 Neutrophil Activation
"Neutrophil Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonized particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil.
| Descriptor ID |
D018375
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| MeSH Number(s) |
G12.604
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| Concept/Terms |
Neutrophil Activation- Neutrophil Activation
- Activation, Neutrophil
- Activations, Neutrophil
- Neutrophil Activations
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Below are MeSH descriptors whose meaning is more general than "Neutrophil Activation".
Below are MeSH descriptors whose meaning is more specific than "Neutrophil Activation".
This graph shows the total number of publications written about "Neutrophil Activation" by people in this website by year, and whether "Neutrophil Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 2 | 3 | | 1997 | 1 | 0 | 1 | | 1998 | 5 | 1 | 6 | | 1999 | 0 | 1 | 1 | | 2000 | 2 | 2 | 4 | | 2001 | 3 | 0 | 3 | | 2002 | 0 | 1 | 1 | | 2003 | 2 | 3 | 5 | | 2004 | 1 | 1 | 2 | | 2005 | 2 | 4 | 6 | | 2006 | 7 | 0 | 7 | | 2007 | 1 | 3 | 4 | | 2008 | 1 | 1 | 2 | | 2009 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 0 | 2 | 2 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Neutrophil Activation" by people in Profiles.
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Michailidou D, Duvvuri B, Kuley R, Cuthbertson D, Grayson PC, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland LW, Pagnoux C, Seo P, Specks U, Sreih AG, Warrington KJ, Mustelin T, Monach PA, Merkel PA, Lood C. Neutrophil activation in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis and large-vessel vasculitis. Arthritis Res Ther. 2022 06 29; 24(1):160.
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Horn KJ, Schopper MA, Drigot ZG, Clark SE. Airway Prevotella promote TLR2-dependent neutrophil activation and rapid clearance of Streptococcus pneumoniae from the lung. Nat Commun. 2022 06 09; 13(1):3321.
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Duvvuri B, Baddour AA, Deane KD, Feser ML, Nelson JL, Demoruelle MK, Lood C. Mitochondrial N-formyl methionine peptides associate with disease activity as well as contribute to neutrophil activation in patients with rheumatoid arthritis. J Autoimmun. 2021 05; 119:102630.
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Cartwright IM, Curtis VF, Lanis JM, Alexeev EE, Welch N, Goldberg MS, Schaefer REM, Gao RY, Chun C, Fennimore B, Onyiah JC, Gerich ME, Dempsey PJ, Colgan SP. Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3. Mucosal Immunol. 2020 03; 13(2):230-244.
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Dakhama A, Al Mubarak R, Pavelka N, Voelker D, Seibold M, Ledford JG, Kraft M, Li L, Chu HW. Tollip Inhibits ST2 Signaling in Airway Epithelial Cells Exposed to Type 2 Cytokines and Rhinovirus. J Innate Immun. 2020; 12(1):103-115.
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Loi MM, Kelher M, Dzieciatkowska M, Hansen KC, Banerjee A, West FB, Stanley C, Briel M, Silliman CC. A comparison of different methods of red blood cell leukoreduction and additive solutions on the accumulation of neutrophil-priming activity during storage. Transfusion. 2018 08; 58(8):2003-2012.
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Vallelian F, Schaer CA, Deuel JW, Ingoglia G, Humar R, Buehler PW, Schaer DJ. Revisiting the putative role of heme as a trigger of inflammation. Pharmacol Res Perspect. 2018 04; 6(2):e00392.
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Poppelaars F, van Werkhoven MB, Kotimaa J, Veldhuis ZJ, Ausema A, Broeren SGM, Damman J, Hempel JC, Leuvenink HGD, Daha MR, van Son WJ, van Kooten C, van Os RP, Hillebrands JL, Seelen MA. Critical role for complement receptor C5aR2 in the pathogenesis of renal ischemia-reperfusion injury. FASEB J. 2017 07; 31(7):3193-3204.
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Kelher MR, Banerjee A, Gamboni F, Anderson C, Silliman CC. Antibodies to major histocompatibility complex class II antigens directly prime neutrophils and cause acute lung injury in a two-event in vivo rat model. Transfusion. 2016 12; 56(12):3004-3011.
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Hinz C, Aldrovandi M, Uhlson C, Marnett LJ, Longhurst HJ, Warner TD, Alam S, Slatter DA, Lauder SN, Allen-Redpath K, Collins PW, Murphy RC, Thomas CP, O'Donnell VB. Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid. J Biol Chem. 2016 Jun 24; 291(26):13448-64.
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