 Brain-Derived Neurotrophic Factor
"Brain-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)
| Descriptor ID |
D019208
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| MeSH Number(s) |
D12.644.276.860.100 D12.776.467.860.100 D12.776.631.600.100 D23.529.850.100
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| Concept/Terms |
Brain-Derived Neurotrophic Factor- Brain-Derived Neurotrophic Factor
- Brain Derived Neurotrophic Factor
- Factor, Brain-Derived Neurotrophic
- Neurotrophic Factor, Brain-Derived
- BDNF
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Below are MeSH descriptors whose meaning is more general than "Brain-Derived Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Brain-Derived Neurotrophic Factor".
This graph shows the total number of publications written about "Brain-Derived Neurotrophic Factor" by people in this website by year, and whether "Brain-Derived Neurotrophic Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1999 | 1 | 1 | 2 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 0 | 2 | | 2004 | 1 | 0 | 1 | | 2005 | 3 | 3 | 6 | | 2006 | 2 | 1 | 3 | | 2007 | 4 | 1 | 5 | | 2008 | 3 | 1 | 4 | | 2009 | 1 | 1 | 2 | | 2010 | 3 | 0 | 3 | | 2011 | 4 | 2 | 6 | | 2012 | 2 | 1 | 3 | | 2013 | 1 | 3 | 4 | | 2014 | 3 | 5 | 8 | | 2015 | 8 | 2 | 10 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 3 | 4 | | 2018 | 2 | 2 | 4 | | 2019 | 5 | 3 | 8 | | 2020 | 0 | 3 | 3 | | 2021 | 2 | 2 | 4 | | 2022 | 0 | 1 | 1 | | 2023 | 1 | 0 | 1 | | 2025 | 2 | 3 | 5 |
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Below are the most recent publications written about "Brain-Derived Neurotrophic Factor" by people in Profiles.
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Lee HY, Lee JM, Lee HL, Park J, An H, Park EK, Hwang SY, Yoon SL, Hwang GY, Kim KN, Nam MH, Lee SE, Kang H, Won J, Jang BK, Lee EH, Choi S, Park MG, Kim SW, Park KD, Lee S, Lee CJ, Ha Y. Astrocytic monoamine oxidase B (MAOB)-gamma-aminobutyric acid (GABA) axis as a molecular brake on repair following spinal cord injury. Signal Transduct Target Ther. 2025 Sep 11; 10(1):295.
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Breit MJ, Caldwell AE, Ostendorf DM, Pan Z, Creasy SA, Swanson B, Clark K, Hill EB, MacLean PS, Bessesen DH, Melanson EL, Catenacci VA. Effects of 4:3 Intermittent Fasting on Eating Behaviors and Appetite Hormones: A Secondary Analysis of a 12-Month Behavioral Weight Loss Intervention. Nutrients. 2025 Jul 21; 17(14).
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Russell K, Kearns CA, Walker MB, Knoeckel CS, Ribera AB, Doll CA, Appel B. Bdnf and Ntrk2 functions promote but are not essential for spinal cord myelination in larval zebrafish. Differentiation. 2025 Sep-Oct; 145:100896.
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Nguyen HQD, Nam MH, Vigh J, Brzezinski J, Duncan L, Park D. Co-delivery of neurotrophic factors and a zinc chelator substantially increases retinal ganglion cell survival and axon protection in the optic nerve crush model. Acta Biomater. 2025 Jul 01; 201:297-308.
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Thacker JS, Ralph LT, Koek L, Abbasian A, Bettio LB, Smith AE, Georgiou J, Christie BR, Collingridge GL. Synergistic actions of corticosterone and BDNF on rat hippocampal LTP. Mol Brain. 2025 May 12; 18(1):42.
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Petrill SA, Klamer BG, Buyske S, Willcutt EG, Gruen JR, Francis DJ, Flax JF, Brzustowicz LM, Bartlett CW. The Rosetta Phenotype Harmonization Method Facilitates Finding a Relationship Quantitative Trait Locus for a Complex Cognitive Trait. Genes (Basel). 2023 08 31; 14(9).
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Nizar R, Cazacu S, Xiang C, Krasner M, Barbiro-Michaely E, Gerber D, Schwartz J, Fried I, Yuval S, Brodie A, Kazimirsky G, Amos N, Unger R, Brown S, Rogers L, Penning DH, Brodie C. Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles. Cells. 2023 07 25; 12(15).
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Muscat SM, Deems NP, Butler MJ, Scaria EA, Bettes MN, Cleary SP, Bockbrader RH, Maier SF, Barrientos RM. Selective TLR4 Antagonism Prevents and Reverses Morphine-Induced Persistent Postoperative Cognitive Dysfunction, Dysregulation of Synaptic Elements, and Impaired BDNF Signaling in Aged Male Rats. J Neurosci. 2023 01 04; 43(1):155-172.
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Patterson CG, Joslin E, Gil AB, Spigle W, Nemet T, Chahine L, Christiansen CL, Melanson E, Kohrt WM, Mancini M, Josbeno D, Balfany K, Griffith G, Dunlap MK, Lamotte G, Suttman E, Larson D, Branson C, McKee KE, Goelz L, Poon C, Tilley B, Kang UJ, Tansey MG, Luthra N, Tanner CM, Haus JM, Fantuzzi G, McFarland NR, Gonzalez-Latapi P, Foroud T, Motl R, Schwarzschild MA, Simuni T, Marek K, Naito A, Lungu C, Corcos DM. Study in Parkinson's disease of exercise phase 3 (SPARX3): study protocol for a randomized controlled trial. Trials. 2022 Oct 06; 23(1):855.
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Ng TKS, Coughlan C, Heyn PC, Tagawa A, Carollo JJ, Kua EH, Mahendran R. Increased plasma brain-derived neurotrophic factor (BDNF) as a potential biomarker for and compensatory mechanism in mild cognitive impairment: a case-control study. Aging (Albany NY). 2021 10 15; 13(19):22666-22689.
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