 Quorum Sensing
"Quorum Sensing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phenomenon where microorganisms communicate and coordinate their behavior by the accumulation of signaling molecules. A reaction occurs when a substance accumulates to a sufficient concentration. This is most commonly seen in bacteria.
| Descriptor ID |
D053038
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| MeSH Number(s) |
G04.085.700 G06.550.700
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| Concept/Terms |
Quorum Quenching- Quorum Quenching
- Quenching, Quorum
- Quenchings, Quorum
- Quorum Quenchings
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Below are MeSH descriptors whose meaning is more general than "Quorum Sensing".
Below are MeSH descriptors whose meaning is more specific than "Quorum Sensing".
This graph shows the total number of publications written about "Quorum Sensing" by people in this website by year, and whether "Quorum Sensing" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 2 | 0 | 2 | | 2007 | 4 | 0 | 4 | | 2008 | 1 | 1 | 2 | | 2009 | 2 | 1 | 3 | | 2010 | 3 | 1 | 4 | | 2011 | 3 | 1 | 4 | | 2012 | 2 | 0 | 2 | | 2013 | 4 | 0 | 4 | | 2014 | 3 | 1 | 4 | | 2015 | 2 | 0 | 2 | | 2016 | 3 | 1 | 4 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 2 | 3 | | 2019 | 3 | 1 | 4 | | 2020 | 1 | 3 | 4 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 | | 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "Quorum Sensing" by people in Profiles.
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John MS, Chinnappan M, Sturges CI, Artami M, Bhattacharya M, Keogh RA, Kavanaugh JS, Jain S, Gedamu H, Komarovsky J, Velasquez M, Sharma T, McDonald JG, Horswill AR, Harris-Tryon TA. Skin androgens regulate Staphylococcus aureus pathogenicity via quorum sensing. Nat Microbiol. 2026 Mar; 11(3):704-717.
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Anderson CM, Wilkening RV, Boulos S, Keys TG, Ebert M-O, Zinsli LV, Krusche J, Loessner MJ, Feldstein SF, Chang JC, Peschel A, Horswill AR, Shen Y, Federle MJ. A teichoic acid-like wall modification associated with immune suppression is socially regulated in Streptococcus pyogenes. mBio. 2026 Apr 08; 17(4):e0380125.
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Bagood MD, Marjanovic J, Jiang N, Chan H, Dokoshi T, Cavagnero KJ, Li F, Roso-Mares A, Almoughrabie S, Liu E, Pastar I, Tomic-Canic M, Horswill AR, Gallo RL. Staphylococcus aureus accessory gene regulator quorum-sensing system inhibits keratinocyte lipid enzymes and delays wound repair. J Clin Invest. 2025 Oct 15; 135(20).
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Eisenbraun EL, Vulpis TD, Prosser BN, Horswill AR, Blackwell HE. Synthetic Peptides Capable of Potent Multigroup Staphylococcal Quorum Sensing Activation and Inhibition in Both Cultures and Biofilm Communities. J Am Chem Soc. 2024 Jun 12; 146(23):15941-15954.
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Wilkening RV, Langouët-Astrié C, Severn MM, Federle MJ, Horswill AR. Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model. Cell Rep. 2023 11 28; 42(11):113332.
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Chang JC, Wilkening RV, Rahbari KM, Federle MJ. Quorum Sensing Regulation of a Major Facilitator Superfamily Transporter Affects Multiple Streptococcal Virulence Factors. J Bacteriol. 2022 Sep 20; 204(9):e0017622.
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Severn MM, Cho YK, Manzer HS, Bunch ZL, Shahbandi A, Todd DA, Cech NB, Horswill AR. The Commensal Staphylococcus warneri Makes Peptide Inhibitors of MRSA Quorum Sensing that Protect Skin from Atopic or Necrotic Damage. J Invest Dermatol. 2022 12; 142(12):3349-3352.e5.
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West KHJ, Shen W, Eisenbraun EL, Yang T, Vasquez JK, Horswill AR, Blackwell HE. Non-Native Peptides Capable of Pan-Activating the agr Quorum Sensing System across Multiple Specificity Groups of Staphylococcus epidermidis. ACS Chem Biol. 2021 06 18; 16(6):1070-1078.
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Fritts RK, McCully AL, McKinlay JB. Extracellular Metabolism Sets the Table for Microbial Cross-Feeding. Microbiol Mol Biol Rev. 2021 02 17; 85(1).
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El-Khouly OA, Henen MA, El-Sayed MA, Shabaan MI, El-Messery SM. Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study. Bioorg Med Chem. 2021 02 01; 31:115976.
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