179
0.040
Why?
DNA, Complementary
1
2021
276
0.040
Why?
Retina
1
2003
324
0.040
Why?
Insulin-Like Growth Factor I
1
2022
319
0.040
Why?
Double-Blind Method
1
2025
2029
0.040
Why?
Sensitivity and Specificity
1
2025
1985
0.040
Why?
Teratocarcinoma
1
2000
2
0.040
Why?
Receptors, Dopamine D2
1
2000
93
0.040
Why?
Phagocytosis
1
2021
299
0.040
Why?
Intracellular Space
1
2020
66
0.040
Why?
Organoids
1
2021
141
0.040
Why?
Acyclovir
1
2020
96
0.040
Why?
Extracellular Space
1
2020
120
0.040
Why?
Pilot Projects
1
2025
1886
0.040
Why?
Phytohemagglutinins
1
1999
29
0.040
Why?
Viral Envelope Proteins
1
2020
98
0.040
Why?
Cell Line
2
2022
2882
0.040
Why?
Cerebral Palsy
1
2021
132
0.040
Why?
Thrombosis
1
2023
393
0.040
Why?
DNA, Viral
1
2021
358
0.040
Why?
Nicotine
1
2021
331
0.040
Why?
Genotype
1
2004
1833
0.040
Why?
Reactive Oxygen Species
1
2021
621
0.040
Why?
Biomarkers, Tumor
1
2025
1313
0.040
Why?
Induced Pluripotent Stem Cells
1
2021
276
0.030
Why?
Receptors, G-Protein-Coupled
1
2000
233
0.030
Why?
Gene Expression Regulation, Neoplastic
1
2024
1455
0.030
Why?
RNA, Messenger
2
2011
2832
0.030
Why?
Asialoglycoproteins
1
1997
2
0.030
Why?
Fetuins
1
1997
3
0.030
Why?
MicroRNAs
1
2024
701
0.030
Why?
Cytidine Monophosphate N-Acetylneuraminic Acid
1
1997
3
0.030
Why?
Calcium Signaling
1
2000
251
0.030
Why?
Nervous System
1
1998
70
0.030
Why?
alpha-Fetoproteins
1
1997
40
0.030
Why?
Protein Binding
1
2004
2273
0.030
Why?
Homozygote
1
2017
199
0.030
Why?
Gene Dosage
1
2017
148
0.030
Why?
Tretinoin
1
1998
124
0.030
Why?
Chromosomes, Human, Pair 21
1
2017
42
0.030
Why?
Heterozygote
1
2017
315
0.030
Why?
Carbohydrate Conformation
1
1996
15
0.030
Why?
Glycoproteins
1
1998
355
0.030
Why?
Oligosaccharides
1
1996
60
0.030
Why?
Parietal Lobe
1
1996
60
0.030
Why?
Glutathione Reductase
1
2015
25
0.030
Why?
Peroxiredoxins
1
2015
26
0.030
Why?
Substrate Specificity
1
1996
388
0.030
Why?
Brain Stem
1
1996
95
0.030
Why?
Glutathione Transferase
1
2015
100
0.030
Why?
Fetus
1
2000
803
0.030
Why?
Adolescent
2
2025
22428
0.030
Why?
Nervous System Diseases
1
1998
284
0.030
Why?
Acetylation
1
2015
252
0.030
Why?
Aldehydes
1
2015
142
0.030
Why?
Oxidative Phosphorylation
1
2015
210
0.030
Why?
Focus Groups
1
2017
573
0.030
Why?
Academic Medical Centers
1
2017
547
0.030
Why?
Antiviral Agents
1
2020
767
0.030
Why?
Cerebellum
1
1996
223
0.030
Why?
Glutathione
1
2015
375
0.020
Why?
Risk Assessment
1
2023
3671
0.020
Why?
Superoxide Dismutase
1
2015
301
0.020
Why?
Cell Differentiation
2
1998
2050
0.020
Why?
Interviews as Topic
1
2017
901
0.020
Why?
Mice, Transgenic
1
2017
2182
0.020
Why?
Neoplasm Proteins
1
1995
442
0.020
Why?
Lipid Metabolism
1
2015
527
0.020
Why?
Risk Factors
1
2026
10779
0.020
Why?
SEC Translocation Channels
1
2011
9
0.020
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2011
93
0.020
Why?
Amino Acids
1
2015
521
0.020
Why?
Lung
1
2024
4109
0.020
Why?
Mutagenesis, Site-Directed
1
2011
381
0.020
Why?
Protein Stability
1
2011
178
0.020
Why?
Hydrophobic and Hydrophilic Interactions
1
2011
192
0.020
Why?
Child, Preschool
1
2025
11787
0.020
Why?
Genetic Vectors
1
2011
337
0.020
Why?
HeLa Cells
1
2011
650
0.020
Why?
Protein Transport
1
2011
441
0.020
Why?
Qualitative Research
1
2017
1671
0.020
Why?
RNA, Small Interfering
1
2011
635
0.020
Why?
Young Adult
1
2025
14105
0.020
Why?
Treatment Outcome
1
2023
11679
0.020
Why?
Promoter Regions, Genetic
1
2011
1257
0.020
Why?
Antineoplastic Agents
1
1998
2194
0.020
Why?
Child
1
2025
22633
0.010
Why?
Transcription, Genetic
1
2011
1496
0.010
Why?
Retrospective Studies
1
2022
17066
0.010
Why?
In Situ Nick-End Labeling
1
2003
121
0.010
Why?
Chick Embryo
1
2003
132
0.010
Why?
Glycogen Synthase Kinase 3 beta
1
2003
72
0.010
Why?
Glycogen Synthase Kinase 3
1
2003
81
0.010
Why?
Chemokine CXCL12
1
2003
89
0.010
Why?
Nerve Growth Factors
1
2003
78
0.010
Why?
Receptors, CXCR4
1
2003
91
0.010
Why?
Infant
1
2017
10034
0.010
Why?
Cell Count
1
2003
320
0.010
Why?
Cyclic AMP
1
2003
209
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2003
125
0.010
Why?
Mitogen-Activated Protein Kinases
1
2003
292
0.010
Why?
Apelin Receptors
1
2000
4
0.010
Why?
Dopamine D2 Receptor Antagonists
1
2000
5
0.010
Why?
Apelin
1
2000
10
0.010
Why?
Adipokines
1
2000
57
0.010
Why?
Receptors, Virus
1
2000
96
0.010
Why?
Simian Immunodeficiency Virus
1
2000
92
0.010
Why?
Cell Survival
1
2003
1098
0.010
Why?
Primates
1
2000
132
0.010
Why?
Swainsonine
1
1999
1
0.010
Why?
1-Deoxynojirimycin
1
1999
1
0.010
Why?
Mannosidases
1
1999
3
0.010
Why?
Neuraminidase
1
1999
24
0.010
Why?
Tissue Distribution
1
1999
327
0.010
Why?
Phosphorylation
1
2003
1732
0.010
Why?
Transfection
1
2000
940
0.010
Why?
Biological Transport
1
1999
417
0.010
Why?
Leukocytes, Mononuclear
1
2000
573
0.010
Why?
Mice, Inbred BALB C
1
2000
1253
0.010
Why?
Solubility
1
1998
242
0.010
Why?
Blotting, Western
1
1999
1187
0.010
Why?
Pituitary Neoplasms
1
1999
190
0.010
Why?
Carrier Proteins
1
2000
737
0.010
Why?
HIV-1
1
2000
896
0.010
Why?
Antibodies, Monoclonal
1
2000
1519
0.010
Why?
T-Lymphocytes
1
2000
1982
0.010
Why?
Coughlan's Networks
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