 Fibrinogen
"Fibrinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
| Descriptor ID |
D005340
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| MeSH Number(s) |
D12.776.124.050.250 D12.776.124.125.500 D12.776.811.300 D23.119.490
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| Concept/Terms |
Fibrinogen- Fibrinogen
- Blood Coagulation Factor I
- Coagulation Factor I
- Factor I, Coagulation
- Factor I
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Below are MeSH descriptors whose meaning is more general than "Fibrinogen".
Below are MeSH descriptors whose meaning is more specific than "Fibrinogen".
This graph shows the total number of publications written about "Fibrinogen" by people in this website by year, and whether "Fibrinogen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 2 | 2 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 2 | 3 | | 2005 | 2 | 0 | 2 | | 2006 | 0 | 2 | 2 | | 2007 | 2 | 2 | 4 | | 2008 | 2 | 2 | 4 | | 2009 | 1 | 2 | 3 | | 2010 | 6 | 4 | 10 | | 2011 | 1 | 1 | 2 | | 2012 | 4 | 3 | 7 | | 2013 | 3 | 3 | 6 | | 2014 | 5 | 2 | 7 | | 2015 | 2 | 3 | 5 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 4 | 5 | | 2018 | 1 | 1 | 2 | | 2019 | 5 | 8 | 13 | | 2020 | 0 | 1 | 1 | | 2021 | 2 | 3 | 5 | | 2022 | 1 | 2 | 3 | | 2023 | 1 | 5 | 6 | | 2024 | 1 | 2 | 3 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fibrinogen" by people in Profiles.
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Wei Z, Boateng NKK, Schmitt LR, Cline H, Fernandes Fonseca MT, Newberry A, Taylor A, Adelmeijer J, Poole LG, Stravitz RT, Lee WM, Lisman T, Hansen KC, Luyendyk JP. Integrated cross-linking by TG2 and FXIII generates hepatoprotective fibrin(ogen) deposits in injured liver. Blood. 2025 May 22; 145(21):2507-2517.
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Huffman JE, Nicholas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, Bielak LF, Bowler RP, Carrasquilla GD, Chasman DI, Chen MH, Emmert DB, Ghanbari M, Haessler J, Hottenga JJ, Kleber ME, Le NQ, Lee J, Lewis JP, Li-Gao R, Luan J, Malmberg A, Mangino M, Marioni RE, Martinez-Perez A, Pankratz N, Polasek O, Richmond A, Rodriguez BAT, Rotter JI, Steri M, Suchon P, Trompet S, Weiss S, Zare M, Auer P, Cho MH, Christofidou P, Davies G, de Geus E, Deleuze JF, Delgado GE, Ekunwe L, Faraday N, G?gele M, Greinacher A, Gao H, Howard T, Joshi PK, Kilpel?inen TO, Lahti J, Linneberg A, Naitza S, Noordam R, Pa?ls-Verg?s F, Rich SS, Rosendaal FR, Rudan I, Ryan KA, Souto JC, van Rooij FJA, Wang H, Zhao W, Becker LC, Beswick A, Brown MR, Cade BE, Campbell H, Cho K, Crapo JD, Curran JE, de Maat MPM, Doyle M, Elliott P, Floyd JS, Fuchsberger C, Grarup N, Guo X, Harris SE, Hou L, Kolcic I, Kooperberg C, Menni C, Nauck M, O'Connell JR, Orr? V, Psaty BM, R?ikk?nen K, Smith JA, Soria JM, Stott DJ, van Hylckama Vlieg A, Watkins H, Willemsen G, Wilson PWF, Ben-Shlomo Y, Blangero J, Boomsma D, Cox SR, Dehghan A, Eriksson JG, Fiorillo E, Fornage M, Hansen T, Hayward C, Ikram MA, Jukema JW, Kardia SLR, Lange LA, M?rz W, Mathias RA, Mitchell BD, Mook-Kanamori DO, Morange PE, Pedersen O, Pramstaller PP, Redline S, Reiner A, Ridker PM, Silverman EK, Spector TD, V?lker U, Wareham NJ, Wilson JF, Yao J, Tr?gou?t DA, Johnson AD, Wolberg AS, de Vries PS, Sabater-Lleal M, Morrison AC, Smith NL. Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles. Blood. 2024 Nov 21; 144(21):2248-2265.
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Rosenthal CA, Douin DJ, Cohen MJ, Rizzo JA, April MD, Schauer SG. Characterising practice patterns of human derived, lyophilized coagulation concentrates within the trauma quality improvement program registry. Transfus Med. 2024 Dec; 34(6):520-526.
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Adkins BD, Noland DK, Jacobs JW, Booth GS, Malicki D, Helander L, Jacquot C, Buscema G, Goel R, Andrews J, Lieberman L. Survey of pediatric massive transfusion protocol practice at United States level I trauma centers: An AABB Pediatric Transfusion Medicine Subsection study. Transfusion. 2024 Oct; 64(10):1860-1869.
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Thomas KA, Rassam RMG, Kar R, Dishong DM, Rahn KC, Fonseca R, Canas M, Aldana J, Afzal H, Bochicchio K, Neal MD, Bochicchio GV, Spinella PC, Shea SM. Trauma patients have reduced ex vivo flow-dependent platelet hemostatic capacity in a microfluidic model of vessel injury. PLoS One. 2024; 19(7):e0304231.
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Richardson LA, Basu A, Chien LC, Alman AC, Snell-Bergeon JK. Longitudinal associations of physical activity with inflammatory markers in US adults with and without type 1 diabetes. Diabetes Res Clin Pract. 2023 Dec; 206:110978.
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White NJ, Asato C, Wenthe A, Wang X, Ringgold K, St John A, Han CY, Bennett JC, Stern SA. Slow Intravenous Infusion of a Novel Damage Control Cocktail Decreases Blood Loss in a Pig Polytrauma Model. J Spec Oper Med. 2023 Oct 05; 23(3):50-57.
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Poole LG, Schmitt LR, Schulte A, Groeneveld DJ, Cline HM, Sang Y, Hur WS, Wolberg AS, Flick MJ, Hansen KC, Luyendyk JP. Altered fibrinogen ?-chain cross-linking in mutant fibrinogen-??5 mice drives acute liver injury. J Thromb Haemost. 2023 08; 21(8):2175-2188.
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Staats A, Burback PW, Casillas-Ituarte NN, Li D, Hostetler MR, Sullivan A, Horswill AR, Lower SK, Stoodley P. In Vitro Staphylococcal Aggregate Morphology and Protection from Antibiotics Are Dependent on Distinct Mechanisms Arising from Postsurgical Joint Components and Fluid Motion. J Bacteriol. 2023 04 25; 205(4):e0045122.
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Warren BB, Moyer GC, Manco-Johnson MJ. Hemostasis in the Pregnant Woman, the Placenta, the Fetus, and the Newborn Infant. Semin Thromb Hemost. 2023 Jun; 49(4):319-329.
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