 Interleukin-6
"Interleukin-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
| Descriptor ID |
D015850
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| MeSH Number(s) |
D12.644.276.374.465.224 D12.776.467.374.465.202 D23.529.374.465.224
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| Concept/Terms |
Interleukin-6- Interleukin-6
- Interleukin 6
- IL6
- B-Cell Stimulatory Factor 2
- B-Cell Stimulatory Factor-2
- Differentiation Factor-2, B-Cell
- Differentiation Factor 2, B Cell
- B-Cell Differentiation Factor-2
- B Cell Differentiation Factor 2
- BSF-2
- Hybridoma Growth Factor
- Growth Factor, Hybridoma
- IFN-beta 2
- Plasmacytoma Growth Factor
- Growth Factor, Plasmacytoma
- Hepatocyte-Stimulating Factor
- Hepatocyte Stimulating Factor
- MGI-2
- Myeloid Differentiation-Inducing Protein
- Differentiation-Inducing Protein, Myeloid
- Myeloid Differentiation Inducing Protein
- B-Cell Differentiation Factor
- B Cell Differentiation Factor
- Differentiation Factor, B-Cell
- Differentiation Factor, B Cell
- IL-6
- Interferon beta-2
- Interferon beta 2
- beta-2, Interferon
- B Cell Stimulatory Factor-2
- B Cell Stimulatory Factor 2
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Below are MeSH descriptors whose meaning is more general than "Interleukin-6".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-6".
This graph shows the total number of publications written about "Interleukin-6" by people in this website by year, and whether "Interleukin-6" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 3 | 8 | | 1996 | 4 | 2 | 6 | | 1997 | 4 | 6 | 10 | | 1998 | 4 | 7 | 11 | | 1999 | 6 | 7 | 13 | | 2000 | 3 | 3 | 6 | | 2001 | 2 | 5 | 7 | | 2002 | 0 | 7 | 7 | | 2003 | 3 | 11 | 14 | | 2004 | 6 | 7 | 13 | | 2005 | 4 | 12 | 16 | | 2006 | 5 | 11 | 16 | | 2007 | 11 | 8 | 19 | | 2008 | 6 | 15 | 21 | | 2009 | 7 | 21 | 28 | | 2010 | 7 | 9 | 16 | | 2011 | 3 | 14 | 17 | | 2012 | 6 | 13 | 19 | | 2013 | 5 | 14 | 19 | | 2014 | 6 | 21 | 27 | | 2015 | 4 | 11 | 15 | | 2016 | 2 | 14 | 16 | | 2017 | 4 | 3 | 7 | | 2018 | 6 | 10 | 16 | | 2019 | 3 | 9 | 12 | | 2020 | 9 | 12 | 21 | | 2021 | 7 | 8 | 15 | | 2022 | 6 | 12 | 18 | | 2023 | 3 | 9 | 12 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-6" by people in Profiles.
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Desmond LW, Holbrook EM, Wright CTO, Zambrano CA, Stamper CE, Bohr AD, Frank MG, Podell BK, Moreno JA, MacDonald AS, Reber SO, Hern?ndez-Pando R, Lowry CA. Effects of Mycobacterium vaccae NCTC 11659 and Lipopolysaccharide Challenge on Polarization of Murine BV-2 Microglial Cells. Int J Mol Sci. 2023 Dec 29; 25(1).
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Haystead T, Lee E, Cho K, Gullickson G, Hughes P, Krafsur G, Freeze R, Scarneo S. Investigation of SARS-CoV-2 individual proteins reveals the in vitro and in vivo immunogenicity of membrane protein. Sci Rep. 2023 12 18; 13(1):22873.
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Foley KE, Winder Z, Sudduth TL, Martin BJ, Nelson PT, Jicha GA, Harp JP, Weekman EM, Wilcock DM. Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort. Alzheimers Dement. 2024 02; 20(2):1374-1386.
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Metcalf CA, Johnson RL, Duffy KA, Freeman EW, Sammel MD, Epperson CN. Depressed, stressed, and inflamed: C-reactive protein linked with depression symptoms in midlife women with both childhood and current life stress. Stress Health. 2024 Apr; 40(2):e3313.
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Castleman MJ, Santos AL, Lesteberg KE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. Activation and pro-inflammatory cytokine production by unswitched memory B cells during SARS-CoV-2 infection. Front Immunol. 2023; 14:1213344.
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Khair S, Walrath TM, Curtis BJ, Orlicky DJ, McMahan RH, Kovacs EJ. Ethanol exacerbates pulmonary complications after burn injury in mice, regardless of frequency of ethanol exposures. Burns. 2023 12; 49(8):1935-1943.
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Okamura K, Lu S, He Z, Altmann C, Montford JR, Li AS, Lucia MS, Orlicky DJ, Weiser-Evans M, Faubel S. IL-6 mediates the hepatic acute phase response after prerenal azotemia in a clinically defined murine model. Am J Physiol Renal Physiol. 2023 09 01; 325(3):F328-F344.
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Ghezzi P, Fantuzzi G, Dinarello CA. Perspective: Daniela Novick, cytokines and their receptors. Front Immunol. 2023; 14:1160651.
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Dolly A, P?tgens SA, Thibaut MM, Neyrinck AM, de Castro GS, Galbert C, Lefevre C, Wyart E, Gomes SP, Gon?alves DC, Lanthier N, Baldin P, Huot JR, Bonetto A, Seelaender M, Delzenne NM, Sokol H, Bindels LB. Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia. J Cachexia Sarcopenia Muscle. 2023 06; 14(3):1569-1582.
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Flux MC, Smith DG, Allen JJB, Mehl MR, Medrano A, Begay TK, Middlemist BH, Marquart BM, Cole SP, Sauder CJ, Lowry CA, Raison CL. Association of plasma cytokines and antidepressant response following mild-intensity whole-body hyperthermia in major depressive disorder. Transl Psychiatry. 2023 04 21; 13(1):132.
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