 Multiple Sclerosis
"Multiple Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Descriptor ID |
D009103
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| MeSH Number(s) |
C10.114.375.500 C10.314.350.500 C20.111.258.250.500
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| Concept/Terms |
Multiple Sclerosis- Multiple Sclerosis
- Sclerosis, Multiple
- Sclerosis, Disseminated
- Disseminated Sclerosis
- MS (Multiple Sclerosis)
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Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".
This graph shows the total number of publications written about "Multiple Sclerosis" by people in this website by year, and whether "Multiple Sclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 2000 | 2 | 0 | 2 | | 2001 | 3 | 0 | 3 | | 2002 | 1 | 1 | 2 | | 2003 | 6 | 0 | 6 | | 2004 | 2 | 1 | 3 | | 2005 | 8 | 0 | 8 | | 2006 | 7 | 1 | 8 | | 2007 | 7 | 1 | 8 | | 2008 | 6 | 1 | 7 | | 2009 | 8 | 0 | 8 | | 2010 | 8 | 0 | 8 | | 2011 | 8 | 2 | 10 | | 2012 | 6 | 2 | 8 | | 2013 | 5 | 3 | 8 | | 2014 | 9 | 1 | 10 | | 2015 | 8 | 0 | 8 | | 2016 | 10 | 3 | 13 | | 2017 | 23 | 3 | 26 | | 2018 | 18 | 0 | 18 | | 2019 | 18 | 2 | 20 | | 2020 | 18 | 2 | 20 | | 2021 | 19 | 2 | 21 | | 2022 | 24 | 1 | 25 | | 2023 | 38 | 0 | 38 | | 2024 | 24 | 2 | 26 | | 2025 | 16 | 1 | 17 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Multiple Sclerosis" by people in Profiles.
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Henry M, Crompton T, Alvarez E, Enoka RM. Impaired force control and muscle activation during isometric contractions in people with multiple sclerosis. J Electromyogr Kinesiol. 2026 Apr; 87:103124.
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Marrie RA, Dobson R, Baranzini SE, Salvetti M, Bailey C, Bebo B, Davis B, Greenland R, Lyden J, Mckay F, Morahan J, Petrin J, Valentine P, Taylor B. Toward a global research agenda for preventing multiple sclerosis. Mult Scler. 2026 Feb; 32(2):151-162.
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Sherman SR, Lima NS, Motl RW, Reder AT, Baynard T, Fernhall B, Hibner BA. Impaired inactive limb blood flow regulation in adults with multiple sclerosis during sympathoexcitatory stimuli. Physiol Rep. 2025 Dec; 13(23):e70694.
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Yang JH, Race J, Sumowski P, Jacques K, Fardad S, Fair A, Hazlett A, Lin J, Yilmaz D, Aaen G, Abrams A, Benson L, Casper TC, Chitnis T, Gorman M, Lotze T, Krupp L, Mar S, Ness J, Rensel M, Rose J, Schreiner T, Tillema JM, Waldman A, Wheeler Y, Barcellos LF, Waubant E, Graves JS. Epigenetic age and telomere length correlations in pediatric-onset multiple sclerosis. Mult Scler. 2025 Dec; 31(14):1641-1650.
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Ghezzi L, Kosa P, Greenwood M, Alvarez E, Freedman CL, Cross AH, Pace F, Freedman MS, Kocot J, Piccio L, Bielekova B. From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis. Ann Neurol. 2026 Feb; 99(2):328-340.
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O'Neill KA, Charvet L, Waltz M, George A, Benson LA, Gorman MP, Mar SS, Ness JM, Schreiner T, Waubant E, Weinstock-Guttman B, Wheeler YS, Abrams AW, Chitnis T, Rodriguez M, Rose JW, Tillema JM, Virupakshaiah A, Casper TC, Krupp LB. Cognitive Function in People With Pediatric Multiple Sclerosis Over 2 Years. Neurology. 2025 Oct 21; 105(8):e214142.
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Wright MA, Barney BJ, Peterson S, Waltz M, Rose J, Rensel M, Abrams A, Waubant E, Wheeler Y, Rodriguez M, Tillema JM, Krupp L, Gorman M, Benson L, Lotze T, Shukla N, Mar S, Chitnis T, Schreiner T, Vignos M, Casper TC. Evaluating Efficacy Outcomes in Pediatric Multiple Sclerosis Patients While Using Avonex or Plegridy via USNPMSC Registry. J Child Neurol. 2026 Apr; 41(4):545-555.
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Goyne C, Fair AE, Yilmaz D, Race J, Schuette A, Caillier SJ, Aaen GS, Abrams AW, Benson LA, Casper TC, Chitnis T, Gorman MP, Lotze TE, Krupp LB, Mar SS, Ness JM, Rensel M, Rodriguez M, Rose JW, Schreiner TL, Tillema JM, Waldman AT, Wheeler YS, Barcellos LF, Waubant E, Graves JS. Epigenetic Aging in Pediatric-Onset Multiple Sclerosis. Neurology. 2025 Jun 24; 104(12):e213673.
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O'Neill KA, Charvet L, George A, Waltz M, Casper TC, Benson L, Gorman M, Mar S, Ness J, Schreiner T, Waubant E, Weinstock-Guttman B, Wheeler Y, Ortiz R, Krupp LB. Childhood adversity in parents of patients with pediatric multiple sclerosis. Mult Scler Relat Disord. 2025 Jun; 98:106424.
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Williams J, Marin WM, Wade KJ, Suseno R, Kizer K, Caillier S, Augusto DG, Norman PJ, Hollenbach JA. Copy number variation at the complement C4 locus is associated with risk for multiple sclerosis. Mult Scler. 2025 Sep; 31(10):1243-1246.
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