Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christina Coughlan

Concepts (338)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Alzheimer Disease
9
2025
560
2.160
Why?
Extracellular Vesicles
7
2025
146
1.780
Why?
Exosomes
3
2023
103
0.840
Why?
Astrocytes
4
2022
210
0.820
Why?
White Matter
2
2023
145
0.780
Why?
Gliosis
2
2023
28
0.750
Why?
Proteasome Endopeptidase Complex
2
2022
156
0.750
Why?
Sialyltransferases
8
1999
13
0.730
Why?
Amyloid beta-Protein Precursor
5
2022
66
0.690
Why?
Healthy Aging
1
2021
35
0.680
Why?
Glial Fibrillary Acidic Protein
1
2021
100
0.680
Why?
Ultracentrifugation
1
2020
52
0.670
Why?
Memory, Episodic
1
2021
52
0.670
Why?
Saccharomyces cerevisiae
5
2022
557
0.560
Why?
Amyloid beta-Peptides
5
2022
220
0.510
Why?
Proteomics
3
2024
1111
0.480
Why?
Peptide Fragments
3
2022
706
0.480
Why?
Cognitive Dysfunction
3
2025
383
0.450
Why?
Nanoparticles
1
2020
482
0.450
Why?
Dexamethasone
7
1999
370
0.410
Why?
Brain Ischemia
2
2025
338
0.340
Why?
Neurons
6
2022
1590
0.330
Why?
Herpes Zoster
3
2024
316
0.330
Why?
Islet Amyloid Polypeptide
2
2021
47
0.330
Why?
Down Syndrome
4
2022
497
0.330
Why?
Sialoglycoproteins
3
1997
159
0.290
Why?
Protein Folding
3
2005
280
0.280
Why?
Neuroblastoma
3
1999
160
0.250
Why?
Herpesvirus 3, Human
3
2024
332
0.250
Why?
Stroke
3
2023
1120
0.240
Why?
Proteome
2
2024
472
0.240
Why?
Plasma
2
2024
212
0.240
Why?
Sodium Bicarbonate
1
2025
45
0.230
Why?
Tetraspanin 28
1
2024
6
0.230
Why?
Chordoma
1
2024
14
0.230
Why?
Protein Conformation
2
2005
934
0.230
Why?
DNA Transposable Elements
1
2025
121
0.220
Why?
Idiopathic Pulmonary Fibrosis
2
2024
657
0.220
Why?
alpha-Synuclein
1
2024
35
0.220
Why?
Mitochondria
2
2025
948
0.220
Why?
Acidosis
1
2025
101
0.220
Why?
Amyloidogenic Proteins
1
2024
16
0.220
Why?
Aprotinin
1
2004
9
0.220
Why?
Varicella Zoster Virus Infection
2
2024
24
0.220
Why?
Vacuoles
1
2004
40
0.210
Why?
Osteoblasts
1
2024
126
0.210
Why?
Interleukin-6
2
2025
778
0.210
Why?
Recombinant Proteins
2
2007
1356
0.210
Why?
Glucocorticoids
3
1999
596
0.210
Why?
Tumor Microenvironment
2
2024
676
0.210
Why?
Neurodegenerative Diseases
1
2005
135
0.200
Why?
Humans
35
2025
137782
0.200
Why?
Cerebrovascular Circulation
1
2025
250
0.200
Why?
Bleomycin
1
2024
248
0.200
Why?
Epithelial-Mesenchymal Transition
1
2024
209
0.200
Why?
Aged, 80 and over
7
2025
7637
0.190
Why?
Colon
1
2025
282
0.190
Why?
Diabetic Neuropathies
1
2023
94
0.190
Why?
Cognition
3
2025
1157
0.190
Why?
Ischemic Attack, Transient
1
2023
65
0.190
Why?
Apolipoprotein E4
1
2022
37
0.190
Why?
Protein Processing, Post-Translational
4
2011
465
0.190
Why?
Disease
1
2003
98
0.190
Why?
Fatty Acids
1
2025
443
0.180
Why?
Animals
22
2025
36951
0.180
Why?
Bronchoalveolar Lavage Fluid
1
2024
652
0.180
Why?
Retinal Drusen
1
2021
31
0.180
Why?
Endoplasmic Reticulum
1
2004
265
0.180
Why?
Virion
1
2022
93
0.180
Why?
Peptides
2
2024
985
0.180
Why?
Retinal Pigment Epithelium
1
2021
77
0.180
Why?
Aldosterone
4
1999
45
0.180
Why?
Arteritis
1
2021
28
0.170
Why?
Biomarkers
6
2025
4154
0.170
Why?
Central Nervous System Viral Diseases
1
2022
79
0.170
Why?
Brain-Derived Neurotrophic Factor
1
2021
131
0.170
Why?
Chemical Precipitation
1
2020
37
0.170
Why?
Cell Polarity
1
2021
141
0.170
Why?
Adipose Tissue
1
2025
635
0.170
Why?
Stem Cells
1
2025
594
0.170
Why?
Myelitis
1
2022
107
0.170
Why?
Epigenesis, Genetic
1
2025
660
0.170
Why?
Amyloid
1
2021
87
0.170
Why?
Enterovirus D, Human
1
2022
88
0.170
Why?
Cell Movement
1
2024
967
0.160
Why?
Neuromuscular Diseases
1
2022
132
0.160
Why?
Receptors, Chemokine
1
2000
47
0.160
Why?
Macular Degeneration
1
2021
164
0.160
Why?
Aged
11
2025
24001
0.160
Why?
Chemokine CCL2
1
2000
115
0.160
Why?
Fibroblasts
1
2024
996
0.150
Why?
Enterovirus Infections
1
2022
177
0.150
Why?
Wnt-5a Protein
1
2018
23
0.150
Why?
Renal Insufficiency, Chronic
1
2025
617
0.150
Why?
Adrenal Cortex Hormones
3
1999
565
0.150
Why?
Signal Transduction
4
2021
5081
0.150
Why?
Frontotemporal Lobar Degeneration
1
2017
18
0.140
Why?
Cell Communication
2
2000
315
0.140
Why?
Kidney
2
2015
1475
0.140
Why?
N-Acetylneuraminic Acid
2
1999
12
0.140
Why?
Proteostasis Deficiencies
1
2017
5
0.140
Why?
Aneuploidy
1
2017
90
0.140
Why?
Melanoma
1
2024
760
0.140
Why?
tau Proteins
1
2017
90
0.130
Why?
Tumor Cells, Cultured
5
2000
955
0.130
Why?
Trisomy
1
2017
80
0.130
Why?
Brain Chemistry
1
1996
117
0.120
Why?
Carcinoma, Hepatocellular
2
1997
362
0.120
Why?
Proteins
1
2021
1009
0.120
Why?
Isoenzymes
1
1996
304
0.120
Why?
Models, Biological
1
2003
1783
0.120
Why?
Aging
2
2025
1865
0.120
Why?
Cystic Fibrosis
1
2005
1114
0.120
Why?
Male
13
2025
67906
0.110
Why?
Brain
4
2023
2677
0.110
Why?
Molecular Sequence Data
5
2015
2900
0.110
Why?
Middle Aged
8
2025
33554
0.100
Why?
Oxidative Stress
2
2021
1317
0.100
Why?
Mitochondrial Proteins
1
2015
257
0.100
Why?
Female
12
2025
73465
0.100
Why?
Membrane Proteins
3
2024
1164
0.100
Why?
Enzyme Induction
3
1997
90
0.100
Why?
Nerve Tissue Proteins
1
1996
596
0.090
Why?
Obesity
1
2025
2993
0.090
Why?
Amino Acid Sequence
3
2015
2139
0.090
Why?
Transcription Factor AP-2
1
2011
82
0.090
Why?
Parkinson Disease
1
2017
498
0.090
Why?
Glioma
1
1995
395
0.090
Why?
Mice
9
2025
17794
0.090
Why?
Ethanol
1
2015
608
0.080
Why?
Palliative Care
1
2017
758
0.080
Why?
Rats
7
1999
5648
0.080
Why?
Mice, Inbred C57BL
4
2025
5764
0.080
Why?
Membrane Transport Proteins
1
2011
162
0.080
Why?
Adrenalectomy
4
1999
68
0.080
Why?
Apoptosis
2
2017
2553
0.080
Why?
Cells, Cultured
4
2021
4193
0.080
Why?
Cell Line, Tumor
3
2024
3415
0.080
Why?
Caregivers
1
2017
888
0.080
Why?
Disease Models, Animal
3
2025
4295
0.080
Why?
Attitude of Health Personnel
1
2017
1172
0.080
Why?
Receptors, Nicotinic
1
2011
334
0.080
Why?
Diabetes Mellitus, Type 2
1
2023
2534
0.080
Why?
Alcoholism
1
2015
809
0.070
Why?
Glycosylation
3
1999
151
0.070
Why?
Schizophrenia
1
2011
439
0.070
Why?
Saccharomyces cerevisiae Proteins
1
2011
405
0.070
Why?
Liver
1
1996
1943
0.070
Why?
Drug Stability
1
2007
167
0.070
Why?
DNA Primers
1
2007
515
0.060
Why?
Adult
4
2024
38023
0.060
Why?
Golgi Apparatus
2
2004
100
0.060
Why?
Polysaccharides
2
2004
79
0.060
Why?
Mutation
4
2017
3959
0.060
Why?
Ultrasonography, Doppler, Transcranial
1
2025
45
0.060
Why?
Middle Cerebral Artery
1
2025
53
0.060
Why?
Intercellular Signaling Peptides and Proteins
2
2024
382
0.060
Why?
Cytokines
2
2024
2085
0.060
Why?
Endosomal Sorting Complexes Required for Transport
1
2025
38
0.060
Why?
DNA Methylation
2
2025
643
0.060
Why?
Case-Control Studies
2
2023
3569
0.060
Why?
Calnexin
1
2004
3
0.050
Why?
Centrifugation, Density Gradient
1
2004
41
0.050
Why?
Cycloheximide
1
2004
55
0.050
Why?
Concanavalin A
1
2004
76
0.050
Why?
Fluorescent Antibody Technique, Indirect
1
2004
51
0.050
Why?
Kinetics
2
1998
1670
0.050
Why?
Precipitin Tests
1
2004
100
0.050
Why?
Mass Spectrometry
1
2007
739
0.050
Why?
Virus Activation
1
2024
88
0.050
Why?
Multienzyme Complexes
1
2004
68
0.050
Why?
Hippocampus
2
2022
895
0.050
Why?
Cysteine Endopeptidases
1
2004
73
0.050
Why?
Protein Synthesis Inhibitors
1
2004
47
0.050
Why?
Time Factors
2
2025
6834
0.050
Why?
Base Sequence
1
2007
2181
0.050
Why?
Intermediate Filaments
1
2023
28
0.050
Why?
Diet, High-Fat
1
2025
247
0.050
Why?
Disulfides
1
2004
107
0.050
Why?
Sensory Receptor Cells
1
2024
98
0.050
Why?
Fungal Proteins
1
2004
123
0.050
Why?
Sucrose
1
2004
110
0.050
Why?
Neurites
1
2023
48
0.050
Why?
Chemokines, CXC
1
2003
70
0.050
Why?
Carbohydrate Sequence
3
1999
27
0.050
Why?
Neurofilament Proteins
1
2023
52
0.050
Why?
Diffusion Tensor Imaging
1
2023
79
0.050
Why?
beta Catenin
1
2025
253
0.050
Why?
Plasmids
1
2004
363
0.050
Why?
Imipramine
1
2022
12
0.050
Why?
Wnt Signaling Pathway
1
2024
192
0.050
Why?
Growth Disorders
1
2022
86
0.050
Why?
Retinal Ganglion Cells
1
2003
110
0.050
Why?
Hearing Loss, Sensorineural
1
2022
67
0.050
Why?
Chemokines
1
2003
228
0.050
Why?
Densitometry
1
2022
38
0.050
Why?
Gene Expression Regulation
1
2011
2607
0.050
Why?
Virus Internalization
1
2022
49
0.050
Why?
Diffusion Magnetic Resonance Imaging
1
2023
154
0.050
Why?
Transforming Growth Factor beta
1
2024
483
0.050
Why?
Viral Proteins
1
2024
342
0.050
Why?
Polymerization
1
2022
124
0.050
Why?
Catalysis
1
2022
307
0.040
Why?
Protein Structure, Tertiary
1
2004
861
0.040
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
1
2022
152
0.040
Why?
Oxidation-Reduction
1
2025
1060
0.040
Why?
Cattle
1
2004
985
0.040
Why?
Neuroimaging
1
2023
260
0.040
Why?
Tissue Plasminogen Activator
1
2023
225
0.040
Why?
Lectins
2
1998
49
0.040
Why?
Interneurons
1
2022
122
0.040
Why?
Receptors, HIV
1
2000
24
0.040
Why?
Retina
1
2003
298
0.040
Why?
DNA, Complementary
1
2021
272
0.040
Why?
Immune System
1
2022
177
0.040
Why?
Organoids
1
2021
112
0.040
Why?
Double-Blind Method
1
2025
1997
0.040
Why?
Sensitivity and Specificity
1
2025
1946
0.040
Why?
Insulin-Like Growth Factor I
1
2022
319
0.040
Why?
Teratocarcinoma
1
2000
2
0.040
Why?
Pilot Projects
1
2025
1713
0.040
Why?
Receptors, Dopamine D2
1
2000
97
0.040
Why?
Intracellular Space
1
2020
68
0.040
Why?
Extracellular Space
1
2020
119
0.040
Why?
Acyclovir
1
2020
101
0.040
Why?
Phagocytosis
1
2021
382
0.040
Why?
Cerebral Palsy
1
2021
110
0.040
Why?
Phytohemagglutinins
1
1999
30
0.040
Why?
Viral Envelope Proteins
1
2020
84
0.040
Why?
Thrombosis
1
2023
371
0.040
Why?
Cell Line
2
2022
2847
0.040
Why?
DNA, Viral
1
2021
364
0.040
Why?
Nicotine
1
2021
334
0.040
Why?
Reactive Oxygen Species
1
2021
623
0.040
Why?
Induced Pluripotent Stem Cells
1
2021
248
0.040
Why?
Genotype
1
2004
1917
0.040
Why?
Receptors, G-Protein-Coupled
1
2000
220
0.040
Why?
Gene Expression Regulation, Neoplastic
1
2024
1396
0.040
Why?
RNA, Messenger
2
2011
2834
0.040
Why?
Fetuins
1
1997
2
0.030
Why?
Asialoglycoproteins
1
1997
2
0.030
Why?
Cytidine Monophosphate N-Acetylneuraminic Acid
1
1997
3
0.030
Why?
Nervous System
1
1998
67
0.030
Why?
Calcium Signaling
1
2000
249
0.030
Why?
MicroRNAs
1
2024
692
0.030
Why?
Protein Binding
1
2004
2224
0.030
Why?
DNA-Binding Proteins
1
2025
1502
0.030
Why?
alpha-Fetoproteins
1
1997
46
0.030
Why?
Homozygote
1
2017
203
0.030
Why?
Gene Dosage
1
2017
140
0.030
Why?
Tretinoin
1
1998
123
0.030
Why?
Chromosomes, Human, Pair 21
1
2017
44
0.030
Why?
Heterozygote
1
2017
293
0.030
Why?
Transcription Factors
1
2025
1719
0.030
Why?
Carbohydrate Conformation
1
1996
11
0.030
Why?
Glycoproteins
1
1998
342
0.030
Why?
Oligosaccharides
1
1996
60
0.030
Why?
Glutathione Reductase
1
2015
25
0.030
Why?
Parietal Lobe
1
1996
58
0.030
Why?
Peroxiredoxins
1
2015
24
0.030
Why?
Substrate Specificity
1
1996
372
0.030
Why?
Brain Stem
1
1996
94
0.030
Why?
Glutathione Transferase
1
2015
106
0.030
Why?
Fetus
1
2000
806
0.030
Why?
Nervous System Diseases
1
1998
266
0.030
Why?
Acetylation
1
2015
248
0.030
Why?
Aldehydes
1
2015
145
0.030
Why?
Oxidative Phosphorylation
1
2015
193
0.030
Why?
Focus Groups
1
2017
530
0.030
Why?
Academic Medical Centers
1
2017
512
0.030
Why?
Antiviral Agents
1
2020
744
0.030
Why?
Cerebellum
1
1996
224
0.030
Why?
Interviews as Topic
1
2017
797
0.030
Why?
Glutathione
1
2015
356
0.030
Why?
Risk Assessment
1
2023
3461
0.030
Why?
Cell Differentiation
2
1998
1991
0.030
Why?
Superoxide Dismutase
1
2015
346
0.030
Why?
Mice, Transgenic
1
2017
2167
0.020
Why?
Neoplasm Proteins
1
1995
434
0.020
Why?
Lipid Metabolism
1
2015
518
0.020
Why?
SEC Translocation Channels
1
2011
10
0.020
Why?
Amino Acids
1
2015
497
0.020
Why?
Lung
1
2024
4060
0.020
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2011
97
0.020
Why?
Inflammation
1
2022
2838
0.020
Why?
Mutagenesis, Site-Directed
1
2011
375
0.020
Why?
Protein Stability
1
2011
176
0.020
Why?
Hydrophobic and Hydrophilic Interactions
1
2011
187
0.020
Why?
Genetic Vectors
1
2011
319
0.020
Why?
Cross-Sectional Studies
1
2021
5478
0.020
Why?
Qualitative Research
1
2017
1399
0.020
Why?
HeLa Cells
1
2011
636
0.020
Why?
Protein Transport
1
2011
445
0.020
Why?
RNA, Small Interfering
1
2011
622
0.020
Why?
Treatment Outcome
1
2023
10837
0.020
Why?
Promoter Regions, Genetic
1
2011
1251
0.020
Why?
Antineoplastic Agents
1
1998
2129
0.020
Why?
Transcription, Genetic
1
2011
1457
0.010
Why?
Retrospective Studies
1
2022
15682
0.010
Why?
Adolescent
1
2023
21574
0.010
Why?
In Situ Nick-End Labeling
1
2003
124
0.010
Why?
Chick Embryo
1
2003
130
0.010
Why?
Glycogen Synthase Kinase 3 beta
1
2003
72
0.010
Why?
Chemokine CXCL12
1
2003
81
0.010
Why?
Infant
1
2017
9482
0.010
Why?
Glycogen Synthase Kinase 3
1
2003
82
0.010
Why?
Receptors, CXCR4
1
2003
86
0.010
Why?
Nerve Growth Factors
1
2003
79
0.010
Why?
Cell Count
1
2003
324
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2003
136
0.010
Why?
Cyclic AMP
1
2003
234
0.010
Why?
Mitogen-Activated Protein Kinases
1
2003
313
0.010
Why?
Apelin Receptors
1
2000
4
0.010
Why?
Dopamine D2 Receptor Antagonists
1
2000
5
0.010
Why?
Apelin
1
2000
10
0.010
Why?
Adipokines
1
2000
49
0.010
Why?
Receptors, Virus
1
2000
83
0.010
Why?
Simian Immunodeficiency Virus
1
2000
88
0.010
Why?
Cell Survival
1
2003
1120
0.010
Why?
Primates
1
2000
126
0.010
Why?
Swainsonine
1
1999
1
0.010
Why?
1-Deoxynojirimycin
1
1999
1
0.010
Why?
Mannosidases
1
1999
4
0.010
Why?
Neuraminidase
1
1999
24
0.010
Why?
Tissue Distribution
1
1999
332
0.010
Why?
Phosphorylation
1
2003
1759
0.010
Why?
Transfection
1
2000
945
0.010
Why?
Biological Transport
1
1999
418
0.010
Why?
Leukocytes, Mononuclear
1
2000
558
0.010
Why?
Mice, Inbred BALB C
1
2000
1272
0.010
Why?
Solubility
1
1998
245
0.010
Why?
Pituitary Neoplasms
1
1999
190
0.010
Why?
Blotting, Western
1
1999
1227
0.010
Why?
Carrier Proteins
1
2000
771
0.010
Why?
Mice, Knockout
1
2003
3018
0.010
Why?
HIV-1
1
2000
864
0.010
Why?
Antibodies, Monoclonal
1
2000
1430
0.010
Why?
T-Lymphocytes
1
2000
1998
0.010
Why?
Coughlan's Networks
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