Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Kenneth Malcolm

Concepts (316)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Mycobacterium abscessus
12
2026
110
4.140
Why?
Mycobacterium Infections, Nontuberculous
17
2026
339
3.260
Why?
Neutrophils
30
2025
1127
2.650
Why?
Host-Pathogen Interactions
4
2025
361
1.710
Why?
Cystic Fibrosis
17
2026
1163
1.630
Why?
Phagocytosis
8
2026
296
1.090
Why?
Azithromycin
4
2020
101
0.830
Why?
Immunity, Humoral
1
2025
118
0.820
Why?
Interferons
2
2016
186
0.750
Why?
Lipopolysaccharides
11
2025
858
0.730
Why?
Gene Expression Regulation
7
2020
2601
0.680
Why?
Immunity, Innate
3
2025
835
0.620
Why?
Anti-Bacterial Agents
12
2026
1925
0.600
Why?
Klebsiella pneumoniae
2
2018
47
0.580
Why?
Pseudomonas aeruginosa
9
2026
397
0.580
Why?
Pseudomonas
1
2018
30
0.570
Why?
Fomites
1
2017
6
0.530
Why?
Nontuberculous Mycobacteria
7
2025
189
0.520
Why?
Cytotoxicity, Immunologic
1
2018
224
0.520
Why?
Tobramycin
5
2026
63
0.430
Why?
Mitogen-Activated Protein Kinases
7
2004
288
0.390
Why?
Pseudomonas Infections
5
2022
231
0.380
Why?
Myelodysplastic Syndromes
2
2026
165
0.370
Why?
Mycobacterium Infections
1
2013
55
0.370
Why?
Neutrophil Activation
1
2013
84
0.370
Why?
Reactive Oxygen Species
4
2020
611
0.370
Why?
Bacteria
1
2018
766
0.350
Why?
Staphylococcus aureus
3
2015
454
0.350
Why?
Mycobacterium
1
2013
101
0.350
Why?
Superoxides
5
2018
198
0.340
Why?
Sputum
5
2025
302
0.320
Why?
Microbial Viability
3
2018
83
0.300
Why?
Immunoglobulin G
2
2025
892
0.290
Why?
Biofilms
5
2014
292
0.270
Why?
Extracellular Traps
2
2018
52
0.260
Why?
Macrophages
6
2026
1507
0.260
Why?
Humans
47
2026
145783
0.240
Why?
Immunoglobulin M
2
2025
265
0.240
Why?
Interleukin-8
3
2020
269
0.240
Why?
Mannose-Binding Lectin
1
2025
20
0.220
Why?
Phage Therapy
1
2025
17
0.220
Why?
Extracellular Space
2
2018
117
0.210
Why?
Gene Expression Profiling
3
2018
1777
0.210
Why?
Cell Separation
3
2016
306
0.210
Why?
Oligonucleotide Array Sequence Analysis
3
2002
751
0.210
Why?
Antibodies, Bacterial
1
2025
147
0.210
Why?
Complement C3
1
2025
187
0.200
Why?
Toll-Like Receptors
3
2017
193
0.180
Why?
Cytokines
8
2018
2069
0.180
Why?
GTP-Binding Proteins
1
2003
153
0.180
Why?
Antimalarials
1
2022
35
0.180
Why?
p38 Mitogen-Activated Protein Kinases
7
2011
264
0.180
Why?
Primary Cell Culture
2
2020
172
0.180
Why?
Complement Activation
1
2025
399
0.170
Why?
Disease Models, Animal
6
2026
4568
0.170
Why?
Case-Control Studies
3
2020
3634
0.170
Why?
Pneumonia, Bacterial
3
2013
113
0.170
Why?
Chemokine CCL4
1
2020
31
0.160
Why?
Bacteriophages
1
2022
110
0.160
Why?
Chloroquine
1
2020
54
0.160
Why?
RNA Splicing
2
2023
284
0.160
Why?
Bacterial Proteins
1
2026
968
0.150
Why?
Mice
16
2026
18355
0.150
Why?
Mycobacterium tuberculosis
1
2022
318
0.150
Why?
Sirolimus
1
2020
282
0.140
Why?
Transcription Factors
1
2026
1736
0.140
Why?
Intracellular Space
1
2018
64
0.130
Why?
Autophagy
1
2020
291
0.130
Why?
Respiratory System
1
2018
150
0.130
Why?
Adaptor Proteins, Signal Transducing
1
2020
426
0.130
Why?
Lung
9
2024
4116
0.130
Why?
Aztreonam
1
2016
11
0.130
Why?
Antiviral Agents
1
2003
769
0.120
Why?
Leukemia, Myeloid, Acute
1
2023
688
0.120
Why?
Signal Transduction
3
2020
5224
0.120
Why?
C-Reactive Protein
1
2018
423
0.110
Why?
Survival Analysis
2
2016
1378
0.110
Why?
Immunosuppressive Agents
1
2020
838
0.110
Why?
Interferon-alpha
1
2016
193
0.110
Why?
Alternative Splicing
1
2017
248
0.110
Why?
Animals
17
2026
38101
0.110
Why?
Microbial Sensitivity Tests
4
2022
365
0.110
Why?
Antimicrobial Cationic Peptides
1
2015
81
0.110
Why?
Severity of Illness Index
4
2018
2933
0.110
Why?
Granulomatous Disease, Chronic
1
2014
49
0.110
Why?
Leukocytes, Mononuclear
1
2017
574
0.110
Why?
RNA, Messenger
3
2022
2805
0.100
Why?
Oxidants
1
2014
99
0.100
Why?
Cell Movement
4
2013
963
0.100
Why?
Metalloproteases
1
2014
42
0.100
Why?
Phagocytes
1
2014
80
0.100
Why?
Deoxyribonucleases
2
2011
24
0.100
Why?
Kaplan-Meier Estimate
1
2016
971
0.100
Why?
Thiazolidinediones
1
2014
143
0.100
Why?
Quorum Sensing
1
2014
80
0.100
Why?
Odds Ratio
1
2016
1083
0.100
Why?
Tumor Necrosis Factor-alpha
5
2011
1217
0.100
Why?
Cell Death
2
2013
382
0.100
Why?
Rhinitis
1
2015
169
0.090
Why?
Virulence Factors
1
2014
175
0.090
Why?
Male
14
2026
73010
0.090
Why?
Multivariate Analysis
1
2016
1547
0.090
Why?
Prospective Studies
5
2025
8078
0.090
Why?
Wound Infection
1
2013
60
0.090
Why?
Sinusitis
1
2015
227
0.090
Why?
Cellular Structures
1
2011
6
0.090
Why?
Lipid Metabolism
1
2015
529
0.090
Why?
Contact Lenses, Hydrophilic
1
2011
7
0.080
Why?
Neutrophil Infiltration
3
2013
107
0.080
Why?
Myocytes, Smooth Muscle
1
2013
271
0.080
Why?
Actins
3
2009
426
0.080
Why?
Chemokine CXCL5
1
2011
19
0.080
Why?
Cell Lineage
1
2013
378
0.080
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
1
2013
298
0.080
Why?
Female
13
2026
79045
0.080
Why?
Eye Infections, Bacterial
1
2011
45
0.080
Why?
Treatment Outcome
4
2025
11794
0.080
Why?
Interleukin-17
1
2011
120
0.080
Why?
Species Specificity
1
2011
546
0.080
Why?
Lipids
1
2015
707
0.080
Why?
Biomarkers
4
2025
4302
0.080
Why?
Viruses
1
2011
166
0.070
Why?
Tumor Suppressor Protein p53
1
2013
534
0.070
Why?
Retroviridae
1
2008
100
0.070
Why?
cdc42 GTP-Binding Protein
2
2006
21
0.070
Why?
Pulmonary Alveoli
1
2011
387
0.070
Why?
Peptides
2
2011
999
0.070
Why?
Transgenes
1
2008
190
0.070
Why?
Mitochondria
1
2014
993
0.070
Why?
Burns
1
2013
374
0.070
Why?
Kruppel-Like Transcription Factors
1
2008
83
0.060
Why?
Pulmonary Artery
1
2013
1129
0.060
Why?
Adult
8
2025
40881
0.060
Why?
Bone Marrow
1
2008
307
0.060
Why?
Adaptor Proteins, Vesicular Transport
1
2007
45
0.060
Why?
Membrane Glycoproteins
2
2014
499
0.060
Why?
Endothelium, Vascular
1
2013
956
0.060
Why?
rhoA GTP-Binding Protein
1
2006
76
0.060
Why?
Escherichia coli Infections
1
2007
125
0.060
Why?
Up-Regulation
3
2006
848
0.060
Why?
Cohort Studies
2
2020
6033
0.060
Why?
Cell Culture Techniques
1
2008
375
0.060
Why?
Middle Aged
4
2020
36309
0.060
Why?
Inflammation
5
2022
2884
0.060
Why?
Hydroxyeicosatetraenoic Acids
1
2005
35
0.060
Why?
Respiratory Mucosa
1
2008
322
0.050
Why?
MAP Kinase Signaling System
1
2007
308
0.050
Why?
Toll-Like Receptor 4
2
2007
276
0.050
Why?
DNA
2
2009
1437
0.050
Why?
Dinoprostone
1
2005
180
0.050
Why?
Hydrogen Peroxide
1
2026
335
0.050
Why?
Drug Therapy, Combination
3
2013
1043
0.050
Why?
Transcription, Genetic
4
2008
1454
0.050
Why?
Membrane Microdomains
1
2004
34
0.050
Why?
Inflammation Mediators
2
2011
507
0.050
Why?
beta-Cyclodextrins
1
2004
32
0.050
Why?
NF-kappa B
4
2013
667
0.050
Why?
Enzyme Precursors
1
2003
15
0.050
Why?
Chemokines, CXC
1
2004
68
0.050
Why?
Gene Expression Regulation, Bacterial
1
2026
337
0.050
Why?
Receptors, CXCR4
1
2004
91
0.050
Why?
Mutation
2
2026
4090
0.050
Why?
Zymosan
1
2023
39
0.050
Why?
Splicing Factor U2AF
1
2023
18
0.050
Why?
Multicenter Studies as Topic
1
2025
413
0.050
Why?
Drug Evaluation, Preclinical
1
2024
196
0.050
Why?
Myxovirus Resistance Proteins
1
2003
13
0.050
Why?
Mycobacterium avium
1
2023
21
0.050
Why?
eIF-2 Kinase
1
2003
28
0.050
Why?
Bacterial Load
2
2015
67
0.050
Why?
Young Adult
3
2020
14254
0.050
Why?
Chemotaxis
1
2023
122
0.050
Why?
STAT1 Transcription Factor
1
2003
66
0.050
Why?
Enzyme Activation
4
2008
762
0.050
Why?
Anti-Inflammatory Agents, Non-Steroidal
2
2002
346
0.050
Why?
Escherichia coli
1
2007
835
0.050
Why?
Phosphoprotein Phosphatases
1
2002
66
0.050
Why?
Macrophages, Alveolar
1
2005
373
0.040
Why?
Cell Differentiation
2
2026
2050
0.040
Why?
Toll-Like Receptor 2
1
2003
125
0.040
Why?
Interferon Type I
1
2003
147
0.040
Why?
Risk Factors
1
2016
10919
0.040
Why?
Gene Expression
2
2008
1478
0.040
Why?
Phosphatidylinositol 3-Kinases
1
2003
383
0.040
Why?
STAT3 Transcription Factor
1
2003
206
0.040
Why?
Transcriptional Activation
2
2013
372
0.040
Why?
Ciprofloxacin
2
2013
31
0.040
Why?
Gene Expression Regulation, Enzymologic
1
2002
267
0.040
Why?
Receptors, Cell Surface
1
2003
372
0.040
Why?
Administration, Inhalation
1
2022
571
0.040
Why?
Apoptosis
2
2008
2444
0.040
Why?
Protein-Tyrosine Kinases
1
2003
431
0.040
Why?
Trans-Activators
1
2003
396
0.040
Why?
Glycolipids
1
2020
53
0.040
Why?
Clinical Trials as Topic
1
2025
1062
0.040
Why?
Mice, Knockout
3
2014
3130
0.040
Why?
Complement System Proteins
1
2023
314
0.040
Why?
Transforming Growth Factor beta
1
2002
474
0.040
Why?
Aged, 80 and over
1
2011
8347
0.040
Why?
Time Factors
3
2018
7134
0.030
Why?
British Columbia
1
2018
25
0.030
Why?
Bronchoalveolar Lavage Fluid
2
2015
638
0.030
Why?
Mice, Transgenic
1
2023
2191
0.030
Why?
Chemokine CXCL1
2
2011
76
0.030
Why?
Cell Migration Inhibition
2
2011
16
0.030
Why?
Chemotaxis, Leukocyte
2
2011
115
0.030
Why?
Morbidity
1
2018
322
0.030
Why?
Drug Administration Routes
1
2016
42
0.030
Why?
Imidazoles
3
2002
247
0.030
Why?
RNA Precursors
1
2017
154
0.030
Why?
Proteins
1
2002
1023
0.030
Why?
Mice, Inbred C57BL
4
2011
5992
0.030
Why?
DNA-Binding Proteins
1
2003
1482
0.030
Why?
Cathelicidins
1
2015
40
0.030
Why?
Drug Interactions
1
2016
405
0.030
Why?
NADPH Oxidase 2
1
2014
32
0.030
Why?
Aged
2
2015
26217
0.030
Why?
Respiratory Function Tests
1
2016
544
0.030
Why?
Predictive Value of Tests
1
2020
2123
0.030
Why?
Chronic Disease
2
2015
1812
0.030
Why?
Gentamicins
1
2015
50
0.030
Why?
Enzyme Inhibitors
3
2002
821
0.030
Why?
Reproducibility of Results
1
2002
3418
0.030
Why?
Pilot Projects
1
2020
1898
0.030
Why?
NADPH Oxidases
1
2014
122
0.030
Why?
Drug Resistance, Multiple, Bacterial
1
2014
77
0.030
Why?
Drug Resistance, Bacterial
1
2015
185
0.030
Why?
Recombinant Proteins
2
2011
1368
0.020
Why?
PPAR gamma
1
2014
182
0.020
Why?
Asthma
1
2005
1797
0.020
Why?
Survival Rate
1
2018
2094
0.020
Why?
Drug Monitoring
1
2016
401
0.020
Why?
JNK Mitogen-Activated Protein Kinases
2
2003
153
0.020
Why?
Spleen
1
2015
508
0.020
Why?
Chemokine CCL2
2
2003
112
0.020
Why?
Adenoviridae
1
2013
199
0.020
Why?
Leukocyte Count
1
2013
318
0.020
Why?
Cell Hypoxia
1
2013
247
0.020
Why?
Gene Knockdown Techniques
1
2013
334
0.020
Why?
Fibrinogen
1
2013
180
0.020
Why?
Down-Regulation
2
2006
618
0.020
Why?
Drug Synergism
1
2013
354
0.020
Why?
Neovascularization, Physiologic
1
2013
193
0.020
Why?
Monocytes
1
2014
539
0.020
Why?
Suspensions
1
2011
28
0.020
Why?
Gene Deletion
1
2013
392
0.020
Why?
Chemokine CXCL2
1
2011
41
0.020
Why?
Corneal Ulcer
1
2011
20
0.020
Why?
Epithelium, Corneal
1
2011
41
0.020
Why?
RNA, Small Interfering
1
2013
638
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
2
2003
979
0.020
Why?
Genome
1
2013
305
0.020
Why?
Bacterial Adhesion
1
2011
109
0.020
Why?
Methacrylates
1
2011
119
0.020
Why?
Anti-Infective Agents
1
2013
232
0.020
Why?
Disease Progression
1
2018
2865
0.020
Why?
Cell Adhesion
1
2011
451
0.020
Why?
Rabbits
1
2011
653
0.020
Why?
Cell Line
2
2008
2823
0.020
Why?
Prognosis
1
2018
4330
0.020
Why?
Granulocytes
1
2008
82
0.020
Why?
Follow-Up Studies
1
2018
5428
0.020
Why?
Nitric Oxide
1
2013
892
0.020
Why?
Enzyme Induction
1
2008
88
0.020
Why?
Colorado
1
2018
4556
0.020
Why?
Pyridines
2
2002
609
0.020
Why?
Nitric Oxide Synthase Type II
1
2008
162
0.020
Why?
Cystic Fibrosis Transmembrane Conductance Regulator
1
2011
373
0.020
Why?
Acute Lung Injury
1
2011
307
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
1
2008
241
0.020
Why?
Toll-Like Receptor 3
1
2007
30
0.020
Why?
NF-KappaB Inhibitor alpha
1
2006
50
0.020
Why?
Mitogen-Activated Protein Kinase Kinases
1
2007
126
0.020
Why?
I-kappa B Proteins
1
2006
75
0.010
Why?
Cell Proliferation
1
2013
2514
0.010
Why?
Keratinocytes
1
2007
249
0.010
Why?
Jurkat Cells
1
2005
115
0.010
Why?
Child
2
2020
22740
0.010
Why?
Cyclodextrins
1
2004
11
0.010
Why?
rac GTP-Binding Proteins
1
2004
35
0.010
Why?
Vital Capacity
1
2005
292
0.010
Why?
Granulocyte-Macrophage Colony-Stimulating Factor
1
2005
161
0.010
Why?
Syk Kinase
1
2003
19
0.010
Why?
Receptors, Interleukin-8B
1
2004
29
0.010
Why?
Forced Expiratory Volume
1
2005
450
0.010
Why?
rho GTP-Binding Proteins
1
2004
56
0.010
Why?
Anthracenes
1
2003
31
0.010
Why?
Chemokine CXCL12
1
2004
86
0.010
Why?
Cells, Cultured
1
2011
4151
0.010
Why?
Promoter Regions, Genetic
1
2008
1247
0.010
Why?
Chemokines
1
2004
217
0.010
Why?
Dexamethasone
1
2005
365
0.010
Why?
Cross-Sectional Studies
1
2015
5925
0.010
Why?
DNA Primers
1
2003
505
0.010
Why?
Bone Marrow Cells
1
2004
322
0.010
Why?
Precipitin Tests
1
2002
90
0.010
Why?
Analysis of Variance
1
2005
1300
0.010
Why?
Cholesterol
1
2004
408
0.010
Why?
Protein Phosphatase 2
1
2002
41
0.010
Why?
Electrophoresis, Gel, Two-Dimensional
1
2002
110
0.010
Why?
Cell Survival
1
2005
1104
0.010
Why?
Intubation, Gastrointestinal
1
2002
81
0.010
Why?
Ligands
1
2004
668
0.010
Why?
Aminopyridines
1
2002
129
0.010
Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
1
2002
143
0.010
Why?
Transcription Factor AP-1
1
2002
79
0.010
Why?
Anti-Inflammatory Agents
1
2005
478
0.010
Why?
Epithelial Cells
1
2008
1134
0.010
Why?
Intracellular Signaling Peptides and Proteins
1
2003
457
0.010
Why?
Drug Administration Schedule
1
2002
782
0.010
Why?
Adolescent
1
2020
22577
0.010
Why?
Base Sequence
1
2003
2171
0.010
Why?
In Vitro Techniques
1
2002
1049
0.010
Why?
Homeostasis
1
2004
644
0.010
Why?
Amino Acid Sequence
1
2002
2131
0.010
Why?
Proteome
1
2002
513
0.010
Why?
Malcolm's Networks
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