Multiple Sclerosis
"Multiple Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Descriptor ID |
D009103
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| MeSH Number(s) |
C10.114.375.500 C10.314.350.500 C20.111.258.250.500
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| Concept/Terms |
Multiple Sclerosis- Multiple Sclerosis
- Sclerosis, Multiple
- Sclerosis, Disseminated
- Disseminated Sclerosis
- MS (Multiple Sclerosis)
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Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".
This graph shows the total number of publications written about "Multiple Sclerosis" by people in this website by year, and whether "Multiple Sclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 2000 | 2 | 0 | 2 | | 2001 | 3 | 0 | 3 | | 2002 | 1 | 1 | 2 | | 2003 | 6 | 0 | 6 | | 2004 | 2 | 1 | 3 | | 2005 | 9 | 0 | 9 | | 2006 | 8 | 1 | 9 | | 2007 | 7 | 1 | 8 | | 2008 | 6 | 1 | 7 | | 2009 | 8 | 1 | 9 | | 2010 | 8 | 0 | 8 | | 2011 | 8 | 2 | 10 | | 2012 | 6 | 2 | 8 | | 2013 | 5 | 3 | 8 | | 2014 | 9 | 1 | 10 | | 2015 | 8 | 0 | 8 | | 2016 | 9 | 4 | 13 | | 2017 | 23 | 3 | 26 | | 2018 | 18 | 1 | 19 | | 2019 | 17 | 1 | 18 | | 2020 | 18 | 2 | 20 | | 2021 | 18 | 2 | 20 | | 2022 | 23 | 1 | 24 | | 2023 | 38 | 0 | 38 | | 2024 | 23 | 2 | 25 | | 2025 | 18 | 1 | 19 | | 2026 | 11 | 3 | 14 |
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Below are the most recent publications written about "Multiple Sclerosis" by people in Profiles.
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Cooney LA, Lim N, Harris KM, Smilek DE, Bathala P, Stengelin M, Sigal G, Wohlstadter JN, Cencioni MT, Fernández Velasco JI, Mao-Draayer Y, Fox DA, Griffith LM, Nash R, Villar LM, Muraro PA. Autologous Hematopoietic Transplantation Reduces Brain Inflammatory and Axoglial Damage Biomarkers in Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2026 Nov; 13(6):e200653.
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Wong HK, Ho S, Yu Q, Given KS, Shqau D, Baier S, Winklmeier S, Rübsamen H, Kendirli A, Schanda K, Oswald E, Bräuer K, Thaler FS, Gerdes LA, Feederle R, Kerschensteiner M, Reindl M, Khademi M, Piehl F, Olsson T, Bennett JL, Kümpfel T, Kawakami N, Bradl M, Meinl E, Mader S. Antibodies against MLC1 found in patients with NMOSD-like disease mediate astrocytopathy in rodent models. Sci Transl Med. 2026 Aug 26; 18(864):eady0403.
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Hibner BA, Lima NS, Sherman SR, Motl RW, Chirinos JA, Phillips S, Clifford PS, Reder AT, Baynard T, Fernhall B. Ventricular-vascular coupling at rest and immediately following maximal exercise in adults with and without multiple sclerosis. Physiol Rep. 2026 Aug; 14(15):e71044.
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Scharf A, Cohen JA, Marrie RA, Miller AE, Waubant E, Kilbane M, Luskin E, Azevedo CJ, Dever M, Alvarez E, Calabresi PA, Chahin S, Freeman L, Nakamura K, Longbrake EE, Mowry EM, Oh J, Rodrigues PR, Ramos M, Sotirchos ES, Cutter GR, Kaisey M, Amin M, Toljan K, Illenberger N, Bilello M, Lee J, Maya M, Obusez EC, Schindler MK, Suthiphosuwan S, Ulano A, Shinohara RT, Reich DS, Solomon AJ, Sicotte NL, Sati P, Ontaneda D. Application of the 2024 McDonald Criteria in Individuals With Nonspecific Symptoms or Incidental Imaging Findings in a Multicenter Study. Neurology. 2026 Jul 14; 107(1):e218183.
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Tallantyre EC, Planchon SM, Howard H, Mays J, Frowd N, Cohen JA, Coles A, Hersh CM, Miller DM, Dever M, Gray EH, LaRocca NG, Nakamura K, Bale C, Covey-Crump G, Alvarez E, Arun T, Brownlee WJ, Craner M, Freeman L, Frost N, Goldman MD, Gupta RK, Harding KE, Hobart J, Hutton GJ, Hyland MH, Kalra S, Kannan M, Kantarci O, Lashley D, Lily O, Mahad D, Nicholas JA, Nicholas R, Paling D, Pearson OR, Rice CM, Samudralwar R, Schmalstieg WF, Singh M, Zune The E, Weinstock-Guttman B, Zabeti A, Love TE, Gunzler DD, Liu Y, Gerry S, Evangelou N, Ontaneda D. Disease-modifying treatment preferences and decision-making in a multiple sclerosis randomized and observational clinical trial (DELIVER-MS). Mult Scler. 2026 Jun; 32(7):722-736.
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Martell SG, Holthaus TA, Verma S, Adamson B, Motl RW, Khan NA. Mediterranean-DASH intervention for neurodegenerative delay (MIND) diet intervention in persons with multiple sclerosis: A feasibility, randomized controlled trial. Nutr Res. 2026 Aug; 152:11-25.
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Van Laethem D, Costers L, Miravalle A, Alvarez E, Myers B, Boster A, Al Halawani H, Dewil M, Cambron M, Grothe M, Denissen S, Bartz R, Sima D, Ribbens A, Smeets D, Nagels G. The relationship between objective and subjective cognitive performance and clinical and MRI disease burden in early multiple sclerosis. Sci Rep. 2026 May 16; 16(1).
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Apeltsin L, Asokan S, Freitas B, Karekar K, Guzman S, Alvarez E, Yu X. Multiplex Detection of Immunoglobulins Uncovers Intrathecal IgA Elevation in Multiple Sclerosis. Cells. 2026 May 10; 15(10).
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Hamdy E, Talaat F, Ramadan I, Oertel FC, Bennett JL, Abousteit A, Almashad SS, Zeineddine M, Hassan A, Said SM, Carnero Contentti E, Gaber D, Zakaria M, Ahmed S, Grigoriadis N, Fouda BH, Shalaby NM, Nasr N, Paul F, Zamzam D, Krupp L, Sayed A, Hassan SS, Naseer MA, Hegazy MI, Galeel AA, Elmesnshawy I, Salama S. Development and expert refinement of a stratified framework for progression independent of relapse activity (PIRA) in multiple sclerosis. Clin Neurol Neurosurg. 2026 Aug; 267:109430.
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Vasilenko N, Ruschil C, Stadelmaier J, Tieck MP, Schembecker S, Owens GP, Bennett JL, Berthele A, Ziemann U, Poli S, Snaidero N, Nahnsen S, Jarboui MA, Bichmann L, Gabernet G, Kowarik MC. Extensive peripheral immunoglobulin repertoire analyses in people with multiple sclerosis reveal disease-specific signatures and distinct treatment effects of disease modifying drugs. J Neuroinflammation. 2026 Apr 14; 23(1).
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