Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Kenneth Malcolm

Concepts (312)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Mycobacterium abscessus
11
2025
118
3.930
Why?
Mycobacterium Infections, Nontuberculous
16
2025
368
3.030
Why?
Neutrophils
30
2025
1118
2.670
Why?
Host-Pathogen Interactions
4
2025
369
1.710
Why?
Cystic Fibrosis
16
2025
1166
1.600
Why?
Phagocytosis
8
2026
296
1.090
Why?
Azithromycin
4
2020
105
0.830
Why?
Immunity, Humoral
1
2025
120
0.820
Why?
Interferons
2
2016
185
0.750
Why?
Lipopolysaccharides
11
2025
854
0.740
Why?
Gene Expression Regulation
7
2020
2591
0.680
Why?
Immunity, Innate
3
2025
843
0.620
Why?
Klebsiella pneumoniae
2
2018
47
0.590
Why?
Pseudomonas
1
2018
33
0.570
Why?
Pseudomonas aeruginosa
8
2022
391
0.540
Why?
Fomites
1
2017
7
0.530
Why?
Cytotoxicity, Immunologic
1
2018
221
0.520
Why?
Nontuberculous Mycobacteria
7
2025
210
0.510
Why?
Anti-Bacterial Agents
11
2024
1928
0.490
Why?
Mitogen-Activated Protein Kinases
7
2004
287
0.400
Why?
Pseudomonas Infections
5
2022
230
0.380
Why?
Myelodysplastic Syndromes
2
2026
147
0.380
Why?
Neutrophil Activation
1
2013
84
0.370
Why?
Mycobacterium Infections
1
2013
61
0.370
Why?
Reactive Oxygen Species
4
2020
601
0.370
Why?
Staphylococcus aureus
3
2015
454
0.350
Why?
Mycobacterium
1
2013
116
0.340
Why?
Superoxides
5
2018
199
0.340
Why?
Bacteria
1
2018
894
0.330
Why?
Sputum
5
2025
308
0.320
Why?
Microbial Viability
3
2018
91
0.300
Why?
Immunoglobulin G
2
2025
886
0.300
Why?
Biofilms
5
2014
301
0.270
Why?
Extracellular Traps
2
2018
51
0.260
Why?
Immunoglobulin M
2
2025
281
0.240
Why?
Interleukin-8
3
2020
269
0.240
Why?
Humans
46
2026
144667
0.240
Why?
Macrophages
5
2026
1496
0.220
Why?
Mannose-Binding Lectin
1
2025
20
0.220
Why?
Phage Therapy
1
2025
17
0.220
Why?
Gene Expression Profiling
3
2018
1766
0.220
Why?
Extracellular Space
2
2018
119
0.220
Why?
Cell Separation
3
2016
303
0.210
Why?
Oligonucleotide Array Sequence Analysis
3
2002
751
0.210
Why?
Antibodies, Bacterial
1
2025
146
0.210
Why?
Complement C3
1
2025
192
0.200
Why?
Tobramycin
4
2016
59
0.190
Why?
Toll-Like Receptors
3
2017
193
0.190
Why?
Cytokines
8
2018
2045
0.180
Why?
GTP-Binding Proteins
1
2003
153
0.180
Why?
Antimalarials
1
2022
35
0.180
Why?
p38 Mitogen-Activated Protein Kinases
7
2011
265
0.180
Why?
Primary Cell Culture
2
2020
172
0.180
Why?
Complement Activation
1
2025
409
0.170
Why?
Disease Models, Animal
6
2026
4539
0.170
Why?
Case-Control Studies
3
2020
3603
0.170
Why?
Pneumonia, Bacterial
3
2013
113
0.170
Why?
Chemokine CCL4
1
2020
31
0.160
Why?
Bacteriophages
1
2022
111
0.160
Why?
Chloroquine
1
2020
53
0.160
Why?
RNA Splicing
2
2023
286
0.160
Why?
Mycobacterium tuberculosis
1
2022
337
0.140
Why?
Sirolimus
1
2020
280
0.140
Why?
Intracellular Space
1
2018
64
0.130
Why?
Autophagy
1
2020
284
0.130
Why?
Mice
15
2026
18261
0.130
Why?
Respiratory System
1
2018
151
0.130
Why?
Adaptor Proteins, Signal Transducing
1
2020
426
0.130
Why?
Lung
9
2024
4089
0.130
Why?
Aztreonam
1
2016
11
0.130
Why?
Antiviral Agents
1
2003
765
0.120
Why?
Leukemia, Myeloid, Acute
1
2023
685
0.120
Why?
Signal Transduction
3
2020
5185
0.120
Why?
C-Reactive Protein
1
2018
420
0.120
Why?
Survival Analysis
2
2016
1370
0.110
Why?
Immunosuppressive Agents
1
2020
834
0.110
Why?
Interferon-alpha
1
2016
194
0.110
Why?
Alternative Splicing
1
2017
247
0.110
Why?
Microbial Sensitivity Tests
4
2022
373
0.110
Why?
Antimicrobial Cationic Peptides
1
2015
81
0.110
Why?
Severity of Illness Index
4
2018
2922
0.110
Why?
Granulomatous Disease, Chronic
1
2014
48
0.110
Why?
Leukocytes, Mononuclear
1
2017
572
0.110
Why?
Cell Movement
4
2013
959
0.110
Why?
Metalloproteases
1
2014
42
0.110
Why?
Oxidants
1
2014
103
0.110
Why?
RNA, Messenger
3
2022
2815
0.100
Why?
Phagocytes
1
2014
79
0.100
Why?
Deoxyribonucleases
2
2011
24
0.100
Why?
Thiazolidinediones
1
2014
139
0.100
Why?
Kaplan-Meier Estimate
1
2016
967
0.100
Why?
Quorum Sensing
1
2014
80
0.100
Why?
Odds Ratio
1
2016
1076
0.100
Why?
Tumor Necrosis Factor-alpha
5
2011
1207
0.100
Why?
Animals
16
2026
37948
0.100
Why?
Cell Death
2
2013
382
0.100
Why?
Male
14
2026
72431
0.090
Why?
Rhinitis
1
2015
169
0.090
Why?
Virulence Factors
1
2014
177
0.090
Why?
Multivariate Analysis
1
2016
1537
0.090
Why?
Prospective Studies
5
2025
7994
0.090
Why?
Wound Infection
1
2013
59
0.090
Why?
Sinusitis
1
2015
227
0.090
Why?
Cellular Structures
1
2011
6
0.090
Why?
Lipid Metabolism
1
2015
524
0.090
Why?
Contact Lenses, Hydrophilic
1
2011
7
0.090
Why?
Myocytes, Smooth Muscle
1
2013
264
0.090
Why?
Neutrophil Infiltration
3
2013
104
0.080
Why?
Actins
3
2009
421
0.080
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
1
2013
294
0.080
Why?
Chemokine CXCL5
1
2011
19
0.080
Why?
Cell Lineage
1
2013
376
0.080
Why?
Female
13
2026
78304
0.080
Why?
Eye Infections, Bacterial
1
2011
45
0.080
Why?
Treatment Outcome
4
2025
11735
0.080
Why?
Interleukin-17
1
2011
118
0.080
Why?
Biomarkers
4
2025
4261
0.080
Why?
Lipids
1
2015
706
0.080
Why?
Species Specificity
1
2011
573
0.080
Why?
Viruses
1
2011
166
0.070
Why?
Tumor Suppressor Protein p53
1
2013
532
0.070
Why?
Retroviridae
1
2008
101
0.070
Why?
cdc42 GTP-Binding Protein
2
2006
21
0.070
Why?
Pulmonary Alveoli
1
2011
383
0.070
Why?
Peptides
2
2011
989
0.070
Why?
Transgenes
1
2008
191
0.070
Why?
Mitochondria
1
2014
984
0.070
Why?
Burns
1
2013
371
0.070
Why?
Kruppel-Like Transcription Factors
1
2008
77
0.060
Why?
Pulmonary Artery
1
2013
1124
0.060
Why?
Adult
8
2025
40489
0.060
Why?
Bone Marrow
1
2008
306
0.060
Why?
Adaptor Proteins, Vesicular Transport
1
2007
45
0.060
Why?
Endothelium, Vascular
1
2013
949
0.060
Why?
Membrane Glycoproteins
2
2014
496
0.060
Why?
rhoA GTP-Binding Protein
1
2006
76
0.060
Why?
Escherichia coli Infections
1
2007
126
0.060
Why?
Up-Regulation
3
2006
848
0.060
Why?
Cohort Studies
2
2020
5957
0.060
Why?
Cell Culture Techniques
1
2008
372
0.060
Why?
Middle Aged
4
2020
35971
0.060
Why?
Inflammation
5
2022
2870
0.060
Why?
Hydroxyeicosatetraenoic Acids
1
2005
35
0.060
Why?
Respiratory Mucosa
1
2008
322
0.060
Why?
MAP Kinase Signaling System
1
2007
306
0.050
Why?
Toll-Like Receptor 4
2
2007
277
0.050
Why?
Dinoprostone
1
2005
180
0.050
Why?
DNA
2
2009
1447
0.050
Why?
Drug Therapy, Combination
3
2013
1044
0.050
Why?
Membrane Microdomains
1
2004
34
0.050
Why?
Inflammation Mediators
2
2011
503
0.050
Why?
Transcription, Genetic
4
2008
1468
0.050
Why?
beta-Cyclodextrins
1
2004
32
0.050
Why?
NF-kappa B
4
2013
657
0.050
Why?
Enzyme Precursors
1
2003
15
0.050
Why?
Chemokines, CXC
1
2004
68
0.050
Why?
Receptors, CXCR4
1
2004
91
0.050
Why?
Mutation
2
2026
4081
0.050
Why?
Zymosan
1
2023
39
0.050
Why?
Splicing Factor U2AF
1
2023
18
0.050
Why?
Multicenter Studies as Topic
1
2025
408
0.050
Why?
Drug Evaluation, Preclinical
1
2024
195
0.050
Why?
Myxovirus Resistance Proteins
1
2003
13
0.050
Why?
Mycobacterium avium
1
2023
21
0.050
Why?
Bacterial Load
2
2015
67
0.050
Why?
eIF-2 Kinase
1
2003
29
0.050
Why?
Young Adult
3
2020
14122
0.050
Why?
Chemotaxis
1
2023
123
0.050
Why?
STAT1 Transcription Factor
1
2003
66
0.050
Why?
Enzyme Activation
4
2008
762
0.050
Why?
Anti-Inflammatory Agents, Non-Steroidal
2
2002
338
0.050
Why?
Phosphoprotein Phosphatases
1
2002
65
0.050
Why?
Escherichia coli
1
2007
854
0.050
Why?
Macrophages, Alveolar
1
2005
368
0.050
Why?
Cell Differentiation
2
2026
2037
0.040
Why?
Toll-Like Receptor 2
1
2003
127
0.040
Why?
Risk Factors
1
2016
10796
0.040
Why?
Interferon Type I
1
2003
146
0.040
Why?
Gene Expression
2
2008
1476
0.040
Why?
Phosphatidylinositol 3-Kinases
1
2003
380
0.040
Why?
STAT3 Transcription Factor
1
2003
205
0.040
Why?
Transcriptional Activation
2
2013
372
0.040
Why?
Ciprofloxacin
2
2013
31
0.040
Why?
Gene Expression Regulation, Enzymologic
1
2002
268
0.040
Why?
Receptors, Cell Surface
1
2003
370
0.040
Why?
Apoptosis
2
2008
2397
0.040
Why?
Administration, Inhalation
1
2022
570
0.040
Why?
Protein-Tyrosine Kinases
1
2003
431
0.040
Why?
Trans-Activators
1
2003
397
0.040
Why?
Glycolipids
1
2020
52
0.040
Why?
Clinical Trials as Topic
1
2025
1056
0.040
Why?
Mice, Knockout
3
2014
3109
0.040
Why?
Complement System Proteins
1
2023
314
0.040
Why?
Transforming Growth Factor beta
1
2002
475
0.040
Why?
Aged, 80 and over
1
2011
8284
0.040
Why?
Time Factors
3
2018
7140
0.040
Why?
British Columbia
1
2018
23
0.030
Why?
Bronchoalveolar Lavage Fluid
2
2015
630
0.030
Why?
Mice, Transgenic
1
2023
2184
0.030
Why?
Chemokine CXCL1
2
2011
76
0.030
Why?
Cell Migration Inhibition
2
2011
16
0.030
Why?
Chemotaxis, Leukocyte
2
2011
113
0.030
Why?
Morbidity
1
2018
322
0.030
Why?
Drug Administration Routes
1
2016
42
0.030
Why?
Imidazoles
3
2002
246
0.030
Why?
RNA Precursors
1
2017
154
0.030
Why?
Mice, Inbred C57BL
4
2011
5967
0.030
Why?
Proteins
1
2002
1016
0.030
Why?
DNA-Binding Proteins
1
2003
1484
0.030
Why?
Cathelicidins
1
2015
41
0.030
Why?
Drug Interactions
1
2016
401
0.030
Why?
Aged
2
2015
25955
0.030
Why?
NADPH Oxidase 2
1
2014
32
0.030
Why?
Respiratory Function Tests
1
2016
541
0.030
Why?
Predictive Value of Tests
1
2020
2117
0.030
Why?
Gentamicins
1
2015
50
0.030
Why?
Chronic Disease
2
2015
1810
0.030
Why?
Enzyme Inhibitors
3
2002
820
0.030
Why?
Reproducibility of Results
1
2002
3414
0.030
Why?
Pilot Projects
1
2020
1886
0.030
Why?
NADPH Oxidases
1
2014
120
0.030
Why?
Drug Resistance, Multiple, Bacterial
1
2014
81
0.030
Why?
Recombinant Proteins
2
2011
1363
0.030
Why?
Drug Resistance, Bacterial
1
2015
205
0.020
Why?
PPAR gamma
1
2014
177
0.020
Why?
Asthma
1
2005
1774
0.020
Why?
Drug Monitoring
1
2016
396
0.020
Why?
Survival Rate
1
2018
2089
0.020
Why?
JNK Mitogen-Activated Protein Kinases
2
2003
153
0.020
Why?
Spleen
1
2015
510
0.020
Why?
Chemokine CCL2
2
2003
112
0.020
Why?
Leukocyte Count
1
2013
315
0.020
Why?
Adenoviridae
1
2013
199
0.020
Why?
Cell Hypoxia
1
2013
248
0.020
Why?
Gene Knockdown Techniques
1
2013
334
0.020
Why?
Fibrinogen
1
2013
181
0.020
Why?
Down-Regulation
2
2006
616
0.020
Why?
Drug Synergism
1
2013
352
0.020
Why?
Neovascularization, Physiologic
1
2013
191
0.020
Why?
Monocytes
1
2014
536
0.020
Why?
Suspensions
1
2011
28
0.020
Why?
Gene Deletion
1
2013
392
0.020
Why?
Chemokine CXCL2
1
2011
41
0.020
Why?
Corneal Ulcer
1
2011
20
0.020
Why?
Epithelium, Corneal
1
2011
41
0.020
Why?
RNA, Small Interfering
1
2013
631
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
2
2003
973
0.020
Why?
Genome
1
2013
305
0.020
Why?
Bacterial Adhesion
1
2011
110
0.020
Why?
Methacrylates
1
2011
119
0.020
Why?
Anti-Infective Agents
1
2013
242
0.020
Why?
Disease Progression
1
2018
2847
0.020
Why?
Cell Adhesion
1
2011
452
0.020
Why?
Rabbits
1
2011
651
0.020
Why?
Cell Line
2
2008
2821
0.020
Why?
Prognosis
1
2018
4312
0.020
Why?
Granulocytes
1
2008
81
0.020
Why?
Follow-Up Studies
1
2018
5414
0.020
Why?
Nitric Oxide
1
2013
894
0.020
Why?
Enzyme Induction
1
2008
88
0.020
Why?
Colorado
1
2018
4558
0.020
Why?
Nitric Oxide Synthase Type II
1
2008
161
0.020
Why?
Pyridines
2
2002
603
0.020
Why?
Acute Lung Injury
1
2011
301
0.020
Why?
Cystic Fibrosis Transmembrane Conductance Regulator
1
2011
371
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
1
2008
238
0.020
Why?
Toll-Like Receptor 3
1
2007
30
0.020
Why?
NF-KappaB Inhibitor alpha
1
2006
49
0.020
Why?
Mitogen-Activated Protein Kinase Kinases
1
2007
126
0.020
Why?
I-kappa B Proteins
1
2006
74
0.020
Why?
Cell Proliferation
1
2013
2489
0.010
Why?
Keratinocytes
1
2007
250
0.010
Why?
Jurkat Cells
1
2005
114
0.010
Why?
Child
2
2020
22600
0.010
Why?
Cyclodextrins
1
2004
11
0.010
Why?
rac GTP-Binding Proteins
1
2004
35
0.010
Why?
Vital Capacity
1
2005
290
0.010
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
1
2005
161
0.010
Why?
Receptors, Interleukin-8B
1
2004
23
0.010
Why?
Syk Kinase
1
2003
19
0.010
Why?
Forced Expiratory Volume
1
2005
448
0.010
Why?
rho GTP-Binding Proteins
1
2004
56
0.010
Why?
Anthracenes
1
2003
31
0.010
Why?
Chemokine CXCL12
1
2004
86
0.010
Why?
Cells, Cultured
1
2011
4110
0.010
Why?
Chemokines
1
2004
218
0.010
Why?
Promoter Regions, Genetic
1
2008
1246
0.010
Why?
Cross-Sectional Studies
1
2015
5870
0.010
Why?
Dexamethasone
1
2005
366
0.010
Why?
DNA Primers
1
2003
507
0.010
Why?
Precipitin Tests
1
2002
90
0.010
Why?
Bone Marrow Cells
1
2004
321
0.010
Why?
Analysis of Variance
1
2005
1301
0.010
Why?
Cholesterol
1
2004
404
0.010
Why?
Protein Phosphatase 2
1
2002
41
0.010
Why?
Cell Survival
1
2005
1092
0.010
Why?
Electrophoresis, Gel, Two-Dimensional
1
2002
110
0.010
Why?
Ligands
1
2004
662
0.010
Why?
Intubation, Gastrointestinal
1
2002
81
0.010
Why?
Aminopyridines
1
2002
129
0.010
Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
1
2002
141
0.010
Why?
Transcription Factor AP-1
1
2002
79
0.010
Why?
Anti-Inflammatory Agents
1
2005
477
0.010
Why?
Epithelial Cells
1
2008
1106
0.010
Why?
Intracellular Signaling Peptides and Proteins
1
2003
454
0.010
Why?
Adolescent
1
2020
22409
0.010
Why?
Drug Administration Schedule
1
2002
779
0.010
Why?
In Vitro Techniques
1
2002
1046
0.010
Why?
Base Sequence
1
2003
2177
0.010
Why?
Homeostasis
1
2004
639
0.010
Why?
Amino Acid Sequence
1
2002
2136
0.010
Why?
Proteome
1
2002
515
0.010
Why?
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