 Tobramycin
"Tobramycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the PSEUDOMONAS species. It is a 10% component of the antibiotic complex, NEBRAMYCIN, produced by the same species.
| Descriptor ID |
D014031
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| MeSH Number(s) |
D09.408.051.476.600.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tobramycin".
Below are MeSH descriptors whose meaning is more specific than "Tobramycin".
This graph shows the total number of publications written about "Tobramycin" by people in this website by year, and whether "Tobramycin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2007 | 1 | 1 | 2 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 2 | 3 | | 2016 | 1 | 1 | 2 | | 2018 | 0 | 2 | 2 | | 2019 | 2 | 0 | 2 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2025 | 1 | 0 | 1 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tobramycin" by people in Profiles.
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O'Toole RV, O'Hara NN, Carlini AR, Schrank GM, Chung S, Gary JL, Obremskey W, Matuszewski PE, Teague D, Natoli RM, Gitajn IL, Weaver MJ, Renninger CH, Levack AE, Degani Y, Collins SC, Weston-Farber E, Howe AL, Thompson RE, Castillo RC, Karunakar MA, Blum L, Harmer L, Hsu JR, Kempton LB, Phelps KD, Seymour RB, Sims SH, Acharya MS, Callahan H, Chavez-Araujo LM, Churchill C, Gambuzza MP, Haim KR, Ishman E, Kendall JS, Mullis ND, Young C, Pilson HT, Carroll EA, Goodman JB, Holden MB, Jones AL, Moon C, Lin CA, Marecek GS, Moffitt GB, Conlan T, George AV, Fisher LA, Mullin DS, Recendez CL, Aneja A, Brameier DT, Heng M, Ly TV, Stenquist DS, Suneja N, Wignakumar T, Borgida JS, Policicchio TJ, Hanson GR, Alese OM, Ricci WM, Behrens SB, Dvorzhinskiy A, Bilodeau RE, Klinger CE, Mullis BH, Jang Y, Lopas LA, McKinley TO, O'Neill DC, Szatkowski JP, Virkus WW, Hill LC, Gaski G, Hymes RA, Ahn J, Goch AM, Holzman M, Malekzadeh AS, Schulman JE, Rivera JC, Krause PC, Bridgman C, Cohen J, Eikani C, Chavez M, Kudulis M, Warner SJ, Achor TS, Choo A, Eastman JG, Kellam PJ, Boutte SJ, Guevara KD, Reid KR, Vallier HA, Tucci AV, Davis JM, Bell AC, Bonyun ME, Healey K, Li V, McKibben NS, Nascone J, Okhuereigbe D, Sciadini MF, Slobogean G, Zingas N, Kovvur M, Lawrence JE, Phipps H, Rudnicki J, Turner KE, Hayda R, Evans AR, Quinnan S, Benitez A, Rehman S, Soderquist MC, Townsend CB, Caroom C, Collins AC, Okwumabua E, Shaikh HS, Spitler CA, Agarwal A, Johnson MD, Haller JM, Marchand LS, Alfonso NA, Gorman MA, Charlton WM, Scott BR, Kraus KM, Meredith SJ, Talwar S, Bergin PF, Jha AJ, McGee S, Nehete PV, Pryor TA, Spears I, Chen AT, Kelley B, Nez NR, Ertl WJ, Hull BR, Blumenthal S, Patterson JT, Flynn C, Ross RC, Agarwal A, Weiss DB, Hadeed MM, Yarboro SR, Daoud T, McVey ED, Whiting PS, Domes C, Goodspeed DC, Kuhn GR, Boyce R, Libos A, Mitchell PM, Moreno-Diaz AF, Ponce RB, Stinner DJ, Tatman LM, Velasco-Castro J, Trochez K, Satpathy J, Zuelzer DA, Potter BK. Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures: The TOBRA Randomized Clinical Trial. JAMA. 2026 May 12; 335(18):1586-1595.
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Sajid MI, Grayson W, John MP, Taylor S, Lauck BJ, Zaidi Z, Savage A, Griffin N, Awad M, Chen AT, Hwang J, Alfonso N, Mir HR. Efficacy of Topical Antibiotic Powder Application in the Emergency Department on Reducing Deep Fracture-Related Infection in Type III Open Lower Extremity Fractures: A Multicenter Study. J Am Acad Orthop Surg. 2025 Dec 15; 33(24):e1489-e1496.
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Pesante BD, Parry JA. The Effect of Vancomycin and Tobramycin Local Antibiotic Powder on Surgical Site Infections After Open Treatment of Fracture: A Retrospective Propensity-Matched Analysis. J Orthop Trauma. 2024 04 01; 38(4):177-182.
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Wagner BD, Zemanick ET, Sagel SD, Robertson CE, Stevens MJ, Mayer-Hamblett N, Retsch-Bogart G, Ramsey BW, Harris JK. Limited effects of azithromycin on the oropharyngeal microbiome in children with CF and early pseudomonas infection. BMC Microbiol. 2023 10 27; 23(1):312.
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Liu SH, Saldanha IJ, Abraham AG, Rittiphairoj T, Hauswirth S, Gregory D, Ifantides C, Li T. Topical corticosteroids for dry eye. Cochrane Database Syst Rev. 2022 10 21; 10:CD015070.
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Nichols DP, Singh PK, Baines A, Caverly LJ, Chmiel JF, GIbson RL, Lascano J, Morgan SJ, Retsch-Bogart G, Saiman L, Sadeghi H, Billings JL, Heltshe SL, Kirby S, Kong A, Nick JA, Mayer-Hamblett N. Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial. Thorax. 2022 06; 77(6):581-588.
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Saad A, Young MR, Studtmann AE, Autry EB, Schadler A, Beckman EJ, Gardner BM, Wurth MA, Kuhn RJ. Incidence of nephrotoxicity with prolonged aminoglycoside exposure in patients with cystic fibrosis. Pediatr Pulmonol. 2020 12; 55(12):3384-3390.
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Downs AM, Gerson J, Ploense KL, Plaxco KW, Dauphin-Ducharme P. Subsecond-Resolved Molecular Measurements Using Electrochemical Phase Interrogation of Aptamer-Based Sensors. Anal Chem. 2020 10 20; 92(20):14063-14068.
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Jewell MP, Saccomano SC, David AA, Harris JK, Zemanick ET, Cash KJ. Nanodiagnostics to monitor biofilm oxygen metabolism for antibiotic susceptibility testing. Analyst. 2020 Jun 07; 145(11):3996-4003.
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Amison RT, Faure ME, O'Shaughnessy BG, Bruce KD, Hu Y, Coates A, Page CP. The small quinolone derived compound HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. Pulm Pharmacol Ther. 2020 04; 61:101884.
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