 Macular Degeneration
"Macular Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.
| Descriptor ID |
D008268
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| MeSH Number(s) |
C11.768.585.439
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| Concept/Terms |
Macular Degeneration- Macular Degeneration
- Degeneration, Macular
- Degenerations, Macular
- Macular Degenerations
- Age-Related Maculopathies
- Age Related Maculopathies
- Macular Degeneration, Age-Related
- Macular Dystrophy
- Dystrophies, Macular
- Dystrophy, Macular
- Macular Dystrophies
- Maculopathies, Age-Related
- Maculopathies, Age Related
- Maculopathy, Age-Related
- Maculopathy, Age Related
- Age-Related Macular Degeneration
- Age Related Macular Degeneration
- Age-Related Macular Degenerations
- Degeneration, Age-Related Macular
- Degenerations, Age-Related Macular
- Macular Degenerations, Age-Related
- Age-Related Maculopathy
- Age Related Maculopathy
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Below are MeSH descriptors whose meaning is more general than "Macular Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Macular Degeneration".
This graph shows the total number of publications written about "Macular Degeneration" by people in this website by year, and whether "Macular Degeneration" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2002 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 2 | 0 | 2 | | 2006 | 3 | 1 | 4 | | 2007 | 5 | 3 | 8 | | 2008 | 6 | 0 | 6 | | 2009 | 5 | 2 | 7 | | 2010 | 5 | 0 | 5 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 3 | 1 | 4 | | 2014 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 2 | 0 | 2 | | 2021 | 5 | 1 | 6 | | 2022 | 6 | 0 | 6 | | 2023 | 8 | 0 | 8 | | 2024 | 2 | 1 | 3 | | 2025 | 4 | 0 | 4 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Macular Degeneration" by people in Profiles.
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Huang C, Babu VS, Bammidi S, Arnold JN, Ebeling M, Widmer G, Strassburger P, Lazendic M, Grüner S, Koester J, Dutta P, Hose S, Singh S, Gautam P, Lad EM, Westenskow PD, Kutsyr O, Csaky KG, Ghosh S, Sripathi SR, Proia AD, Flores-Bellver M, Sinha D, Feenstra D. STING activation induces polarized cytokine secretion of IFN-ß and IL-17A promoting photoreceptor death and choroidal disruption in age-related macular degeneration. Cell Death Dis. 2026 Feb 27; 17(1).
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Lopez J, de Carlo Forest TE, Azargui S, Gill ZS, Lisker-Cervantes A, Gnanaraj R, Lynch AM, Palestine AG, Mandava N, Mathias MT, Manoharan N, Grove N, Bradley C, Patnaik JL. Visual functioning and geographic atrophy imaging characteristics in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2026 Apr; 264(4):927-934.
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Holt CA, Niedert C, Gedtal M, Virgili G, Hogg RE, Qureshi R. Prognostic factors for age-related macular degeneration progression: An overview of systematic reviews. Surv Ophthalmol. 2026 May-Jun; 71(3):759-773.
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E de Carlo Forest T, Marin AI, Gill Z, Gnanaraj R, Patnaik JL, Poppelaars F, Lynch AM, Palestine AG, Mathias MT, Manoharan N, Frazer-Abel AA, Holers VM, Mandava N. Association between systemic complement levels and choroidal thickness in advanced non-neovascular age-related macular degeneration. Sci Rep. 2025 Dec 06; 16(1):1442.
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Chatterjee S, Ghosh S, Sin Z, Babu VS, Preval LV, Davis E, Tran N, Bammidi S, Gautam P, Hose S, Sergeev Y, Flores-Bellver M, Ritter K, Jessen HJ, Al Diri I, Sinha D, Guha P. Age-Dependent Histone Deacetylase 3 Regulation by ßA3/A1-Crystallin and Inositol Hexaphosphate in Retinal Pigmented Epithelial Cells Reveals a Novel Pathway in Age-Related Macular Degeneration. Aging Cell. 2025 Sep; 24(9):e70163.
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Kang C, Lo JE, Zhang H, Ng SM, Lin JC, Scott IU, Kalpathy-Cramer J, Liu SA, Greenberg PB. Artificial intelligence for diagnosing exudative age-related macular degeneration. Cochrane Database Syst Rev. 2024 10 17; 10:CD015522.
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Lisker-Cervantes A, Gill Z, Patnaik JL, Gnanaraj R, Lynch AM, Palestine AG, Mathias M, Manoharan N, Mandava N, de Carlo Forest TE. Association Between Systemic Levels of Vascular Endothelial Growth Factor and Optical Coherence Tomography Biomarkers in a Non-Neovascular Age-Related Macular Degeneration Cohort. Ophthalmic Surg Lasers Imaging Retina. 2025 Jan; 56(1):23-29.
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Liu A, Anderson KE, Levy J, Johnson TV, Polsky D, Anderson G. Macular Degeneration Drug Prescribing Patterns After Step Therapy Introduction in Medicare Advantage. JAMA Health Forum. 2024 Aug 02; 5(8):e242446.
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Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, Kedziora KM, Stolz DB, Wallace CT, Yu-Wei C, Franks J, Bose D, Shang P, Ambrosino HM, Dutton JR, Geng Z, Montford J, Ryu J, Rajasundaram D, Hose S, Sahel JA, Puertollano R, Finkel T, Zigler JS, Sergeev Y, Watkins SC, Goetzman ES, Ferrington DA, Flores-Bellver M, Kaarniranta K, Sodhi A, Bharti K, Handa JT, Sinha D. The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD. Nat Commun. 2024 Jul 21; 15(1):6150.
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Droho S, Voigt AP, Sterling JK, Rajesh A, Chan KS, Cuda CM, Perlman H, Lavine JA. NR4A1 deletion promotes pro-angiogenic polarization of macrophages derived from classical monocytes in a mouse model of neovascular age-related macular degeneration. J Neuroinflammation. 2023 Oct 19; 20(1):238.
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