 Brain-Derived Neurotrophic Factor
"Brain-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)
| Descriptor ID |
D019208
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| MeSH Number(s) |
D12.644.276.860.100 D12.776.467.860.100 D12.776.631.600.100 D23.529.850.100
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| Concept/Terms |
Brain-Derived Neurotrophic Factor- Brain-Derived Neurotrophic Factor
- Brain Derived Neurotrophic Factor
- Factor, Brain-Derived Neurotrophic
- Neurotrophic Factor, Brain-Derived
- BDNF
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Below are MeSH descriptors whose meaning is more general than "Brain-Derived Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Brain-Derived Neurotrophic Factor".
This graph shows the total number of publications written about "Brain-Derived Neurotrophic Factor" by people in this website by year, and whether "Brain-Derived Neurotrophic Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 1 | 2 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 0 | 2 | | 2004 | 1 | 0 | 1 | | 2005 | 3 | 2 | 5 | | 2006 | 2 | 1 | 3 | | 2007 | 4 | 1 | 5 | | 2008 | 3 | 1 | 4 | | 2009 | 1 | 1 | 2 | | 2010 | 3 | 0 | 3 | | 2011 | 3 | 2 | 5 | | 2012 | 2 | 1 | 3 | | 2013 | 1 | 3 | 4 | | 2014 | 3 | 4 | 7 | | 2015 | 6 | 2 | 8 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 3 | 4 | | 2018 | 2 | 1 | 3 | | 2019 | 4 | 3 | 7 | | 2021 | 2 | 0 | 2 | | 2022 | 0 | 1 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Brain-Derived Neurotrophic Factor" by people in Profiles.
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Petrill SA, Klamer BG, Buyske S, Willcutt EG, Gruen JR, Francis DJ, Flax JF, Brzustowicz LM, Bartlett CW. The Rosetta Phenotype Harmonization Method Facilitates Finding a Relationship Quantitative Trait Locus for a Complex Cognitive Trait. Genes (Basel). 2023 08 31; 14(9).
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Nizar R, Cazacu S, Xiang C, Krasner M, Barbiro-Michaely E, Gerber D, Schwartz J, Fried I, Yuval S, Brodie A, Kazimirsky G, Amos N, Unger R, Brown S, Rogers L, Penning DH, Brodie C. Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles. Cells. 2023 07 25; 12(15).
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Muscat SM, Deems NP, Butler MJ, Scaria EA, Bettes MN, Cleary SP, Bockbrader RH, Maier SF, Barrientos RM. Selective TLR4 Antagonism Prevents and Reverses Morphine-Induced Persistent Postoperative Cognitive Dysfunction, Dysregulation of Synaptic Elements, and Impaired BDNF Signaling in Aged Male Rats. J Neurosci. 2023 01 04; 43(1):155-172.
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Patterson CG, Joslin E, Gil AB, Spigle W, Nemet T, Chahine L, Christiansen CL, Melanson E, Kohrt WM, Mancini M, Josbeno D, Balfany K, Griffith G, Dunlap MK, Lamotte G, Suttman E, Larson D, Branson C, McKee KE, Goelz L, Poon C, Tilley B, Kang UJ, Tansey MG, Luthra N, Tanner CM, Haus JM, Fantuzzi G, McFarland NR, Gonzalez-Latapi P, Foroud T, Motl R, Schwarzschild MA, Simuni T, Marek K, Naito A, Lungu C, Corcos DM. Study in Parkinson's disease of exercise phase 3 (SPARX3): study protocol for a randomized controlled trial. Trials. 2022 Oct 06; 23(1):855.
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Ng TKS, Coughlan C, Heyn PC, Tagawa A, Carollo JJ, Kua EH, Mahendran R. Increased plasma brain-derived neurotrophic factor (BDNF) as a potential biomarker for and compensatory mechanism in mild cognitive impairment: a case-control study. Aging (Albany NY). 2021 10 15; 13(19):22666-22689.
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Ng TKS, Tagawa A, Ho RC, Larbi A, Kua EH, Mahendran R, Carollo JJ, Heyn PC. Commonalities in biomarkers and phenotypes between mild cognitive impairment and cerebral palsy: a pilot exploratory study. Aging (Albany NY). 2021 01 26; 13(2):1773-1816.
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Johnson TK, Belcher DJ, Sousa CA, Carzoli JP, Visavadiya NP, Khamoui AV, Whitehurst M, Zourdos MC. Low-volume acute multi-joint resistance exercise elicits a circulating brain-derived neurotrophic factor response but not a cathepsin B response in well-trained men. Appl Physiol Nutr Metab. 2020 Dec; 45(12):1332-1338.
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Bharani KL, Ledreux A, Gilmore A, Carroll SL, Granholm AC. Serum pro-BDNF levels correlate with phospho-tau staining in Alzheimer's disease. Neurobiol Aging. 2020 03; 87:49-59.
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Hixson KM, Cogswell M, Brooks-Kayal AR, Russek SJ. Evidence for a non-canonical JAK/STAT signaling pathway in the synthesis of the brain's major ion channels and neurotransmitter receptors. BMC Genomics. 2019 Aug 28; 20(1):677.
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Buck JM, O'Neill HC, Stitzel JA. Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice. Biochem Pharmacol. 2019 10; 168:438-451.
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