Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christina Coughlan

Concepts (364)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Alzheimer Disease
11
2026
630
2.280
Why?
Extracellular Vesicles
9
2025
171
2.030
Why?
Exosomes
3
2023
104
0.800
Why?
Astrocytes
4
2022
228
0.770
Why?
Glial Fibrillary Acidic Protein
3
2026
122
0.750
Why?
White Matter
2
2023
155
0.740
Why?
Gliosis
2
2023
30
0.710
Why?
Proteasome Endopeptidase Complex
2
2022
155
0.710
Why?
Sialyltransferases
8
1999
13
0.690
Why?
Amyloid beta-Protein Precursor
5
2022
64
0.660
Why?
Ultracentrifugation
1
2020
50
0.640
Why?
Healthy Aging
1
2021
44
0.640
Why?
Memory, Episodic
1
2021
57
0.640
Why?
Amyloid beta-Peptides
7
2026
245
0.580
Why?
Neurons
8
2026
1652
0.560
Why?
Saccharomyces cerevisiae
5
2022
574
0.540
Why?
Proteomics
4
2026
1188
0.490
Why?
Peptide Fragments
3
2022
696
0.460
Why?
Nanoparticles
1
2020
517
0.410
Why?
Cognitive Dysfunction
3
2025
468
0.400
Why?
Neurodegenerative Diseases
2
2026
143
0.400
Why?
Dexamethasone
7
1999
365
0.390
Why?
Biomarkers
10
2026
4302
0.350
Why?
Brain Ischemia
2
2025
359
0.320
Why?
Herpes Zoster
3
2024
319
0.310
Why?
Islet Amyloid Polypeptide
2
2021
48
0.310
Why?
Down Syndrome
4
2022
525
0.310
Why?
Sialoglycoproteins
3
1997
157
0.270
Why?
Protein Folding
3
2005
277
0.260
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
2
2025
161
0.250
Why?
Aging
4
2026
1973
0.250
Why?
Interleukin-6
3
2026
779
0.240
Why?
Oligoclonal Bands
1
2026
26
0.230
Why?
Herpesvirus 3, Human
3
2024
343
0.230
Why?
Neuroblastoma
3
1999
174
0.230
Why?
Aged, 80 and over
9
2026
8346
0.230
Why?
Plasma
2
2024
223
0.220
Why?
Proteome
2
2024
513
0.220
Why?
Stroke
3
2023
1271
0.220
Why?
Humans
41
2026
145763
0.220
Why?
Sodium Bicarbonate
1
2025
48
0.220
Why?
Protein Conformation
2
2005
938
0.220
Why?
Tetraspanin 28
1
2024
6
0.220
Why?
Intra-Abdominal Fat
1
2025
101
0.210
Why?
Chordoma
1
2024
17
0.210
Why?
DNA Transposable Elements
1
2025
124
0.210
Why?
Acidosis
1
2025
105
0.210
Why?
alpha-Synuclein
1
2024
46
0.210
Why?
Idiopathic Pulmonary Fibrosis
2
2024
692
0.210
Why?
Fluorescence Resonance Energy Transfer
1
2025
179
0.210
Why?
Amyloidogenic Proteins
1
2024
16
0.210
Why?
Aprotinin
1
2004
9
0.210
Why?
Mitochondria
2
2025
992
0.200
Why?
Vacuoles
1
2004
38
0.200
Why?
Osteoblasts
1
2024
145
0.200
Why?
Varicella Zoster Virus Infection
2
2024
29
0.200
Why?
Glucocorticoids
3
1999
532
0.200
Why?
Carcinogenesis
1
2025
228
0.200
Why?
Recombinant Proteins
2
2007
1368
0.200
Why?
Central Nervous System
1
2026
282
0.200
Why?
Animals
24
2025
38097
0.200
Why?
Tumor Microenvironment
2
2024
735
0.190
Why?
Bleomycin
1
2024
255
0.190
Why?
Epithelial-Mesenchymal Transition
1
2024
220
0.190
Why?
Cerebrovascular Circulation
1
2025
290
0.190
Why?
Colon
1
2025
309
0.180
Why?
Diabetic Neuropathies
1
2023
100
0.180
Why?
tau Proteins
2
2026
105
0.180
Why?
Ischemic Attack, Transient
1
2023
71
0.180
Why?
Apolipoprotein E4
1
2022
42
0.180
Why?
Disease
1
2003
96
0.180
Why?
Carcinoma, Pancreatic Ductal
1
2025
293
0.180
Why?
Protein Processing, Post-Translational
4
2011
473
0.180
Why?
Fatty Acids
1
2025
457
0.170
Why?
Bronchoalveolar Lavage Fluid
1
2024
638
0.170
Why?
Cognition
3
2025
1271
0.170
Why?
Immunoglobulin G
1
2026
892
0.170
Why?
Obesity
2
2025
3118
0.170
Why?
Endoplasmic Reticulum
1
2004
264
0.170
Why?
Aged
13
2026
26215
0.170
Why?
Retinal Drusen
1
2021
31
0.170
Why?
Virion
1
2022
108
0.170
Why?
Peptides
2
2024
998
0.170
Why?
Retinal Pigment Epithelium
1
2021
79
0.170
Why?
Arteritis
1
2021
23
0.170
Why?
Aldosterone
4
1999
42
0.170
Why?
Central Nervous System Viral Diseases
1
2022
78
0.160
Why?
Chemical Precipitation
1
2020
39
0.160
Why?
Cell Polarity
1
2021
137
0.160
Why?
Health Status
1
2026
835
0.160
Why?
Myelitis
1
2022
107
0.160
Why?
Neurofilament Proteins
3
2026
79
0.160
Why?
Brain-Derived Neurotrophic Factor
1
2021
154
0.160
Why?
Adipose Tissue
1
2025
645
0.160
Why?
Epigenesis, Genetic
1
2025
693
0.160
Why?
Enterovirus D, Human
1
2022
87
0.160
Why?
Stem Cells
1
2025
630
0.160
Why?
Multiple Sclerosis
1
2026
489
0.160
Why?
Amyloid
1
2021
96
0.160
Why?
Cell Movement
1
2024
961
0.150
Why?
Middle Aged
13
2026
36302
0.150
Why?
Receptors, Chemokine
1
2000
48
0.150
Why?
Neuromuscular Diseases
1
2022
145
0.150
Why?
Inflammation
3
2026
2883
0.150
Why?
Chemokine CCL2
1
2000
112
0.150
Why?
Adrenal Cortex Hormones
3
1999
484
0.150
Why?
Macular Degeneration
1
2021
191
0.150
Why?
Enterovirus Infections
1
2022
173
0.150
Why?
Male
18
2026
73003
0.140
Why?
Wnt-5a Protein
1
2018
25
0.140
Why?
Fibroblasts
1
2024
1027
0.140
Why?
Signal Transduction
4
2021
5223
0.140
Why?
Renal Insufficiency, Chronic
1
2025
668
0.140
Why?
Cell Line, Tumor
5
2025
3551
0.140
Why?
Frontotemporal Lobar Degeneration
1
2017
18
0.130
Why?
Melanoma
1
2024
761
0.130
Why?
Female
17
2026
79035
0.130
Why?
Kidney
2
2015
1496
0.130
Why?
Cell Communication
2
2000
327
0.130
Why?
N-Acetylneuraminic Acid
2
1999
16
0.130
Why?
Proteostasis Deficiencies
1
2017
5
0.130
Why?
Colorectal Neoplasms
1
2025
868
0.130
Why?
Aneuploidy
1
2017
91
0.130
Why?
Pancreatic Neoplasms
1
2025
928
0.130
Why?
Tumor Cells, Cultured
5
2000
887
0.120
Why?
Glycosylation
4
2026
173
0.120
Why?
Trisomy
1
2017
78
0.120
Why?
Brain Chemistry
1
1996
120
0.120
Why?
Isoenzymes
1
1996
295
0.110
Why?
Proteins
1
2021
1023
0.110
Why?
Models, Biological
1
2003
1764
0.110
Why?
Endosomal Sorting Complexes Required for Transport
2
2025
46
0.110
Why?
Rats
8
2025
5585
0.110
Why?
Carcinoma, Hepatocellular
2
1997
373
0.110
Why?
Apoptosis
3
2025
2443
0.110
Why?
Cystic Fibrosis
1
2005
1163
0.110
Why?
Adult
8
2026
40872
0.100
Why?
Molecular Sequence Data
5
2015
2883
0.100
Why?
Brain
4
2023
2969
0.100
Why?
Disease Models, Animal
4
2025
4568
0.100
Why?
Mice
10
2025
18355
0.100
Why?
Oxidative Stress
2
2021
1359
0.100
Why?
Mitochondrial Proteins
1
2015
263
0.100
Why?
Membrane Proteins
3
2024
1166
0.090
Why?
Enzyme Induction
3
1997
88
0.090
Why?
Nerve Tissue Proteins
1
1996
592
0.090
Why?
Amino Acid Sequence
3
2015
2131
0.090
Why?
Transcription Factor AP-2
1
2011
82
0.090
Why?
Glioma
1
1995
429
0.080
Why?
Parkinson Disease
1
2017
601
0.080
Why?
Ethanol
1
2015
631
0.080
Why?
Mice, Inbred C57BL
4
2025
5992
0.080
Why?
Membrane Transport Proteins
1
2011
154
0.080
Why?
Adrenalectomy
4
1999
68
0.080
Why?
Cells, Cultured
4
2021
4151
0.080
Why?
Diabetes Mellitus, Type 1
1
2026
3937
0.070
Why?
Receptors, Nicotinic
1
2011
327
0.070
Why?
Attitude of Health Personnel
1
2017
1197
0.070
Why?
Diabetes Mellitus, Type 2
1
2023
2602
0.070
Why?
Palliative Care
1
2017
1022
0.070
Why?
Alcoholism
1
2015
826
0.070
Why?
Caregivers
1
2017
1074
0.070
Why?
DNA-Binding Proteins
2
2025
1482
0.070
Why?
Saccharomyces cerevisiae Proteins
1
2011
414
0.060
Why?
Schizophrenia
1
2011
464
0.060
Why?
Transcription Factors
2
2025
1736
0.060
Why?
Drug Stability
1
2007
169
0.060
Why?
Liver
1
1996
1899
0.060
Why?
DNA Primers
1
2007
505
0.060
Why?
Chemokine CXCL5
1
2026
19
0.060
Why?
Chemokine CXCL9
1
2026
38
0.060
Why?
Golgi Apparatus
2
2004
99
0.060
Why?
Polysaccharides
2
2004
86
0.060
Why?
Mutation
4
2017
4090
0.060
Why?
Protein Aggregates
1
2026
85
0.060
Why?
Ubiquitin Thiolesterase
1
2025
68
0.060
Why?
Middle Cerebral Artery
1
2025
56
0.060
Why?
Cytokines
2
2024
2069
0.060
Why?
Intercellular Signaling Peptides and Proteins
2
2024
376
0.060
Why?
Ultrasonography, Doppler, Transcranial
1
2025
48
0.060
Why?
DNA Methylation
2
2025
690
0.050
Why?
Case-Control Studies
2
2023
3634
0.050
Why?
Kinetics
2
1998
1568
0.050
Why?
Calnexin
1
2004
3
0.050
Why?
Centrifugation, Density Gradient
1
2004
36
0.050
Why?
Cycloheximide
1
2004
42
0.050
Why?
Concanavalin A
1
2004
72
0.050
Why?
Fluorescent Antibody Technique, Indirect
1
2004
45
0.050
Why?
Precipitin Tests
1
2004
90
0.050
Why?
Mass Spectrometry
1
2007
731
0.050
Why?
Cell Death
1
2025
382
0.050
Why?
Multienzyme Complexes
1
2004
65
0.050
Why?
Fluorescent Dyes
1
2025
334
0.050
Why?
Base Sequence
1
2007
2171
0.050
Why?
Virus Activation
1
2024
94
0.050
Why?
Protein Synthesis Inhibitors
1
2004
48
0.050
Why?
Cysteine Endopeptidases
1
2004
78
0.050
Why?
Glycolysis
1
2025
340
0.050
Why?
Intermediate Filaments
1
2023
25
0.050
Why?
Disulfides
1
2004
94
0.050
Why?
Time Factors
2
2025
7133
0.050
Why?
Sensory Receptor Cells
1
2024
98
0.050
Why?
Diet, High-Fat
1
2025
266
0.050
Why?
Sucrose
1
2004
114
0.050
Why?
Hippocampus
2
2022
973
0.050
Why?
Chemokines, CXC
1
2003
68
0.050
Why?
Fungal Proteins
1
2004
143
0.050
Why?
Carbohydrate Sequence
3
1999
29
0.050
Why?
Neurites
1
2023
50
0.050
Why?
Diffusion Tensor Imaging
1
2023
78
0.050
Why?
beta Catenin
1
2025
254
0.050
Why?
Plasmids
1
2004
373
0.050
Why?
Interferon-gamma
1
2026
784
0.050
Why?
Imipramine
1
2022
11
0.050
Why?
Cross-Sectional Studies
2
2026
5922
0.050
Why?
Growth Disorders
1
2022
89
0.050
Why?
Wnt Signaling Pathway
1
2024
212
0.050
Why?
Chemokines
1
2003
217
0.050
Why?
Gene Expression Regulation
1
2011
2601
0.050
Why?
Densitometry
1
2022
36
0.040
Why?
Retinal Ganglion Cells
1
2003
121
0.040
Why?
Hearing Loss, Sensorineural
1
2022
73
0.040
Why?
Diffusion Magnetic Resonance Imaging
1
2023
156
0.040
Why?
Transforming Growth Factor beta
1
2024
474
0.040
Why?
Virus Internalization
1
2022
65
0.040
Why?
Viral Proteins
1
2024
350
0.040
Why?
Polymerization
1
2022
127
0.040
Why?
Protein Structure, Tertiary
1
2004
855
0.040
Why?
Catalysis
1
2022
305
0.040
Why?
Cattle
1
2004
946
0.040
Why?
Oxidation-Reduction
1
2025
1068
0.040
Why?
Chromatin
1
2025
553
0.040
Why?
Lectins
2
1998
44
0.040
Why?
Mice, Knockout
2
2025
3130
0.040
Why?
Interneurons
1
2022
125
0.040
Why?
Receptors, HIV
1
2000
22
0.040
Why?
Tissue Plasminogen Activator
1
2023
248
0.040
Why?
Neuroimaging
1
2023
300
0.040
Why?
Immune System
1
2022
180
0.040
Why?
DNA, Complementary
1
2021
273
0.040
Why?
Insulin-Like Growth Factor I
1
2022
317
0.040
Why?
Retina
1
2003
329
0.040
Why?
Sensitivity and Specificity
1
2025
2000
0.040
Why?
Double-Blind Method
1
2025
2064
0.040
Why?
Teratocarcinoma
1
2000
2
0.040
Why?
Phagocytosis
1
2021
296
0.040
Why?
Receptors, Dopamine D2
1
2000
93
0.040
Why?
Intracellular Space
1
2020
64
0.040
Why?
Organoids
1
2021
144
0.040
Why?
Acyclovir
1
2020
98
0.040
Why?
Extracellular Space
1
2020
117
0.040
Why?
Pilot Projects
1
2025
1897
0.040
Why?
Phytohemagglutinins
1
1999
29
0.040
Why?
Viral Envelope Proteins
1
2020
98
0.040
Why?
Cell Line
2
2022
2823
0.040
Why?
Cerebral Palsy
1
2021
138
0.040
Why?
Thrombosis
1
2023
400
0.040
Why?
DNA, Viral
1
2021
356
0.040
Why?
Nicotine
1
2021
331
0.040
Why?
Genotype
1
2004
1857
0.040
Why?
Reactive Oxygen Species
1
2021
611
0.040
Why?
Induced Pluripotent Stem Cells
1
2021
273
0.030
Why?
Biomarkers, Tumor
1
2025
1329
0.030
Why?
Receptors, G-Protein-Coupled
1
2000
231
0.030
Why?
Gene Expression Regulation, Neoplastic
1
2024
1450
0.030
Why?
RNA, Messenger
2
2011
2805
0.030
Why?
MicroRNAs
1
2024
686
0.030
Why?
Asialoglycoproteins
1
1997
2
0.030
Why?
Fetuins
1
1997
3
0.030
Why?
Cytidine Monophosphate N-Acetylneuraminic Acid
1
1997
3
0.030
Why?
Calcium Signaling
1
2000
245
0.030
Why?
Nervous System
1
1998
69
0.030
Why?
Protein Binding
1
2004
2240
0.030
Why?
alpha-Fetoproteins
1
1997
42
0.030
Why?
Homozygote
1
2017
199
0.030
Why?
Gene Dosage
1
2017
145
0.030
Why?
Tretinoin
1
1998
125
0.030
Why?
Chromosomes, Human, Pair 21
1
2017
43
0.030
Why?
Heterozygote
1
2017
314
0.030
Why?
Carbohydrate Conformation
1
1996
15
0.030
Why?
Glycoproteins
1
1998
354
0.030
Why?
Oligosaccharides
1
1996
60
0.030
Why?
Parietal Lobe
1
1996
61
0.030
Why?
Glutathione Reductase
1
2015
24
0.030
Why?
Peroxiredoxins
1
2015
25
0.030
Why?
Substrate Specificity
1
1996
387
0.030
Why?
Brain Stem
1
1996
98
0.030
Why?
Glutathione Transferase
1
2015
92
0.030
Why?
Fetus
1
2000
804
0.030
Why?
Nervous System Diseases
1
1998
286
0.030
Why?
Adolescent
2
2025
22573
0.030
Why?
Acetylation
1
2015
259
0.030
Why?
Aldehydes
1
2015
140
0.030
Why?
Oxidative Phosphorylation
1
2015
209
0.030
Why?
Focus Groups
1
2017
572
0.030
Why?
Antiviral Agents
1
2020
769
0.030
Why?
Academic Medical Centers
1
2017
554
0.030
Why?
Cerebellum
1
1996
224
0.030
Why?
Glutathione
1
2015
370
0.020
Why?
Superoxide Dismutase
1
2015
308
0.020
Why?
Cell Differentiation
2
1998
2050
0.020
Why?
Risk Assessment
1
2023
3752
0.020
Why?
Interviews as Topic
1
2017
916
0.020
Why?
Mice, Transgenic
1
2017
2191
0.020
Why?
Neoplasm Proteins
1
1995
442
0.020
Why?
Lipid Metabolism
1
2015
529
0.020
Why?
SEC Translocation Channels
1
2011
9
0.020
Why?
Risk Factors
1
2026
10917
0.020
Why?
Amino Acids
1
2015
519
0.020
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2011
94
0.020
Why?
Lung
1
2024
4116
0.020
Why?
Mutagenesis, Site-Directed
1
2011
376
0.020
Why?
Protein Stability
1
2011
176
0.020
Why?
Hydrophobic and Hydrophilic Interactions
1
2011
192
0.020
Why?
Child, Preschool
1
2025
11868
0.020
Why?
Genetic Vectors
1
2011
335
0.020
Why?
HeLa Cells
1
2011
632
0.020
Why?
Protein Transport
1
2011
442
0.020
Why?
Qualitative Research
1
2017
1683
0.020
Why?
RNA, Small Interfering
1
2011
638
0.020
Why?
Young Adult
1
2025
14251
0.020
Why?
Treatment Outcome
1
2023
11793
0.020
Why?
Promoter Regions, Genetic
1
2011
1247
0.020
Why?
Antineoplastic Agents
1
1998
2219
0.020
Why?
Child
1
2025
22739
0.010
Why?
Transcription, Genetic
1
2011
1454
0.010
Why?
Retrospective Studies
1
2022
17325
0.010
Why?
In Situ Nick-End Labeling
1
2003
120
0.010
Why?
Chick Embryo
1
2003
132
0.010
Why?
Glycogen Synthase Kinase 3 beta
1
2003
74
0.010
Why?
Glycogen Synthase Kinase 3
1
2003
83
0.010
Why?
Chemokine CXCL12
1
2003
86
0.010
Why?
Nerve Growth Factors
1
2003
79
0.010
Why?
Receptors, CXCR4
1
2003
91
0.010
Why?
Infant
1
2017
10090
0.010
Why?
Cell Count
1
2003
319
0.010
Why?
Cyclic AMP
1
2003
208
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2003
125
0.010
Why?
Mitogen-Activated Protein Kinases
1
2003
288
0.010
Why?
Apelin Receptors
1
2000
4
0.010
Why?
Dopamine D2 Receptor Antagonists
1
2000
5
0.010
Why?
Apelin
1
2000
10
0.010
Why?
Adipokines
1
2000
57
0.010
Why?
Receptors, Virus
1
2000
95
0.010
Why?
Simian Immunodeficiency Virus
1
2000
93
0.010
Why?
Cell Survival
1
2003
1103
0.010
Why?
Primates
1
2000
133
0.010
Why?
Swainsonine
1
1999
1
0.010
Why?
1-Deoxynojirimycin
1
1999
1
0.010
Why?
Mannosidases
1
1999
3
0.010
Why?
Neuraminidase
1
1999
25
0.010
Why?
Tissue Distribution
1
1999
335
0.010
Why?
Phosphorylation
1
2003
1708
0.010
Why?
Transfection
1
2000
927
0.010
Why?
Biological Transport
1
1999
424
0.010
Why?
Leukocytes, Mononuclear
1
2000
574
0.010
Why?
Mice, Inbred BALB C
1
2000
1261
0.010
Why?
Solubility
1
1998
240
0.010
Why?
Blotting, Western
1
1999
1184
0.010
Why?
Pituitary Neoplasms
1
1999
190
0.010
Why?
Carrier Proteins
1
2000
729
0.010
Why?
HIV-1
1
2000
908
0.010
Why?
Antibodies, Monoclonal
1
2000
1505
0.010
Why?
T-Lymphocytes
1
2000
1997
0.010
Why?
Coughlan's Networks
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