Fibrinogen
"Fibrinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Descriptor ID |
D005340
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MeSH Number(s) |
D12.776.124.050.250 D12.776.124.125.500 D12.776.811.300 D23.119.490
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Concept/Terms |
Fibrinogen- Fibrinogen
- Blood Coagulation Factor I
- Coagulation Factor I
- Factor I, Coagulation
- Factor I
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Below are MeSH descriptors whose meaning is more general than "Fibrinogen".
Below are MeSH descriptors whose meaning is more specific than "Fibrinogen".
This graph shows the total number of publications written about "Fibrinogen" by people in this website by year, and whether "Fibrinogen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 2 | 3 | 1996 | 0 | 1 | 1 | 1997 | 1 | 0 | 1 | 1998 | 0 | 2 | 2 | 1999 | 1 | 1 | 2 | 2000 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2004 | 1 | 1 | 2 | 2005 | 2 | 0 | 2 | 2006 | 0 | 2 | 2 | 2007 | 2 | 2 | 4 | 2008 | 2 | 2 | 4 | 2009 | 1 | 2 | 3 | 2010 | 6 | 4 | 10 | 2011 | 1 | 1 | 2 | 2012 | 4 | 3 | 7 | 2013 | 4 | 3 | 7 | 2014 | 5 | 1 | 6 | 2015 | 3 | 3 | 6 | 2017 | 1 | 4 | 5 | 2018 | 1 | 2 | 3 | 2019 | 4 | 10 | 14 | 2020 | 0 | 1 | 1 | 2021 | 2 | 2 | 4 | 2022 | 0 | 3 | 3 | 2023 | 1 | 4 | 5 |
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Below are the most recent publications written about "Fibrinogen" by people in Profiles.
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Richardson LA, Basu A, Chien LC, Alman AC, Snell-Bergeon JK. Longitudinal associations of physical activity with inflammatory markers in US adults with and without type 1 diabetes. Diabetes Res Clin Pract. 2023 Dec; 206:110978.
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Poole LG, Schmitt LR, Schulte A, Groeneveld DJ, Cline HM, Sang Y, Hur WS, Wolberg AS, Flick MJ, Hansen KC, Luyendyk JP. Altered fibrinogen ?-chain cross-linking in mutant fibrinogen-??5 mice drives acute liver injury. J Thromb Haemost. 2023 08; 21(8):2175-2188.
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Staats A, Burback PW, Casillas-Ituarte NN, Li D, Hostetler MR, Sullivan A, Horswill AR, Lower SK, Stoodley P. In Vitro Staphylococcal Aggregate Morphology and Protection from Antibiotics Are Dependent on Distinct Mechanisms Arising from Postsurgical Joint Components and Fluid Motion. J Bacteriol. 2023 04 25; 205(4):e0045122.
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Warren BB, Moyer GC, Manco-Johnson MJ. Hemostasis in the Pregnant Woman, the Placenta, the Fetus, and the Newborn Infant. Semin Thromb Hemost. 2023 Jun; 49(4):319-329.
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DeBot M, Erickson C, Kelher M, Schaid TR, Moore EE, Sauaia A, Cralley A, LaCroix I, D'Alessandro A, Hansen K, Cohen MJ, Silliman CC, Coleman J. Platelet and cryoprecipitate transfusions from female donors improve coagulopathy in vitro. J Trauma Acute Care Surg. 2023 04 01; 94(4):497-503.
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Coleman JR, Fabbri S, Anderson M, Moore EE, Cohen MJ, Hadley J, Ghasabyan A, Chandler J, Kelher M, Freeman K, Miller ZD, Silliman CC. Beyond uterine atony: characterizing postpartum hemorrhage coagulopathy. Am J Obstet Gynecol MFM. 2023 03; 5(3):100822.
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Coleman JR, Moore EE, Schmitt L, Hansen K, Dow N, Freeman K, Cohen MJ, Silliman CC. Estradiol provokes hypercoagulability and affects fibrin biology: A mechanistic exploration of sex dimorphisms in coagulation. J Trauma Acute Care Surg. 2023 02 01; 94(2):179-186.
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Marin AI, Poppelaars F, Wagner BD, Palestine AG, Patnaik JL, Holers VM, Frazer-Abel AA, Mathias MT, Manoharan N, Fonteh CN, Mandava N, Lynch AM. Sex and Age-Related Differences in Complement Factors Among Patients With Intermediate Age-Related Macular Degeneration. Transl Vis Sci Technol. 2022 05 02; 11(5):22.
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Thibord F, Song C, Pattee J, Rodriguez BAT, Chen MH, O'Donnell CJ, Kleber ME, Delgado GE, Guo X, Yao J, Taylor KD, Ozel AB, Brody JA, McKnight B, Gyorgy B, Simonsick E, Leonard HL, Carrasquilla GD, Guindo-Martinez M, Silveira A, Temprano-Sagrera G, Yanek LR, Becker DM, Mathias RA, Becker LC, Raffield LM, Kilpel?inen TO, Grarup N, Pedersen O, Hansen T, Linneberg A, Hamsten A, Watkins H, Sabater-Lleal M, Nalls MA, Tr?gou?t DA, Morange PE, Psaty BM, Tracy RP, Smith NL, Desch KC, Cushman M, Rotter JI, de Vries PS, Pankratz ND, Folsom AR, Morrison AC, M?rz W, Tang W, Johnson AD. FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer. J Thromb Haemost. 2021 08; 19(8):2019-2028.
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Jarrell DK, Vanderslice EJ, Lennon ML, Lyons AC, VeDepo MC, Jacot JG. Increasing salinity of fibrinogen solvent generates stable fibrin hydrogels for cell delivery or tissue engineering. PLoS One. 2021; 16(5):e0239242.
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