Central Nervous System Viral Diseases
 
																	
																		 
																	
																		
																	 
																	
																		 
																	
																		
																	 
																	
																			
																					
	"Central Nervous System Viral Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				Viral infections of the brain, spinal cord, meninges, or perimeningeal spaces.
    
			 
			
				
				
					
						| Descriptor ID | 
										
							D020805
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						| MeSH Number(s) | 
						
							 C02.182 C10.228.228.245 
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						| Concept/Terms | 
						
							Central Nervous System Viral Diseases- Central Nervous System Viral Diseases
 - Viral Infections, Central Nervous System
 - Infections, CNS, Viral
 - Infections, Viral CNS
 - CNS Infection, Viral
 - CNS Infections, Viral
 - Infection, Viral CNS
 - Viral CNS Infection
 - Viral CNS Infections
 - Viral Diseases, Central Nervous System
 - Central Nervous System Viral Infections
 
  
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				Below are MeSH descriptors whose meaning is more general than "Central Nervous System Viral Diseases". 
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Central Nervous System Viral Diseases". 
				
			 
		 
	 
 
																				
																					
	
	
		
			
			
					
				This graph shows the total number of publications written about "Central Nervous System Viral Diseases" by people in this website by year, and whether "Central Nervous System Viral Diseases" was a major or minor topic of these publications.  
				
					 
                    To see the data from this visualization as text,  click here. 
				 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1999 | 1 | 0 | 1 |  | 2002 | 1 | 0 | 1 |  | 2004 | 2 | 0 | 2 |  | 2005 | 1 | 0 | 1 |  | 2006 | 1 | 0 | 1 |  | 2007 | 1 | 0 | 1 |  | 2009 | 1 | 0 | 1 |  | 2013 | 1 | 0 | 1 |  | 2018 | 3 | 1 | 4 |  | 2019 | 8 | 2 | 10 |  | 2020 | 2 | 1 | 3 |  | 2021 | 2 | 0 | 2 |  | 2022 | 1 | 1 | 2 |  | 2023 | 2 | 2 | 4 |  | 2024 | 2 | 0 | 2 |  | 2025 | 1 | 1 | 2 |  
 
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				Below are the most recent publications written about "Central Nervous System Viral Diseases" by people in Profiles. 
						
					
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Nguyen-Tran H, Butler M, Simmons D, Dominguez SR, Messacar K. Return of the Biennial Circulation of Enterovirus D68 in Colorado Children in 2024 Following the Large 2022 Outbreak. Viruses. 2025 05 05; 17(5). 
															
								 
							
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Rudy MJ, Wilson CJ, Hinckley B, Baker DC, Royal JM, Hoke MP, Brennan MB, Vogt MR, Clarke P, Tyler KL. EV68-228-N monoclonal antibody treatment halts progression of paralysis in a mouse model of EV-D68 induced acute flaccid myelitis. mBio. 2025 Apr 09; 16(4):e0390624. 
															
								 
							
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Leser JS, Frost JL, Wilson CJ, Rudy MJ, Clarke P, Tyler KL. VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis. J Virol. 2024 Jul 23; 98(7):e0039724. 
															
								 
							
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Messacar K, Matzinger S, Berg K, Weisbeck K, Butler M, Pysnack N, Nguyen-Tran H, Davizon ES, Bankers L, Jung SA, Birkholz M, Wheeler A, Dominguez SR. Multimodal Surveillance Model for Enterovirus D68 Respiratory Disease and Acute Flaccid Myelitis among Children in Colorado, USA, 2022. Emerg Infect Dis. 2024 Mar; 30(3):423-431. 
															
								 
							
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Park SW, Messacar K, Douek DC, Spaulding AB, Metcalf CJE, Grenfell BT. Predicting the impact of COVID-19 non-pharmaceutical intervention on short- and medium-term dynamics of enterovirus D68 in the US. Epidemics. 2024 Mar; 46:100736. 
															
								 
							
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Nguyen-Tran H, Thompson C, Butler M, Miller KR, Pyle L, Jung S, Rogers S, Ng TFF, Routh J, Dominguez SR, Messacar K. Duration of Enterovirus D68 RNA Shedding in the Upper Respiratory Tract and Transmission among Household Contacts, Colorado, USA. Emerg Infect Dis. 2023 11; 29(11):2315-2324. 
															
								 
							
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Lane TR, Fu J, Sherry B, Tarbet B, Hurst BL, Riabova O, Kazakova E, Egorova A, Clarke P, Leser JS, Frost J, Rudy M, Tyler KL, Klose T, Volobueva AS, Belyaevskaya SV, Zarubaev VV, Kuhn RJ, Makarov V, Ekins S. Efficacy of an isoxazole-3-carboxamide analog of pleconaril in mouse models of Enterovirus-D68 and Coxsackie B5. Antiviral Res. 2023 08; 216:105654. 
															
								 
							
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Frost J, Rudy MJ, Leser JS, Tan H, Hu Y, Wang J, Clarke P, Tyler KL. Telaprevir Treatment Reduces Paralysis in a Mouse Model of Enterovirus D68 Acute Flaccid Myelitis. J Virol. 2023 05 31; 97(5):e0015623. 
															
								 
							
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Rudy MJ, Frost J, Clarke P, Tyler KL. Neutralizing Antibody Given after Paralysis Onset Reduces the Severity of Paralysis Compared to Nonspecific Antibody-Treated Controls in a Mouse Model of EV-D68-Associated Acute Flaccid Myelitis. Antimicrob Agents Chemother. 2022 08 16; 66(8):e0022722. 
															
								 
							
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Rudy MJ, Coughlan C, Hixon AM, Clarke P, Tyler KL. Density Analysis of Enterovirus D68 Shows Viral Particles Can Associate with Exosomes. Microbiol Spectr. 2022 02 23; 10(1):e0245221. 
															
								 
							
				 	
			 	
			
			
		 
	 
 
       
																				
                                                                            
																		
																	 
																 
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