 Amyloid
"Amyloid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.
| Descriptor ID |
D000682
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| MeSH Number(s) |
D05.500.049 D12.776.049
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| Concept/Terms |
Amyloid- Amyloid
- Amyloid Substance
- Substance, Amyloid
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Below are MeSH descriptors whose meaning is more general than "Amyloid".
Below are MeSH descriptors whose meaning is more specific than "Amyloid".
This graph shows the total number of publications written about "Amyloid" by people in this website by year, and whether "Amyloid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 | | 2001 | 2 | 0 | 2 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 3 | 0 | 3 | | 2006 | 4 | 1 | 5 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 1 | 3 | | 2012 | 1 | 2 | 3 | | 2013 | 2 | 2 | 4 | | 2014 | 4 | 1 | 5 | | 2015 | 2 | 0 | 2 | | 2016 | 3 | 2 | 5 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 3 | 1 | 4 | | 2020 | 3 | 4 | 7 | | 2021 | 3 | 3 | 6 | | 2022 | 1 | 5 | 6 | | 2023 | 0 | 2 | 2 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amyloid" by people in Profiles.
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Vugmeyster L, Au DF, Frazier B, Qiang W, Ostrovsky D. Rigidifying of the internal dynamics of amyloid-beta fibrils generated in the presence of synaptic plasma vesicles. Phys Chem Chem Phys. 2024 Feb 07; 26(6):5466-5478.
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Sallaberry CA, Voss BJ, Stone WB, Estrada F, Bhatia A, Soto JD, Griffin CW, Vander Zanden CM. Curcumin Reduces Amyloid Beta Oligomer Interactions with Anionic Membranes. ACS Chem Neurosci. 2023 11 15; 14(22):4026-4038.
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Raju RP, Cai L, Tyagi A, Pugazhenthi S. Interactions of Cellular Energetic Gene Clusters in the Alzheimer's Mouse Brain. Mol Neurobiol. 2024 Jan; 61(1):476-486.
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Tyagi A, Musa M, Labeikovsky W, Pugazhenthi S. Sirt3 deficiency induced down regulation of insulin degrading enzyme in comorbid Alzheimer's disease with metabolic syndrome. Sci Rep. 2022 11 17; 12(1):19808.
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Reichelderfer VT, Chaparro Sosa AF, Kaar JL, Schwartz DK. Tuning the surface charge of phospholipid bilayers inhibits insulin fibrilization. Colloids Surf B Biointerfaces. 2022 Dec; 220:112904.
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Ahmed J, Fitch TC, Donnelly CM, Joseph JA, Ball TD, Bassil MM, Son A, Zhang C, Ledreux A, Horowitz S, Qin Y, Paredes D, Kumar S. Foldamers reveal and validate therapeutic targets associated with toxic a-synuclein self-assembly. Nat Commun. 2022 04 27; 13(1):2273.
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Spatharas PM, Nasi GI, Tsiolaki PL, Theodoropoulou MK, Papandreou NC, Hoenger A, Trougakos IP, Iconomidou VA. Clusterin in Alzheimer's disease: An amyloidogenic inhibitor of amyloid formation? Biochim Biophys Acta Mol Basis Dis. 2022 07 01; 1868(7):166384.
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Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP. Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell. 2022 04 14; 185(8):1346-1355.e15.
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Vugmeyster L, Ostrovsky D, Greenwood A, Fu R. Deuteron rotating frame relaxation for the detection of slow motions in rotating solids. J Magn Reson. 2022 04; 337:107171.
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Vugmeyster L, Fai Au D, Smith MC, Ostrovsky D. Comparative Hydrophobic Core Dynamics Between Wild-Type Amyloid-? Fibrils, Glutamate-3 Truncation, and Serine-8 Phosphorylation. Chemphyschem. 2022 02 04; 23(3):e202100709.
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