Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christina Coughlan

Concepts (363)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Alzheimer Disease
11
2026
614
2.330
Why?
Extracellular Vesicles
9
2025
160
2.080
Why?
Exosomes
3
2023
104
0.810
Why?
Astrocytes
4
2022
218
0.790
Why?
White Matter
2
2023
150
0.750
Why?
Gliosis
2
2023
29
0.730
Why?
Proteasome Endopeptidase Complex
2
2022
162
0.720
Why?
Glial Fibrillary Acidic Protein
2
2025
111
0.710
Why?
Sialyltransferases
8
1999
13
0.700
Why?
Amyloid beta-Protein Precursor
5
2022
64
0.670
Why?
Healthy Aging
1
2021
37
0.650
Why?
Ultracentrifugation
1
2020
50
0.650
Why?
Memory, Episodic
1
2021
54
0.650
Why?
Neurons
8
2026
1632
0.570
Why?
Amyloid beta-Peptides
6
2026
236
0.550
Why?
Saccharomyces cerevisiae
5
2022
568
0.540
Why?
Proteomics
4
2026
1192
0.500
Why?
Peptide Fragments
3
2022
706
0.460
Why?
Nanoparticles
1
2020
514
0.420
Why?
Cognitive Dysfunction
3
2025
451
0.420
Why?
Dexamethasone
7
1999
373
0.390
Why?
Brain Ischemia
2
2025
355
0.320
Why?
Herpes Zoster
3
2024
315
0.320
Why?
Islet Amyloid Polypeptide
2
2021
48
0.320
Why?
Down Syndrome
4
2022
523
0.310
Why?
Sialoglycoproteins
3
1997
158
0.280
Why?
Protein Folding
3
2005
283
0.270
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
2
2025
152
0.260
Why?
Aging
4
2026
1968
0.250
Why?
Interleukin-6
3
2026
791
0.250
Why?
Biomarkers
9
2026
4248
0.250
Why?
Oligoclonal Bands
1
2026
26
0.240
Why?
Herpesvirus 3, Human
3
2024
333
0.240
Why?
Neuroblastoma
3
1999
168
0.230
Why?
Aged, 80 and over
9
2026
8130
0.230
Why?
Stroke
3
2023
1219
0.230
Why?
Proteome
2
2024
510
0.230
Why?
Plasma
2
2024
227
0.230
Why?
Sodium Bicarbonate
1
2025
46
0.220
Why?
Humans
40
2026
143817
0.220
Why?
Protein Conformation
2
2005
933
0.220
Why?
Tetraspanin 28
1
2024
6
0.220
Why?
Intra-Abdominal Fat
1
2025
101
0.220
Why?
Chordoma
1
2024
17
0.220
Why?
DNA Transposable Elements
1
2025
121
0.210
Why?
Idiopathic Pulmonary Fibrosis
2
2024
681
0.210
Why?
alpha-Synuclein
1
2024
46
0.210
Why?
Acidosis
1
2025
105
0.210
Why?
Fluorescence Resonance Energy Transfer
1
2025
176
0.210
Why?
Amyloidogenic Proteins
1
2024
16
0.210
Why?
Mitochondria
2
2025
983
0.210
Why?
Aprotinin
1
2004
11
0.210
Why?
Varicella Zoster Virus Infection
2
2024
24
0.210
Why?
Vacuoles
1
2004
38
0.210
Why?
Osteoblasts
1
2024
144
0.210
Why?
Central Nervous System
1
2026
272
0.200
Why?
Glucocorticoids
3
1999
539
0.200
Why?
Recombinant Proteins
2
2007
1355
0.200
Why?
Carcinogenesis
1
2025
231
0.200
Why?
Animals
24
2025
38140
0.200
Why?
Tumor Microenvironment
2
2024
738
0.200
Why?
Neurodegenerative Diseases
1
2005
141
0.190
Why?
Bleomycin
1
2024
246
0.190
Why?
Cerebrovascular Circulation
1
2025
272
0.190
Why?
Epithelial-Mesenchymal Transition
1
2024
224
0.190
Why?
Diabetic Neuropathies
1
2023
97
0.180
Why?
Colon
1
2025
303
0.180
Why?
Apolipoprotein E4
1
2022
39
0.180
Why?
Ischemic Attack, Transient
1
2023
69
0.180
Why?
Disease
1
2003
98
0.180
Why?
Protein Processing, Post-Translational
4
2011
477
0.180
Why?
Fatty Acids
1
2025
450
0.180
Why?
Cognition
3
2025
1252
0.180
Why?
Carcinoma, Pancreatic Ductal
1
2025
307
0.180
Why?
Obesity
2
2025
3073
0.180
Why?
Aged
13
2026
25616
0.180
Why?
Bronchoalveolar Lavage Fluid
1
2024
644
0.180
Why?
Immunoglobulin G
1
2026
899
0.170
Why?
Endoplasmic Reticulum
1
2004
266
0.170
Why?
Retinal Drusen
1
2021
31
0.170
Why?
Peptides
2
2024
986
0.170
Why?
Virion
1
2022
115
0.170
Why?
Retinal Pigment Epithelium
1
2021
78
0.170
Why?
Aldosterone
4
1999
43
0.170
Why?
Arteritis
1
2021
25
0.170
Why?
Central Nervous System Viral Diseases
1
2022
77
0.170
Why?
Chemical Precipitation
1
2020
39
0.160
Why?
Cell Polarity
1
2021
139
0.160
Why?
Health Status
1
2026
821
0.160
Why?
Myelitis
1
2022
106
0.160
Why?
Brain-Derived Neurotrophic Factor
1
2021
147
0.160
Why?
Stem Cells
1
2025
622
0.160
Why?
Adipose Tissue
1
2025
656
0.160
Why?
Enterovirus D, Human
1
2022
87
0.160
Why?
Epigenesis, Genetic
1
2025
684
0.160
Why?
Amyloid
1
2021
95
0.160
Why?
Multiple Sclerosis
1
2026
482
0.160
Why?
Receptors, Chemokine
1
2000
48
0.160
Why?
Cell Movement
1
2024
973
0.160
Why?
Neuromuscular Diseases
1
2022
144
0.150
Why?
Inflammation
3
2026
2893
0.150
Why?
Chemokine CCL2
1
2000
115
0.150
Why?
Macular Degeneration
1
2021
190
0.150
Why?
Adrenal Cortex Hormones
3
1999
500
0.150
Why?
Enterovirus Infections
1
2022
174
0.150
Why?
Wnt-5a Protein
1
2018
25
0.150
Why?
Middle Aged
12
2026
35629
0.140
Why?
Fibroblasts
1
2024
1035
0.140
Why?
Renal Insufficiency, Chronic
1
2025
647
0.140
Why?
Signal Transduction
4
2021
5241
0.140
Why?
Cell Line, Tumor
5
2025
3609
0.140
Why?
Male
17
2026
71568
0.140
Why?
Frontotemporal Lobar Degeneration
1
2017
19
0.130
Why?
Kidney
2
2015
1483
0.130
Why?
Cell Communication
2
2000
325
0.130
Why?
N-Acetylneuraminic Acid
2
1999
16
0.130
Why?
Proteostasis Deficiencies
1
2017
5
0.130
Why?
Colorectal Neoplasms
1
2025
848
0.130
Why?
Melanoma
1
2024
806
0.130
Why?
Aneuploidy
1
2017
89
0.130
Why?
Pancreatic Neoplasms
1
2025
927
0.130
Why?
tau Proteins
1
2017
101
0.130
Why?
Tumor Cells, Cultured
5
2000
944
0.130
Why?
Female
16
2026
77569
0.130
Why?
Glycosylation
4
2026
173
0.120
Why?
Trisomy
1
2017
78
0.120
Why?
Brain Chemistry
1
1996
116
0.120
Why?
Proteins
1
2021
1023
0.110
Why?
Isoenzymes
1
1996
299
0.110
Why?
Endosomal Sorting Complexes Required for Transport
2
2025
46
0.110
Why?
Carcinoma, Hepatocellular
2
1997
370
0.110
Why?
Cystic Fibrosis
1
2005
1118
0.110
Why?
Rats
8
2025
5609
0.110
Why?
Apoptosis
3
2025
2446
0.110
Why?
Models, Biological
1
2003
1833
0.110
Why?
Neurofilament Proteins
2
2025
64
0.110
Why?
Molecular Sequence Data
5
2015
2914
0.100
Why?
Brain
4
2023
2901
0.100
Why?
Disease Models, Animal
4
2025
4553
0.100
Why?
Mice
10
2025
18421
0.100
Why?
Mitochondrial Proteins
1
2015
255
0.100
Why?
Oxidative Stress
2
2021
1377
0.100
Why?
Adult
7
2026
40128
0.090
Why?
Membrane Proteins
3
2024
1182
0.090
Why?
Enzyme Induction
3
1997
87
0.090
Why?
Nerve Tissue Proteins
1
1996
600
0.090
Why?
Amino Acid Sequence
3
2015
2148
0.090
Why?
Transcription Factor AP-2
1
2011
82
0.090
Why?
Glioma
1
1995
424
0.080
Why?
Parkinson Disease
1
2017
595
0.080
Why?
Ethanol
1
2015
626
0.080
Why?
Membrane Transport Proteins
1
2011
154
0.080
Why?
Mice, Inbred C57BL
4
2025
6032
0.080
Why?
Adrenalectomy
4
1999
71
0.080
Why?
Cells, Cultured
4
2021
4172
0.080
Why?
Receptors, Nicotinic
1
2011
326
0.070
Why?
Attitude of Health Personnel
1
2017
1174
0.070
Why?
Diabetes Mellitus, Type 2
1
2023
2590
0.070
Why?
Palliative Care
1
2017
982
0.070
Why?
Caregivers
1
2017
1025
0.070
Why?
Alcoholism
1
2015
814
0.070
Why?
DNA-Binding Proteins
2
2025
1493
0.070
Why?
Schizophrenia
1
2011
430
0.070
Why?
Saccharomyces cerevisiae Proteins
1
2011
406
0.060
Why?
Transcription Factors
2
2025
1735
0.060
Why?
Liver
1
1996
1846
0.060
Why?
Drug Stability
1
2007
165
0.060
Why?
Chemokine CXCL5
1
2026
19
0.060
Why?
DNA Primers
1
2007
516
0.060
Why?
Chemokine CXCL9
1
2026
38
0.060
Why?
Golgi Apparatus
2
2004
102
0.060
Why?
Polysaccharides
2
2004
89
0.060
Why?
Mutation
4
2017
4106
0.060
Why?
Ubiquitin Thiolesterase
1
2025
59
0.060
Why?
Middle Cerebral Artery
1
2025
55
0.060
Why?
Protein Aggregates
1
2026
84
0.060
Why?
Ultrasonography, Doppler, Transcranial
1
2025
46
0.060
Why?
Intercellular Signaling Peptides and Proteins
2
2024
382
0.060
Why?
Cytokines
2
2024
2093
0.060
Why?
DNA Methylation
2
2025
673
0.050
Why?
Case-Control Studies
2
2023
3614
0.050
Why?
Calnexin
1
2004
3
0.050
Why?
Centrifugation, Density Gradient
1
2004
40
0.050
Why?
Cycloheximide
1
2004
47
0.050
Why?
Concanavalin A
1
2004
71
0.050
Why?
Fluorescent Antibody Technique, Indirect
1
2004
46
0.050
Why?
Kinetics
2
1998
1622
0.050
Why?
Precipitin Tests
1
2004
95
0.050
Why?
Cell Death
1
2025
387
0.050
Why?
Mass Spectrometry
1
2007
747
0.050
Why?
Virus Activation
1
2024
92
0.050
Why?
Multienzyme Complexes
1
2004
64
0.050
Why?
Fluorescent Dyes
1
2025
327
0.050
Why?
Cysteine Endopeptidases
1
2004
74
0.050
Why?
Base Sequence
1
2007
2186
0.050
Why?
Protein Synthesis Inhibitors
1
2004
49
0.050
Why?
Intermediate Filaments
1
2023
26
0.050
Why?
Disulfides
1
2004
99
0.050
Why?
Glycolysis
1
2025
342
0.050
Why?
Time Factors
2
2025
7068
0.050
Why?
Sensory Receptor Cells
1
2024
101
0.050
Why?
Sucrose
1
2004
112
0.050
Why?
Diet, High-Fat
1
2025
262
0.050
Why?
Hippocampus
2
2022
968
0.050
Why?
Chemokines, CXC
1
2003
70
0.050
Why?
Fungal Proteins
1
2004
145
0.050
Why?
Carbohydrate Sequence
3
1999
29
0.050
Why?
Neurites
1
2023
50
0.050
Why?
Diffusion Tensor Imaging
1
2023
74
0.050
Why?
beta Catenin
1
2025
253
0.050
Why?
Plasmids
1
2004
376
0.050
Why?
Imipramine
1
2022
11
0.050
Why?
Interferon-gamma
1
2026
791
0.050
Why?
Growth Disorders
1
2022
85
0.050
Why?
Wnt Signaling Pathway
1
2024
212
0.050
Why?
Chemokines
1
2003
224
0.050
Why?
Hearing Loss, Sensorineural
1
2022
69
0.050
Why?
Densitometry
1
2022
38
0.050
Why?
Gene Expression Regulation
1
2011
2620
0.050
Why?
Retinal Ganglion Cells
1
2003
121
0.050
Why?
Diffusion Magnetic Resonance Imaging
1
2023
155
0.040
Why?
Transforming Growth Factor beta
1
2024
481
0.040
Why?
Virus Internalization
1
2022
66
0.040
Why?
Polymerization
1
2022
131
0.040
Why?
Viral Proteins
1
2024
365
0.040
Why?
Protein Structure, Tertiary
1
2004
857
0.040
Why?
Catalysis
1
2022
326
0.040
Why?
Cattle
1
2004
1004
0.040
Why?
Lectins
2
1998
44
0.040
Why?
Chromatin
1
2025
554
0.040
Why?
Mice, Knockout
2
2025
3120
0.040
Why?
Oxidation-Reduction
1
2025
1096
0.040
Why?
Interneurons
1
2022
127
0.040
Why?
Receptors, HIV
1
2000
24
0.040
Why?
Tissue Plasminogen Activator
1
2023
238
0.040
Why?
Neuroimaging
1
2023
286
0.040
Why?
Immune System
1
2022
182
0.040
Why?
DNA, Complementary
1
2021
278
0.040
Why?
Retina
1
2003
321
0.040
Why?
Double-Blind Method
1
2025
2017
0.040
Why?
Insulin-Like Growth Factor I
1
2022
320
0.040
Why?
Sensitivity and Specificity
1
2025
1984
0.040
Why?
Teratocarcinoma
1
2000
2
0.040
Why?
Receptors, Dopamine D2
1
2000
92
0.040
Why?
Organoids
1
2021
135
0.040
Why?
Intracellular Space
1
2020
67
0.040
Why?
Phagocytosis
1
2021
297
0.040
Why?
Acyclovir
1
2020
96
0.040
Why?
Pilot Projects
1
2025
1851
0.040
Why?
Extracellular Space
1
2020
132
0.040
Why?
Phytohemagglutinins
1
1999
29
0.040
Why?
Viral Envelope Proteins
1
2020
99
0.040
Why?
Cerebral Palsy
1
2021
127
0.040
Why?
Cell Line
2
2022
2906
0.040
Why?
Thrombosis
1
2023
393
0.040
Why?
DNA, Viral
1
2021
361
0.040
Why?
Nicotine
1
2021
331
0.040
Why?
Genotype
1
2004
1837
0.040
Why?
Reactive Oxygen Species
1
2021
645
0.040
Why?
Biomarkers, Tumor
1
2025
1327
0.040
Why?
Induced Pluripotent Stem Cells
1
2021
276
0.040
Why?
Receptors, G-Protein-Coupled
1
2000
232
0.040
Why?
RNA, Messenger
2
2011
2847
0.030
Why?
Gene Expression Regulation, Neoplastic
1
2024
1496
0.030
Why?
Asialoglycoproteins
1
1997
2
0.030
Why?
Fetuins
1
1997
3
0.030
Why?
Cytidine Monophosphate N-Acetylneuraminic Acid
1
1997
3
0.030
Why?
MicroRNAs
1
2024
699
0.030
Why?
Calcium Signaling
1
2000
251
0.030
Why?
Nervous System
1
1998
70
0.030
Why?
alpha-Fetoproteins
1
1997
40
0.030
Why?
Protein Binding
1
2004
2261
0.030
Why?
Homozygote
1
2017
201
0.030
Why?
Gene Dosage
1
2017
148
0.030
Why?
Tretinoin
1
1998
124
0.030
Why?
Chromosomes, Human, Pair 21
1
2017
42
0.030
Why?
Heterozygote
1
2017
315
0.030
Why?
Carbohydrate Conformation
1
1996
15
0.030
Why?
Glycoproteins
1
1998
357
0.030
Why?
Oligosaccharides
1
1996
59
0.030
Why?
Parietal Lobe
1
1996
60
0.030
Why?
Glutathione Reductase
1
2015
25
0.030
Why?
Peroxiredoxins
1
2015
26
0.030
Why?
Substrate Specificity
1
1996
379
0.030
Why?
Brain Stem
1
1996
96
0.030
Why?
Glutathione Transferase
1
2015
99
0.030
Why?
Fetus
1
2000
800
0.030
Why?
Adolescent
2
2025
22233
0.030
Why?
Nervous System Diseases
1
1998
280
0.030
Why?
Acetylation
1
2015
245
0.030
Why?
Aldehydes
1
2015
144
0.030
Why?
Oxidative Phosphorylation
1
2015
210
0.030
Why?
Focus Groups
1
2017
573
0.030
Why?
Academic Medical Centers
1
2017
537
0.030
Why?
Antiviral Agents
1
2020
743
0.030
Why?
Cerebellum
1
1996
222
0.030
Why?
Risk Assessment
1
2023
3556
0.020
Why?
Glutathione
1
2015
379
0.020
Why?
Interviews as Topic
1
2017
884
0.020
Why?
Cell Differentiation
2
1998
2045
0.020
Why?
Superoxide Dismutase
1
2015
349
0.020
Why?
Mice, Transgenic
1
2017
2182
0.020
Why?
Neoplasm Proteins
1
1995
443
0.020
Why?
Lipid Metabolism
1
2015
524
0.020
Why?
Risk Factors
1
2026
10623
0.020
Why?
SEC Translocation Channels
1
2011
10
0.020
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2011
93
0.020
Why?
Amino Acids
1
2015
519
0.020
Why?
Lung
1
2024
4143
0.020
Why?
Mutagenesis, Site-Directed
1
2011
379
0.020
Why?
Protein Stability
1
2011
177
0.020
Why?
Hydrophobic and Hydrophilic Interactions
1
2011
192
0.020
Why?
Child, Preschool
1
2025
11631
0.020
Why?
Genetic Vectors
1
2011
342
0.020
Why?
Cross-Sectional Studies
1
2021
5761
0.020
Why?
HeLa Cells
1
2011
653
0.020
Why?
Protein Transport
1
2011
445
0.020
Why?
Qualitative Research
1
2017
1626
0.020
Why?
RNA, Small Interfering
1
2011
645
0.020
Why?
Young Adult
1
2025
13914
0.020
Why?
Treatment Outcome
1
2023
11459
0.020
Why?
Promoter Regions, Genetic
1
2011
1255
0.020
Why?
Antineoplastic Agents
1
1998
2220
0.020
Why?
Child
1
2025
22441
0.010
Why?
Transcription, Genetic
1
2011
1504
0.010
Why?
Retrospective Studies
1
2022
16755
0.010
Why?
In Situ Nick-End Labeling
1
2003
123
0.010
Why?
Chick Embryo
1
2003
134
0.010
Why?
Glycogen Synthase Kinase 3 beta
1
2003
73
0.010
Why?
Glycogen Synthase Kinase 3
1
2003
81
0.010
Why?
Chemokine CXCL12
1
2003
89
0.010
Why?
Nerve Growth Factors
1
2003
78
0.010
Why?
Receptors, CXCR4
1
2003
91
0.010
Why?
Infant
1
2017
9886
0.010
Why?
Cell Count
1
2003
324
0.010
Why?
Cyclic AMP
1
2003
209
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2003
126
0.010
Why?
Mitogen-Activated Protein Kinases
1
2003
298
0.010
Why?
Apelin Receptors
1
2000
4
0.010
Why?
Dopamine D2 Receptor Antagonists
1
2000
5
0.010
Why?
Apelin
1
2000
10
0.010
Why?
Adipokines
1
2000
58
0.010
Why?
Receptors, Virus
1
2000
96
0.010
Why?
Simian Immunodeficiency Virus
1
2000
92
0.010
Why?
Cell Survival
1
2003
1110
0.010
Why?
Primates
1
2000
132
0.010
Why?
Swainsonine
1
1999
1
0.010
Why?
1-Deoxynojirimycin
1
1999
1
0.010
Why?
Mannosidases
1
1999
4
0.010
Why?
Neuraminidase
1
1999
25
0.010
Why?
Tissue Distribution
1
1999
328
0.010
Why?
Phosphorylation
1
2003
1761
0.010
Why?
Transfection
1
2000
952
0.010
Why?
Biological Transport
1
1999
412
0.010
Why?
Leukocytes, Mononuclear
1
2000
580
0.010
Why?
Mice, Inbred BALB C
1
2000
1270
0.010
Why?
Solubility
1
1998
239
0.010
Why?
Blotting, Western
1
1999
1207
0.010
Why?
Pituitary Neoplasms
1
1999
191
0.010
Why?
Carrier Proteins
1
2000
750
0.010
Why?
HIV-1
1
2000
904
0.010
Why?
Antibodies, Monoclonal
1
2000
1522
0.010
Why?
T-Lymphocytes
1
2000
2041
0.010
Why?
Coughlan's Networks
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