 Receptors, Nicotinic
"Receptors, Nicotinic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.
| Descriptor ID |
D011978
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| MeSH Number(s) |
D12.776.157.530.400.400.100.500 D12.776.543.550.450.500.100.500 D12.776.543.585.400.500.100.500 D12.776.543.750.130.687 D12.776.543.750.720.360.550
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| Concept/Terms |
Receptors, Nicotinic- Receptors, Nicotinic
- Nicotinic Receptors
- Nicotinic Acetylcholine Receptors
- Acetylcholine Receptors, Nicotinic
- Receptors, Nicotinic Acetylcholine
- Nicotinic Acetylcholine Receptor
- Acetylcholine Receptor, Nicotinic
- Receptor, Nicotinic Acetylcholine
- Nicotinic Receptor
- Receptor, Nicotinic
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Below are MeSH descriptors whose meaning is more general than "Receptors, Nicotinic".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Nicotinic [D12.776.157.530.400.400.100.500]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, Nicotinic [D12.776.543.550.450.500.100.500]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Nicotinic [D12.776.543.585.400.500.100.500]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, Nicotinic [D12.776.543.750.130.687]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Nicotinic [D12.776.543.750.720.360.550]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Nicotinic".
This graph shows the total number of publications written about "Receptors, Nicotinic" by people in this website by year, and whether "Receptors, Nicotinic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 0 | 3 | | 1997 | 3 | 1 | 4 | | 1998 | 3 | 2 | 5 | | 1999 | 3 | 1 | 4 | | 2000 | 7 | 1 | 8 | | 2001 | 6 | 2 | 8 | | 2002 | 9 | 1 | 10 | | 2003 | 8 | 3 | 11 | | 2004 | 5 | 0 | 5 | | 2005 | 7 | 2 | 9 | | 2006 | 1 | 0 | 1 | | 2007 | 13 | 1 | 14 | | 2008 | 8 | 4 | 12 | | 2009 | 15 | 3 | 18 | | 2010 | 13 | 1 | 14 | | 2011 | 12 | 2 | 14 | | 2012 | 19 | 2 | 21 | | 2013 | 13 | 2 | 15 | | 2014 | 4 | 2 | 6 | | 2015 | 6 | 3 | 9 | | 2016 | 3 | 0 | 3 | | 2017 | 4 | 3 | 7 | | 2018 | 4 | 0 | 4 | | 2019 | 2 | 1 | 3 | | 2020 | 2 | 0 | 2 | | 2021 | 3 | 1 | 4 | | 2022 | 2 | 0 | 2 | | 2024 | 2 | 0 | 2 | | 2025 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Nicotinic" by people in Profiles.
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Johnson EC, Lai D, Balbona JV, Miller AP, Hatoum AS, Deak JD, Jennings M, Baranger DAA, Galimberti M, Sanichwankul K, Thorgeirsson T, Colbert SMC, Adhikari K, Docherty AR, Degenhardt L, Edwards T, Fox L, Giannelis A, Jeffries PW, Korhonen T, Morrison CL, Nunez YZ, Palviainen T, Su MH, Romero Villela PN, Wetherill L, Willoughby EA, Zellers SM, Bierut LJ, Buchwald J, Copeland WE, Corley RP, Friedman NP, Foroud TM, Gillespie NA, Gizer IR, Heath AC, Hickie IB, Kaprio J, Keller MC, Lee JJ, Lind P, Madden PA, Maes HHM, Martin NG, McGue M, Medland SE, Nelson EC, Pearson J, Porjesz B, Stallings MC, Vrieze S, Wilhelmson KC, Kranzler HR, Walters RK, Polimanti R, Malison R, Zhou H, Stefansson K, Sanchez-Roige S, Potenza M, Mutirangura A, Shotelersuk V, Kalayasiri R, Edenberg HJ, Gelernter J, Agrawal A. Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. Psychol Med. 2025 Aug 20; 55:e234.
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Lombardi AM, Griffioen M, Wong H, Milstead R, Borski C, Shiely E, Bower ME, Schmitt E, LaPlante L, Ehringer MA, Stitzel J, Hoeffer CA. AKT2 Modulates Astrocytic Nicotine Responses In Vivo. Glia. 2025 Oct; 73(10):2098-2129.
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Williams BM, Steed ND, Woolley JT, Moedl AA, Nelson CA, Jones GC, Burris MD, Arias HR, Kim OH, Jang EY, Hone AJ, McIntosh JM, Yorgason JT, Steffensen SC. Catharanthine Modulates Mesolimbic Dopamine Transmission and Nicotine Psychomotor Effects via Inhibition of a6-Nicotinic Receptors and Dopamine Transporters. ACS Chem Neurosci. 2024 05 01; 15(9):1738-1754.
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Akinola LS, Gonzales J, Buzzi B, Mathews HL, Papke RL, Stitzel JA, Damaj MI. Investigating the role of nicotinic acetylcholine receptors in menthol's effects in mice. Drug Alcohol Depend. 2024 Apr 01; 257:111262.
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Quijano Cardé NA, Shaw J, Carter C, Kim S, Stitzel JA, Venkatesh SK, Ramchandani VA, De Biasi M. Mutation of the a5 nicotinic acetylcholine receptor subunit increases ethanol and nicotine consumption in adolescence and impacts adult drug consumption. Neuropharmacology. 2022 09 15; 216:109170.
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Rahman MM, Basta T, Teng J, Lee M, Worrell BT, Stowell MHB, Hibbs RE. Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat Struct Mol Biol. 2022 04; 29(4):386-394.
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Routhier J, Pons S, Freidja ML, Dalstein V, Cutrona J, Jonquet A, Lalun N, Mérol JC, Lathrop M, Stitzel JA, Kervoaze G, Pichavant M, Gosset P, Tournier JM, Birembaut P, Dormoy V, Maskos U. An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions. Nat Commun. 2021 11 04; 12(1):6384.
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Buck JM, O'Neill HC, Stitzel JA. The Intergenerational Transmission of Developmental Nicotine Exposure-Induced Neurodevelopmental Disorder-Like Phenotypes is Modulated by the Chrna5 D397N Polymorphism in Adolescent Mice. Behav Genet. 2021 11; 51(6):665-684.
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Adjangba C, Border R, Romero Villela PN, Ehringer MA, Evans LM. Little Evidence of Modified Genetic Effect of rs16969968 on Heavy Smoking Based on Age of Onset of Smoking. Nicotine Tob Res. 2021 05 24; 23(6):1055-1063.
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Minguez-Viñas T, Nielsen BE, Shoemark DK, Gotti C, Sessions RB, Mulholland AJ, Bouzat C, Wonnacott S, Gallagher T, Bermudez I, Oliveira AS. A conserved arginine with non-conserved function is a key determinant of agonist selectivity in a7 nicotinic ACh receptors. Br J Pharmacol. 2021 04; 178(7):1651-1668.
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