Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Kenneth Malcolm

Concepts (313)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Mycobacterium abscessus
11
2025
115
4.060
Why?
Mycobacterium Infections, Nontuberculous
16
2025
357
3.160
Why?
Neutrophils
30
2025
1274
2.730
Why?
Host-Pathogen Interactions
4
2025
368
1.770
Why?
Cystic Fibrosis
16
2025
1102
1.690
Why?
Phagocytosis
7
2025
387
1.050
Why?
Azithromycin
4
2020
97
0.870
Why?
Immunity, Humoral
1
2025
115
0.860
Why?
Interferons
2
2016
195
0.770
Why?
Lipopolysaccharides
11
2025
888
0.760
Why?
Gene Expression Regulation
7
2020
2590
0.700
Why?
Immunity, Innate
3
2025
824
0.650
Why?
Klebsiella pneumoniae
2
2018
46
0.610
Why?
Pseudomonas
1
2018
30
0.590
Why?
Pseudomonas aeruginosa
8
2022
348
0.570
Why?
Fomites
1
2017
7
0.550
Why?
Cytotoxicity, Immunologic
1
2018
224
0.540
Why?
Nontuberculous Mycobacteria
7
2025
201
0.540
Why?
Anti-Bacterial Agents
11
2024
1818
0.520
Why?
Mitogen-Activated Protein Kinases
7
2004
316
0.400
Why?
Pseudomonas Infections
5
2022
221
0.400
Why?
Neutrophil Activation
1
2013
85
0.390
Why?
Reactive Oxygen Species
4
2020
624
0.380
Why?
Mycobacterium Infections
1
2013
62
0.380
Why?
Staphylococcus aureus
3
2015
433
0.370
Why?
Mycobacterium
1
2013
110
0.360
Why?
Superoxides
5
2018
217
0.350
Why?
Bacteria
1
2018
867
0.350
Why?
Sputum
5
2025
305
0.330
Why?
Microbial Viability
3
2018
91
0.310
Why?
Immunoglobulin G
2
2025
898
0.310
Why?
Biofilms
5
2014
265
0.290
Why?
Extracellular Traps
2
2018
53
0.270
Why?
Immunoglobulin M
2
2025
287
0.250
Why?
Interleukin-8
3
2020
271
0.250
Why?
Humans
45
2025
138651
0.250
Why?
Mannose-Binding Lectin
1
2025
21
0.230
Why?
Phage Therapy
1
2025
16
0.230
Why?
Extracellular Space
2
2018
129
0.220
Why?
Gene Expression Profiling
3
2018
1746
0.220
Why?
Cell Separation
3
2016
317
0.220
Why?
Oligonucleotide Array Sequence Analysis
3
2002
761
0.220
Why?
Antibodies, Bacterial
1
2025
145
0.220
Why?
Complement C3
1
2025
201
0.210
Why?
Tobramycin
4
2016
52
0.200
Why?
Toll-Like Receptors
3
2017
189
0.190
Why?
Cytokines
8
2018
2080
0.190
Why?
GTP-Binding Proteins
1
2003
152
0.190
Why?
Antimalarials
1
2022
32
0.180
Why?
p38 Mitogen-Activated Protein Kinases
7
2011
280
0.180
Why?
Complement Activation
1
2025
403
0.180
Why?
Primary Cell Culture
2
2020
171
0.180
Why?
Myelodysplastic Syndromes
1
2023
140
0.180
Why?
Case-Control Studies
3
2020
3523
0.180
Why?
Pneumonia, Bacterial
3
2013
114
0.170
Why?
Bacteriophages
1
2022
98
0.170
Why?
Chemokine CCL4
1
2020
22
0.170
Why?
RNA Splicing
2
2023
270
0.160
Why?
Chloroquine
1
2020
52
0.160
Why?
Mycobacterium tuberculosis
1
2022
315
0.150
Why?
Disease Models, Animal
5
2024
4315
0.150
Why?
Sirolimus
1
2020
277
0.140
Why?
Intracellular Space
1
2018
68
0.140
Why?
Autophagy
1
2020
285
0.140
Why?
Lung
9
2024
4106
0.130
Why?
Respiratory System
1
2018
157
0.130
Why?
Adaptor Proteins, Signal Transducing
1
2020
428
0.130
Why?
Aztreonam
1
2016
11
0.130
Why?
Antiviral Agents
1
2003
735
0.130
Why?
Leukemia, Myeloid, Acute
1
2023
633
0.130
Why?
Signal Transduction
3
2020
5086
0.120
Why?
Mice
14
2024
17814
0.120
Why?
Survival Analysis
2
2016
1309
0.120
Why?
C-Reactive Protein
1
2018
415
0.120
Why?
Immunosuppressive Agents
1
2020
849
0.120
Why?
Alternative Splicing
1
2017
227
0.120
Why?
Interferon-alpha
1
2016
195
0.120
Why?
Microbial Sensitivity Tests
4
2022
351
0.110
Why?
Severity of Illness Index
4
2018
2851
0.110
Why?
Antimicrobial Cationic Peptides
1
2015
81
0.110
Why?
RNA, Messenger
3
2022
2815
0.110
Why?
Cell Movement
4
2013
969
0.110
Why?
Granulomatous Disease, Chronic
1
2014
59
0.110
Why?
Metalloproteases
1
2014
42
0.110
Why?
Leukocytes, Mononuclear
1
2017
571
0.110
Why?
Oxidants
1
2014
112
0.110
Why?
Deoxyribonucleases
2
2011
24
0.110
Why?
Phagocytes
1
2014
103
0.110
Why?
Kaplan-Meier Estimate
1
2016
896
0.110
Why?
Thiazolidinediones
1
2014
138
0.100
Why?
Quorum Sensing
1
2014
73
0.100
Why?
Odds Ratio
1
2016
1044
0.100
Why?
Tumor Necrosis Factor-alpha
5
2011
1244
0.100
Why?
Cell Death
2
2013
375
0.100
Why?
Virulence Factors
1
2014
157
0.100
Why?
Rhinitis
1
2015
171
0.100
Why?
Multivariate Analysis
1
2016
1482
0.100
Why?
Wound Infection
1
2013
35
0.100
Why?
Prospective Studies
5
2025
7554
0.090
Why?
Male
13
2025
68260
0.090
Why?
Sinusitis
1
2015
237
0.090
Why?
Cellular Structures
1
2011
6
0.090
Why?
Lipid Metabolism
1
2015
522
0.090
Why?
Animals
15
2024
37217
0.090
Why?
Contact Lenses, Hydrophilic
1
2011
7
0.090
Why?
Macrophages
4
2023
1543
0.090
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
1
2013
285
0.090
Why?
Myocytes, Smooth Muscle
1
2013
259
0.090
Why?
Basic Helix-Loop-Helix Transcription Factors
1
2013
245
0.090
Why?
Actins
3
2009
419
0.090
Why?
Neutrophil Infiltration
3
2013
108
0.090
Why?
Cell Lineage
1
2013
350
0.090
Why?
Chemokine CXCL5
1
2011
12
0.090
Why?
Treatment Outcome
4
2025
10923
0.090
Why?
Eye Infections, Bacterial
1
2011
39
0.080
Why?
Lipids
1
2015
675
0.080
Why?
Biomarkers
4
2025
4092
0.080
Why?
Interleukin-17
1
2011
118
0.080
Why?
Species Specificity
1
2011
581
0.080
Why?
Female
12
2025
73763
0.080
Why?
Viruses
1
2011
161
0.070
Why?
Tumor Suppressor Protein p53
1
2013
525
0.070
Why?
Retroviridae
1
2008
103
0.070
Why?
Burns
1
2013
341
0.070
Why?
cdc42 GTP-Binding Protein
2
2006
22
0.070
Why?
Mitochondria
1
2014
955
0.070
Why?
Peptides
2
2011
976
0.070
Why?
Pulmonary Alveoli
1
2011
408
0.070
Why?
Transgenes
1
2008
185
0.070
Why?
Adult
8
2025
38201
0.070
Why?
Kruppel-Like Transcription Factors
1
2008
66
0.070
Why?
Pulmonary Artery
1
2013
1109
0.070
Why?
Bone Marrow
1
2008
299
0.070
Why?
Adaptor Proteins, Vesicular Transport
1
2007
46
0.060
Why?
Endothelium, Vascular
1
2013
935
0.060
Why?
Membrane Glycoproteins
2
2014
499
0.060
Why?
Middle Aged
4
2020
33604
0.060
Why?
Escherichia coli Infections
1
2007
115
0.060
Why?
rhoA GTP-Binding Protein
1
2006
87
0.060
Why?
Cohort Studies
2
2020
5697
0.060
Why?
Cell Culture Techniques
1
2008
364
0.060
Why?
Up-Regulation
3
2006
851
0.060
Why?
Inflammation
5
2022
2850
0.060
Why?
Hydroxyeicosatetraenoic Acids
1
2005
44
0.060
Why?
Respiratory Mucosa
1
2008
322
0.060
Why?
Toll-Like Receptor 4
2
2007
275
0.060
Why?
MAP Kinase Signaling System
1
2007
322
0.060
Why?
DNA
2
2009
1438
0.060
Why?
Dinoprostone
1
2005
191
0.060
Why?
Drug Therapy, Combination
3
2013
1032
0.050
Why?
Membrane Microdomains
1
2004
35
0.050
Why?
Transcription, Genetic
4
2008
1470
0.050
Why?
beta-Cyclodextrins
1
2004
29
0.050
Why?
Inflammation Mediators
2
2011
513
0.050
Why?
Enzyme Precursors
1
2003
15
0.050
Why?
Chemokines, CXC
1
2004
71
0.050
Why?
NF-kappa B
4
2013
678
0.050
Why?
Receptors, CXCR4
1
2004
87
0.050
Why?
Multicenter Studies as Topic
1
2025
320
0.050
Why?
Splicing Factor U2AF
1
2023
17
0.050
Why?
Zymosan
1
2023
66
0.050
Why?
Young Adult
3
2020
13305
0.050
Why?
Drug Evaluation, Preclinical
1
2024
195
0.050
Why?
Myxovirus Resistance Proteins
1
2003
13
0.050
Why?
Mycobacterium avium
1
2023
20
0.050
Why?
Bacterial Load
2
2015
68
0.050
Why?
eIF-2 Kinase
1
2003
31
0.050
Why?
Chemotaxis
1
2023
133
0.050
Why?
STAT1 Transcription Factor
1
2003
71
0.050
Why?
Anti-Inflammatory Agents, Non-Steroidal
2
2002
347
0.050
Why?
Enzyme Activation
4
2008
810
0.050
Why?
Escherichia coli
1
2007
827
0.050
Why?
Phosphoprotein Phosphatases
1
2002
67
0.050
Why?
Risk Factors
1
2016
10252
0.050
Why?
Toll-Like Receptor 2
1
2003
117
0.050
Why?
Macrophages, Alveolar
1
2005
396
0.050
Why?
Interferon Type I
1
2003
141
0.050
Why?
Phosphatidylinositol 3-Kinases
1
2003
368
0.050
Why?
Gene Expression
2
2008
1488
0.040
Why?
STAT3 Transcription Factor
1
2003
201
0.040
Why?
Ciprofloxacin
2
2013
26
0.040
Why?
Transcriptional Activation
2
2013
376
0.040
Why?
Gene Expression Regulation, Enzymologic
1
2002
274
0.040
Why?
Receptors, Cell Surface
1
2003
394
0.040
Why?
Administration, Inhalation
1
2022
595
0.040
Why?
Trans-Activators
1
2003
385
0.040
Why?
Protein-Tyrosine Kinases
1
2003
431
0.040
Why?
Apoptosis
2
2008
2546
0.040
Why?
Clinical Trials as Topic
1
2025
1034
0.040
Why?
Glycolipids
1
2020
42
0.040
Why?
Mice, Knockout
3
2014
3028
0.040
Why?
Complement System Proteins
1
2023
319
0.040
Why?
Aged, 80 and over
1
2011
7677
0.040
Why?
Transforming Growth Factor beta
1
2002
488
0.040
Why?
Time Factors
3
2018
6851
0.040
Why?
British Columbia
1
2018
21
0.040
Why?
Bronchoalveolar Lavage Fluid
2
2015
649
0.040
Why?
Mice, Transgenic
1
2023
2172
0.030
Why?
Chemokine CXCL1
2
2011
76
0.030
Why?
Cell Migration Inhibition
2
2011
17
0.030
Why?
Chemotaxis, Leukocyte
2
2011
141
0.030
Why?
Morbidity
1
2018
322
0.030
Why?
Drug Administration Routes
1
2016
41
0.030
Why?
Imidazoles
3
2002
239
0.030
Why?
RNA Precursors
1
2017
155
0.030
Why?
Mice, Inbred C57BL
4
2011
5798
0.030
Why?
Proteins
1
2002
1006
0.030
Why?
Aged
2
2015
24024
0.030
Why?
DNA-Binding Proteins
1
2003
1471
0.030
Why?
Cathelicidins
1
2015
41
0.030
Why?
Drug Interactions
1
2016
404
0.030
Why?
Drug Monitoring
1
2016
215
0.030
Why?
NADPH Oxidase 2
1
2014
41
0.030
Why?
Predictive Value of Tests
1
2020
2030
0.030
Why?
Respiratory Function Tests
1
2016
561
0.030
Why?
Reproducibility of Results
1
2002
3307
0.030
Why?
Pilot Projects
1
2020
1765
0.030
Why?
Enzyme Inhibitors
3
2002
847
0.030
Why?
Gentamicins
1
2015
52
0.030
Why?
Chronic Disease
2
2015
1805
0.030
Why?
Drug Resistance, Multiple, Bacterial
1
2014
75
0.030
Why?
NADPH Oxidases
1
2014
140
0.030
Why?
Drug Resistance, Bacterial
1
2015
184
0.030
Why?
Recombinant Proteins
2
2011
1352
0.030
Why?
PPAR gamma
1
2014
180
0.030
Why?
Survival Rate
1
2018
1935
0.030
Why?
Asthma
1
2005
1888
0.020
Why?
JNK Mitogen-Activated Protein Kinases
2
2003
159
0.020
Why?
Spleen
1
2015
523
0.020
Why?
Chemokine CCL2
2
2003
116
0.020
Why?
Adenoviridae
1
2013
200
0.020
Why?
Leukocyte Count
1
2013
326
0.020
Why?
Cell Hypoxia
1
2013
230
0.020
Why?
Fibrinogen
1
2013
173
0.020
Why?
Gene Knockdown Techniques
1
2013
329
0.020
Why?
Mutation
1
2023
3987
0.020
Why?
Drug Synergism
1
2013
368
0.020
Why?
Down-Regulation
2
2006
635
0.020
Why?
Neovascularization, Physiologic
1
2013
182
0.020
Why?
Monocytes
1
2014
573
0.020
Why?
Suspensions
1
2011
27
0.020
Why?
Gene Deletion
1
2013
388
0.020
Why?
Chemokine CXCL2
1
2011
42
0.020
Why?
Epithelium, Corneal
1
2011
43
0.020
Why?
Corneal Ulcer
1
2011
21
0.020
Why?
RNA, Small Interfering
1
2013
626
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
2
2003
984
0.020
Why?
Genome
1
2013
299
0.020
Why?
Bacterial Adhesion
1
2011
102
0.020
Why?
Methacrylates
1
2011
117
0.020
Why?
Anti-Infective Agents
1
2013
239
0.020
Why?
Disease Progression
1
2018
2749
0.020
Why?
Cell Adhesion
1
2011
466
0.020
Why?
Rabbits
1
2011
747
0.020
Why?
Prognosis
1
2018
3984
0.020
Why?
Cell Line
2
2008
2876
0.020
Why?
Follow-Up Studies
1
2018
5112
0.020
Why?
Granulocytes
1
2008
85
0.020
Why?
Pyridines
2
2002
494
0.020
Why?
Nitric Oxide
1
2013
893
0.020
Why?
Enzyme Induction
1
2008
90
0.020
Why?
Cystic Fibrosis Transmembrane Conductance Regulator
1
2011
335
0.020
Why?
Colorado
1
2018
4555
0.020
Why?
Acute Lung Injury
1
2011
299
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
1
2008
234
0.020
Why?
Nitric Oxide Synthase Type II
1
2008
174
0.020
Why?
Toll-Like Receptor 3
1
2007
28
0.020
Why?
NF-KappaB Inhibitor alpha
1
2006
50
0.020
Why?
Mitogen-Activated Protein Kinase Kinases
1
2007
132
0.020
Why?
I-kappa B Proteins
1
2006
76
0.020
Why?
Cell Proliferation
1
2013
2480
0.010
Why?
Keratinocytes
1
2007
251
0.010
Why?
Child
2
2020
21921
0.010
Why?
Jurkat Cells
1
2005
138
0.010
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
1
2005
150
0.010
Why?
Cyclodextrins
1
2004
10
0.010
Why?
rac GTP-Binding Proteins
1
2004
36
0.010
Why?
Vital Capacity
1
2005
312
0.010
Why?
Receptors, Interleukin-8B
1
2004
26
0.010
Why?
Syk Kinase
1
2003
21
0.010
Why?
Anthracenes
1
2003
32
0.010
Why?
rho GTP-Binding Proteins
1
2004
60
0.010
Why?
Forced Expiratory Volume
1
2005
488
0.010
Why?
Chemokine CXCL12
1
2004
83
0.010
Why?
Cross-Sectional Studies
1
2015
5520
0.010
Why?
Promoter Regions, Genetic
1
2008
1233
0.010
Why?
Cells, Cultured
1
2011
4181
0.010
Why?
Chemokines
1
2004
226
0.010
Why?
Dexamethasone
1
2005
375
0.010
Why?
DNA Primers
1
2003
508
0.010
Why?
Precipitin Tests
1
2002
98
0.010
Why?
Bone Marrow Cells
1
2004
325
0.010
Why?
Analysis of Variance
1
2005
1317
0.010
Why?
Cholesterol
1
2004
403
0.010
Why?
Protein Phosphatase 2
1
2002
40
0.010
Why?
Intubation, Gastrointestinal
1
2002
77
0.010
Why?
Electrophoresis, Gel, Two-Dimensional
1
2002
112
0.010
Why?
Aminopyridines
1
2002
102
0.010
Why?
Cell Survival
1
2005
1123
0.010
Why?
Ligands
1
2004
665
0.010
Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
1
2002
144
0.010
Why?
Anti-Inflammatory Agents
1
2005
476
0.010
Why?
Transcription Factor AP-1
1
2002
88
0.010
Why?
Epithelial Cells
1
2008
1102
0.010
Why?
Cell Differentiation
1
2008
1992
0.010
Why?
Adolescent
1
2020
21564
0.010
Why?
Intracellular Signaling Peptides and Proteins
1
2003
462
0.010
Why?
Drug Administration Schedule
1
2002
768
0.010
Why?
Homeostasis
1
2004
614
0.010
Why?
In Vitro Techniques
1
2002
1092
0.010
Why?
Base Sequence
1
2003
2174
0.010
Why?
Amino Acid Sequence
1
2002
2155
0.010
Why?
Proteome
1
2002
469
0.010
Why?
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