 Clinical Trials as Topic
"Clinical Trials as Topic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
| Descriptor ID |
D002986
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| MeSH Number(s) |
E05.318.760.250.500 N05.715.360.775.088.500 N06.850.520.450.250.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clinical Trials as Topic".
Below are MeSH descriptors whose meaning is more specific than "Clinical Trials as Topic".
This graph shows the total number of publications written about "Clinical Trials as Topic" by people in this website by year, and whether "Clinical Trials as Topic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 8 | 10 | | 1996 | 1 | 7 | 8 | | 1997 | 2 | 12 | 14 | | 1998 | 0 | 8 | 8 | | 1999 | 0 | 11 | 11 | | 2000 | 0 | 11 | 11 | | 2001 | 1 | 18 | 19 | | 2002 | 3 | 23 | 26 | | 2003 | 2 | 22 | 24 | | 2004 | 2 | 22 | 24 | | 2005 | 5 | 31 | 36 | | 2006 | 6 | 17 | 23 | | 2007 | 7 | 23 | 30 | | 2008 | 8 | 23 | 31 | | 2009 | 13 | 23 | 36 | | 2010 | 8 | 27 | 35 | | 2011 | 12 | 28 | 40 | | 2012 | 12 | 21 | 33 | | 2013 | 10 | 19 | 29 | | 2014 | 5 | 23 | 28 | | 2015 | 7 | 26 | 33 | | 2016 | 8 | 29 | 37 | | 2017 | 14 | 28 | 42 | | 2018 | 15 | 23 | 38 | | 2019 | 8 | 32 | 40 | | 2020 | 12 | 33 | 45 | | 2021 | 12 | 17 | 29 | | 2022 | 3 | 20 | 23 | | 2023 | 0 | 9 | 9 | | 2024 | 11 | 23 | 34 | | 2025 | 11 | 8 | 19 |
To return to the timeline, click here.
Below are the most recent publications written about "Clinical Trials as Topic" by people in Profiles.
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Igudesman D, Nally LM, Grimshaw AA, Gunderson CG, Considine EG, Jacobsen LM, Tosur M, Gottlieb PA, Hirsch IB, Laffel LM, Sherr JL, Mathieu C, Pratley RE. Dietary Patterns for Weight and Glycemic Management in Persons With Type 1 Diabetes: A Meta-analysis of Clinical Trials. J Clin Endocrinol Metab. 2025 Oct 16; 110(11):3289-3300.
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van den Bent MJ, Vogelbaum MA, Cloughesy T, Galldiks N, Albert NL, Tonn JC, Avila E, Fangusaro J, Mirsky D, Sahgal A, Soffietti R, Karschnia P, Mehta M, Kim MM, Boele F, Huse JT, Nayak L, Lim-Fat MJ, le Rhun E, Desjardins A, Lee EQ, Chukwueke U, Koekkoek JAF, Mendoza T, Loughan AR, Budhu JA, Bakas S, Huang RY, Villanueva-Meyer JE, Leone JP, Okada H, Reardon DA, Bi WL, Wen PY, Chang SM. Response Assessment in Neuro-Oncology (RANO) 2009-2025: Broad scope and implementation-A progress report. Neuro Oncol. 2025 Oct 14; 27(9):2209-2224.
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Price SN, Land SR, Pebley K, Fahey MC, Palmer AM, McCall MH, Raper PJ, Rojewski AM, Croghan IT, Wagner LI, Toll BA. Tobacco Assessment in Actively Accruing National Cancer Institute Clinical Trials Network Trials. Nicotine Tob Res. 2025 Sep 23; 27(10):1739-1749.
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Jurgens SJ, Melloni GEM, Kany S, Fabritz L, Rämö JT, Goette A, Kamanu FK, Berg DD, Magnussen C, Choi SH, Bonaca MP, Giugliano RP, Scirica BM, Wiviott SD, Bhatt DL, Steg PG, Raz I, Braunwald E, Pirruccello JP, Sabatine MS, Marston NA, Kirchhof P, Ellinor PT, Ruff CT. Pathogenic Cardiomyopathy-Associated Gene Variants and Prognosis in Atrial Fibrillation: Results in 18,000 Clinical Trial Participants. J Am Coll Cardiol. 2025 Sep 09; 86(10):738-753.
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Zane LK, Yee LM, Chang TC, Sklar J, Yang G, Wen JD, Li P, Harrington R, Sims DJ, Harper K, Trent JM, LoBello JR, Szelinger S, Benson K, Zeng J, Poorman K, Xu D, Frampton GM, Pavlick DC, Miller VA, Tandon B, Swat W, Weiss L, Funari VA, Conroy JM, Prescott JL, Chandra PK, Ma C, Champion KJ, Baschkopf GX, Fesko YA, Freitas TAK, Tomlins SA, Hovelson DH, White K, Sorrells S, Tell R, Beaubier N, King D, Li L, Kelly K, Uvalic J, Meyers B, Kolhe R, Lindeman NI, Baltay M, Sholl LM, Lopategui J, Vail E, Zhang W, Telatar M, Afkhami M, Hsiao SJ, Mansukhani MM, Adams E, Jiang L, Aldape KD, Raffeld M, Xi L, Stehr H, Segal JP, Aisner DL, Davies KD, Brown NA, Livingston RJ, Konnick EQ, Song W, Solomon JP, Walther Z, McShane LM, Harris LN, Chen AP, Tsongalis GJ, Hamilton SR, Flaherty KT, O'Dwyer PJ, Conley BA, Patton DR, Iafrate AJ, Williams PM, Tricoli JV, Karlovich C. A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial. Clin Cancer Res. 2025 Aug 14; 31(16):3512-3525.
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Haskell-Mendoza AP, Gonzalez AT, Reason EH, Jackson JD, Seas A, Mohan AA, Zaidi SE, Lerner EC, Srinivasan ES, Bradbury C, Herndon JE, Goodwin CR, Fecci PE. Disparities in clinical trial enrollment related to laser interstitial thermal therapy for central nervous system metastases. Neurosurg Rev. 2025 Jul 22; 48(1):575.
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Pearson AD, Chi S, Laetscht TW, Marshall L, Raetz E, George RE, Chesler L, Karres D, Scobie N, Knoderer H, Weigel B, Teachey D, Sonke GS, Seibel N, Pappo A, Nysom K, Muscal J, Molenaar J, McDonough J, Macy ME, Ludwinski D, Lin C, Ligas F, Lesa G, Knox L, Kirschbaum M, Kieran M, Kholmanskikh O, Jacobson A, Heenen D, Hawkins DS, Glade Bender J, Fox E, Demolis P, de Rojas T, Cox MC, Chauvin B, Blanc P, Vassal G. Paediatric strategy forum for medicinal product development of cyclin-dependent kinase inhibitors in children and adolescents ACCELERATE in collaboration with the European Medicines Agency With participation of the Food and Drug Administration. Eur J Cancer. 2025 Aug 26; 226:115629.
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Benedetti DJ, Cost NG, Ehrlich PF, Evageliou N, Fialkowski E, Parsons LN, Vallance KL, Renfro LA, Hong AL, Aldrink JH, Pater L, Paulino AC, Sandberg JK, Smith EA, Treece AL, Dome JS, Geller JI, Mullen EA. Updated favourable-histology Wilms tumour risk stratification: rationale for future Children's Oncology Group clinical trials. Nat Rev Urol. 2025 Nov; 22(11):775-788.
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Mehari M, Warrier G, Dada A, Kabir A, Haskell-Mendoza AP, Tripathy A, Jha R, Nieblas-Bedolla E, Jackson JD, Gonzalez AT, Reason EH, Flusche AM, Reihl S, Dalton T, Negussie M, Gonzales CN, Ambati VS, Desjardins A, Daniel AGS, Krishna S, Chang S, Porter A, Fecci PE, Hollon T, Chukwueke UN, Badal K, Molinaro AM, Hervey-Jumper SL. Predicting therapeutic clinical trial enrollment for adult patients with low- and high-grade glioma using supervised machine learning. Sci Adv. 2025 Jun 06; 11(23):eadt5708.
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Major A, Dueck AC, Thanarajasingam G. Beyond maximum grade: advancing the measurement and analysis of adverse events in malignant haematology trials in the modern era. Lancet Haematol. 2025 Jun; 12(6):e451-e462.
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