Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Kenneth Malcolm

Concepts (312)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Mycobacterium abscessus
11
2025
118
3.950
Why?
Mycobacterium Infections, Nontuberculous
16
2025
366
3.050
Why?
Neutrophils
30
2025
1134
2.660
Why?
Host-Pathogen Interactions
4
2025
371
1.720
Why?
Cystic Fibrosis
16
2025
1158
1.610
Why?
Phagocytosis
8
2026
299
1.100
Why?
Azithromycin
4
2020
104
0.840
Why?
Immunity, Humoral
1
2025
120
0.830
Why?
Interferons
2
2016
188
0.750
Why?
Lipopolysaccharides
11
2025
863
0.740
Why?
Gene Expression Regulation
7
2020
2603
0.690
Why?
Immunity, Innate
3
2025
846
0.630
Why?
Klebsiella pneumoniae
2
2018
47
0.590
Why?
Pseudomonas
1
2018
32
0.580
Why?
Pseudomonas aeruginosa
8
2022
356
0.550
Why?
Fomites
1
2017
7
0.530
Why?
Cytotoxicity, Immunologic
1
2018
223
0.530
Why?
Nontuberculous Mycobacteria
7
2025
208
0.520
Why?
Anti-Bacterial Agents
11
2024
1906
0.490
Why?
Mitogen-Activated Protein Kinases
7
2004
292
0.400
Why?
Pseudomonas Infections
5
2022
221
0.390
Why?
Myelodysplastic Syndromes
2
2026
147
0.390
Why?
Neutrophil Activation
1
2013
85
0.370
Why?
Mycobacterium Infections
1
2013
61
0.370
Why?
Reactive Oxygen Species
4
2020
621
0.370
Why?
Staphylococcus aureus
3
2015
454
0.350
Why?
Mycobacterium
1
2013
116
0.350
Why?
Superoxides
5
2018
204
0.340
Why?
Bacteria
1
2018
889
0.330
Why?
Sputum
5
2025
308
0.330
Why?
Microbial Viability
3
2018
90
0.300
Why?
Immunoglobulin G
2
2025
893
0.300
Why?
Biofilms
5
2014
278
0.280
Why?
Extracellular Traps
2
2018
57
0.260
Why?
Immunoglobulin M
2
2025
284
0.240
Why?
Interleukin-8
3
2020
271
0.240
Why?
Humans
46
2026
144261
0.240
Why?
Macrophages
5
2026
1510
0.220
Why?
Mannose-Binding Lectin
1
2025
20
0.220
Why?
Phage Therapy
1
2025
17
0.220
Why?
Extracellular Space
2
2018
120
0.220
Why?
Gene Expression Profiling
3
2018
1782
0.220
Why?
Cell Separation
3
2016
307
0.210
Why?
Oligonucleotide Array Sequence Analysis
3
2002
758
0.210
Why?
Antibodies, Bacterial
1
2025
148
0.210
Why?
Complement C3
1
2025
191
0.200
Why?
Tobramycin
4
2016
54
0.190
Why?
Toll-Like Receptors
3
2017
194
0.190
Why?
Cytokines
8
2018
2061
0.190
Why?
GTP-Binding Proteins
1
2003
153
0.180
Why?
Antimalarials
1
2022
35
0.180
Why?
p38 Mitogen-Activated Protein Kinases
7
2011
266
0.180
Why?
Primary Cell Culture
2
2020
173
0.180
Why?
Complement Activation
1
2025
411
0.180
Why?
Disease Models, Animal
6
2026
4556
0.170
Why?
Case-Control Studies
3
2020
3592
0.170
Why?
Pneumonia, Bacterial
3
2013
113
0.170
Why?
Chemokine CCL4
1
2020
31
0.160
Why?
Bacteriophages
1
2022
111
0.160
Why?
Chloroquine
1
2020
53
0.160
Why?
RNA Splicing
2
2023
284
0.160
Why?
Mycobacterium tuberculosis
1
2022
334
0.150
Why?
Sirolimus
1
2020
281
0.140
Why?
Intracellular Space
1
2018
66
0.130
Why?
Autophagy
1
2020
285
0.130
Why?
Mice
15
2026
18329
0.130
Why?
Respiratory System
1
2018
149
0.130
Why?
Adaptor Proteins, Signal Transducing
1
2020
427
0.130
Why?
Lung
9
2024
4108
0.130
Why?
Aztreonam
1
2016
11
0.130
Why?
Antiviral Agents
1
2003
767
0.130
Why?
Leukemia, Myeloid, Acute
1
2023
682
0.120
Why?
Signal Transduction
3
2020
5221
0.120
Why?
C-Reactive Protein
1
2018
416
0.120
Why?
Survival Analysis
2
2016
1382
0.120
Why?
Immunosuppressive Agents
1
2020
846
0.110
Why?
Interferon-alpha
1
2016
197
0.110
Why?
Alternative Splicing
1
2017
247
0.110
Why?
Microbial Sensitivity Tests
4
2022
370
0.110
Why?
Antimicrobial Cationic Peptides
1
2015
86
0.110
Why?
Severity of Illness Index
4
2018
2917
0.110
Why?
Granulomatous Disease, Chronic
1
2014
48
0.110
Why?
Leukocytes, Mononuclear
1
2017
573
0.110
Why?
Metalloproteases
1
2014
42
0.110
Why?
Oxidants
1
2014
103
0.110
Why?
Cell Movement
4
2013
965
0.110
Why?
RNA, Messenger
3
2022
2829
0.110
Why?
Phagocytes
1
2014
81
0.100
Why?
Deoxyribonucleases
2
2011
24
0.100
Why?
Thiazolidinediones
1
2014
138
0.100
Why?
Kaplan-Meier Estimate
1
2016
964
0.100
Why?
Quorum Sensing
1
2014
79
0.100
Why?
Odds Ratio
1
2016
1072
0.100
Why?
Tumor Necrosis Factor-alpha
5
2011
1217
0.100
Why?
Animals
16
2026
38030
0.100
Why?
Cell Death
2
2013
383
0.100
Why?
Male
14
2026
72035
0.100
Why?
Virulence Factors
1
2014
172
0.100
Why?
Rhinitis
1
2015
171
0.090
Why?
Multivariate Analysis
1
2016
1533
0.090
Why?
Prospective Studies
5
2025
7970
0.090
Why?
Wound Infection
1
2013
55
0.090
Why?
Sinusitis
1
2015
228
0.090
Why?
Cellular Structures
1
2011
6
0.090
Why?
Lipid Metabolism
1
2015
525
0.090
Why?
Contact Lenses, Hydrophilic
1
2011
6
0.090
Why?
Myocytes, Smooth Muscle
1
2013
266
0.090
Why?
Neutrophil Infiltration
3
2013
104
0.090
Why?
Actins
3
2009
422
0.080
Why?
Chemokine CXCL5
1
2011
19
0.080
Why?
Cell Lineage
1
2013
376
0.080
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
1
2013
297
0.080
Why?
Female
13
2026
77976
0.080
Why?
Eye Infections, Bacterial
1
2011
44
0.080
Why?
Treatment Outcome
4
2025
11643
0.080
Why?
Interleukin-17
1
2011
118
0.080
Why?
Lipids
1
2015
700
0.080
Why?
Biomarkers
4
2025
4254
0.080
Why?
Species Specificity
1
2011
574
0.080
Why?
Viruses
1
2011
165
0.070
Why?
Tumor Suppressor Protein p53
1
2013
529
0.070
Why?
Retroviridae
1
2008
101
0.070
Why?
cdc42 GTP-Binding Protein
2
2006
22
0.070
Why?
Pulmonary Alveoli
1
2011
383
0.070
Why?
Peptides
2
2011
995
0.070
Why?
Transgenes
1
2008
189
0.070
Why?
Mitochondria
1
2014
983
0.070
Why?
Burns
1
2013
376
0.070
Why?
Kruppel-Like Transcription Factors
1
2008
78
0.070
Why?
Adult
8
2025
40262
0.060
Why?
Pulmonary Artery
1
2013
1134
0.060
Why?
Bone Marrow
1
2008
304
0.060
Why?
Adaptor Proteins, Vesicular Transport
1
2007
44
0.060
Why?
Membrane Glycoproteins
2
2014
496
0.060
Why?
Endothelium, Vascular
1
2013
963
0.060
Why?
rhoA GTP-Binding Protein
1
2006
76
0.060
Why?
Escherichia coli Infections
1
2007
129
0.060
Why?
Up-Regulation
3
2006
851
0.060
Why?
Cohort Studies
2
2020
5935
0.060
Why?
Cell Culture Techniques
1
2008
375
0.060
Why?
Middle Aged
4
2020
35762
0.060
Why?
Hydroxyeicosatetraenoic Acids
1
2005
35
0.060
Why?
Inflammation
5
2022
2877
0.060
Why?
Respiratory Mucosa
1
2008
322
0.060
Why?
MAP Kinase Signaling System
1
2007
309
0.050
Why?
Toll-Like Receptor 4
2
2007
276
0.050
Why?
Dinoprostone
1
2005
178
0.050
Why?
DNA
2
2009
1460
0.050
Why?
Drug Therapy, Combination
3
2013
1044
0.050
Why?
Membrane Microdomains
1
2004
34
0.050
Why?
Inflammation Mediators
2
2011
508
0.050
Why?
beta-Cyclodextrins
1
2004
32
0.050
Why?
Transcription, Genetic
4
2008
1495
0.050
Why?
Enzyme Precursors
1
2003
15
0.050
Why?
Chemokines, CXC
1
2004
68
0.050
Why?
NF-kappa B
4
2013
661
0.050
Why?
Receptors, CXCR4
1
2004
91
0.050
Why?
Mutation
2
2026
4085
0.050
Why?
Zymosan
1
2023
39
0.050
Why?
Splicing Factor U2AF
1
2023
18
0.050
Why?
Multicenter Studies as Topic
1
2025
402
0.050
Why?
Drug Evaluation, Preclinical
1
2024
194
0.050
Why?
Myxovirus Resistance Proteins
1
2003
13
0.050
Why?
Mycobacterium avium
1
2023
21
0.050
Why?
Bacterial Load
2
2015
67
0.050
Why?
Young Adult
3
2020
13990
0.050
Why?
eIF-2 Kinase
1
2003
29
0.050
Why?
Chemotaxis
1
2023
122
0.050
Why?
STAT1 Transcription Factor
1
2003
68
0.050
Why?
Enzyme Activation
4
2008
765
0.050
Why?
Anti-Inflammatory Agents, Non-Steroidal
2
2002
338
0.050
Why?
Phosphoprotein Phosphatases
1
2002
65
0.050
Why?
Escherichia coli
1
2007
852
0.050
Why?
Macrophages, Alveolar
1
2005
368
0.050
Why?
Cell Differentiation
2
2026
2048
0.040
Why?
Toll-Like Receptor 2
1
2003
126
0.040
Why?
Risk Factors
1
2016
10699
0.040
Why?
Interferon Type I
1
2003
145
0.040
Why?
Gene Expression
2
2008
1487
0.040
Why?
Phosphatidylinositol 3-Kinases
1
2003
379
0.040
Why?
STAT3 Transcription Factor
1
2003
207
0.040
Why?
Ciprofloxacin
2
2013
26
0.040
Why?
Transcriptional Activation
2
2013
382
0.040
Why?
Gene Expression Regulation, Enzymologic
1
2002
269
0.040
Why?
Receptors, Cell Surface
1
2003
377
0.040
Why?
Administration, Inhalation
1
2022
574
0.040
Why?
Apoptosis
2
2008
2430
0.040
Why?
Protein-Tyrosine Kinases
1
2003
433
0.040
Why?
Trans-Activators
1
2003
405
0.040
Why?
Clinical Trials as Topic
1
2025
1050
0.040
Why?
Glycolipids
1
2020
52
0.040
Why?
Mice, Knockout
3
2014
3119
0.040
Why?
Complement System Proteins
1
2023
316
0.040
Why?
Transforming Growth Factor beta
1
2002
479
0.040
Why?
Aged, 80 and over
1
2011
8243
0.040
Why?
Time Factors
3
2018
7155
0.040
Why?
British Columbia
1
2018
23
0.030
Why?
Bronchoalveolar Lavage Fluid
2
2015
636
0.030
Why?
Mice, Transgenic
1
2023
2182
0.030
Why?
Chemokine CXCL1
2
2011
76
0.030
Why?
Cell Migration Inhibition
2
2011
16
0.030
Why?
Chemotaxis, Leukocyte
2
2011
113
0.030
Why?
Morbidity
1
2018
323
0.030
Why?
Drug Administration Routes
1
2016
42
0.030
Why?
Imidazoles
3
2002
254
0.030
Why?
RNA Precursors
1
2017
156
0.030
Why?
Proteins
1
2002
1021
0.030
Why?
Mice, Inbred C57BL
4
2011
5988
0.030
Why?
Drug Interactions
1
2016
397
0.030
Why?
Cathelicidins
1
2015
41
0.030
Why?
DNA-Binding Proteins
1
2003
1497
0.030
Why?
Aged
2
2015
25850
0.030
Why?
NADPH Oxidase 2
1
2014
35
0.030
Why?
Respiratory Function Tests
1
2016
546
0.030
Why?
Predictive Value of Tests
1
2020
2111
0.030
Why?
Gentamicins
1
2015
51
0.030
Why?
Chronic Disease
2
2015
1812
0.030
Why?
Enzyme Inhibitors
3
2002
824
0.030
Why?
Reproducibility of Results
1
2002
3403
0.030
Why?
Pilot Projects
1
2020
1867
0.030
Why?
NADPH Oxidases
1
2014
124
0.030
Why?
Drug Resistance, Multiple, Bacterial
1
2014
81
0.030
Why?
Recombinant Proteins
2
2011
1367
0.030
Why?
Drug Resistance, Bacterial
1
2015
196
0.030
Why?
PPAR gamma
1
2014
176
0.030
Why?
Asthma
1
2005
1767
0.020
Why?
Drug Monitoring
1
2016
389
0.020
Why?
Survival Rate
1
2018
2088
0.020
Why?
JNK Mitogen-Activated Protein Kinases
2
2003
153
0.020
Why?
Spleen
1
2015
508
0.020
Why?
Chemokine CCL2
2
2003
115
0.020
Why?
Leukocyte Count
1
2013
316
0.020
Why?
Adenoviridae
1
2013
199
0.020
Why?
Cell Hypoxia
1
2013
247
0.020
Why?
Gene Knockdown Techniques
1
2013
336
0.020
Why?
Fibrinogen
1
2013
176
0.020
Why?
Drug Synergism
1
2013
357
0.020
Why?
Down-Regulation
2
2006
627
0.020
Why?
Neovascularization, Physiologic
1
2013
194
0.020
Why?
Monocytes
1
2014
538
0.020
Why?
Suspensions
1
2011
29
0.020
Why?
Gene Deletion
1
2013
387
0.020
Why?
Chemokine CXCL2
1
2011
41
0.020
Why?
Corneal Ulcer
1
2011
20
0.020
Why?
Epithelium, Corneal
1
2011
41
0.020
Why?
RNA, Small Interfering
1
2013
634
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
2
2003
981
0.020
Why?
Genome
1
2013
306
0.020
Why?
Bacterial Adhesion
1
2011
109
0.020
Why?
Methacrylates
1
2011
119
0.020
Why?
Anti-Infective Agents
1
2013
242
0.020
Why?
Disease Progression
1
2018
2840
0.020
Why?
Cell Adhesion
1
2011
454
0.020
Why?
Rabbits
1
2011
648
0.020
Why?
Cell Line
2
2008
2879
0.020
Why?
Prognosis
1
2018
4278
0.020
Why?
Granulocytes
1
2008
80
0.020
Why?
Follow-Up Studies
1
2018
5389
0.020
Why?
Nitric Oxide
1
2013
897
0.020
Why?
Enzyme Induction
1
2008
88
0.020
Why?
Colorado
1
2018
4562
0.020
Why?
Nitric Oxide Synthase Type II
1
2008
162
0.020
Why?
Pyridines
2
2002
605
0.020
Why?
Acute Lung Injury
1
2011
302
0.020
Why?
Cystic Fibrosis Transmembrane Conductance Regulator
1
2011
370
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
1
2008
240
0.020
Why?
Toll-Like Receptor 3
1
2007
28
0.020
Why?
NF-KappaB Inhibitor alpha
1
2006
49
0.020
Why?
Mitogen-Activated Protein Kinase Kinases
1
2007
128
0.020
Why?
I-kappa B Proteins
1
2006
74
0.020
Why?
Cell Proliferation
1
2013
2494
0.010
Why?
Keratinocytes
1
2007
248
0.010
Why?
Jurkat Cells
1
2005
114
0.010
Why?
Child
2
2020
22537
0.010
Why?
Cyclodextrins
1
2004
11
0.010
Why?
rac GTP-Binding Proteins
1
2004
34
0.010
Why?
Vital Capacity
1
2005
290
0.010
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
1
2005
161
0.010
Why?
Receptors, Interleukin-8B
1
2004
23
0.010
Why?
Syk Kinase
1
2003
22
0.010
Why?
Forced Expiratory Volume
1
2005
448
0.010
Why?
rho GTP-Binding Proteins
1
2004
56
0.010
Why?
Anthracenes
1
2003
31
0.010
Why?
Chemokine CXCL12
1
2004
89
0.010
Why?
Cells, Cultured
1
2011
4146
0.010
Why?
Chemokines
1
2004
218
0.010
Why?
Promoter Regions, Genetic
1
2008
1255
0.010
Why?
Cross-Sectional Studies
1
2015
5813
0.010
Why?
Dexamethasone
1
2005
370
0.010
Why?
DNA Primers
1
2003
511
0.010
Why?
Precipitin Tests
1
2002
93
0.010
Why?
Bone Marrow Cells
1
2004
320
0.010
Why?
Analysis of Variance
1
2005
1304
0.010
Why?
Cholesterol
1
2004
399
0.010
Why?
Protein Phosphatase 2
1
2002
41
0.010
Why?
Electrophoresis, Gel, Two-Dimensional
1
2002
110
0.010
Why?
Cell Survival
1
2005
1098
0.010
Why?
Intubation, Gastrointestinal
1
2002
82
0.010
Why?
Aminopyridines
1
2002
127
0.010
Why?
Ligands
1
2004
673
0.010
Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
1
2002
143
0.010
Why?
Transcription Factor AP-1
1
2002
79
0.010
Why?
Anti-Inflammatory Agents
1
2005
474
0.010
Why?
Epithelial Cells
1
2008
1125
0.010
Why?
Intracellular Signaling Peptides and Proteins
1
2003
459
0.010
Why?
Adolescent
1
2020
22281
0.010
Why?
Drug Administration Schedule
1
2002
778
0.010
Why?
In Vitro Techniques
1
2002
1047
0.010
Why?
Base Sequence
1
2003
2187
0.010
Why?
Homeostasis
1
2004
640
0.010
Why?
Amino Acid Sequence
1
2002
2154
0.010
Why?
Proteome
1
2002
514
0.010
Why?
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