Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christina Coughlan

Concepts (358)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Alzheimer Disease
10
2025
606
2.200
Why?
Extracellular Vesicles
9
2025
162
2.100
Why?
Exosomes
3
2023
108
0.810
Why?
Astrocytes
4
2022
219
0.790
Why?
White Matter
2
2023
146
0.760
Why?
Gliosis
2
2023
29
0.730
Why?
Proteasome Endopeptidase Complex
2
2022
160
0.720
Why?
Glial Fibrillary Acidic Protein
2
2025
112
0.710
Why?
Sialyltransferases
8
1999
13
0.710
Why?
Amyloid beta-Protein Precursor
5
2022
67
0.670
Why?
Healthy Aging
1
2021
37
0.660
Why?
Ultracentrifugation
1
2020
51
0.660
Why?
Memory, Episodic
1
2021
53
0.650
Why?
Neurons
8
2026
1636
0.570
Why?
Saccharomyces cerevisiae
5
2022
556
0.550
Why?
Proteomics
4
2026
1161
0.510
Why?
Amyloid beta-Peptides
5
2022
235
0.500
Why?
Peptide Fragments
3
2022
698
0.470
Why?
Cognitive Dysfunction
3
2025
441
0.420
Why?
Nanoparticles
1
2020
504
0.420
Why?
Dexamethasone
7
1999
378
0.390
Why?
Brain Ischemia
2
2025
351
0.330
Why?
Islet Amyloid Polypeptide
2
2021
48
0.320
Why?
Herpes Zoster
3
2024
319
0.320
Why?
Down Syndrome
4
2022
514
0.320
Why?
Sialoglycoproteins
3
1997
160
0.280
Why?
Protein Folding
3
2005
277
0.270
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
2
2025
153
0.270
Why?
Oligoclonal Bands
1
2026
25
0.240
Why?
Neuroblastoma
3
1999
165
0.240
Why?
Herpesvirus 3, Human
3
2024
336
0.240
Why?
Proteome
2
2024
494
0.230
Why?
Stroke
3
2023
1213
0.230
Why?
Plasma
2
2024
222
0.230
Why?
Sodium Bicarbonate
1
2025
46
0.230
Why?
Biomarkers
8
2025
4241
0.220
Why?
Tetraspanin 28
1
2024
6
0.220
Why?
Protein Conformation
2
2005
942
0.220
Why?
Intra-Abdominal Fat
1
2025
98
0.220
Why?
Chordoma
1
2024
17
0.220
Why?
DNA Transposable Elements
1
2025
121
0.220
Why?
Humans
39
2026
143560
0.220
Why?
Idiopathic Pulmonary Fibrosis
2
2024
674
0.210
Why?
alpha-Synuclein
1
2024
44
0.210
Why?
Acidosis
1
2025
105
0.210
Why?
Fluorescence Resonance Energy Transfer
1
2025
177
0.210
Why?
Amyloidogenic Proteins
1
2024
16
0.210
Why?
Aprotinin
1
2004
9
0.210
Why?
Varicella Zoster Virus Infection
2
2024
24
0.210
Why?
Mitochondria
2
2025
988
0.210
Why?
Aged, 80 and over
8
2025
8072
0.210
Why?
Vacuoles
1
2004
39
0.210
Why?
Osteoblasts
1
2024
143
0.210
Why?
Glucocorticoids
3
1999
537
0.210
Why?
Central Nervous System
1
2026
269
0.210
Why?
Interleukin-6
2
2025
781
0.210
Why?
Recombinant Proteins
2
2007
1369
0.200
Why?
Carcinogenesis
1
2025
232
0.200
Why?
Animals
24
2025
38010
0.200
Why?
Tumor Microenvironment
2
2024
732
0.200
Why?
Neurodegenerative Diseases
1
2005
143
0.200
Why?
Bleomycin
1
2024
242
0.190
Why?
Cerebrovascular Circulation
1
2025
272
0.190
Why?
Epithelial-Mesenchymal Transition
1
2024
219
0.190
Why?
Diabetic Neuropathies
1
2023
97
0.190
Why?
Colon
1
2025
306
0.190
Why?
Apolipoprotein E4
1
2022
38
0.180
Why?
Ischemic Attack, Transient
1
2023
71
0.180
Why?
Disease
1
2003
99
0.180
Why?
Protein Processing, Post-Translational
4
2011
474
0.180
Why?
Obesity
2
2025
3041
0.180
Why?
Fatty Acids
1
2025
452
0.180
Why?
Cognition
3
2025
1261
0.180
Why?
Carcinoma, Pancreatic Ductal
1
2025
308
0.180
Why?
Bronchoalveolar Lavage Fluid
1
2024
639
0.180
Why?
Immunoglobulin G
1
2026
898
0.180
Why?
Endoplasmic Reticulum
1
2004
263
0.180
Why?
Retinal Drusen
1
2021
31
0.170
Why?
Peptides
2
2024
976
0.170
Why?
Virion
1
2022
114
0.170
Why?
Retinal Pigment Epithelium
1
2021
81
0.170
Why?
Aldosterone
4
1999
43
0.170
Why?
Arteritis
1
2021
25
0.170
Why?
Central Nervous System Viral Diseases
1
2022
79
0.170
Why?
Chemical Precipitation
1
2020
39
0.170
Why?
Cell Polarity
1
2021
140
0.160
Why?
Brain-Derived Neurotrophic Factor
1
2021
142
0.160
Why?
Myelitis
1
2022
106
0.160
Why?
Stem Cells
1
2025
619
0.160
Why?
Aged
12
2025
25322
0.160
Why?
Adipose Tissue
1
2025
654
0.160
Why?
Enterovirus D, Human
1
2022
87
0.160
Why?
Epigenesis, Genetic
1
2025
686
0.160
Why?
Amyloid
1
2021
96
0.160
Why?
Multiple Sclerosis
1
2026
483
0.160
Why?
Receptors, Chemokine
1
2000
48
0.160
Why?
Cell Movement
1
2024
973
0.160
Why?
Neuromuscular Diseases
1
2022
146
0.160
Why?
Chemokine CCL2
1
2000
115
0.150
Why?
Macular Degeneration
1
2021
189
0.150
Why?
Adrenal Cortex Hormones
3
1999
505
0.150
Why?
Enterovirus Infections
1
2022
174
0.150
Why?
Wnt-5a Protein
1
2018
25
0.150
Why?
Renal Insufficiency, Chronic
1
2025
637
0.150
Why?
Fibroblasts
1
2024
1044
0.140
Why?
Signal Transduction
4
2021
5214
0.140
Why?
Apoptosis
4
2026
2519
0.140
Why?
Cell Line, Tumor
5
2025
3611
0.140
Why?
Aging
3
2025
1946
0.140
Why?
Frontotemporal Lobar Degeneration
1
2017
19
0.140
Why?
Cell Communication
2
2000
313
0.130
Why?
Middle Aged
11
2026
35342
0.130
Why?
N-Acetylneuraminic Acid
2
1999
14
0.130
Why?
Kidney
2
2015
1507
0.130
Why?
Colorectal Neoplasms
1
2025
833
0.130
Why?
Proteostasis Deficiencies
1
2017
5
0.130
Why?
Aneuploidy
1
2017
89
0.130
Why?
Melanoma
1
2024
807
0.130
Why?
Pancreatic Neoplasms
1
2025
924
0.130
Why?
Male
16
2026
71500
0.130
Why?
tau Proteins
1
2017
98
0.130
Why?
Tumor Cells, Cultured
5
2000
974
0.130
Why?
Glycosylation
4
2026
173
0.120
Why?
Trisomy
1
2017
78
0.120
Why?
Brain Chemistry
1
1996
115
0.120
Why?
Female
15
2026
77251
0.120
Why?
Proteins
1
2021
1022
0.120
Why?
Isoenzymes
1
1996
299
0.110
Why?
Endosomal Sorting Complexes Required for Transport
2
2025
43
0.110
Why?
Carcinoma, Hepatocellular
2
1997
365
0.110
Why?
Rats
8
2025
5610
0.110
Why?
Cystic Fibrosis
1
2005
1142
0.110
Why?
Models, Biological
1
2003
1831
0.110
Why?
Neurofilament Proteins
2
2025
62
0.110
Why?
Molecular Sequence Data
5
2015
2942
0.100
Why?
Brain
4
2023
2892
0.100
Why?
Disease Models, Animal
4
2025
4522
0.100
Why?
Mice
10
2025
18378
0.100
Why?
Oxidative Stress
2
2021
1370
0.100
Why?
Mitochondrial Proteins
1
2015
262
0.100
Why?
Membrane Proteins
3
2024
1171
0.090
Why?
Enzyme Induction
3
1997
89
0.090
Why?
Nerve Tissue Proteins
1
1996
607
0.090
Why?
Amino Acid Sequence
3
2015
2165
0.090
Why?
Transcription Factor AP-2
1
2011
82
0.090
Why?
Glioma
1
1995
425
0.080
Why?
Parkinson Disease
1
2017
576
0.080
Why?
Adult
6
2026
40013
0.080
Why?
Ethanol
1
2015
639
0.080
Why?
Mice, Inbred C57BL
4
2025
6043
0.080
Why?
Adrenalectomy
4
1999
70
0.080
Why?
Membrane Transport Proteins
1
2011
156
0.080
Why?
Cells, Cultured
4
2021
4182
0.080
Why?
Palliative Care
1
2017
852
0.080
Why?
Receptors, Nicotinic
1
2011
344
0.070
Why?
Diabetes Mellitus, Type 2
1
2023
2575
0.070
Why?
Attitude of Health Personnel
1
2017
1207
0.070
Why?
Caregivers
1
2017
970
0.070
Why?
Alcoholism
1
2015
838
0.070
Why?
DNA-Binding Proteins
2
2025
1524
0.070
Why?
Schizophrenia
1
2011
442
0.070
Why?
Saccharomyces cerevisiae Proteins
1
2011
403
0.070
Why?
Liver
1
1996
1864
0.060
Why?
Drug Stability
1
2007
165
0.060
Why?
Transcription Factors
2
2025
1754
0.060
Why?
DNA Primers
1
2007
518
0.060
Why?
Golgi Apparatus
2
2004
100
0.060
Why?
Polysaccharides
2
2004
88
0.060
Why?
Mutation
4
2017
4053
0.060
Why?
Ubiquitin Thiolesterase
1
2025
61
0.060
Why?
Middle Cerebral Artery
1
2025
55
0.060
Why?
Protein Aggregates
1
2026
83
0.060
Why?
Ultrasonography, Doppler, Transcranial
1
2025
45
0.060
Why?
Intercellular Signaling Peptides and Proteins
2
2024
389
0.060
Why?
Cytokines
2
2024
2097
0.060
Why?
DNA Methylation
2
2025
667
0.060
Why?
Case-Control Studies
2
2023
3625
0.050
Why?
Calnexin
1
2004
3
0.050
Why?
Centrifugation, Density Gradient
1
2004
39
0.050
Why?
Cycloheximide
1
2004
49
0.050
Why?
Concanavalin A
1
2004
72
0.050
Why?
Fluorescent Antibody Technique, Indirect
1
2004
47
0.050
Why?
Kinetics
2
1998
1628
0.050
Why?
Precipitin Tests
1
2004
97
0.050
Why?
Mass Spectrometry
1
2007
740
0.050
Why?
Cell Death
1
2025
394
0.050
Why?
Virus Activation
1
2024
86
0.050
Why?
Fluorescent Dyes
1
2025
325
0.050
Why?
Multienzyme Complexes
1
2004
66
0.050
Why?
Cysteine Endopeptidases
1
2004
74
0.050
Why?
Protein Synthesis Inhibitors
1
2004
46
0.050
Why?
Base Sequence
1
2007
2199
0.050
Why?
Intermediate Filaments
1
2023
26
0.050
Why?
Glycolysis
1
2025
335
0.050
Why?
Disulfides
1
2004
99
0.050
Why?
Time Factors
2
2025
7031
0.050
Why?
Hippocampus
2
2022
948
0.050
Why?
Sucrose
1
2004
111
0.050
Why?
Diet, High-Fat
1
2025
260
0.050
Why?
Sensory Receptor Cells
1
2024
101
0.050
Why?
Fungal Proteins
1
2004
141
0.050
Why?
Chemokines, CXC
1
2003
70
0.050
Why?
Carbohydrate Sequence
3
1999
29
0.050
Why?
Neurites
1
2023
52
0.050
Why?
Diffusion Tensor Imaging
1
2023
75
0.050
Why?
beta Catenin
1
2025
256
0.050
Why?
Plasmids
1
2004
371
0.050
Why?
Imipramine
1
2022
11
0.050
Why?
Growth Disorders
1
2022
87
0.050
Why?
Inflammation
2
2025
2881
0.050
Why?
Wnt Signaling Pathway
1
2024
213
0.050
Why?
Hearing Loss, Sensorineural
1
2022
69
0.050
Why?
Chemokines
1
2003
223
0.050
Why?
Densitometry
1
2022
38
0.050
Why?
Retinal Ganglion Cells
1
2003
120
0.050
Why?
Gene Expression Regulation
1
2011
2621
0.050
Why?
Diffusion Magnetic Resonance Imaging
1
2023
156
0.050
Why?
Virus Internalization
1
2022
64
0.040
Why?
Transforming Growth Factor beta
1
2024
484
0.040
Why?
Polymerization
1
2022
128
0.040
Why?
Viral Proteins
1
2024
370
0.040
Why?
Protein Structure, Tertiary
1
2004
863
0.040
Why?
Catalysis
1
2022
322
0.040
Why?
Cattle
1
2004
990
0.040
Why?
Chromatin
1
2025
554
0.040
Why?
Lectins
2
1998
43
0.040
Why?
Oxidation-Reduction
1
2025
1091
0.040
Why?
Mice, Knockout
2
2025
3109
0.040
Why?
Interneurons
1
2022
124
0.040
Why?
Receptors, HIV
1
2000
25
0.040
Why?
Tissue Plasminogen Activator
1
2023
239
0.040
Why?
Neuroimaging
1
2023
282
0.040
Why?
DNA, Complementary
1
2021
277
0.040
Why?
Immune System
1
2022
183
0.040
Why?
Insulin-Like Growth Factor I
1
2022
318
0.040
Why?
Sensitivity and Specificity
1
2025
1984
0.040
Why?
Double-Blind Method
1
2025
2017
0.040
Why?
Retina
1
2003
324
0.040
Why?
Teratocarcinoma
1
2000
2
0.040
Why?
Organoids
1
2021
133
0.040
Why?
Phagocytosis
1
2021
291
0.040
Why?
Receptors, Dopamine D2
1
2000
96
0.040
Why?
Intracellular Space
1
2020
67
0.040
Why?
Acyclovir
1
2020
96
0.040
Why?
Pilot Projects
1
2025
1838
0.040
Why?
Extracellular Space
1
2020
129
0.040
Why?
Phytohemagglutinins
1
1999
29
0.040
Why?
Viral Envelope Proteins
1
2020
98
0.040
Why?
Cerebral Palsy
1
2021
129
0.040
Why?
Cell Line
2
2022
2897
0.040
Why?
DNA, Viral
1
2021
366
0.040
Why?
Thrombosis
1
2023
401
0.040
Why?
Nicotine
1
2021
342
0.040
Why?
Genotype
1
2004
1877
0.040
Why?
Receptors, G-Protein-Coupled
1
2000
219
0.040
Why?
Reactive Oxygen Species
1
2021
642
0.040
Why?
Biomarkers, Tumor
1
2025
1282
0.040
Why?
Induced Pluripotent Stem Cells
1
2021
272
0.040
Why?
RNA, Messenger
2
2011
2852
0.030
Why?
Gene Expression Regulation, Neoplastic
1
2024
1487
0.030
Why?
Fetuins
1
1997
2
0.030
Why?
Asialoglycoproteins
1
1997
2
0.030
Why?
Cytidine Monophosphate N-Acetylneuraminic Acid
1
1997
3
0.030
Why?
Calcium Signaling
1
2000
248
0.030
Why?
MicroRNAs
1
2024
698
0.030
Why?
Nervous System
1
1998
70
0.030
Why?
Protein Binding
1
2004
2261
0.030
Why?
alpha-Fetoproteins
1
1997
40
0.030
Why?
Homozygote
1
2017
201
0.030
Why?
Gene Dosage
1
2017
149
0.030
Why?
Tretinoin
1
1998
124
0.030
Why?
Chromosomes, Human, Pair 21
1
2017
42
0.030
Why?
Heterozygote
1
2017
311
0.030
Why?
Carbohydrate Conformation
1
1996
15
0.030
Why?
Glycoproteins
1
1998
356
0.030
Why?
Oligosaccharides
1
1996
60
0.030
Why?
Parietal Lobe
1
1996
59
0.030
Why?
Glutathione Reductase
1
2015
25
0.030
Why?
Peroxiredoxins
1
2015
26
0.030
Why?
Substrate Specificity
1
1996
383
0.030
Why?
Brain Stem
1
1996
96
0.030
Why?
Glutathione Transferase
1
2015
99
0.030
Why?
Fetus
1
2000
806
0.030
Why?
Nervous System Diseases
1
1998
280
0.030
Why?
Adolescent
2
2025
22481
0.030
Why?
Acetylation
1
2015
249
0.030
Why?
Aldehydes
1
2015
146
0.030
Why?
Oxidative Phosphorylation
1
2015
209
0.030
Why?
Focus Groups
1
2017
570
0.030
Why?
Academic Medical Centers
1
2017
535
0.030
Why?
Antiviral Agents
1
2020
764
0.030
Why?
Cerebellum
1
1996
222
0.030
Why?
Risk Assessment
1
2023
3577
0.020
Why?
Glutathione
1
2015
373
0.020
Why?
Interviews as Topic
1
2017
868
0.020
Why?
Cell Differentiation
2
1998
2020
0.020
Why?
Superoxide Dismutase
1
2015
346
0.020
Why?
Mice, Transgenic
1
2017
2194
0.020
Why?
Neoplasm Proteins
1
1995
443
0.020
Why?
Lipid Metabolism
1
2015
524
0.020
Why?
SEC Translocation Channels
1
2011
10
0.020
Why?
Amino Acids
1
2015
511
0.020
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2011
97
0.020
Why?
Lung
1
2024
4101
0.020
Why?
Protein Stability
1
2011
175
0.020
Why?
Mutagenesis, Site-Directed
1
2011
382
0.020
Why?
Hydrophobic and Hydrophilic Interactions
1
2011
190
0.020
Why?
Child, Preschool
1
2025
11737
0.020
Why?
Genetic Vectors
1
2011
342
0.020
Why?
Cross-Sectional Studies
1
2021
5743
0.020
Why?
HeLa Cells
1
2011
650
0.020
Why?
Protein Transport
1
2011
447
0.020
Why?
Qualitative Research
1
2017
1563
0.020
Why?
RNA, Small Interfering
1
2011
637
0.020
Why?
Young Adult
1
2025
13972
0.020
Why?
Treatment Outcome
1
2023
11365
0.020
Why?
Promoter Regions, Genetic
1
2011
1263
0.020
Why?
Antineoplastic Agents
1
1998
2195
0.020
Why?
Child
1
2025
22725
0.010
Why?
Transcription, Genetic
1
2011
1511
0.010
Why?
Retrospective Studies
1
2022
16741
0.010
Why?
In Situ Nick-End Labeling
1
2003
129
0.010
Why?
Chick Embryo
1
2003
136
0.010
Why?
Glycogen Synthase Kinase 3 beta
1
2003
74
0.010
Why?
Glycogen Synthase Kinase 3
1
2003
82
0.010
Why?
Chemokine CXCL12
1
2003
89
0.010
Why?
Nerve Growth Factors
1
2003
79
0.010
Why?
Receptors, CXCR4
1
2003
91
0.010
Why?
Infant
1
2017
9981
0.010
Why?
Cell Count
1
2003
323
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2003
128
0.010
Why?
Cyclic AMP
1
2003
215
0.010
Why?
Mitogen-Activated Protein Kinases
1
2003
302
0.010
Why?
Dopamine D2 Receptor Antagonists
1
2000
4
0.010
Why?
Apelin Receptors
1
2000
4
0.010
Why?
Apelin
1
2000
10
0.010
Why?
Adipokines
1
2000
53
0.010
Why?
Receptors, Virus
1
2000
95
0.010
Why?
Simian Immunodeficiency Virus
1
2000
92
0.010
Why?
Cell Survival
1
2003
1136
0.010
Why?
Primates
1
2000
133
0.010
Why?
Swainsonine
1
1999
1
0.010
Why?
1-Deoxynojirimycin
1
1999
1
0.010
Why?
Mannosidases
1
1999
4
0.010
Why?
Neuraminidase
1
1999
25
0.010
Why?
Tissue Distribution
1
1999
330
0.010
Why?
Phosphorylation
1
2003
1781
0.010
Why?
Transfection
1
2000
949
0.010
Why?
Biological Transport
1
1999
412
0.010
Why?
Mice, Inbred BALB C
1
2000
1272
0.010
Why?
Leukocytes, Mononuclear
1
2000
589
0.010
Why?
Solubility
1
1998
239
0.010
Why?
Blotting, Western
1
1999
1223
0.010
Why?
Pituitary Neoplasms
1
1999
195
0.010
Why?
Carrier Proteins
1
2000
752
0.010
Why?
HIV-1
1
2000
892
0.010
Why?
Antibodies, Monoclonal
1
2000
1474
0.010
Why?
T-Lymphocytes
1
2000
2026
0.010
Why?
Coughlan's Networks
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