 Acute Lung Injury
"Acute Lung Injury" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Descriptor ID |
D055371
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| MeSH Number(s) |
C08.381.520.500
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| Concept/Terms |
Acute Lung Injury- Acute Lung Injury
- Acute Lung Injuries
- Lung Injuries, Acute
- Lung Injury, Acute
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Below are MeSH descriptors whose meaning is more general than "Acute Lung Injury".
Below are MeSH descriptors whose meaning is more specific than "Acute Lung Injury".
This graph shows the total number of publications written about "Acute Lung Injury" by people in this website by year, and whether "Acute Lung Injury" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 3 | 0 | 3 | | 2009 | 9 | 1 | 10 | | 2010 | 9 | 2 | 11 | | 2011 | 16 | 4 | 20 | | 2012 | 17 | 4 | 21 | | 2013 | 14 | 4 | 18 | | 2014 | 8 | 2 | 10 | | 2015 | 6 | 2 | 8 | | 2016 | 2 | 2 | 4 | | 2017 | 7 | 0 | 7 | | 2018 | 3 | 0 | 3 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 3 | 4 | | 2021 | 6 | 0 | 6 | | 2022 | 8 | 0 | 8 | | 2023 | 6 | 0 | 6 | | 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Acute Lung Injury" by people in Profiles.
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Wallbank A, Sosa A, Colson A, Farooqi H, Kaye E, Warner K, Albers DJ, Sottile PD, Smith BJ. Dynamic driving pressure predicts ventilator-induced lung injury in mice with and without endotoxin-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2025 Jan 01; 328(1):L159-L175.
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Tunstead C, Volkova E, Dunbar H, Hawthorne IJ, Bell A, Crowe L, Masterson JC, Dos Santos CC, McNicholas B, Laffey JG, English K. The ARDS microenvironment enhances MSC-induced repair via VEGF in experimental acute lung inflammation. Mol Ther. 2024 Oct 02; 32(10):3422-3432.
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Pokharel MD, Fu P, Garcia-Flores A, Yegambaram M, Lu Q, Sun X, Unwalla H, Aggarwal S, Fineman JR, Wang T, Black SM. Inflammatory lung injury is associated with endothelial cell mitochondrial fission and requires the nitration of RhoA and cytoskeletal remodeling. Free Radic Biol Med. 2024 Aug 20; 221:125-135.
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Heneghan JA, Walker SB, Fawcett A, Bennett TD, Dziorny AC, Sanchez-Pinto LN, Farris RWD, Winter MC, Badke C, Martin B, Brown SR, McCrory MC, Ness-Cochinwala M, Rogerson C, Baloglu O, Harwayne-Gidansky I, Hudkins MR, Kamaleswaran R, Gangadharan S, Tripathi S, Mendonca EA, Markovitz BP, Mayampurath A, Spaeder MC. The Pediatric Data Science and Analytics Subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators Network: Use of Supervised Machine Learning Applications in Pediatric Critical Care Medicine Research. Pediatr Crit Care Med. 2024 Apr 01; 25(4):364-374.
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Roy RM, Allawzi A, Burns N, Sul C, Rubio V, Graham J, Stenmark K, Nozik ES, Tuder RM, Vohwinkel CU. Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury. FASEB J. 2023 12; 37(12):e23316.
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Tea K, Zu Y, Chung CH, Pagliaro J, Espinoza-Barrera D, Mehta P, Grewal H, Douglas IS, Khan YA, Shaffer JG, Denson JL. The Relationship Between Metabolic Syndrome and Mortality Among Patients With Acute Respiratory Distress Syndrome in Acute Respiratory Distress Syndrome Network and Prevention and Early Treatment of Acute Lung Injury Network Trials. Crit Care Med. 2024 03 01; 52(3):407-419.
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Elajaili HB, Dee NM, Dikalov SI, Kao JPY, Nozik ES. Use of Electron Paramagnetic Resonance (EPR) to Evaluate Redox Status in a Preclinical Model of Acute Lung Injury. Mol Imaging Biol. 2024 Jun; 26(3):495-502.
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Wallbank AM, Vaughn AE, Niemiec S, Bilodeaux J, Lehmann T, Knudsen L, Kolanthai E, Seal S, Zgheib C, Nozik E, Liechty KW, Smith BJ. CNP-miR146a improves outcomes in a two-hit acute- and ventilator-induced lung injury model. Nanomedicine. 2023 06; 50:102679.
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Sul C, Lewis C, Dee N, Burns N, Oshima K, Schmidt E, Vohwinkel C, Nozik E. Release of extracellular superoxide dismutase into alveolar fluid protects against acute lung injury and inflammation in Staphylococcus aureus pneumonia. Am J Physiol Lung Cell Mol Physiol. 2023 04 01; 324(4):L445-L455.
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Vohwinkel CU, Burns N, Coit E, Yuan X, Vladar EK, Sul C, Schmidt EP, Carmeliet P, Stenmark K, Nozik ES, Tuder RM, Eltzschig HK. HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury. JCI Insight. 2022 12 22; 7(24).
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