Plasmids
"Plasmids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
| Descriptor ID |
D010957
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| MeSH Number(s) |
G05.360.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Plasmids".
Below are MeSH descriptors whose meaning is more specific than "Plasmids".
This graph shows the total number of publications written about "Plasmids" by people in this website by year, and whether "Plasmids" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 5 | 5 | | 1997 | 0 | 6 | 6 | | 1998 | 1 | 1 | 2 | | 1999 | 2 | 1 | 3 | | 2000 | 2 | 11 | 13 | | 2001 | 0 | 9 | 9 | | 2002 | 3 | 14 | 17 | | 2003 | 1 | 11 | 12 | | 2004 | 2 | 18 | 20 | | 2005 | 1 | 12 | 13 | | 2006 | 1 | 10 | 11 | | 2007 | 0 | 9 | 9 | | 2008 | 2 | 13 | 15 | | 2009 | 2 | 11 | 13 | | 2010 | 1 | 6 | 7 | | 2011 | 2 | 11 | 13 | | 2012 | 0 | 9 | 9 | | 2013 | 1 | 6 | 7 | | 2014 | 2 | 4 | 6 | | 2015 | 0 | 2 | 2 | | 2016 | 1 | 3 | 4 | | 2017 | 1 | 2 | 3 | | 2018 | 0 | 5 | 5 | | 2019 | 0 | 2 | 2 | | 2020 | 3 | 3 | 6 | | 2021 | 0 | 4 | 4 | | 2022 | 0 | 3 | 3 | | 2023 | 1 | 4 | 5 | | 2024 | 3 | 1 | 4 | | 2025 | 1 | 1 | 2 | | 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "Plasmids" by people in Profiles.
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Greenbaum CJ, Long SA, Gitelman SE, Gaglia JL, Daniels M, Brusko TM, Lord S, Bundy BN, Krischer JP, Haller MJ, Steck AK, DiMeglio LA, Evans-Molina C, Moran A, Prahalad P, Wilson DM, Russell WE, Sherr JL, Raskin P, Clements MA, Moore WV, Libman I, Wassermann K, von Herrath M, Bergholdt R, Hastrup H, Kobernat SE, Kus AM, Tung LW, Goland RS, Herold KC. Phase I Clinical Trial of Islet Antigen-Specific Plasmid Coexpressing Tolerogenic Proteins Demonstrates Safety in Adults With Type 1 Diabetes. Diabetes. 2026 Mar 01; 75(3):506-518.
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Nagy TA, Gersabeck GW, Conte AN, Whiteley AT. A phage protein screen identifies triggers of the bacterial innate immune system. Nat Microbiol. 2026 Feb; 11(2):597-609.
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Nguyen A, Jenkins GM, Brones PD, Parrett GA, Hagen GM, Bono JM, Risser DD. A new family of bacterial actin-like proteins regulates cell morphology in a filamentous cyanobacterium. mSphere. 2025 Nov 25; 10(11):e0049925.
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Sekar RP, Lawson JL, McGrath C, Wheeler G, Moreau G, Johansen CG, Farnsworth NL, Kumar R. Tuning DLVO Interactions Alters Polymer-Mediated pDNA Delivery in a Cell Type-Dependent Manner. Langmuir. 2025 Jul 15; 41(27):17426-17438.
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Rafael Correia Rocha I, Finch MR, Ball JB, Harland ME, Clements M, Green-Fulgham S, Song G, Liu Y, Banov D, Watkins LR. An initial investigation of transcutaneous delivery of plasmid DNA encoding interleukin-10 for the treatment of psoriatic skin conditions. Brain Behav Immun. 2025 Jan; 123:903-913.
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Lawson JL, Sekar RP, Wright ARE, Wheeler G, Yanes J, Estridge J, Johansen CG, Farnsworth NL, Kumar P, Tay JW, Kumar R. The Spatial Distribution of Lipophilic Cations in Gradient Copolymers Regulates Polymer-pDNA Complexation, Polyplex Aggregation, and Intracellular pDNA Delivery. Biomacromolecules. 2024 10 14; 25(10):6855-6870.
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Bullen NP, Johnson CN, Andersen SE, Arya G, Marotta SR, Lee YJ, Weigele PR, Whitney JC, Duerkop BA. An enterococcal phage protein inhibits type IV restriction enzymes involved in antiphage defense. Nat Commun. 2024 Aug 13; 15(1):6955.
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Saunders SH, Ahmed AM. ORBIT for E. coli: kilobase-scale oligonucleotide recombineering at high throughput and high efficiency. Nucleic Acids Res. 2024 May 08; 52(8):e43.
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Delfosse K, Gerhardinger C, Rinn JL, Maass PG. High-throughput functional analysis of regulatory variants using a massively parallel reporter assay. STAR Protoc. 2023 12 15; 4(4):102731.
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Prazeres PHDM, Ferreira H, Costa PAC, da Silva W, Alves MT, Padilla M, Thatte A, Santos AK, Lobo AO, Sabino A, Del Puerto HL, Mitchell MJ, Guimaraes PPG. Delivery of Plasmid DNA by Ionizable Lipid Nanoparticles to Induce CAR Expression in T Cells. Int J Nanomedicine. 2023; 18:5891-5904.
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