 Thiazolidinediones
"Thiazolidinediones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
THIAZOLES with two keto oxygens. Members are insulin-sensitizing agents which overcome INSULIN RESISTANCE by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
| Descriptor ID |
D045162
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| MeSH Number(s) |
D02.886.675.933 D03.383.129.708.933
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thiazolidinediones".
Below are MeSH descriptors whose meaning is more specific than "Thiazolidinediones".
This graph shows the total number of publications written about "Thiazolidinediones" by people in this website by year, and whether "Thiazolidinediones" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 2 | 0 | 2 | | 2003 | 5 | 0 | 5 | | 2004 | 2 | 2 | 4 | | 2005 | 5 | 1 | 6 | | 2006 | 8 | 3 | 11 | | 2007 | 6 | 2 | 8 | | 2008 | 6 | 2 | 8 | | 2009 | 4 | 4 | 8 | | 2010 | 6 | 2 | 8 | | 2011 | 2 | 1 | 3 | | 2012 | 4 | 2 | 6 | | 2013 | 5 | 1 | 6 | | 2014 | 3 | 1 | 4 | | 2015 | 4 | 2 | 6 | | 2016 | 4 | 1 | 5 | | 2017 | 3 | 3 | 6 | | 2018 | 1 | 1 | 2 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thiazolidinediones" by people in Profiles.
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Abushamat LA, Reusch JEB. Evolving Concepts of Type 2 Diabetes Management. Med Clin North Am. 2021 Nov; 105(6):955-966.
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Feng L, Lu S, Zheng Z, Chen Y, Zhao Y, Song K, Xue H, Jin L, Li Y, Huang C, Li YM, Zhang J. Identification of an allosteric hotspot for additive activation of PPAR? in antidiabetic effects. Sci Bull (Beijing). 2021 08 15; 66(15):1559-1570.
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Lane SL, Doyle AS, Bales ES, Houck JA, Lorca RA, Moore LG, Julian CG. Peroxisome proliferator-activated receptor gamma blunts endothelin-1-mediated contraction of the uterine artery in a murine model of high-altitude pregnancy. FASEB J. 2020 03; 34(3):4283-4292.
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Giordano TJ, Haugen BR, Sherman SI, Shah MH, Caoili EM, Koenig RJ. Pioglitazone Therapy of PAX8-PPAR? Fusion Protein Thyroid Carcinoma. J Clin Endocrinol Metab. 2018 04 01; 103(4):1277-1281.
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Gidding SS, Bacha F, Bjornstad P, Levitt Katz LE, Levitsky LL, Lynch J, Tryggestad JB, Weinstock RS, El Ghormli L, Lima JAC. Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study. J Pediatr. 2018 01; 192:86-92.e5.
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Gower EW, Lovato JF, Ambrosius WT, Chew EY, Danis RP, Davis MD, Goff DC, Greven CM. Lack of Longitudinal Association Between Thiazolidinediones and Incidence and Progression of Diabetic Eye Disease: The ACCORD Eye Study. Am J Ophthalmol. 2018 03; 187:138-147.
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Lyons DN, Zhang L, Danaher RJ, Miller CS, Westlund KN. PPAR? Agonists Attenuate Trigeminal Neuropathic Pain. Clin J Pain. 2017 12; 33(12):1071-1080.
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Fixen CW, Fixen DR. Managing and maintaining bone mineral density in diabetes patients with pharmacotherapy. Expert Opin Pharmacother. 2017 Dec; 18(18):2001-2006.
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Home PD, Ahr?n B, Reusch JEB, Rendell M, Weissman PN, Cirkel DT, Miller D, Ambery P, Carr MC, Nauck MA. Three-year data from 5 HARMONY phase 3 clinical trials of albiglutide in type 2 diabetes mellitus: Long-term efficacy with or without rescue therapy. Diabetes Res Clin Pract. 2017 Sep; 131:49-60.
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Bortz DM, Wu HQ, Schwarcz R, Bruno JP. Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex. Neuropharmacology. 2017 Jul 15; 121:69-78.
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