 Nicotine
"Nicotine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
| Descriptor ID |
D009538
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| MeSH Number(s) |
D03.132.760.570 D03.383.725.518
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nicotine".
Below are MeSH descriptors whose meaning is more specific than "Nicotine".
This graph shows the total number of publications written about "Nicotine" by people in this website by year, and whether "Nicotine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 1998 | 3 | 0 | 3 | | 1999 | 4 | 1 | 5 | | 2000 | 5 | 4 | 9 | | 2001 | 4 | 0 | 4 | | 2002 | 2 | 0 | 2 | | 2003 | 6 | 6 | 12 | | 2004 | 10 | 1 | 11 | | 2005 | 9 | 2 | 11 | | 2006 | 5 | 3 | 8 | | 2007 | 6 | 3 | 9 | | 2008 | 4 | 4 | 8 | | 2009 | 5 | 4 | 9 | | 2010 | 4 | 3 | 7 | | 2011 | 9 | 1 | 10 | | 2012 | 11 | 9 | 20 | | 2013 | 5 | 6 | 11 | | 2014 | 6 | 2 | 8 | | 2015 | 5 | 3 | 8 | | 2016 | 3 | 1 | 4 | | 2017 | 4 | 2 | 6 | | 2018 | 7 | 3 | 10 | | 2019 | 2 | 2 | 4 | | 2020 | 7 | 3 | 10 | | 2021 | 6 | 4 | 10 | | 2022 | 3 | 8 | 11 | | 2023 | 2 | 3 | 5 | | 2024 | 5 | 2 | 7 | | 2025 | 4 | 1 | 5 | | 2026 | 2 | 3 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Nicotine" by people in Profiles.
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Nicoli CD, Chittathoor A, Sharma S. From Aerosol to Epithelium: An Integrated Clinical, Pathologic, and Mechanistic Review of Nicotine and Cannabis Vaporizer Use and Pulmonary Disease. Curr Allergy Asthma Rep. 2026 Oct 17; 26(1).
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Sloan AF, Alexander JD, Ellingson JM, Gustavson DE, Hewitt JK, Hopfer CJ, Iacono WG, McGue M, Rhee SH, Reynolds CA, Vrieze SI, Wilson S, Schaefer JD. Nicotine use and psychoticism: A longitudinal co-twin control analysis. J Psychopathol Clin Sci. 2026 Nov; 135(8):1125-1135.
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Bandoli G, Psaras C, Bakhireva LN, Burris HH, Ciciolla L, Coles CD, DeMauro SB, Osmundson SS, Merhar SL, Smith L, Acheson A, Bogdan R, Croff JM, Cutting LE, Conway KP, Fallin MD, Gao W, Garavan H, Gregory K, Gurka KK, Gurka MJ, Horan HL, Howlett KD, Howell BR, Huang H, Kable JA, LeBlanc KH, Linkersdörfer J, Marienfeld CB, McKelvey LM, Morris AS, Ou X, Peralta-Carcelen M, Pini N, Potter AS, Rogers CE, Sullivan EL, Sun S, Thompson WK, Thomason ME, Volk HE, Wilson S, Zgierska AE, Zink J, Smyser CD, Nelson CA, Chambers CD. Prenatal Substance Exposure and Birth Weight: Findings From the HEALthy Brain and Child Development Study. Pediatrics. 2026 Jun 01; 157(6).
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Kumar PS, Beverly ML, Galindo-Fernandez P, Thompson W, Verma M, Shick E. To Vape or Not to Vape: Oral Health in the Age of Electronic Nicotine Delivery Systems and Electronic Non-Nicotine Delivery Systems. Int Dent J. 2026 Jun; 76(3):109523.
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Buck JM, Melnick M, Stitzel JA. Developmental Nicotine Exposure Induces Intergenerational Transmission of an Ensemble of Neurodevelopmental Disorder-Related Translatomic Perturbations in DRD1-Expressing Striatal Cells of Adolescent Male Mice. Genes (Basel). 2026 Jan 25; 17(2).
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Bauer SE, Macrea M, Casey A, Dagli E, Eakin MN, Farber HJ, Gonzalez P, Hayes D, Hu SW, Kathuria H, Knight SL, Moraes TJ, Neptune ER, Piper ME, Skeen EH, Ueng CS, Upson D, Walley SC, Rao DR. Treatment of Nicotine Use in Adolescents Under 18 Years of Age: An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2025 09; 211(9):1584-1599.
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Aki S, Brown M, Stitzel J, Mathews H. The effects of nicotine on sleep in female C57BL/6J mice. Behav Brain Res. 2025 10 18; 495:115754.
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Gu W, Langlois AWR, Giratallah H, Claw KG, Prasad B, Thummel KE, Tyndale RF. Extending Investigations of miR-126-5p on the Regulation of CYP2A6, the Major Nicotine-Inactivating Enzyme. Pharmacol Res Perspect. 2025 Aug; 13(4):e70149.
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Lombardi AM, Griffioen M, Wong H, Milstead R, Borski C, Shiely E, Bower ME, Schmitt E, LaPlante L, Ehringer MA, Stitzel J, Hoeffer CA. AKT2 Modulates Astrocytic Nicotine Responses In Vivo. Glia. 2025 10; 73(10):2098-2129.
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Durra A, Cherry C, Luo C, Hou E, Frauenpreis A, Purkayastha A, Passamano I, Makanani S, Castillo K, Lund A, Choi W, Sen C, Chandran R, Rickabaugh T, Kaushal P, Bouhaddou M, Vladar EK, Gomperts BN. Unflavored electronic cigarette exposure induces alterations in airway ciliary structure and function. Respir Res. 2025 Jul 02; 26(1):223.
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