 PPAR gamma
"PPAR gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR ALPHA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES. It is a target of THIAZOLIDINEDIONES for control of DIABETES MELLITUS.
| Descriptor ID |
D047495
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| MeSH Number(s) |
D12.776.826.239.588
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| Concept/Terms |
PPAR gamma- PPAR gamma
- PPARgamma
- Thiazolidinedione Receptor
- Receptor, Thiazolidinedione
- Peroxisome Proliferator-Activated Receptor gamma
- Peroxisome Proliferator Activated Receptor gamma
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Below are MeSH descriptors whose meaning is more general than "PPAR gamma".
Below are MeSH descriptors whose meaning is more specific than "PPAR gamma".
This graph shows the total number of publications written about "PPAR gamma" by people in this website by year, and whether "PPAR gamma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 3 | 0 | 3 | | 2005 | 3 | 2 | 5 | | 2006 | 5 | 3 | 8 | | 2007 | 5 | 2 | 7 | | 2008 | 3 | 2 | 5 | | 2009 | 1 | 2 | 3 | | 2010 | 5 | 1 | 6 | | 2011 | 1 | 2 | 3 | | 2012 | 3 | 4 | 7 | | 2013 | 4 | 7 | 11 | | 2014 | 1 | 5 | 6 | | 2015 | 2 | 5 | 7 | | 2016 | 0 | 2 | 2 | | 2017 | 2 | 3 | 5 | | 2018 | 3 | 3 | 6 | | 2019 | 3 | 1 | 4 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 4 | 5 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "PPAR gamma" by people in Profiles.
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Wang P, Xu J, Sun Q, Ge Q, Qiu M, Zou K, Ying J, Yuan W, Chen J, Zeng Q, Cui Q, Jin H, Zhang C, Li F. Chondroprotective Mechanism of Eucommia ulmoides Oliv.-Glycyrrhiza uralensis Fisch. Couplet Medicines in Knee Osteoarthritis via Experimental Study and Network Pharmacology Analysis. Drug Des Devel Ther. 2023; 17:633-646.
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Grobbee EJ, de Jong VD, Schrieks IC, Tushuizen ME, Holleboom AG, Tardif JC, Lincoff AM, Schwartz GG, Castro Cabezas M, Grobbee DE. Improvement of non-invasive tests of liver steatosis and fibrosis as indicators for non-alcoholic fatty liver disease in type 2 diabetes mellitus patients with elevated cardiovascular risk profile using the PPAR-a/? agonist aleglitazar. PLoS One. 2022; 17(11):e0277706.
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Luo W, Kim Y, Jensen ME, Herlea-Pana O, Wang W, Rudolph MC, Friedman JE, Chernausek SD, Jiang S. miR-130b/301b Is a Negative Regulator of Beige Adipogenesis and Energy Metabolism In Vitro and In Vivo. Diabetes. 2022 11 01; 71(11):2360-2371.
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Dwyer-Nield LD, McArthur DG, Hudish TM, Hudish LI, Mirita C, Sompel K, Smith AJ, Alavi K, Ghosh M, Merrick DT, Tennis MA, Keith RL. PPARgamma agonism inhibits progression of premalignant lesions in a murine lung squamous cell carcinoma model. Int J Cancer. 2022 Dec 15; 151(12):2195-2205.
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Vaughan OR, Rosario FJ, Chan J, Cox LA, Ferchaud-Roucher V, Zemski-Berry KA, Reusch JEB, Keller AC, Powell TL, Jansson T. Maternal obesity causes fetal cardiac hypertrophy and alters adult offspring myocardial metabolism in mice. J Physiol. 2022 07; 600(13):3169-3191.
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El Kharbili M, Aviszus K, Sasse SK, Zhao X, Serban KA, Majka SM, Gerber AN, Gally F. Macrophage programming is regulated by a cooperative interaction between fatty acid binding protein 5 and peroxisome proliferator-activated receptor ?. FASEB J. 2022 05; 36(5):e22300.
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Smith AJ, Do P, Sompel K, Elango A, Tennis MA. miR-520a-5p regulates Frizzled 9 expression and mediates effects of cigarette smoke and iloprost chemoprevention. Sci Rep. 2022 02 11; 12(1):2388.
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Glodowski M, Christen S, Saxon DR, Hegele RA, Eckel RH. Novel PPARG mutation in multiple family members with chylomicronemia. J Clin Lipidol. 2021 May-Jun; 15(3):431-434.
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Feng L, Lu S, Zheng Z, Chen Y, Zhao Y, Song K, Xue H, Jin L, Li Y, Huang C, Li YM, Zhang J. Identification of an allosteric hotspot for additive activation of PPAR? in antidiabetic effects. Sci Bull (Beijing). 2021 08 15; 66(15):1559-1570.
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Lane SL, Doyle AS, Bales ES, Houck JA, Lorca RA, Moore LG, Julian CG. Peroxisome proliferator-activated receptor gamma blunts endothelin-1-mediated contraction of the uterine artery in a murine model of high-altitude pregnancy. FASEB J. 2020 03; 34(3):4283-4292.
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