 Chemokine CXCL12
"Chemokine CXCL12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing.
| Descriptor ID |
D054377
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| MeSH Number(s) |
D12.644.276.374.200.120.600 D12.776.467.374.200.120.600 D23.125.300.120.600 D23.469.200.120.600 D23.529.374.200.120.600
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| Concept/Terms |
Chemokine CXCL12- Chemokine CXCL12
- CXCL12, Chemokine
- Stromal Cell-Derived Factor 1
- Stromal Cell Derived Factor 1
- CXCL12 Chemokine
- Chemokine, CXCL12
- Chemokine (C-X-C Motif) Ligand 12
- Pre-B-Cell Growth-Stimulating Factor
- Growth-Stimulating Factor, Pre-B-Cell
- Pre B Cell Growth Stimulating Factor
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Below are MeSH descriptors whose meaning is more general than "Chemokine CXCL12".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CXCL12".
This graph shows the total number of publications written about "Chemokine CXCL12" by people in this website by year, and whether "Chemokine CXCL12" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 4 | 4 | | 2007 | 0 | 3 | 3 | | 2008 | 2 | 1 | 3 | | 2009 | 0 | 1 | 1 | | 2010 | 2 | 3 | 5 | | 2011 | 3 | 3 | 6 | | 2012 | 3 | 2 | 5 | | 2013 | 3 | 3 | 6 | | 2014 | 2 | 0 | 2 | | 2015 | 1 | 2 | 3 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 2 | 2 | | 2019 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chemokine CXCL12" by people in Profiles.
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Peddibhotla S, Caples K, Mehta A, Chen QY, Hu J, Idlett-Ali S, Zhang L, Zgheib C, Xu J, Liechty KW, Malany S. Triazolothiadiazine derivative positively modulates CXCR4 signaling and improves diabetic wound healing. Biochem Pharmacol. 2023 10; 216:115764.
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Xu J, Hu J, Idlett-Ali S, Zhang L, Caples K, Peddibhotla S, Reeves M, Zgheib C, Malany S, Liechty KW. Discovery of Small Molecule Activators of Chemokine Receptor CXCR4 That Improve Diabetic Wound Healing. Int J Mol Sci. 2022 Feb 16; 23(4).
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Martin AR, Patel JM, Locke RC, Eby MR, Saleh KS, Davidson MD, Sennett ML, Zlotnick HM, Chang AH, Carey JL, Burdick JA, Mauck RL. Nanofibrous hyaluronic acid scaffolds delivering TGF-?3 and SDF-1a for articular cartilage repair in a large animal model. Acta Biomater. 2021 05; 126:170-182.
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Hashimoto R, Lanier GM, Dhagia V, Joshi SR, Jordan A, Waddell I, Tuder R, Stenmark KR, Wolin MS, McMurtry IF, Gupte SA. Pluripotent hematopoietic stem cells augment a-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2020 02 01; 318(2):L386-L401.
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LaRocca TJ, Altman P, Jarrah AA, Gordon R, Wang E, Hadri L, Burke MW, Haddad GE, Hajjar RJ, Tarzami ST. CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy. Int J Mol Sci. 2019 May 08; 20(9).
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Bhagwani AR, Hultman S, Farkas D, Moncayo R, Dandamudi K, Zadu AK, Cool CD, Farkas L. Endothelial cells are a source of Nestin expression in Pulmonary Arterial Hypertension. PLoS One. 2019; 14(3):e0213890.
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Sterner RM, Kremer KN, Dudakovic A, Westendorf JJ, van Wijnen AJ, Hedin KE. Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis. J Immunol. 2018 08 01; 201(3):1086-1096.
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Barwinska D, Oueini H, Poirier C, Albrecht ME, Bogatcheva NV, Justice MJ, Saliba J, Schweitzer KS, Broxmeyer HE, March KL, Petrache I. AMD3100 ameliorates cigarette smoke-induced emphysema-like manifestations in mice. Am J Physiol Lung Cell Mol Physiol. 2018 09 01; 315(3):L382-L386.
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Jarrah AA, Schwarskopf M, Wang ER, LaRocca T, Dhume A, Zhang S, Hadri L, Hajjar RJ, Schecter AD, Tarzami ST. SDF-1 induces TNF-mediated apoptosis in cardiac myocytes. Apoptosis. 2018 01; 23(1):79-91.
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McClendon J, Jansing NL, Redente EF, Gandjeva A, Ito Y, Colgan SP, Ahmad A, Riches DWH, Chapman HA, Mason RJ, Tuder RM, Zemans RL. Hypoxia-Inducible Factor 1a Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury. Am J Pathol. 2017 Aug; 187(8):1772-1786.
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