Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Tentler

Concepts (387)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Pyrimidines
8
2020
376
1.620
Why?
Xenograft Model Antitumor Assays
21
2020
698
1.420
Why?
Triple Negative Breast Neoplasms
5
2020
157
1.400
Why?
Protein Kinase Inhibitors
15
2020
785
1.390
Why?
Antineoplastic Agents
18
2019
1879
1.300
Why?
Colorectal Neoplasms
11
2018
615
1.130
Why?
Proto-Oncogene Proteins
10
2018
608
1.000
Why?
Azepines
4
2020
75
0.920
Why?
Piperazines
4
2020
309
0.910
Why?
Pyrazoles
4
2018
362
0.860
Why?
Melanoma
10
2018
620
0.860
Why?
Quinoxalines
2
2020
60
0.860
Why?
Gene Expression Regulation, Neoplastic
9
2020
1141
0.840
Why?
Mice, Nude
16
2020
630
0.730
Why?
Cell Proliferation
21
2020
2186
0.690
Why?
Lymphocytes, Tumor-Infiltrating
1
2020
111
0.680
Why?
beta Catenin
2
2020
219
0.670
Why?
Enoyl-CoA Hydratase
1
2018
9
0.640
Why?
DNA-Binding Proteins
8
2015
1314
0.600
Why?
Cell Line, Tumor
24
2020
2710
0.600
Why?
Tumor Microenvironment
1
2020
430
0.590
Why?
Benzimidazoles
4
2013
138
0.550
Why?
Mutation
11
2018
3345
0.540
Why?
Cardiomyopathy, Dilated
1
2018
348
0.510
Why?
Tumor Suppressor Proteins
2
2015
282
0.500
Why?
Tumor Suppressor Protein p53
4
2016
445
0.500
Why?
Genomics
1
2018
635
0.460
Why?
ras Proteins
3
2013
138
0.450
Why?
Pyrazines
5
2013
71
0.440
Why?
Proto-Oncogene Proteins B-raf
4
2018
192
0.410
Why?
Apoptosis
13
2020
2362
0.400
Why?
Oncogene Proteins, Fusion
3
2018
179
0.390
Why?
Biomarkers, Tumor
3
2017
1040
0.380
Why?
Mice
21
2020
14863
0.380
Why?
Drug Design
1
2012
148
0.370
Why?
Nuclear Proteins
1
2015
591
0.360
Why?
Prolactin
7
2004
96
0.350
Why?
Drug Resistance, Neoplasm
8
2020
636
0.350
Why?
Mitogen-Activated Protein Kinase Kinases
1
2010
113
0.350
Why?
Histone Deacetylase Inhibitors
3
2022
198
0.340
Why?
Aurora Kinase A
4
2020
51
0.340
Why?
Animals
44
2020
31698
0.320
Why?
Neoplasms
4
2022
2097
0.310
Why?
Cell Transformation, Neoplastic
4
2013
308
0.290
Why?
Imidazoles
4
2013
208
0.290
Why?
Pituitary Gland
7
2003
148
0.280
Why?
Ethanol
11
1997
538
0.270
Why?
Gene Expression Profiling
6
2018
1518
0.270
Why?
Hydroxamic Acids
3
2011
80
0.260
Why?
Antineoplastic Combined Chemotherapy Protocols
6
2020
1355
0.260
Why?
Exome
2
2017
200
0.250
Why?
Breast Neoplasms
3
2012
1862
0.250
Why?
Ubiquitin-Activating Enzymes
2
2016
13
0.240
Why?
Transcription Factors
4
2011
1528
0.240
Why?
Pyrimidinones
2
2015
88
0.240
Why?
Pyridones
2
2015
123
0.230
Why?
Receptor, IGF Type 1
3
2013
58
0.220
Why?
Humans
44
2022
114662
0.220
Why?
Cell Cycle Proteins
3
2018
551
0.210
Why?
Hypothalamus
12
1997
147
0.200
Why?
Immunoblotting
5
2015
283
0.200
Why?
Female
27
2020
59493
0.190
Why?
Drug Synergism
4
2018
316
0.190
Why?
Tumor Cells, Cultured
3
2020
849
0.190
Why?
c-Mer Tyrosine Kinase
2
2018
43
0.180
Why?
Transcription, Genetic
4
2013
1313
0.180
Why?
G2 Phase Cell Cycle Checkpoints
3
2018
41
0.180
Why?
Signal Transduction
10
2018
4512
0.180
Why?
Benzoxazoles
1
2020
16
0.180
Why?
Breast
3
2018
139
0.170
Why?
Wnt Signaling Pathway
2
2019
146
0.170
Why?
Boronic Acids
2
2011
33
0.170
Why?
Epithelial Cells
4
2011
950
0.170
Why?
Growth Hormone
3
1997
103
0.170
Why?
Sequence Analysis, RNA
2
2018
385
0.170
Why?
eIF-2 Kinase
1
2019
24
0.170
Why?
Proto-Oncogene Proteins p21(ras)
4
2016
228
0.160
Why?
Cell Cycle
7
2018
542
0.160
Why?
Breast Neoplasms, Male
1
2018
28
0.150
Why?
Cytochrome P-450 Enzyme System
1
2018
108
0.150
Why?
Linkage Disequilibrium
1
2018
245
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
68
0.150
Why?
Septins
1
2018
40
0.150
Why?
Mice, Inbred BALB C
1
2020
1143
0.150
Why?
Drug Therapy, Combination
1
2020
951
0.150
Why?
Cytoskeleton
1
2018
176
0.140
Why?
Genetics, Population
1
2018
188
0.140
Why?
Gonadotropin-Releasing Hormone
8
1993
188
0.140
Why?
Neurofibromin 1
1
2017
22
0.140
Why?
Somatostatin
1
1997
52
0.140
Why?
Armadillo Domain Proteins
1
2017
5
0.140
Why?
Gene Regulatory Networks
1
2018
228
0.140
Why?
Proto-Oncogene Proteins c-kit
1
2017
63
0.140
Why?
Adenine
1
2018
219
0.140
Why?
Testis
2
1997
133
0.140
Why?
RNA Splicing Factors
1
2017
49
0.140
Why?
Proto-Oncogene Proteins c-ret
1
2017
25
0.140
Why?
Cyclopentanes
1
2016
15
0.140
Why?
Sexual Maturation
1
1997
47
0.140
Why?
Inhibitory Concentration 50
2
2016
74
0.140
Why?
Cyclic AMP Response Element-Binding Protein
1
1997
127
0.140
Why?
Mucous Membrane
1
2017
108
0.140
Why?
RNA, Messenger
10
2003
2552
0.130
Why?
Cyclic AMP-Dependent Protein Kinases
1
1997
130
0.130
Why?
Genes, erbB-1
1
2016
17
0.130
Why?
Education, Graduate
1
2015
29
0.130
Why?
Skin Neoplasms
2
2013
756
0.130
Why?
Drug Discovery
1
2016
123
0.130
Why?
Oligonucleotide Array Sequence Analysis
3
2015
740
0.130
Why?
Peptides, Cyclic
1
1997
253
0.130
Why?
HT29 Cells
2
2018
35
0.130
Why?
Tumor Protein p73
1
2015
14
0.120
Why?
Proteasome Endopeptidase Complex
2
2013
133
0.120
Why?
Neoplasm Invasiveness
3
2018
442
0.120
Why?
Computational Biology
2
2016
530
0.120
Why?
Phosphoproteins
1
2017
298
0.120
Why?
Mitogen-Activated Protein Kinases
2
2014
278
0.120
Why?
Case-Control Studies
2
2018
3003
0.120
Why?
Luteinizing Hormone
8
1993
169
0.120
Why?
Testosterone
2
1997
343
0.120
Why?
Cluster Analysis
2
2012
455
0.110
Why?
Phosphorylation
5
2019
1569
0.110
Why?
Phenotype
3
2018
2796
0.110
Why?
Genotype
1
2018
1760
0.110
Why?
Protein Kinases
1
2015
307
0.110
Why?
Protein-Tyrosine Kinases
1
2017
395
0.110
Why?
Receptor, Insulin
1
2013
93
0.110
Why?
Mitochondria
1
2018
747
0.110
Why?
Cell Survival
4
2019
1021
0.110
Why?
Ubiquitin-Conjugating Enzymes
1
2013
9
0.110
Why?
Rats
21
2004
4958
0.110
Why?
Tumor Stem Cell Assay
1
2012
33
0.100
Why?
Aurora Kinases
1
2012
28
0.100
Why?
Cyclin-Dependent Kinase Inhibitor p16
1
2013
57
0.100
Why?
Alcohol Oxidoreductases
1
2013
38
0.100
Why?
Cyclosporine
1
2013
161
0.100
Why?
BRCA1 Protein
1
2013
56
0.100
Why?
Proto-Oncogene Proteins c-ets
4
2011
51
0.100
Why?
MicroRNAs
1
2018
600
0.100
Why?
Positron-Emission Tomography
2
2011
259
0.100
Why?
Receptor, ErbB-2
2
2012
300
0.100
Why?
Genes, p53
1
2012
61
0.100
Why?
TOR Serine-Threonine Kinases
1
2014
358
0.100
Why?
Proto-Oncogene Proteins c-met
1
2012
67
0.100
Why?
Ubiquitin-Protein Ligases
1
2013
139
0.100
Why?
Polymorphism, Single Nucleotide
1
2018
1879
0.090
Why?
Cellular Senescence
1
2012
152
0.090
Why?
Drug Screening Assays, Antitumor
4
2016
180
0.090
Why?
Proteasome Inhibitors
1
2011
40
0.090
Why?
Mammary Glands, Human
1
2011
60
0.090
Why?
Receptor Protein-Tyrosine Kinases
1
2013
226
0.090
Why?
Transcriptional Activation
2
2003
337
0.090
Why?
Cell Movement
3
2011
868
0.090
Why?
Cytoplasm
1
2011
255
0.090
Why?
Recombinant Fusion Proteins
2
2011
616
0.090
Why?
Protease Inhibitors
1
2011
97
0.090
Why?
Neoplasm Transplantation
3
2016
228
0.080
Why?
Vascular Endothelial Growth Factor Receptor-3
1
2009
6
0.080
Why?
Ki-67 Antigen
1
2010
103
0.080
Why?
Capillary Permeability
1
2010
139
0.080
Why?
Adenocarcinoma
1
2016
795
0.080
Why?
Carcinoma, Hepatocellular
1
2011
211
0.080
Why?
Vascular Endothelial Growth Factor Receptor-1
1
2009
66
0.080
Why?
Gastrointestinal Neoplasms
1
2009
59
0.080
Why?
Cell Line
4
2012
2636
0.080
Why?
Promoter Regions, Genetic
3
2004
1131
0.080
Why?
Quinazolines
1
2009
240
0.070
Why?
Algorithms
2
2015
1468
0.070
Why?
Prognosis
2
2017
3329
0.070
Why?
Peptide Fragments
1
2011
666
0.070
Why?
Drug Delivery Systems
1
2010
296
0.070
Why?
Enzyme Inhibitors
3
2013
750
0.070
Why?
Pituitary Gland, Anterior
4
1992
39
0.070
Why?
Disease Models, Animal
2
2014
3532
0.070
Why?
Colonic Neoplasms
1
2009
215
0.070
Why?
Reproducibility of Results
2
2010
2763
0.070
Why?
Proto-Oncogene Protein c-ets-1
2
2003
18
0.070
Why?
Male
25
2020
55583
0.060
Why?
Growth Hormone-Releasing Hormone
2
1997
26
0.060
Why?
Rats, Inbred Strains
12
1992
362
0.060
Why?
Transplantation, Heterologous
2
2016
181
0.060
Why?
Oncogene Protein p65(gag-jun)
1
2004
2
0.060
Why?
Gene Expression Regulation
2
2004
2319
0.060
Why?
Proto-Oncogene Proteins c-jun
1
2004
47
0.060
Why?
Pancreatic Neoplasms
1
2011
731
0.060
Why?
High-Throughput Nucleotide Sequencing
2
2017
439
0.060
Why?
Disease Progression
3
2018
2380
0.060
Why?
Transfection
2
2003
866
0.060
Why?
Lung Neoplasms
1
2016
2177
0.050
Why?
Middle Aged
6
2020
26733
0.050
Why?
Transcription Factor Pit-1
1
2003
24
0.050
Why?
Suppression, Genetic
1
2003
23
0.050
Why?
Mesoderm
1
2004
138
0.050
Why?
Genes, Dominant
1
2003
94
0.050
Why?
Aged
5
2020
19069
0.050
Why?
Histone Deacetylase 1
1
2022
16
0.050
Why?
DNA Repair
2
2013
184
0.050
Why?
Caspase 3
2
2013
235
0.050
Why?
DNA Damage
2
2013
351
0.050
Why?
Acetylation
1
2022
211
0.050
Why?
Blotting, Northern
3
1997
193
0.050
Why?
Repressor Proteins
1
2004
366
0.050
Why?
Radioimmunoassay
8
1993
162
0.040
Why?
Histone Deacetylases
1
2022
195
0.040
Why?
Bortezomib
2
2011
41
0.040
Why?
Mechanistic Target of Rapamycin Complex 2
1
2020
55
0.040
Why?
Maximum Tolerated Dose
1
2020
183
0.040
Why?
Mechanistic Target of Rapamycin Complex 1
1
2020
96
0.040
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2019
22
0.040
Why?
Blotting, Western
3
2010
1147
0.040
Why?
Gene Expression
3
1993
1421
0.040
Why?
Lymphocytes
2
1991
330
0.040
Why?
Azetidines
1
2018
31
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
23
0.040
Why?
Spleen
2
1991
487
0.040
Why?
GTP Phosphohydrolases
1
2018
65
0.040
Why?
4-Aminobenzoic Acid
1
2018
6
0.040
Why?
Nausea
1
2018
101
0.040
Why?
HCT116 Cells
1
2018
70
0.040
Why?
Enzyme-Linked Immunosorbent Assay
2
2010
797
0.040
Why?
Orchiectomy
4
1994
57
0.040
Why?
Okadaic Acid
1
1997
11
0.040
Why?
Colforsin
1
1997
48
0.040
Why?
Dose-Response Relationship, Drug
3
1997
1842
0.040
Why?
Piperidines
1
2018
160
0.040
Why?
Mutagenesis, Site-Directed
2
2011
345
0.040
Why?
Diarrhea
1
2018
171
0.040
Why?
Histones
1
2022
535
0.040
Why?
Tumor Burden
1
2018
259
0.030
Why?
Cell Differentiation
1
2004
1700
0.030
Why?
Treatment Outcome
1
2010
9088
0.030
Why?
Angiogenesis Inhibitors
1
2018
214
0.030
Why?
Cells, Cultured
4
2013
3885
0.030
Why?
Fatigue
1
2018
294
0.030
Why?
Ubiquitination
1
2016
86
0.030
Why?
Protein Isoforms
1
2017
338
0.030
Why?
Heterografts
1
2016
117
0.030
Why?
Administration, Oral
1
2018
728
0.030
Why?
Gene Rearrangement
1
2017
135
0.030
Why?
Aged, 80 and over
2
2017
6345
0.030
Why?
Cetuximab
1
2016
90
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
107
0.030
Why?
Camptothecin
1
2016
96
0.030
Why?
Polymerase Chain Reaction
3
1993
993
0.030
Why?
Capacity Building
1
2015
51
0.030
Why?
Models, Educational
1
2015
84
0.030
Why?
DNA Copy Number Variations
1
2016
154
0.030
Why?
Adult
4
2018
30544
0.030
Why?
Diphenylamine
1
2014
6
0.030
Why?
DNA Mutational Analysis
1
2016
372
0.030
Why?
Follicle Stimulating Hormone
2
1993
216
0.030
Why?
Biopsy
1
2018
1036
0.030
Why?
Interdisciplinary Communication
1
2015
183
0.030
Why?
Databases, Genetic
1
2015
206
0.030
Why?
Neoplasm Metastasis
1
2016
523
0.030
Why?
Guanine
1
1994
76
0.030
Why?
Research Personnel
1
2015
149
0.030
Why?
Methyltransferases
1
1994
61
0.030
Why?
Mentors
1
2015
156
0.030
Why?
Benzamides
1
2014
169
0.030
Why?
Analysis of Variance
1
1997
1226
0.030
Why?
Gonadotropins
1
1993
37
0.030
Why?
Caspase 7
1
2013
20
0.030
Why?
Butadienes
1
2013
30
0.030
Why?
MAP Kinase Kinase 2
1
2013
27
0.030
Why?
Program Development
1
2015
341
0.030
Why?
Kinetics
2
2014
1551
0.030
Why?
MAP Kinase Kinase 1
1
2013
66
0.030
Why?
Cell Cycle Checkpoints
1
2013
84
0.030
Why?
Cooperative Behavior
1
2015
381
0.030
Why?
Oncogene Proteins, Viral
1
2013
20
0.030
Why?
Molecular Sequence Data
3
2011
2785
0.030
Why?
Melanocytes
1
2013
55
0.030
Why?
Nitriles
1
2013
149
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p27
1
2013
69
0.030
Why?
Membrane Proteins
1
2018
1018
0.030
Why?
Phosphatidylinositol 3-Kinases
1
2014
329
0.030
Why?
Proto-Oncogene Proteins c-mdm2
1
2013
56
0.030
Why?
Genes, Synthetic
1
2012
14
0.030
Why?
Precision Medicine
1
2016
337
0.030
Why?
Genes, Lethal
1
2012
26
0.030
Why?
Drug Hypersensitivity
1
1993
83
0.030
Why?
DNA, Neoplasm
1
2013
157
0.030
Why?
Mice, SCID
1
2013
314
0.030
Why?
Ataxia Telangiectasia Mutated Proteins
1
2012
63
0.020
Why?
Nuclear Export Signals
1
2011
3
0.020
Why?
Glycoprotein Hormones, alpha Subunit
1
1991
22
0.020
Why?
Nuclear Localization Signals
1
2011
14
0.020
Why?
Alcoholic Intoxication
1
1992
62
0.020
Why?
Peptide Mapping
1
2011
60
0.020
Why?
Calcium Signaling
1
2013
217
0.020
Why?
Microscopy, Fluorescence
1
2013
396
0.020
Why?
Intercellular Signaling Peptides and Proteins
1
2013
351
0.020
Why?
Amino Acid Motifs
1
2011
197
0.020
Why?
Amino Acid Substitution
1
2011
262
0.020
Why?
Colony-Forming Units Assay
1
2010
88
0.020
Why?
Hypertension
1
2018
1056
0.020
Why?
Protein Biosynthesis
1
1992
385
0.020
Why?
Transcriptome
1
2015
725
0.020
Why?
Culture Media, Conditioned
1
2010
105
0.020
Why?
Genes, ras
1
2010
91
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
238
0.020
Why?
Protein Transport
1
2011
395
0.020
Why?
Ligands
1
2011
561
0.020
Why?
Curriculum
1
2015
819
0.020
Why?
Gene Dosage
1
2010
129
0.020
Why?
Drug Combinations
1
2010
287
0.020
Why?
Structure-Activity Relationship
1
2010
502
0.020
Why?
Gene Knockdown Techniques
1
2010
299
0.020
Why?
Prolactinoma
1
1989
11
0.020
Why?
Serum Albumin
1
1990
137
0.020
Why?
Protein Structure, Tertiary
1
2011
796
0.020
Why?
Magnetic Resonance Spectroscopy
1
2011
473
0.020
Why?
Immunohistochemistry
1
2013
1629
0.020
Why?
Cell Communication
1
2010
279
0.020
Why?
Follow-Up Studies
1
2017
4411
0.020
Why?
Rats, Sprague-Dawley
4
1994
2218
0.020
Why?
Proto-Oncogene Proteins c-akt
1
2010
398
0.020
Why?
Pregnanediones
1
1987
1
0.020
Why?
Sulfonamides
1
2011
445
0.020
Why?
Amino Acid Sequence
1
2011
1982
0.020
Why?
Pituitary Neoplasms
1
1989
157
0.020
Why?
Anesthetics
1
1987
54
0.020
Why?
Calcium
1
2013
1108
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2009
923
0.020
Why?
Feasibility Studies
1
2010
740
0.020
Why?
Brain Chemistry
1
1987
115
0.020
Why?
Liver Neoplasms
1
2011
506
0.020
Why?
Metabolomics
1
2011
521
0.020
Why?
Estrogens
1
1989
312
0.020
Why?
Models, Biological
1
2013
1620
0.020
Why?
Flow Cytometry
1
2009
1083
0.020
Why?
Prostatic Neoplasms
1
2013
921
0.020
Why?
Proto-Oncogene Protein c-ets-2
1
2004
3
0.010
Why?
Contact Inhibition
1
2004
3
0.010
Why?
Oncogene Protein p21(ras)
1
2004
16
0.010
Why?
Epidermal Growth Factor
1
2004
161
0.010
Why?
Antisense Elements (Genetics)
1
2003
4
0.010
Why?
Genetic Vectors
1
2004
289
0.010
Why?
Collagenases
1
2003
22
0.010
Why?
Matrix Metalloproteinase 3
1
2003
23
0.010
Why?
Cytokines
1
2010
1840
0.010
Why?
Cell Adhesion
1
2004
431
0.010
Why?
Cell Division
1
2004
758
0.010
Why?
Trans-Activators
1
2004
367
0.010
Why?
HeLa Cells
1
2003
562
0.010
Why?
Brain
1
1992
2371
0.010
Why?
Potassium
2
1990
128
0.010
Why?
Base Sequence
2
1993
2114
0.010
Why?
Biological Assay
2
1990
112
0.010
Why?
Hypophysectomy
2
1987
15
0.010
Why?
O(6)-Methylguanine-DNA Methyltransferase
1
1994
5
0.010
Why?
Cocarcinogenesis
1
1994
14
0.010
Why?
Injections, Intraperitoneal
1
1994
99
0.010
Why?
Rats, Mutant Strains
1
1993
25
0.010
Why?
Stress, Physiological
2
1987
378
0.010
Why?
Thyrotropin
1
1994
99
0.010
Why?
RNA-Directed DNA Polymerase
1
1993
34
0.010
Why?
Adrenocorticotropic Hormone
1
1994
128
0.010
Why?
Blotting, Southern
1
1992
68
0.010
Why?
Cyclic AMP
1
1992
227
0.010
Why?
Protein Kinase C
1
1992
273
0.010
Why?
Enzyme Activation
1
1992
785
0.010
Why?
RNA Splicing
1
1992
245
0.010
Why?
Cross Reactions
1
1990
117
0.010
Why?
Perfusion
1
1990
148
0.010
Why?
Dinoprostone
1
1990
184
0.010
Why?
Naloxone
1
1990
97
0.010
Why?
Bromocriptine
1
1989
26
0.010
Why?
Norepinephrine
1
1990
201
0.000
Why?
Chromatography, High Pressure Liquid
1
1990
470
0.000
Why?
Rats, Inbred F344
1
1989
241
0.000
Why?
Depression, Chemical
1
1987
22
0.000
Why?
In Vitro Techniques
1
1990
1016
0.000
Why?
Urethane
1
1987
41
0.000
Why?
Pancreas
1
1990
276
0.000
Why?
Dopamine
1
1990
236
0.000
Why?
Molecular Weight
1
1987
331
0.000
Why?
Drug Administration Schedule
1
1989
718
0.000
Why?
Cerebral Cortex
1
1990
380
0.000
Why?
Ketamine
1
1987
92
0.000
Why?
Alcoholism
1
1992
713
0.000
Why?
Restraint, Physical
1
1986
67
0.000
Why?
DNA
1
1991
1352
0.000
Why?
Kidney
1
1990
1188
0.000
Why?
Liver
1
1990
1637
0.000
Why?
Lung
1
1990
3559
0.000
Why?
Tentler's Networks
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