 Nicotine
"Nicotine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
| Descriptor ID |
D009538
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| MeSH Number(s) |
D03.132.760.570 D03.383.725.518
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nicotine".
Below are MeSH descriptors whose meaning is more specific than "Nicotine".
This graph shows the total number of publications written about "Nicotine" by people in this website by year, and whether "Nicotine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 4 | 1 | 5 | | 1996 | 0 | 2 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 3 | 0 | 3 | | 1999 | 4 | 1 | 5 | | 2000 | 4 | 4 | 8 | | 2001 | 4 | 0 | 4 | | 2002 | 3 | 1 | 4 | | 2003 | 5 | 6 | 11 | | 2004 | 11 | 1 | 12 | | 2005 | 9 | 2 | 11 | | 2006 | 4 | 3 | 7 | | 2007 | 6 | 2 | 8 | | 2008 | 3 | 2 | 5 | | 2009 | 3 | 3 | 6 | | 2010 | 4 | 2 | 6 | | 2011 | 8 | 0 | 8 | | 2012 | 9 | 7 | 16 | | 2013 | 5 | 7 | 12 | | 2014 | 5 | 1 | 6 | | 2015 | 5 | 3 | 8 | | 2016 | 2 | 1 | 3 | | 2017 | 4 | 2 | 6 | | 2018 | 7 | 2 | 9 | | 2019 | 2 | 2 | 4 | | 2020 | 7 | 2 | 9 | | 2021 | 4 | 3 | 7 | | 2022 | 0 | 5 | 5 | | 2023 | 2 | 4 | 6 | | 2024 | 4 | 2 | 6 |
To return to the timeline, click here.
Below are the most recent publications written about "Nicotine" by people in Profiles.
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Dennison Himmelfarb CR, Benowitz NL, Blank MD, Bhatnagar A, Chase PJ, Davis EM, Fetterman JL, Keller-Hamilton B, Ogungbe O, Page RL, Rezk-Hanna M, Robertson RM, Whitsel LP. Impact of Smokeless Oral Nicotine Products on Cardiovascular Disease: Implications for Policy, Prevention, and Treatment: A Policy Statement From the American Heart Association. Circulation. 2025 Jan 07; 151(1):e1-e21.
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Williams BM, Steed ND, Woolley JT, Moedl AA, Nelson CA, Jones GC, Burris MD, Arias HR, Kim OH, Jang EY, Hone AJ, McIntosh JM, Yorgason JT, Steffensen SC. Catharanthine Modulates Mesolimbic Dopamine Transmission and Nicotine Psychomotor Effects via Inhibition of a6-Nicotinic Receptors and Dopamine Transporters. ACS Chem Neurosci. 2024 05 01; 15(9):1738-1754.
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Guevara A, Smith CER, Caldwell JL, Ngo L, Mott LR, Lee IJ, Tapa S, Wang Z, Wang L, Woodward WR, Ng GA, Habecker BA, Ripplinger CM. Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart. Am J Physiol Heart Circ Physiol. 2024 06 01; 326(6):H1337-H1349.
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Akinola LS, Gonzales J, Buzzi B, Mathews HL, Papke RL, Stitzel JA, Damaj MI. Investigating the role of nicotinic acetylcholine receptors in menthol's effects in mice. Drug Alcohol Depend. 2024 Apr 01; 257:111262.
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Jacobs PS, Jee J, Fang L, Devlin E, Iannelli C, Thakuri D, Loughead J, Epperson CN, Wilson N, Roalf D, Reddy R, Nanga RPR. Application of glutamate weighted CEST in brain imaging of nicotine dependent participants in vivo at 7T. PLoS One. 2024; 19(2):e0297310.
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Avey JP, Schaefer KR, Noonan CJ, Trinidad SB, Muller CJ, Claw KG, Dillard DA, Todd MR, Beans JA, Tyndale RF, Robinson RF, Thummel KE. Identification of Sociodemographic, Clinical, and Genetic Factors to Aid Alaska Native and American Indian People to Successfully Quit Smoking. Nicotine Tob Res. 2024 01 01; 26(1):79-86.
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Rezk-Hanna M, Rossman MJ, Ludwig K, Sakti P, Cheng CW, Brecht ML, Benowitz NL, Seals DR. Electronic hookah (waterpipe) vaping reduces vascular endothelial function: the role of nicotine. Am J Physiol Heart Circ Physiol. 2024 03 01; 326(3):H490-H496.
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Davis DR, Rajesh Kumar L, Morean ME, Kong G, Bold KW, Krishnan-Sarin S, Camenga DE. Why young adults use tobacco-free nicotine E-cigarettes: An analysis of qualitative data. Addict Behav. 2024 03; 150:107925.
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Bai X, Verma D, Garcia C, Musheyev A, Kim K, Fornis L, Griffith DE, Li L, Whittel N, Gadwa J, Ohanjanyan T, Eggleston MJ, Galvan M, Freed BM, Ordway D, Chan ED. Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis. Front Cell Infect Microbiol. 2023; 13:1216492.
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Ozekin YH, Saal ML, Pineda RH, Moehn K, Ordonez-Erives MA, Delgado Figueroa MF, Frazier C, Korth KM, K?nigshoff M, Bates EA, Vladar EK. Intrauterine exposure to nicotine through maternal vaping disrupts embryonic lung and skeletal development via the Kcnj2 potassium channel. Dev Biol. 2023 09; 501:111-123.
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