 Interleukin-8
"Interleukin-8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.
| Descriptor ID |
D016209
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| MeSH Number(s) |
D12.644.276.374.200.120.800 D12.644.276.374.465.312 D12.776.467.374.200.120.800 D12.776.467.374.465.246 D23.125.300.120.800 D23.469.200.120.800 D23.529.374.200.120.800 D23.529.374.465.312
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| Concept/Terms |
Interleukin-8- Interleukin-8
- Interleukin 8
- IL8
- Monocyte-Derived Neutrophil Chemotactic Factor
- Neutrophil Activation Factor
- Neutrophil-Activating Peptide, Lymphocyte-Derived
- Lymphocyte-Derived Neutrophil-Activating Peptide
- Neutrophil Activating Peptide, Lymphocyte Derived
- Neutrophil-Activating Peptide, Monocyte-Derived
- Monocyte-Derived Neutrophil-Activating Peptide
- Neutrophil Activating Peptide, Monocyte Derived
- Alveolar Macrophage Chemotactic Factor-I
- Alveolar Macrophage Chemotactic Factor I
- AMCF-I
- Anionic Neutrophil-Activating Peptide
- Anionic Neutrophil Activating Peptide
- Neutrophil-Activating Peptide, Anionic
- Peptide, Anionic Neutrophil-Activating
- Chemokine CXCL8
- CXCL8, Chemokine
- Chemokines, CXCL8
- CXCL8 Chemokines
- Chemotactic Factor, Macrophage-Derived
- Chemotactic Factor, Macrophage Derived
- Macrophage-Derived Chemotactic Factor
- Chemotactic Factor, Neutrophil
- Neutrophil Chemotactic Factor
- Chemotactic Factor, Neutrophil, Monocyte-Derived
- CXCL8 Chemokine
- Chemokine, CXCL8
- Granulocyte Chemotactic Peptide-Interleukin-8
- Chemotactic Peptide-Interleukin-8, Granulocyte
- Granulocyte Chemotactic Peptide Interleukin 8
- IL-8
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Below are MeSH descriptors whose meaning is more general than "Interleukin-8".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-8".
This graph shows the total number of publications written about "Interleukin-8" by people in this website by year, and whether "Interleukin-8" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 4 | 0 | 4 | | 1996 | 2 | 3 | 5 | | 1997 | 2 | 4 | 6 | | 1998 | 1 | 6 | 7 | | 1999 | 0 | 2 | 2 | | 2000 | 5 | 1 | 6 | | 2001 | 1 | 6 | 7 | | 2002 | 2 | 6 | 8 | | 2003 | 2 | 3 | 5 | | 2004 | 1 | 3 | 4 | | 2005 | 2 | 4 | 6 | | 2006 | 3 | 2 | 5 | | 2007 | 2 | 5 | 7 | | 2008 | 2 | 6 | 8 | | 2009 | 3 | 5 | 8 | | 2010 | 2 | 2 | 4 | | 2011 | 1 | 7 | 8 | | 2012 | 1 | 7 | 8 | | 2013 | 1 | 3 | 4 | | 2014 | 4 | 1 | 5 | | 2015 | 0 | 5 | 5 | | 2016 | 0 | 2 | 2 | | 2017 | 2 | 3 | 5 | | 2018 | 1 | 5 | 6 | | 2019 | 0 | 3 | 3 | | 2020 | 0 | 4 | 4 | | 2021 | 0 | 4 | 4 | | 2022 | 2 | 4 | 6 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 1 | 2 | | 2025 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-8" by people in Profiles.
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Levy MV, Fandl HK, Hijmans JG, Stockelman KA, Ruzzene ST, Reiakvam WR, Goldthwaite ZA, Greiner JJ, DeSouza CA, Garcia VP. Effect of 17?-Estradiol on Endothelial Cell Expression of Inflammation- Related MicroRNA. Microrna. 2025; 14(1):3-8.
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Garcia VP, Stockelman KA, Levy MV, Fandl HK, Goulding A, Hijmans JG, Ruzzene ST, Berry AR, Greiner JJ, DeSouza CA. Microvesicles Derived from Nitric Oxide Synthase-Inhibited Endothelial Cells Promote Cell Dysfunction. J Vasc Res. 2025; 62(1):10-21.
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Lake JA, Woods E, Hoffmeyer E, Schaller KL, Cruz-Cruz J, Fernandez J, Tufa D, Kooiman B, Hall SC, Jones D, Hayashi M, Verneris MR. Directing B7-H3 chimeric antigen receptor T cell homing through IL-8 induces potent antitumor activity against pediatric sarcoma. J Immunother Cancer. 2024 Jul 23; 12(7).
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Foley KE, Winder Z, Sudduth TL, Martin BJ, Nelson PT, Jicha GA, Harp JP, Weekman EM, Wilcock DM. Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort. Alzheimers Dement. 2024 02; 20(2):1374-1386.
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Erlandson G, Magzamen S, Sharp JL, Mitra S, Jones K, Poole JA, Bradford M, Nonnenmann M, Reynolds SJ, Schaeffer JW. Preliminary investigation of a hypertonic saline nasal rinse as a hygienic intervention in dairy workers. J Occup Environ Hyg. 2023 01; 20(1):14-22.
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Leung DH, Devaraj S, Goodrich NP, Chen X, Rajapakshe D, Ye W, Andreev V, Minard CG, Guffey D, Molleston JP, Bass LM, Karpen SJ, Kamath BM, Wang KS, Sundaram SS, Rosenthal P, McKiernan P, Loomes KM, Jensen MK, Horslen SP, Bezerra JA, Magee JC, Merion RM, Sokol RJ, Shneider BL, Alonso E, Bass L, Kelly S, Riordan M, Melin-Aldana H, Bezerra J, Bove K, Heubi J, Miethke A, Tiao G, Denlinger J, Chapman E, Sokol R, Feldman A, Mack C, Narkewicz M, Suchy F, Sundaram SS, Van Hove J, Garcia B, Kauma M, Kocher K, Steinbeiss M, Lovell M, Loomes KM, Piccoli D, Rand E, Russo P, Spinner N, Erlichman J, Stalford S, Pakstis D, King S, Squires R, Sindhi R, Venkat V, Bukauskas K, McKiernan P, Haberstroh L, Squires J, Rosenthal P, Bull L, Curry J, Langlois C, Kim G, Teckman J, Kociela V, Nagy R, Patel S, Cerkoski J, Molleston JP, Bozic M, Subbarao G, Klipsch A, Sawyers C, Cummings O, Horslen SP, Murray K, Hsu E, Cooper K, Young M, Finn L, Kamath BM, Ng V, Quammie C, Putra J, Sharma D, Parmar A, Guthery S, Jensen K, Rutherford A, Lowichik A, Book L, Meyers R, Hall T, Wang KS, Michail S, Thomas D, Goodhue C, Kohli R, Wang L, Soufi N, Thomas D, Karpen S, Gupta N, Romero R, Vos MB, Tory R, Berauer JP, Abramowsky C, McFall J, Shneider BL, Harpavat S, Hertel P, Leung D, Tessier M, Schady D, Cavallo L, Olvera D, Banks C, Tsai C, Thompson R, Doo E, Hoofnagle J, Sherker A, Torrance R, Hall S, Magee J, Merion R, Spino C, Ye W. Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease. Hepatology. 2023 02 01; 77(2):530-545.
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Kahn D, Macias E, Zarini S, Garfield A, Zemski Berry K, MacLean P, Gerszten RE, Libby A, Solt C, Schoen J, Bergman BC. Exploring Visceral and Subcutaneous Adipose Tissue Secretomes in Human Obesity: Implications for Metabolic Disease. Endocrinology. 2022 10 11; 163(11).
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Bai X, Bai A, Tomasicchio M, Hagman JR, Buckle AM, Gupta A, Kadiyala V, Bevers S, Serban KA, Kim K, Feng Z, Spendier K, Hagen G, Fornis L, Griffith DE, Dzieciatkowska M, Sandhaus RA, Gerber AN, Chan ED. a1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages. J Immunol. 2022 11 01; 209(9):1746-1759.
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Rotar EP, Haywood NS, Mehaffey JH, Money DT, Ta HQ, Stoler MH, Teman NR, Laubach VE, Kron IL, Roeser ME. Gastric Aspiration and Ventilator-Induced Model of Acute Respiratory Distress Syndrome in Swine. J Surg Res. 2022 12; 280:280-287.
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Berg C, Wedemeyer MJ, Melynis M, Schlimgen RR, Hansen LH, V?ben? J, Peterson FC, Volkman BF, Rosenkilde MM, L?ttichau HR. The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal ?-hairpin and induces neutrophil migration as a selective CXCR2 agonist. PLoS Pathog. 2022 03; 18(3):e1010355.
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