 Amyloid
"Amyloid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.
| Descriptor ID |
D000682
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| MeSH Number(s) |
D05.500.049 D12.776.049
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| Concept/Terms |
Amyloid- Amyloid
- Amyloid Substance
- Substance, Amyloid
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Below are MeSH descriptors whose meaning is more general than "Amyloid".
Below are MeSH descriptors whose meaning is more specific than "Amyloid".
This graph shows the total number of publications written about "Amyloid" by people in this website by year, and whether "Amyloid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 2 | 0 | 2 | | 2002 | 2 | 1 | 3 | | 2003 | 1 | 0 | 1 | | 2004 | 3 | 0 | 3 | | 2006 | 5 | 1 | 6 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 3 | 0 | 3 | | 2010 | 2 | 1 | 3 | | 2011 | 4 | 1 | 5 | | 2012 | 1 | 2 | 3 | | 2013 | 3 | 3 | 6 | | 2014 | 2 | 0 | 2 | | 2015 | 2 | 0 | 2 | | 2016 | 3 | 2 | 5 | | 2017 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 | | 2019 | 3 | 2 | 5 | | 2020 | 4 | 3 | 7 | | 2021 | 3 | 3 | 6 | | 2022 | 1 | 5 | 6 | | 2023 | 1 | 2 | 3 | | 2024 | 0 | 2 | 2 | | 2025 | 3 | 0 | 3 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amyloid" by people in Profiles.
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Bassett PT, Nguyen BA, Singh V, Garrett PT, Moresco JJ, Eddy J, Afrin S, Pekala M, Lopez C, Evers BM, Ahmed Y, Pedretti R, Grodin JL, Roth LR, Kaur G, Chung S, Morgan GJ, Yates JR, Saelices L. Polymorphic IGLV6-57 AL amyloid fibrils and features of a shared folding pathway. Nat Commun. 2026 Jul 23; 17(1).
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Ledvina HE, Sayegh R, Carale RO, Burroughs AM, Macklin AR, Azadeh AL, Borja Najera LD, Aravind L, Whiteley AT. Functional amyloid proteins confer defence against predatory bacteria. Nature. 2025 08; 644(8075):197-204.
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Rech MA, Carpenter CR, Aggarwal NT, Hwang U. Anti-Amyloid Therapies for Alzheimer's Disease and Amyloid-Related Imaging Abnormalities: Implications for the Emergency Medicine Clinician. Ann Emerg Med. 2025 06; 85(6):526-536.
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Cogswell PM, Andrews TJ, Barakos JA, Barkhof F, Bash S, Benayoun MD, Chiang GC, Franceschi AM, Jack CR, Pillai JJ, Poussaint TY, Raji CA, Ramanan VK, Tanabe J, Tanenbaum L, Whitlow CT, Yu FF, Zaharchuk G, Zeinah M, Benzinger TS. Alzheimer Disease Anti-Amyloid Immunotherapies: Imaging Recommendations and Practice Considerations for Monitoring of Amyloid-Related Imaging Abnormalities. AJNR Am J Neuroradiol. 2025 Jan 08; 46(1):24-32.
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Vugmeyster L, Au DF, Frazier B, Qiang W, Ostrovsky D. Rigidifying of the internal dynamics of amyloid-beta fibrils generated in the presence of synaptic plasma vesicles. Phys Chem Chem Phys. 2024 Feb 07; 26(6):5466-5478.
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Kehrer-Dunlap A, Bollinger R, Chen SW, Keleman A, Thompson R, Fagan A, Ances B, Stark S. Higher amyloid is associated with greater loneliness among cognitively normal older adults during the COVID-19 pandemic. F1000Res. 2022; 11:1134.
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Sallaberry CA, Voss BJ, Stone WB, Estrada F, Bhatia A, Soto JD, Griffin CW, Vander Zanden CM. Curcumin Reduces Amyloid Beta Oligomer Interactions with Anionic Membranes. ACS Chem Neurosci. 2023 11 15; 14(22):4026-4038.
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Raju RP, Cai L, Tyagi A, Pugazhenthi S. Interactions of Cellular Energetic Gene Clusters in the Alzheimer's Mouse Brain. Mol Neurobiol. 2024 Jan; 61(1):476-486.
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Cruceta L, Sun Y, Kenyaga JM, Ostrovsky D, Rodgers A, Vugmeyster L, Yao L, Qiang W. Modulation of aggregation and structural polymorphisms of ß-amyloid fibrils in cellular environments by pyroglutamate-3 variant cross-seeding. J Biol Chem. 2023 10; 299(10):105196.
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Tyagi A, Musa M, Labeikovsky W, Pugazhenthi S. Sirt3 deficiency induced down regulation of insulin degrading enzyme in comorbid Alzheimer's disease with metabolic syndrome. Sci Rep. 2022 11 17; 12(1):19808.
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