Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christina Coughlan

Concepts (364)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Alzheimer Disease
11
2026
622
2.300
Why?
Extracellular Vesicles
9
2025
171
2.040
Why?
Exosomes
3
2023
104
0.800
Why?
Astrocytes
4
2022
228
0.780
Why?
Glial Fibrillary Acidic Protein
3
2026
125
0.750
Why?
White Matter
2
2023
153
0.740
Why?
Gliosis
2
2023
29
0.720
Why?
Proteasome Endopeptidase Complex
2
2022
153
0.710
Why?
Sialyltransferases
8
1999
13
0.690
Why?
Amyloid beta-Protein Precursor
5
2022
64
0.660
Why?
Ultracentrifugation
1
2020
50
0.640
Why?
Healthy Aging
1
2021
40
0.640
Why?
Memory, Episodic
1
2021
55
0.640
Why?
Amyloid beta-Peptides
7
2026
243
0.590
Why?
Neurons
8
2026
1639
0.560
Why?
Saccharomyces cerevisiae
5
2022
579
0.530
Why?
Proteomics
4
2026
1183
0.500
Why?
Peptide Fragments
3
2022
691
0.460
Why?
Nanoparticles
1
2020
512
0.410
Why?
Cognitive Dysfunction
3
2025
464
0.410
Why?
Neurodegenerative Diseases
2
2026
150
0.390
Why?
Dexamethasone
7
1999
366
0.390
Why?
Biomarkers
10
2026
4261
0.350
Why?
Brain Ischemia
2
2025
358
0.320
Why?
Herpes Zoster
3
2024
315
0.320
Why?
Islet Amyloid Polypeptide
2
2021
48
0.310
Why?
Down Syndrome
4
2022
522
0.310
Why?
Sialoglycoproteins
3
1997
157
0.270
Why?
Protein Folding
3
2005
277
0.270
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
2
2025
161
0.260
Why?
Aging
4
2026
1938
0.250
Why?
Interleukin-6
3
2026
770
0.250
Why?
Oligoclonal Bands
1
2026
26
0.230
Why?
Herpesvirus 3, Human
3
2024
337
0.230
Why?
Neuroblastoma
3
1999
174
0.230
Why?
Aged, 80 and over
9
2026
8284
0.230
Why?
Stroke
3
2023
1262
0.220
Why?
Humans
41
2026
144671
0.220
Why?
Plasma
2
2024
223
0.220
Why?
Proteome
2
2024
515
0.220
Why?
Sodium Bicarbonate
1
2025
47
0.220
Why?
Protein Conformation
2
2005
935
0.220
Why?
Tetraspanin 28
1
2024
6
0.220
Why?
Intra-Abdominal Fat
1
2025
100
0.220
Why?
Chordoma
1
2024
17
0.210
Why?
DNA Transposable Elements
1
2025
125
0.210
Why?
alpha-Synuclein
1
2024
45
0.210
Why?
Acidosis
1
2025
105
0.210
Why?
Fluorescence Resonance Energy Transfer
1
2025
177
0.210
Why?
Idiopathic Pulmonary Fibrosis
2
2024
691
0.210
Why?
Amyloidogenic Proteins
1
2024
16
0.210
Why?
Aprotinin
1
2004
9
0.210
Why?
Mitochondria
2
2025
984
0.210
Why?
Varicella Zoster Virus Infection
2
2024
27
0.200
Why?
Vacuoles
1
2004
38
0.200
Why?
Osteoblasts
1
2024
146
0.200
Why?
Glucocorticoids
3
1999
528
0.200
Why?
Recombinant Proteins
2
2007
1363
0.200
Why?
Carcinogenesis
1
2025
227
0.200
Why?
Central Nervous System
1
2026
279
0.200
Why?
Animals
24
2025
37948
0.200
Why?
Tumor Microenvironment
2
2024
729
0.200
Why?
Epithelial-Mesenchymal Transition
1
2024
211
0.190
Why?
Bleomycin
1
2024
253
0.190
Why?
Cerebrovascular Circulation
1
2025
289
0.190
Why?
Colon
1
2025
307
0.180
Why?
Diabetic Neuropathies
1
2023
99
0.180
Why?
Ischemic Attack, Transient
1
2023
71
0.180
Why?
Apolipoprotein E4
1
2022
41
0.180
Why?
Disease
1
2003
98
0.180
Why?
tau Proteins
2
2026
115
0.180
Why?
Protein Processing, Post-Translational
4
2011
466
0.180
Why?
Carcinoma, Pancreatic Ductal
1
2025
294
0.180
Why?
Fatty Acids
1
2025
454
0.180
Why?
Bronchoalveolar Lavage Fluid
1
2024
630
0.170
Why?
Obesity
2
2025
3070
0.170
Why?
Cognition
3
2025
1263
0.170
Why?
Immunoglobulin G
1
2026
886
0.170
Why?
Aged
13
2026
25955
0.170
Why?
Endoplasmic Reticulum
1
2004
264
0.170
Why?
Retinal Drusen
1
2021
31
0.170
Why?
Peptides
2
2024
989
0.170
Why?
Virion
1
2022
111
0.170
Why?
Retinal Pigment Epithelium
1
2021
79
0.170
Why?
Arteritis
1
2021
23
0.170
Why?
Aldosterone
4
1999
42
0.170
Why?
Central Nervous System Viral Diseases
1
2022
78
0.160
Why?
Chemical Precipitation
1
2020
39
0.160
Why?
Cell Polarity
1
2021
137
0.160
Why?
Health Status
1
2026
834
0.160
Why?
Myelitis
1
2022
107
0.160
Why?
Neurofilament Proteins
3
2026
79
0.160
Why?
Brain-Derived Neurotrophic Factor
1
2021
151
0.160
Why?
Stem Cells
1
2025
621
0.160
Why?
Epigenesis, Genetic
1
2025
669
0.160
Why?
Adipose Tissue
1
2025
643
0.160
Why?
Enterovirus D, Human
1
2022
87
0.160
Why?
Multiple Sclerosis
1
2026
485
0.160
Why?
Amyloid
1
2021
90
0.160
Why?
Middle Aged
13
2026
35971
0.160
Why?
Cell Movement
1
2024
959
0.160
Why?
Receptors, Chemokine
1
2000
47
0.150
Why?
Neuromuscular Diseases
1
2022
146
0.150
Why?
Inflammation
3
2026
2870
0.150
Why?
Chemokine CCL2
1
2000
112
0.150
Why?
Adrenal Cortex Hormones
3
1999
480
0.150
Why?
Macular Degeneration
1
2021
190
0.150
Why?
Enterovirus Infections
1
2022
173
0.150
Why?
Male
18
2026
72431
0.140
Why?
Wnt-5a Protein
1
2018
24
0.140
Why?
Fibroblasts
1
2024
1019
0.140
Why?
Signal Transduction
4
2021
5185
0.140
Why?
Renal Insufficiency, Chronic
1
2025
657
0.140
Why?
Cell Line, Tumor
5
2025
3523
0.140
Why?
Frontotemporal Lobar Degeneration
1
2017
19
0.130
Why?
Female
17
2026
78304
0.130
Why?
Melanoma
1
2024
757
0.130
Why?
Kidney
2
2015
1495
0.130
Why?
Cell Communication
2
2000
325
0.130
Why?
N-Acetylneuraminic Acid
2
1999
16
0.130
Why?
Colorectal Neoplasms
1
2025
849
0.130
Why?
Proteostasis Deficiencies
1
2017
5
0.130
Why?
Pancreatic Neoplasms
1
2025
926
0.130
Why?
Aneuploidy
1
2017
90
0.130
Why?
Tumor Cells, Cultured
5
2000
881
0.130
Why?
Glycosylation
4
2026
161
0.120
Why?
Trisomy
1
2017
78
0.120
Why?
Brain Chemistry
1
1996
116
0.120
Why?
Isoenzymes
1
1996
297
0.110
Why?
Proteins
1
2021
1016
0.110
Why?
Apoptosis
3
2025
2397
0.110
Why?
Endosomal Sorting Complexes Required for Transport
2
2025
46
0.110
Why?
Carcinoma, Hepatocellular
2
1997
370
0.110
Why?
Rats
8
2025
5570
0.110
Why?
Models, Biological
1
2003
1811
0.110
Why?
Cystic Fibrosis
1
2005
1166
0.110
Why?
Adult
8
2026
40489
0.100
Why?
Molecular Sequence Data
5
2015
2909
0.100
Why?
Brain
4
2023
2934
0.100
Why?
Disease Models, Animal
4
2025
4539
0.100
Why?
Mice
10
2025
18261
0.100
Why?
Oxidative Stress
2
2021
1338
0.100
Why?
Mitochondrial Proteins
1
2015
262
0.100
Why?
Membrane Proteins
3
2024
1159
0.090
Why?
Nerve Tissue Proteins
1
1996
590
0.090
Why?
Enzyme Induction
3
1997
88
0.090
Why?
Amino Acid Sequence
3
2015
2136
0.090
Why?
Transcription Factor AP-2
1
2011
82
0.090
Why?
Glioma
1
1995
429
0.080
Why?
Parkinson Disease
1
2017
600
0.080
Why?
Ethanol
1
2015
627
0.080
Why?
Mice, Inbred C57BL
4
2025
5967
0.080
Why?
Membrane Transport Proteins
1
2011
153
0.080
Why?
Adrenalectomy
4
1999
68
0.080
Why?
Cells, Cultured
4
2021
4110
0.080
Why?
Diabetes Mellitus, Type 1
1
2026
3910
0.070
Why?
Receptors, Nicotinic
1
2011
328
0.070
Why?
Attitude of Health Personnel
1
2017
1180
0.070
Why?
Diabetes Mellitus, Type 2
1
2023
2573
0.070
Why?
Palliative Care
1
2017
1011
0.070
Why?
Alcoholism
1
2015
813
0.070
Why?
Caregivers
1
2017
1062
0.070
Why?
DNA-Binding Proteins
2
2025
1484
0.070
Why?
Schizophrenia
1
2011
443
0.060
Why?
Saccharomyces cerevisiae Proteins
1
2011
418
0.060
Why?
Transcription Factors
2
2025
1726
0.060
Why?
Liver
1
1996
1889
0.060
Why?
Drug Stability
1
2007
169
0.060
Why?
Chemokine CXCL5
1
2026
19
0.060
Why?
DNA Primers
1
2007
507
0.060
Why?
Chemokine CXCL9
1
2026
38
0.060
Why?
Golgi Apparatus
2
2004
99
0.060
Why?
Polysaccharides
2
2004
86
0.060
Why?
Mutation
4
2017
4081
0.060
Why?
Ubiquitin Thiolesterase
1
2025
68
0.060
Why?
Cytokines
2
2024
2045
0.060
Why?
Middle Cerebral Artery
1
2025
56
0.060
Why?
Protein Aggregates
1
2026
84
0.060
Why?
Intercellular Signaling Peptides and Proteins
2
2024
376
0.060
Why?
Ultrasonography, Doppler, Transcranial
1
2025
48
0.060
Why?
DNA Methylation
2
2025
664
0.050
Why?
Case-Control Studies
2
2023
3603
0.050
Why?
Calnexin
1
2004
3
0.050
Why?
Centrifugation, Density Gradient
1
2004
36
0.050
Why?
Kinetics
2
1998
1603
0.050
Why?
Cycloheximide
1
2004
42
0.050
Why?
Concanavalin A
1
2004
71
0.050
Why?
Fluorescent Antibody Technique, Indirect
1
2004
44
0.050
Why?
Precipitin Tests
1
2004
90
0.050
Why?
Mass Spectrometry
1
2007
743
0.050
Why?
Cell Death
1
2025
382
0.050
Why?
Cysteine Endopeptidases
1
2004
69
0.050
Why?
Multienzyme Complexes
1
2004
65
0.050
Why?
Fluorescent Dyes
1
2025
333
0.050
Why?
Base Sequence
1
2007
2177
0.050
Why?
Virus Activation
1
2024
95
0.050
Why?
Protein Synthesis Inhibitors
1
2004
48
0.050
Why?
Intermediate Filaments
1
2023
25
0.050
Why?
Disulfides
1
2004
94
0.050
Why?
Glycolysis
1
2025
341
0.050
Why?
Time Factors
2
2025
7140
0.050
Why?
Sensory Receptor Cells
1
2024
98
0.050
Why?
Diet, High-Fat
1
2025
261
0.050
Why?
Sucrose
1
2004
114
0.050
Why?
Hippocampus
2
2022
966
0.050
Why?
Chemokines, CXC
1
2003
68
0.050
Why?
Fungal Proteins
1
2004
145
0.050
Why?
Carbohydrate Sequence
3
1999
29
0.050
Why?
Neurites
1
2023
50
0.050
Why?
Diffusion Tensor Imaging
1
2023
75
0.050
Why?
beta Catenin
1
2025
252
0.050
Why?
Plasmids
1
2004
375
0.050
Why?
Interferon-gamma
1
2026
781
0.050
Why?
Imipramine
1
2022
11
0.050
Why?
Growth Disorders
1
2022
86
0.050
Why?
Cross-Sectional Studies
2
2026
5870
0.050
Why?
Wnt Signaling Pathway
1
2024
210
0.050
Why?
Chemokines
1
2003
218
0.050
Why?
Gene Expression Regulation
1
2011
2591
0.050
Why?
Retinal Ganglion Cells
1
2003
115
0.050
Why?
Densitometry
1
2022
35
0.040
Why?
Hearing Loss, Sensorineural
1
2022
73
0.040
Why?
Diffusion Magnetic Resonance Imaging
1
2023
154
0.040
Why?
Transforming Growth Factor beta
1
2024
475
0.040
Why?
Virus Internalization
1
2022
65
0.040
Why?
Viral Proteins
1
2024
353
0.040
Why?
Polymerization
1
2022
130
0.040
Why?
Protein Structure, Tertiary
1
2004
849
0.040
Why?
Catalysis
1
2022
319
0.040
Why?
Cattle
1
2004
975
0.040
Why?
Chromatin
1
2025
554
0.040
Why?
Oxidation-Reduction
1
2025
1078
0.040
Why?
Mice, Knockout
2
2025
3109
0.040
Why?
Lectins
2
1998
45
0.040
Why?
Interneurons
1
2022
125
0.040
Why?
Receptors, HIV
1
2000
23
0.040
Why?
Tissue Plasminogen Activator
1
2023
244
0.040
Why?
Neuroimaging
1
2023
293
0.040
Why?
Immune System
1
2022
178
0.040
Why?
DNA, Complementary
1
2021
273
0.040
Why?
Retina
1
2003
319
0.040
Why?
Insulin-Like Growth Factor I
1
2022
317
0.040
Why?
Double-Blind Method
1
2025
2033
0.040
Why?
Sensitivity and Specificity
1
2025
1995
0.040
Why?
Teratocarcinoma
1
2000
2
0.040
Why?
Phagocytosis
1
2021
296
0.040
Why?
Receptors, Dopamine D2
1
2000
93
0.040
Why?
Intracellular Space
1
2020
64
0.040
Why?
Organoids
1
2021
139
0.040
Why?
Acyclovir
1
2020
96
0.040
Why?
Extracellular Space
1
2020
119
0.040
Why?
Pilot Projects
1
2025
1886
0.040
Why?
Phytohemagglutinins
1
1999
29
0.040
Why?
Viral Envelope Proteins
1
2020
98
0.040
Why?
Cell Line
2
2022
2821
0.040
Why?
Cerebral Palsy
1
2021
137
0.040
Why?
Thrombosis
1
2023
396
0.040
Why?
DNA, Viral
1
2021
357
0.040
Why?
Nicotine
1
2021
334
0.040
Why?
Genotype
1
2004
1847
0.040
Why?
Reactive Oxygen Species
1
2021
601
0.040
Why?
Induced Pluripotent Stem Cells
1
2021
269
0.040
Why?
Biomarkers, Tumor
1
2025
1319
0.030
Why?
Receptors, G-Protein-Coupled
1
2000
231
0.030
Why?
Gene Expression Regulation, Neoplastic
1
2024
1437
0.030
Why?
RNA, Messenger
2
2011
2815
0.030
Why?
MicroRNAs
1
2024
689
0.030
Why?
Calcium Signaling
1
2000
243
0.030
Why?
Asialoglycoproteins
1
1997
2
0.030
Why?
Fetuins
1
1997
3
0.030
Why?
Cytidine Monophosphate N-Acetylneuraminic Acid
1
1997
3
0.030
Why?
Nervous System
1
1998
69
0.030
Why?
Protein Binding
1
2004
2243
0.030
Why?
alpha-Fetoproteins
1
1997
42
0.030
Why?
Homozygote
1
2017
200
0.030
Why?
Gene Dosage
1
2017
148
0.030
Why?
Tretinoin
1
1998
124
0.030
Why?
Chromosomes, Human, Pair 21
1
2017
42
0.030
Why?
Heterozygote
1
2017
313
0.030
Why?
Carbohydrate Conformation
1
1996
15
0.030
Why?
Glycoproteins
1
1998
353
0.030
Why?
Oligosaccharides
1
1996
60
0.030
Why?
Parietal Lobe
1
1996
60
0.030
Why?
Glutathione Reductase
1
2015
24
0.030
Why?
Peroxiredoxins
1
2015
26
0.030
Why?
Substrate Specificity
1
1996
392
0.030
Why?
Brain Stem
1
1996
97
0.030
Why?
Glutathione Transferase
1
2015
96
0.030
Why?
Fetus
1
2000
800
0.030
Why?
Adolescent
2
2025
22409
0.030
Why?
Nervous System Diseases
1
1998
285
0.030
Why?
Acetylation
1
2015
249
0.030
Why?
Aldehydes
1
2015
141
0.030
Why?
Focus Groups
1
2017
566
0.030
Why?
Oxidative Phosphorylation
1
2015
209
0.030
Why?
Academic Medical Centers
1
2017
545
0.030
Why?
Antiviral Agents
1
2020
765
0.030
Why?
Cerebellum
1
1996
224
0.030
Why?
Glutathione
1
2015
366
0.020
Why?
Superoxide Dismutase
1
2015
303
0.020
Why?
Cell Differentiation
2
1998
2037
0.020
Why?
Risk Assessment
1
2023
3729
0.020
Why?
Interviews as Topic
1
2017
905
0.020
Why?
Mice, Transgenic
1
2017
2184
0.020
Why?
Neoplasm Proteins
1
1995
441
0.020
Why?
Lipid Metabolism
1
2015
524
0.020
Why?
Risk Factors
1
2026
10796
0.020
Why?
SEC Translocation Channels
1
2011
9
0.020
Why?
Amino Acids
1
2015
521
0.020
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2011
94
0.020
Why?
Lung
1
2024
4089
0.020
Why?
Mutagenesis, Site-Directed
1
2011
374
0.020
Why?
Protein Stability
1
2011
177
0.020
Why?
Hydrophobic and Hydrophilic Interactions
1
2011
187
0.020
Why?
Child, Preschool
1
2025
11790
0.020
Why?
Genetic Vectors
1
2011
334
0.020
Why?
HeLa Cells
1
2011
632
0.020
Why?
Protein Transport
1
2011
437
0.020
Why?
Qualitative Research
1
2017
1668
0.020
Why?
RNA, Small Interfering
1
2011
631
0.020
Why?
Young Adult
1
2025
14122
0.020
Why?
Treatment Outcome
1
2023
11735
0.020
Why?
Promoter Regions, Genetic
1
2011
1246
0.020
Why?
Antineoplastic Agents
1
1998
2201
0.020
Why?
Child
1
2025
22600
0.010
Why?
Transcription, Genetic
1
2011
1468
0.010
Why?
Retrospective Studies
1
2022
17149
0.010
Why?
In Situ Nick-End Labeling
1
2003
120
0.010
Why?
Chick Embryo
1
2003
132
0.010
Why?
Glycogen Synthase Kinase 3 beta
1
2003
72
0.010
Why?
Glycogen Synthase Kinase 3
1
2003
81
0.010
Why?
Chemokine CXCL12
1
2003
86
0.010
Why?
Nerve Growth Factors
1
2003
78
0.010
Why?
Receptors, CXCR4
1
2003
91
0.010
Why?
Infant
1
2017
10023
0.010
Why?
Cell Count
1
2003
320
0.010
Why?
Cyclic AMP
1
2003
205
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2003
125
0.010
Why?
Mitogen-Activated Protein Kinases
1
2003
287
0.010
Why?
Apelin Receptors
1
2000
4
0.010
Why?
Dopamine D2 Receptor Antagonists
1
2000
5
0.010
Why?
Apelin
1
2000
10
0.010
Why?
Adipokines
1
2000
57
0.010
Why?
Receptors, Virus
1
2000
96
0.010
Why?
Simian Immunodeficiency Virus
1
2000
93
0.010
Why?
Cell Survival
1
2003
1092
0.010
Why?
Primates
1
2000
133
0.010
Why?
Swainsonine
1
1999
1
0.010
Why?
1-Deoxynojirimycin
1
1999
1
0.010
Why?
Mannosidases
1
1999
3
0.010
Why?
Neuraminidase
1
1999
25
0.010
Why?
Tissue Distribution
1
1999
335
0.010
Why?
Phosphorylation
1
2003
1704
0.010
Why?
Transfection
1
2000
924
0.010
Why?
Biological Transport
1
1999
418
0.010
Why?
Leukocytes, Mononuclear
1
2000
572
0.010
Why?
Mice, Inbred BALB C
1
2000
1251
0.010
Why?
Solubility
1
1998
236
0.010
Why?
Blotting, Western
1
1999
1161
0.010
Why?
Pituitary Neoplasms
1
1999
190
0.010
Why?
Carrier Proteins
1
2000
733
0.010
Why?
HIV-1
1
2000
897
0.010
Why?
Antibodies, Monoclonal
1
2000
1505
0.010
Why?
T-Lymphocytes
1
2000
1984
0.010
Why?
Coughlan's Networks
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