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Drew Scott Kern

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-NEUR General Operations

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Frassica M, Kern DS, Afshari M, Connolly AT, Wu C, Rowland N, Ramirez-Castaneda J, Ushe M, Salazar C, Mason X. Racial disparities in access to DBS: results of a real-world U.S. claims data analysis. Front Neurol. 2023; 14:1233684. PMID: 37602243.
      View in: PubMed
    2. Radcliffe EM, Baumgartner AJ, Kern DS, Al Borno M, Ojemann S, Kramer DR, Thompson JA. Oscillatory beta dynamics inform biomarker-driven treatment optimization for Parkinson's disease. J Neurophysiol. 2023 06 01; 129(6):1492-1504. PMID: 37198135.
      View in: PubMed
    3. Thompson JA, Hirt L, David-Gerecht P, Fasano A, Kramer DR, Ojemann SG, Kern DS. Comparison of Monopolar Review to Fixed Parameter Fractionation in Deep Brain Stimulation. Mov Disord Clin Pract. 2023 Jun; 10(6):987-991. PMID: 37332654.
      View in: PubMed
    4. Lewis S, Radcliffe E, Ojemann S, Kramer DR, Hirt L, Case M, Holt-Becker AB, Raike R, Kern DS, Thompson JA. Pilot Study to Investigate the Use of In-Clinic Sensing to Identify Optimal Stimulation Parameters for Deep Brain Stimulation Therapy in Parkinson's Disease. Neuromodulation. 2024 Apr; 27(3):509-519. PMID: 36797194.
      View in: PubMed
    5. Gibbons C, Wang N, Rajan S, Kern D, Palma JA, Kaufmann H, Freeman R. Cutaneous a-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease. Neurology. 2023 04 11; 100(15):e1529-e1539. PMID: 36657992.
      View in: PubMed
    6. McQueen RB, Gritz M, Kern D, Bemski JL, Shelton I, Meyer M, Kluger BM. Cost and Return on Investment of a Team-Based Palliative Care Program for Parkinson Disease. Neurol Clin Pract. 2022 Dec; 12(6):429-437. PMID: 36540151.
      View in: PubMed
    7. Marsili L, Keeling EG, Maciel R, Contarino MF, Zutt R, Okun MS, Almeida L, Deeb W, Kern D, Macias-Garcia D, Carrillo F, Mir P, Merola A, Espay AJ, Fasano A. Functional Movement Disorders and Deep Brain Stimulation: A Multi-Center Study. Mov Disord Clin Pract. 2023 Jan; 10(1):94-100. PMID: 36704077.
      View in: PubMed
    8. Tekriwal A, Baker S, Christensen E, Petersen-Jones H, Tien RN, Ojemann SG, Kern DS, Kramer DR, Felsen G, Thompson JA. Quantifying neuro-motor correlations during awake deep brain stimulation surgery using markerless tracking. Sci Rep. 2022 10 27; 12(1):18120. PMID: 36302865.
      View in: PubMed
    9. Baker S, Tekriwal A, Felsen G, Christensen E, Hirt L, Ojemann SG, Kramer DR, Kern DS, Thompson JA. Automatic extraction of upper-limb kinematic activity using deep learning-based markerless tracking during deep brain stimulation implantation for Parkinson's disease: A proof of concept study. PLoS One. 2022; 17(10):e0275490. PMID: 36264986.
      View in: PubMed
    10. Serva SN, Bernstein J, Thompson JA, Kern DS, Ojemann SG. An update on advanced therapies for Parkinson's disease: From gene therapy to neuromodulation. Front Surg. 2022; 9:863921. PMID: 36211256.
      View in: PubMed
    11. Kern D, Korsmo M, Baumgartner AJ, Kramer D, Ojemann S, Case M, Holt-Becker AB, Raike R, Thompson JA. Methylphenidate effects on a clinically informative oscillatory signal within the subthalamic nucleus in Parkinson's disease during deep brain stimulation programming. Brain Stimul. 2022 May-Jun; 15(3):747-749. PMID: 35526817.
      View in: PubMed
    12. Baumgartner AJ, Thompson JA, Kern DS, Ojemann SG. Novel targets in deep brain stimulation for movement disorders. Neurosurg Rev. 2022 Aug; 45(4):2593-2613. PMID: 35511309.
      View in: PubMed
    13. Bally JF, Kern DS, Fearon C, Camargos S, Pereira da Silva-Junior F, Barbosa ER, Ozelius LJ, de Carvalho Aguiar P, Lang AE. DYT-TUBB4A (DYT4 Dystonia): Clinical Anthology of 11 Cases and Systematized Review. Mov Disord Clin Pract. 2022 Jul; 9(5):659-675. PMID: 35844288.
      View in: PubMed
    14. Hirt L, Kern DS, Ojemann S, Grassia F, Kramer D, Thompson JA. Use of Three-Dimensional Printed Brain Models During Deep Brain Stimulation Surgery Consultation for Patient Health Literacy: A Randomized Controlled Investigation. World Neurosurg. 2022 06; 162:e526-e533. PMID: 35306197.
      View in: PubMed
    15. Fearon C, Rawal S, Olszewska D, Alcaide-Leon P, Kern DS, Sharma S, Jaiswal SK, Murthy JMK, Ha AD, Schwartz RS, Fung VSC, Spears C, Tholanikunnel T, Almeida L, Hatano T, Oji Y, Hattori N, Shubham S, Kumar H, Bhidayasiri R, Laohathai C, Lang AE. Neuroimaging Pearls from the MDS Congress Video Challenge. Part 2: Acquired Disorders. Mov Disord Clin Pract. 2022 Apr; 9(3):311-325. PMID: 35402651.
      View in: PubMed
    16. Hirt L, Grassia F, Feuerstein J, Thompson JA, Ojemann S, Kern DS. Deep Brain Stimulation of the Ventral Intermediate Nucleus of the Thalamus in Writer's Cramp: A Case Report. Tremor Other Hyperkinet Mov (N Y). 2021; 11:46. PMID: 34824889.
      View in: PubMed
    17. Baumgartner AJ, Kushida CA, Summers MO, Kern DS, Abosch A, Thompson JA. Basal Ganglia Local Field Potentials as a Potential Biomarker for Sleep Disturbance in Parkinson's Disease. Front Neurol. 2021; 12:765203. PMID: 34777232.
      View in: PubMed
    18. Thaker AA, Reddy KM, Thompson JA, Gerecht PD, Brown MS, Abosch A, Ojemann SG, Kern DS. Coronal Gradient Echo MRI to Visualize the Zona Incerta for Deep Brain Stimulation Targeting in Parkinson's Disease. Stereotact Funct Neurosurg. 2021; 99(5):443-450. PMID: 33902054.
      View in: PubMed
    19. Davis RA, Winston H, Gault JM, Kern DS, Mikulich-Gilbertson SK, Abosch A. Deep Brain Stimulation for OCD in a Patient With Comorbidities: Epilepsy, Tics, Autism, and Major Depressive Disorder. J Neuropsychiatry Clin Neurosci. 2021 Spring; 33(2):167-171. PMID: 33535803.
      View in: PubMed
    20. Kern DS, Fasano A, Thompson JA, Abosch A, Ojemann S, Munhoz RP. Constant Current versus Constant Voltage: Clinical Evidence Supporting a Fundamental Difference in the Modalities. Stereotact Funct Neurosurg. 2021; 99(2):171-175. PMID: 33227781.
      View in: PubMed
    21. Bally JF, Camargos S, Oliveira Dos Santos C, Kern DS, Lee T, Pereira da Silva-Junior F, Puga RD, Cardoso F, Barbosa ER, Yadav R, Ozelius LJ, de Carvalho Aguiar P, Lang AE. DYT-TUBB4A (DYT4 Dystonia): New Clinical and Genetic Observations. Neurology. 2021 04 06; 96(14):e1887-e1897. PMID: 32943487.
      View in: PubMed
    22. Kern DS, Uy D, Rhoades R, Ojemann S, Abosch A, Thompson JA. Discrete changes in brain volume after deep brain stimulation in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 2020 09; 91(9):928-937. PMID: 32651244.
      View in: PubMed
    23. Pang Y, Christenson J, Jiang F, Lei T, Rhoades R, Kern D, Thompson JA, Liu C. Automatic detection and quantification of hand movements toward development of an objective assessment of tremor and bradykinesia in Parkinson's disease. J Neurosci Methods. 2020 03 01; 333:108576. PMID: 31923452.
      View in: PubMed
    24. Deuel L, Collins AE, Maa EH, Barr JP, Kern DS. Dravet syndrome and parkinsonism: A case report investigating the dopaminergic system. Neurology. 2019 09 24; 93(13):595-596. PMID: 31444242.
      View in: PubMed
    25. Tekriwal A, Afshar NM, Santiago-Moreno J, Kuijper FM, Kern DS, Halpern CH, Felsen G, Thompson JA. Neural Circuit and Clinical Insights from Intraoperative Recordings During Deep Brain Stimulation Surgery. Brain Sci. 2019 Jul 20; 9(7). PMID: 31330813.
      View in: PubMed
    26. Kern DS, Picillo M, Thompson JA, Sammartino F, di Biase L, Munhoz RP, Fasano A. Interleaving Stimulation in Parkinson's Disease, Tremor, and Dystonia. Stereotact Funct Neurosurg. 2018; 96(6):379-391. PMID: 30654368.
      View in: PubMed
    27. Mestre TA, Pont-Sunyer C, Kausar F, Visanji NP, Ghate T, Connolly BS, Gasca-Salas C, Kern DS, Jain J, Slow EJ, Faust-Socher A, Kasten M, Wadia PM, Zadikoff C, Kumar P, de Bie RM, Thomsen T, Lang AE, Sch?le B, Klein C, Tolosa E, Marras C. Clustering of motor and nonmotor traits in leucine-rich repeat kinase 2 G2019S Parkinson's disease nonparkinsonian relatives: A multicenter family study. Mov Disord. 2018 Jul; 33(6):960-965. PMID: 29665080.
      View in: PubMed
    28. Arora S, Visanji NP, Mestre TA, Tsanas A, AlDakheel A, Connolly BS, Gasca-Salas C, Kern DS, Jain J, Slow EJ, Faust-Socher A, Lang AE, Little MA, Marras C. Investigating Voice as a Biomarker for Leucine-Rich Repeat Kinase 2-Associated Parkinson's Disease. J Parkinsons Dis. 2018; 8(4):503-510. PMID: 30248062.
      View in: PubMed
    29. van den Heuvel L, Lim AS, Visanji NP, Huang J, Ghate T, Mestre TA, AlDakheel A, Connolly BS, Gasca-Salas C, Kern DS, Jain J, Slow EJ, Pondal M, Faust-Socher A, Rogaeva E, Tomlinson G, Lang AE, Marras C. Actigraphy Detects Greater Intra-Individual Variability During Gait in Non-Manifesting LRRK2 Mutation Carriers. J Parkinsons Dis. 2018; 8(1):131-139. PMID: 29480219.
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    30. Fullard ME, Thibault DP, Todaro V, Foster S, Katz L, Morgan R, Kern DS, Schwalb JM, Urrea Mendoza E, Dahodwala N, Shulman L, Willis AW. Sex disparities in health and health care utilization after Parkinson diagnosis: Rethinking PD associated disability. Parkinsonism Relat Disord. 2018 03; 48:45-50. PMID: 29273434.
      View in: PubMed
    31. Fullard ME, Thibault DP, Hill A, Fox J, Bhatti DE, Burack MA, Dahodwala N, Haberfeld E, Kern DS, Klepitskava OS, Urrea-Mendoza E, Myers P, Nutt J, Rafferty MR, Schwalb JM, Shulman LM, Willis AW. Utilization of rehabilitation therapy services in Parkinson disease in the United States. Neurology. 2017 Sep 12; 89(11):1162-1169. PMID: 28835397.
      View in: PubMed
    32. Visanji NP, Bhudhikanok GS, Mestre TA, Ghate T, Udupa K, AlDakheel A, Connolly BS, Gasca-Salas C, Kern DS, Jain J, Slow EJ, Faust-Socher A, Kim S, Azhu Valappil R, Kausar F, Rogaeva E, William Langston J, Tanner CM, Sch?le B, Lang AE, Goldman SM, Marras C. Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease. Mov Disord. 2017 04; 32(4):610-614. PMID: 28071824.
      View in: PubMed
    33. Tekriwal A, Kern DS, Tsai J, Ince NF, Wu J, Thompson JA, Abosch A. REM sleep behaviour disorder: prodromal and mechanistic insights for Parkinson's disease. J Neurol Neurosurg Psychiatry. 2017 05; 88(5):445-451. PMID: 27965397.
      View in: PubMed
    34. Picillo M, Vincos GB, Kern DS, Fox SH, Lang AE, Fasano A. Learning More from Finger Tapping in Parkinson's Disease: Up and Down from Dyskinesia to Bradykinesia. Mov Disord Clin Pract. 2016 Mar-Apr; 3(2):184-187. PMID: 30713911.
      View in: PubMed
    35. Kern DS, Lang AE. Successful treatment of functional palatal tremor: Insights into pathogenesis and management. Mov Disord. 2015 May; 30(6):875-6. PMID: 25914234.
      View in: PubMed
    36. Visanji NP, Marras C, Kern DS, Al Dakheel A, Gao A, Liu LW, Lang AE, Hazrati LN. Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease. Neurology. 2015 Feb 10; 84(6):609-16. PMID: 25589666.
      View in: PubMed
    37. Lampe KJ, Kern DS, Mahoney MJ, Bjugstad KB. The administration of BDNF and GDNF to the brain via PLGA microparticles patterned within a degradable PEG-based hydrogel: Protein distribution and the glial response. J Biomed Mater Res A. 2011 Mar 01; 96(3):595-607. PMID: 21254391.
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    38. Bjugstad KB, Lampe K, Kern DS, Mahoney M. Biocompatibility of poly(ethylene glycol)-based hydrogels in the brain: an analysis of the glial response across space and time. J Biomed Mater Res A. 2010 Oct; 95(1):79-91. PMID: 20740603.
      View in: PubMed
    39. Kern DS, Maclean KN, Jiang H, Synder EY, Sladek JR, Bjugstad KB. Neural stem cells reduce hippocampal tau and reelin accumulation in aged Ts65Dn Down syndrome mice. Cell Transplant. 2011; 20(3):371-9. PMID: 20875225.
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    40. Bjugstad KB, Redmond DE, Lampe KJ, Kern DS, Sladek JR, Mahoney MJ. Biocompatibility of PEG-based hydrogels in primate brain. Cell Transplant. 2008; 17(4):409-15. PMID: 18522243.
      View in: PubMed
    41. Kern DS, Kumar R. Deep brain stimulation. Neurologist. 2007 Sep; 13(5):237-52. PMID: 17848864.
      View in: PubMed
    42. Kern DS, Semmler JG, Enoka RM. Long-term activity in upper- and lower-limb muscles of humans. J Appl Physiol (1985). 2001 Nov; 91(5):2224-32. PMID: 11641365.
      View in: PubMed
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