 Toll-Like Receptor 4
"Toll-Like Receptor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.
| Descriptor ID |
D051197
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| MeSH Number(s) |
D12.776.543.750.705.910.500.400
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| Concept/Terms |
Toll-Like Receptor 4- Toll-Like Receptor 4
- Toll Like Receptor 4
- Toll-4 Receptor
- Toll 4 Receptor
- TLR4 Receptor
- Receptor, TLR4
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Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 4".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 4".
This graph shows the total number of publications written about "Toll-Like Receptor 4" by people in this website by year, and whether "Toll-Like Receptor 4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 6 | 6 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 10 | 11 | | 2005 | 3 | 5 | 8 | | 2006 | 3 | 1 | 4 | | 2007 | 4 | 5 | 9 | | 2008 | 7 | 3 | 10 | | 2009 | 12 | 4 | 16 | | 2010 | 7 | 4 | 11 | | 2011 | 6 | 3 | 9 | | 2012 | 7 | 7 | 14 | | 2013 | 7 | 9 | 16 | | 2014 | 15 | 5 | 20 | | 2015 | 11 | 5 | 16 | | 2016 | 6 | 3 | 9 | | 2017 | 3 | 6 | 9 | | 2018 | 4 | 0 | 4 | | 2019 | 3 | 3 | 6 | | 2020 | 5 | 6 | 11 | | 2021 | 2 | 2 | 4 | | 2023 | 2 | 1 | 3 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Toll-Like Receptor 4" by people in Profiles.
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Timkovich AE, Holling GA, Afzali MF, Kisiday J, Santangelo KS. TLR4 antagonism provides short-term but not long-term clinical benefit in a full-depth cartilage defect mouse model. Connect Tissue Res. 2024 01; 65(1):26-40.
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Brown KT, Levis SC, O'Neill CE, Levy C, Rice KC, Watkins LR, Bachtell RK. Toll-like receptor 4 antagonists reduce cocaine-primed reinstatement of drug seeking. Psychopharmacology (Berl). 2023 Jul; 240(7):1587-1600.
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Ermisch AF, Bidne KL, Kurz SG, Bochantin KA, Wood JR. Ovarian inflammation mediated by Toll-like receptor 4 increased transcripts of maternal effect genes and decreased embryo development?. Biol Reprod. 2023 03 13; 108(3):423-436.
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Glaser K, Kern D, Speer CP, Schlegel N, Schwab M, Thome UH, H?rtel C, Wright CJ. Imbalanced Inflammatory Responses in Preterm and Term Cord Blood Monocytes and Expansion of the CD14+CD16+ Subset upon Toll-like Receptor Stimulation. Int J Mol Sci. 2023 Mar 03; 24(5).
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Langgartner D, Amoroso M, Kempter E, Kustermann M, Scheurer J, Lowry CA, Strau? G, Reber SO. Mycobacterium vaccae protects against glucocorticoid resistance resulting from combined physical and psychosocial trauma in mice. Brain Behav Immun. 2023 03; 109:221-234.
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Muscat SM, Deems NP, Butler MJ, Scaria EA, Bettes MN, Cleary SP, Bockbrader RH, Maier SF, Barrientos RM. Selective TLR4 Antagonism Prevents and Reverses Morphine-Induced Persistent Postoperative Cognitive Dysfunction, Dysregulation of Synaptic Elements, and Impaired BDNF Signaling in Aged Male Rats. J Neurosci. 2023 01 04; 43(1):155-172.
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Perkins RK, van Vliet S, Miranda ER, Fuller KNZ, Beisswenger PJ, Wilund KR, Paluska SA, Burd NA, Haus JM. Advanced Glycation End Products and Inflammatory Cytokine Profiles in Maintenance Hemodialysis Patients After the Ingestion of a Protein-Dense Meal. J Ren Nutr. 2023 Jan; 33(1):181-192.
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Gergen AK, Jarrett MJ, Li A, Meng X, Pratap A, Fullerton DA, Weyant MJ. Toll-like Receptor 4 Mediates Reflux-Induced Inflammation in a Murine Reflux Model. Semin Thorac Cardiovasc Surg. 2022; 34(4):1324-1335.
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Jain S, Plenter R, Nydam T, Gill RG, Jani A. Deletion of TLR4 reduces apoptosis and improves histology in a murine kidney transplant model. Sci Rep. 2021 08 10; 11(1):16182.
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Abdelazeem KNM, Kalo MZ, Beer-Hammer S, Lang F. The gut microbiota metabolite urolithin A inhibits NF-?B activation in LPS stimulated BMDMs. Sci Rep. 2021 03 29; 11(1):7117.
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