 cdc42 GTP-Binding Protein
"cdc42 GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the Rho family of MONOMERIC GTP-BINDING PROTEINS. It is associated with a diverse array of cellular functions including cytoskeletal changes, filopodia formation and transport through the GOLGI APPARATUS. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020764
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| MeSH Number(s) |
D08.811.277.040.330.300.400.700.050 D12.644.360.525.700.050 D12.776.157.325.515.700.050 D12.776.476.525.700.050
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| Concept/Terms |
cdc42 GTP-Binding Protein- cdc42 GTP-Binding Protein
- GTP-Binding Protein, cdc42
- cdc42 GTP Binding Protein
- p21 cdc42
- cdc42, p21
- cdc42 Protein
- G25K Protein
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Below are MeSH descriptors whose meaning is more general than "cdc42 GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "cdc42 GTP-Binding Protein".
This graph shows the total number of publications written about "cdc42 GTP-Binding Protein" by people in this website by year, and whether "cdc42 GTP-Binding Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1997 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2004 | 2 | 1 | 3 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "cdc42 GTP-Binding Protein" by people in Profiles.
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Althoff MJ, Nayak RC, Hegde S, Wellendorf AM, Bohan B, Filippi MD, Xin M, Lu QR, Geiger H, Zheng Y, Diaz-Meco MT, Moscat J, Cancelas JA. Yap1-Scribble polarization is required for hematopoietic stem cell division and fate. Blood. 2020 10 15; 136(16):1824-1836.
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Jansson T, Castillo-Castrejon M, Gupta MB, Powell TL, Rosario FJ. Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction. Clin Sci (Lond). 2020 01 17; 134(1):53-70.
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Martinelli S, Krumbach OHF, Pantaleoni F, Coppola S, Amin E, Pannone L, Nouri K, Farina L, Dvorsky R, Lepri F, Buchholzer M, Konopatzki R, Walsh L, Payne K, Pierpont ME, Vergano SS, Langley KG, Larsen D, Farwell KD, Tang S, Mroske C, Gallotta I, Di Schiavi E, Della Monica M, Lugli L, Rossi C, Seri M, Cocchi G, Henderson L, Baskin B, Alders M, Mendoza-Londono R, Dupuis L, Nickerson DA, Chong JX, Meeks N, Brown K, Causey T, Cho MT, Demuth S, Digilio MC, Gelb BD, Bamshad MJ, Zenker M, Ahmadian MR, Hennekam RC, Tartaglia M, Mirzaa GM. Functional Dysregulation of CDC42 Causes Diverse Developmental Phenotypes. Am J Hum Genet. 2018 02 01; 102(2):309-320.
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Guo Y, Kenney SR, Muller CY, Adams S, Rutledge T, Romero E, Murray-Krezan C, Prekeris R, Sklar LA, Hudson LG, Wandinger-Ness A. R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis. Mol Cancer Ther. 2015 Oct; 14(10):2215-27.
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Yuan K, Orcholski ME, Panaroni C, Shuffle EM, Huang NF, Jiang X, Tian W, Vladar EK, Wang L, Nicolls MR, Wu JY, de Jesus Perez VA. Activation of the Wnt/planar cell polarity pathway is required for pericyte recruitment during pulmonary angiogenesis. Am J Pathol. 2015 Jan; 185(1):69-84.
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Moorman VR, Valentine KG, B?dard S, Kasinath V, Dogan J, Love FM, Wand AJ. Dynamic and thermodynamic response of the Ras protein Cdc42Hs upon association with the effector domain of PAK3. J Mol Biol. 2014 Oct 23; 426(21):3520-38.
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Chen HY, Yang YM, Stevens BM, Noble M. Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells. EMBO Mol Med. 2013 May; 5(5):723-36.
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Keestra AM, Winter MG, Auburger JJ, Fr?ssle SP, Xavier MN, Winter SE, Kim A, Poon V, Ravesloot MM, Waldenmaier JF, Tsolis RM, Eigenheer RA, B?umler AJ. Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. Nature. 2013 Apr 11; 496(7444):233-7.
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Flannagan RS, Jaumouill? V, Huynh KK, Plumb JD, Downey GP, Valvano MA, Grinstein S. Burkholderia cenocepacia disrupts host cell actin cytoskeleton by inactivating Rac and Cdc42. Cell Microbiol. 2012 Feb; 14(2):239-54.
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Roney KE, O'Connor BP, Wen H, Holl EK, Guthrie EH, Davis BK, Jones SW, Jha S, Sharek L, Garcia-Mata R, Bear JE, Ting JP. Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. PLoS One. 2011; 6(9):e24795.
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