Sialyltransferases
"Sialyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of enzymes with the general formula CMP-N-acetylneuraminate:acceptor N-acetylneuraminyl transferase. They catalyze the transfer of N-acetylneuraminic acid from CMP-N-acetylneuraminic acid to an acceptor, which is usually the terminal sugar residue of an oligosaccharide, a glycoprotein, or a glycolipid. EC 2.4.99.-.
Descriptor ID |
D012799
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MeSH Number(s) |
D08.811.913.400.800
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Concept/Terms |
Glycoprotein Sialyltransferase- Glycoprotein Sialyltransferase
- Sialyltransferase, Glycoprotein
- Glycoprotein Sialyltransferases
- Sialyltransferases, Glycoprotein
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Below are MeSH descriptors whose meaning is more general than "Sialyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Sialyltransferases".
This graph shows the total number of publications written about "Sialyltransferases" by people in this website by year, and whether "Sialyltransferases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 1996 | 2 | 0 | 2 | 1997 | 1 | 0 | 1 | 1998 | 2 | 0 | 2 | 1999 | 0 | 1 | 1 | 2011 | 0 | 2 | 2 | 2016 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sialyltransferases" by people in Profiles.
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Zhou X, Kinlough CL, Hughey RP, Jin M, Inoue H, Etling E, Modena BD, Kaminski N, Bleecker ER, Meyers DA, Jarjour NN, Trudeau JB, Holguin F, Ray A, Wenzel SE. Sialylation of MUC4? N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation. JCI Insight. 2019 03 07; 4(5).
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Neel DS, Allegakoen DV, Olivas V, Mayekar MK, Hemmati G, Chatterjee N, Blakely CM, McCoach CE, Rotow JK, Le A, Karachaliou N, Rosell R, Riess JW, Nichols R, Doebele RC, Bivona TG. Differential Subcellular Localization Regulates Oncogenic Signaling by ROS1 Kinase Fusion Proteins. Cancer Res. 2019 02 01; 79(3):546-556.
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Eby JM, Barse L, Henning SW, Rabelink MJ, Klarquist J, Gilbert ER, Hammer AM, Fernandez MF, Yung N, Khan S, Miller HG, Kessler ER, Garrett-Mayer E, Dilling DF, Hoeben RC, Le Poole IC. Alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 can support immune responses toward tumors overexpressing ganglioside D3 in mice. Cancer Immunol Immunother. 2017 01; 66(1):63-75.
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Dorrell C, Schug J, Canaday PS, Russ HA, Tarlow BD, Grompe MT, Horton T, Hebrok M, Streeter PR, Kaestner KH, Grompe M. Human islets contain four distinct subtypes of ? cells. Nat Commun. 2016 07 11; 7:11756.
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Nakano TA, Steirer LM, Moe GR. The expression profile of de-N-acetyl polysialic acid (NeuPSA) in normal and diseased human tissue. J Biol Chem. 2011 Nov 18; 286(46):40343-53.
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Houliston RS, Vinogradov E, Dzieciatkowska M, Li J, St Michael F, Karwaski MF, Brochu D, Jarrell HC, Parker CT, Yuki N, Mandrell RE, Gilbert M. Lipooligosaccharide of Campylobacter jejuni: similarity with multiple types of mammalian glycans beyond gangliosides. J Biol Chem. 2011 Apr 08; 286(14):12361-70.
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McFarlane I, Georgopoulou N, Coughlan CM, Gillian AM, Breen KC. The role of the protein glycosylation state in the control of cellular transport of the amyloid beta precursor protein. Neuroscience. 1999 Apr; 90(1):15-25.
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Coughlan CM, Breen KC. Glucocorticoid induction of the alpha2,6 sialyltransferase enzyme in a mouse neural cell line. J Neurosci Res. 1998 Mar 01; 51(5):619-26.
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Maguire TM, Coughlan CM, Seckl JR, Breen KC. The effect of corticosteroids on serum sialyltransferase enzyme activities in the rat. Biochim Biophys Acta. 1998 Jan 08; 1379(1):23-8.
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Coughlan CM, Burger PG, Berger EG, Breen KC. The biochemical consequences of alpha2,6(N) sialyltransferase induction by dexamethasone on sialoglycoprotein expression in the rat H411e hepatoma cell line. FEBS Lett. 1997 Aug 18; 413(2):389-93.
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