 Quorum Sensing
"Quorum Sensing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phenomenon where microorganisms communicate and coordinate their behavior by the accumulation of signaling molecules. A reaction occurs when a substance accumulates to a sufficient concentration. This is most commonly seen in bacteria.
| Descriptor ID |
D053038
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| MeSH Number(s) |
G04.085.700 G06.550.700
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| Concept/Terms |
Quorum Quenching- Quorum Quenching
- Quenching, Quorum
- Quenchings, Quorum
- Quorum Quenchings
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Below are MeSH descriptors whose meaning is more general than "Quorum Sensing".
Below are MeSH descriptors whose meaning is more specific than "Quorum Sensing".
This graph shows the total number of publications written about "Quorum Sensing" by people in this website by year, and whether "Quorum Sensing" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 2 | 0 | 2 | | 2007 | 4 | 0 | 4 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 1 | 3 | | 2010 | 3 | 1 | 4 | | 2011 | 3 | 1 | 4 | | 2012 | 2 | 0 | 2 | | 2013 | 4 | 0 | 4 | | 2014 | 3 | 1 | 4 | | 2015 | 2 | 0 | 2 | | 2016 | 3 | 1 | 4 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 2 | 3 | | 2019 | 3 | 1 | 4 | | 2020 | 1 | 3 | 4 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Quorum Sensing" by people in Profiles.
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Wilkening RV, Langou?t-Astri? C, Severn MM, Federle MJ, Horswill AR. Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model. Cell Rep. 2023 11 28; 42(11):113332.
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Severn MM, Cho YK, Manzer HS, Bunch ZL, Shahbandi A, Todd DA, Cech NB, Horswill AR. The Commensal Staphylococcus warneri Makes Peptide Inhibitors of MRSA Quorum Sensing that Protect Skin from Atopic or Necrotic Damage. J Invest Dermatol. 2022 12; 142(12):3349-3352.e5.
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West KHJ, Shen W, Eisenbraun EL, Yang T, Vasquez JK, Horswill AR, Blackwell HE. Non-Native Peptides Capable of Pan-Activating the agr Quorum Sensing System across Multiple Specificity Groups of Staphylococcus epidermidis. ACS Chem Biol. 2021 06 18; 16(6):1070-1078.
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El-Khouly OA, Henen MA, El-Sayed MA, Shabaan MI, El-Messery SM. Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study. Bioorg Med Chem. 2021 02 01; 31:115976.
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Schilcher K, Horswill AR. Staphylococcal Biofilm Development: Structure, Regulation, and Treatment Strategies. Microbiol Mol Biol Rev. 2020 08 19; 84(3).
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Jones DD, Caesar LK, Pelzer CV, Crandall WJ, Jenul C, Todd DA, Horswill AR, Cech NB. Targeted and untargeted analysis of secondary metabolites to monitor growth and quorum sensing inhibition for methicillin-resistant Staphylococcus aureus (MRSA). J Microbiol Methods. 2020 09; 176:106000.
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Brown MM, Kwiecinski JM, Cruz LM, Shahbandi A, Todd DA, Cech NB, Horswill AR. Novel Peptide from Commensal Staphylococcus simulans Blocks Methicillin-Resistant Staphylococcus aureus Quorum Sensing and Protects Host Skin from Damage. Antimicrob Agents Chemother. 2020 05 21; 64(6).
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Horswill AR, Gordon CP. Structure-Activity Relationship Studies of Small Molecule Modulators of the Staphylococcal Accessory Gene Regulator. J Med Chem. 2020 03 26; 63(6):2705-2730.
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Grundstad ML, Parlet CP, Kwiecinski JM, Kavanaugh JS, Crosby HA, Cho YS, Heilmann K, Diekema DJ, Horswill AR. Quorum Sensing, Virulence, and Antibiotic Resistance of USA100 Methicillin-Resistant Staphylococcus aureus Isolates. mSphere. 2019 08 14; 4(4).
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Williams MR, Costa SK, Zaramela LS, Khalil S, Todd DA, Winter HL, Sanford JA, O'Neill AM, Liggins MC, Nakatsuji T, Cech NB, Cheung AL, Zengler K, Horswill AR, Gallo RL. Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis. Sci Transl Med. 2019 05 01; 11(490).
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