 Sputum
"Sputum" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Material coughed up from the lungs and expectorated via the mouth. It contains MUCUS, cellular debris, and microorganisms. It may also contain blood or pus.
| Descriptor ID |
D013183
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| MeSH Number(s) |
A12.200.808
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| Concept/Terms |
Sputum, Induced- Sputum, Induced
- Induced Sputum
- Induced Sputums
- Sputums, Induced
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Below are MeSH descriptors whose meaning is more general than "Sputum".
Below are MeSH descriptors whose meaning is more specific than "Sputum".
This graph shows the total number of publications written about "Sputum" by people in this website by year, and whether "Sputum" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 1 | 5 | 6 | | 2003 | 3 | 1 | 4 | | 2004 | 3 | 6 | 9 | | 2005 | 2 | 2 | 4 | | 2006 | 2 | 5 | 7 | | 2007 | 2 | 2 | 4 | | 2008 | 1 | 2 | 3 | | 2009 | 2 | 1 | 3 | | 2010 | 4 | 1 | 5 | | 2011 | 3 | 2 | 5 | | 2012 | 3 | 5 | 8 | | 2013 | 4 | 3 | 7 | | 2014 | 3 | 6 | 9 | | 2015 | 3 | 7 | 10 | | 2016 | 3 | 8 | 11 | | 2017 | 5 | 8 | 13 | | 2018 | 1 | 7 | 8 | | 2019 | 4 | 7 | 11 | | 2020 | 0 | 11 | 11 | | 2021 | 3 | 3 | 6 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 4 | 4 | | 2024 | 2 | 4 | 6 | | 2025 | 2 | 7 | 9 | | 2026 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Sputum" by people in Profiles.
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Sagel SD, Poore TS, Wagner BD, Xie J, Heltshe SL, Cross M, Bratcher PE, Taylor-Cousar JL, Wilson A, McBennett K, Morgan SJ, Singh PK, Nichols DP, Kelly A, Solomon GM. Long-term reductions in inflammation in people with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor. Ann Am Thorac Soc. 2026 Feb 01; 23(2):241-251.
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Lihou K, McGuinness S, Morales-Aza B, Begier E, Duale K, Aldridge R, Farhoudi N, Vowles J, Thomas D, Southern J, Oliver J, Lahuerta M, Schneider K, Gessner BD, Finn A, Danon L, Hyams C. Sensitivity of RSV detection by PCR in respiratory samples is not reduced by a 24?h delay from sampling to testing with storage at room temperature. Mol Med. 2025 Nov 22; 31(1):342.
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Knoll RL, Brauny MM, Robert E, Cloos L, Waser L, Hilbert K, Ulmer N, Hillen B, Birkner T, Bartolomaeus TUP, Nitsche O, Jarquín-Díaz VH, Lynch S, Gehring S, Maier L, Poplawska K, Forslund-Startceva SK. CFTR modulator therapy drives microbiome restructuring through improved host physiology in cystic fibrosis: the IMMProveCF phase IV trial. Nat Commun. 2025 Nov 18; 16(1):10111.
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Pittman JE, Morgan S, McCreary M, Vu PT, Jorth P, Heltshe S, Hoffman LR, Kelly A, Sagel SD, Singh PK, Solomon GM, Rosenfeld M, Ratjen F. Clinical Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in 6- to 11-Year-Olds with Cystic Fibrosis: An Observational Study. Ann Am Thorac Soc. 2025 Nov; 22(11):1696-1708.
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Shi J, Yu C, Ke D, Yuan X, Pang Y, Wu Y, Wang T, Stultz R, Liu X, Tian X, Li M, Wang Q, Demoruelle MK, Solomon JJ, Lood C. Systemic neutrophil activation and N-formyl methionine-formyl peptide receptor-1 signaling define inflammatory endotypes in rheumatoid arthritis-associated lung involvement. J Intern Med. 2025 Dec; 298(6):656-669.
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Sun L, Walls SA, Dang H, Quinney NL, Sears PR, Sadritabrizi T, Hasegawa K, Okuda K, Asakura T, Chang X, Zheng M, Mikami Y, Dizmond FU, Danilova D, Zhou L, Deshmukh A, Cholon DM, Radicioni G, Rogers TD, Kissner WJ, Markovetz MR, Guhr Lee TN, Gutay MI, Esther CR, Chua M, Grubb BR, Ehre C, Kesimer M, Hill DB, Ostrowski LE, Button B, Gentzsch M, Robinson C, Olivier KN, Freeman AF, Randell SH, Vladar E, O'Neal WK, Boucher RC, Chen G. STAT3-Dependent Regulation of CFTR and Ciliogenesis Is Essential for Mucociliary Clearance and Innate Airway Defense in Hyper-IgE Syndrome. Am J Respir Crit Care Med. 2025 Oct; 211(10):1951-1969.
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Hoppe JE, Vigers T, Trujillo A, Hanley E, Sagel SD, Zemanick ET. Impact of Home Collection and Shipping of Respiratory Specimens on Bacterial Pathogen Detection in Children With Cystic Fibrosis. Pediatr Pulmonol. 2025 Sep; 60(9):e71289.
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Singh S, Gumbo T, Wang JY, Boorgula GD, Burke A, Huang HL, McShane PJ, Amaro-Galvez R, Gross JE, Aryal S, Heysell SK, Srivastava S. Imipenem Pharmacokinetics/Pharmacodynamics in Preclinical Hollow Fiber Model, Dose Finding in Virtual Patients, and Clinical Evidence of Efficacy for Mycobacterium abscessus Lung Disease. J Infect Dis. 2025 Jul 11; 231(6):1521-1531.
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Wilson TM, Bolt M, Stahly A, Lee JS, Bang TJ, Sachs PB, Deane KD, Humphries SM, Solomon JJ, Demoruelle MK. Transforming growth factor-beta is increased in sputum from individuals with rheumatoid arthritis-associated pulmonary fibrosis. Rheumatology (Oxford). 2025 Jun 01; 64(6):3989-3995.
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Calhoun KM, Armantrout E, Poch K, Caceres S, Lovell VK, Jones M, Malcolm KC, Vestal B, Wheeler E, Rysavy N, Manzer J, Aboellail I, Chatterjee D, Nick JA. Prospective Analysis of urINe LAM to Eliminate NTM Sputum Screening (PAINLESS) study: Rationale and trial design for testing urine lipoarabinomannan as a marker of NTM lung infection in cystic fibrosis. PLoS One. 2025; 20(3):e0309191.
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