Antimicrobial Cationic Peptides
"Antimicrobial Cationic Peptides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Descriptor ID |
D023181
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MeSH Number(s) |
D12.644.050 D12.776.543.695.054
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Concept/Terms |
Antimicrobial Cationic Peptides- Antimicrobial Cationic Peptides
- Cationic Peptides, Antimicrobial
- Peptides, Antimicrobial Cationic
- Microbicidal Cationic Proteins
- Cationic Proteins, Microbicidal
- Proteins, Microbicidal Cationic
- Cationic Antimicrobial Peptides
- Antimicrobial Peptides, Cationic
- Peptides, Cationic Antimicrobial
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Below are MeSH descriptors whose meaning is more general than "Antimicrobial Cationic Peptides".
Below are MeSH descriptors whose meaning is more specific than "Antimicrobial Cationic Peptides".
This graph shows the total number of publications written about "Antimicrobial Cationic Peptides" by people in this website by year, and whether "Antimicrobial Cationic Peptides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 | 1998 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2002 | 1 | 1 | 2 | 2003 | 1 | 1 | 2 | 2004 | 1 | 0 | 1 | 2005 | 2 | 2 | 4 | 2006 | 6 | 0 | 6 | 2007 | 0 | 3 | 3 | 2008 | 1 | 1 | 2 | 2009 | 2 | 1 | 3 | 2010 | 1 | 2 | 3 | 2011 | 3 | 1 | 4 | 2012 | 0 | 1 | 1 | 2014 | 3 | 1 | 4 | 2015 | 1 | 2 | 3 | 2017 | 1 | 2 | 3 | 2018 | 3 | 0 | 3 | 2019 | 3 | 0 | 3 | 2020 | 1 | 2 | 3 | 2021 | 1 | 0 | 1 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antimicrobial Cationic Peptides" by people in Profiles.
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Zehr EP, Erzen CL, Oshima K, Langouet-Astrie CJ, LaRiviere WB, Shi D, Zhang F, McCollister BD, Windham SL, Rizzo AN, Bastarache JA, Horswill AR, Schmidt EP, Kwiecinski JM, Colbert JF. Bacterial pneumonia-induced shedding of epithelial heparan sulfate inhibits the bactericidal activity of cathelicidin in a murine model. Am J Physiol Lung Cell Mol Physiol. 2024 02 01; 326(2):L206-L212.
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Pezzanite LM, Chow L, Johnson V, Griffenhagen GM, Goodrich L, Dow S. Toll-like receptor activation of equine mesenchymal stromal cells to enhance antibacterial activity and immunomodulatory cytokine secretion. Vet Surg. 2021 May; 50(4):858-871.
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Cau L, Williams MR, Butcher AM, Nakatsuji T, Kavanaugh JS, Cheng JY, Shafiq F, Higbee K, Hata TR, Horswill AR, Gallo RL. Staphylococcus epidermidis protease EcpA can be a deleterious component of the skin microbiome in atopic dermatitis. J Allergy Clin Immunol. 2021 03; 147(3):955-966.e16.
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Honda JR, Hess T, Carlson R, Kandasamy P, Nieto Ramirez LM, Norton GJ, Virdi R, Islam MN, Mehaffy C, Hasan NA, Epperson LE, Hesser D, Alper S, Strong M, Flores SC, Voelker DR, Dobos KM, Chan ED. Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37. Am J Respir Cell Mol Biol. 2020 03; 62(3):354-363.
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Postolache TT, Akram F, Lee EE, Lowry CA, Stiller JW, Brenner LA, Streeten EA, Turecki G, Dwivedi Y. Increased brain vitamin D receptor expression and decreased expression of cathelicidin antimicrobial peptide in individuals who died by suicide. J Psychiatr Res. 2020 06; 125:75-84.
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Panja S, Bharti R, Dey G, Lynd NA, Chattopadhyay S. Coordination-Assisted Self-Assembled Polypeptide Nanogels to Selectively Combat Bacterial Infection. ACS Appl Mater Interfaces. 2019 Sep 18; 11(37):33599-33611.
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Theprungsirikul J, Skopelja-Gardner S, Meagher RE, Clancy JP, Zemanick ET, Ashare A, Rigby WFC. Dissociation of systemic and mucosal autoimmunity in cystic fibrosis. J Cyst Fibros. 2020 03; 19(2):196-202.
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Mant CT, Jiang Z, Gera L, Davis T, Nelson KL, Bevers S, Hodges RS. De Novo Designed Amphipathic a-Helical Antimicrobial Peptides Incorporating Dab and Dap Residues on the Polar Face To Treat the Gram-Negative Pathogen, Acinetobacter baumannii. J Med Chem. 2019 04 11; 62(7):3354-3366.
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Camargo Moreno M, Lewis JB, Kovacs EJ, Lowery EM. Lung allograft donors with excessive alcohol use have increased levels of human antimicrobial peptide LL-37. Alcohol. 2019 11; 80:109-117.
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Klyachkin YM, Idris A, Rodell CB, Tripathi H, Ye S, Nagareddy P, Asfour A, Gao E, Annabathula R, Ratajczak M, Burdick JA, Abdel-Latif A. Cathelicidin Related Antimicrobial Peptide (CRAMP) Enhances Bone Marrow Cell Retention and Attenuates Cardiac Dysfunction in a Mouse Model of Myocardial Infarction. Stem Cell Rev Rep. 2018 Oct; 14(5):702-714.
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