Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Tentler

Concepts (387)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Pyrimidines
8
2020
459
1.510
Why?
Xenograft Model Antitumor Assays
21
2020
814
1.330
Why?
Triple Negative Breast Neoplasms
5
2020
197
1.310
Why?
Protein Kinase Inhibitors
15
2020
891
1.310
Why?
Antineoplastic Agents
18
2019
2061
1.220
Why?
Colorectal Neoplasms
11
2018
752
1.030
Why?
Proto-Oncogene Proteins
10
2018
638
0.970
Why?
Azepines
4
2020
89
0.890
Why?
Piperazines
4
2020
342
0.870
Why?
Quinoxalines
2
2020
65
0.830
Why?
Pyrazoles
4
2018
405
0.820
Why?
Melanoma
10
2018
730
0.790
Why?
Gene Expression Regulation, Neoplastic
9
2020
1356
0.770
Why?
Mice, Nude
16
2020
683
0.700
Why?
Cell Proliferation
21
2020
2391
0.650
Why?
beta Catenin
2
2020
223
0.640
Why?
Enoyl-CoA Hydratase
1
2018
8
0.620
Why?
Lymphocytes, Tumor-Infiltrating
1
2020
211
0.600
Why?
DNA-Binding Proteins
8
2015
1443
0.560
Why?
Cell Line, Tumor
24
2020
3215
0.550
Why?
Benzimidazoles
4
2013
162
0.530
Why?
Tumor Microenvironment
1
2020
634
0.520
Why?
Mutation
11
2018
3717
0.500
Why?
Cardiomyopathy, Dilated
1
2018
381
0.480
Why?
Tumor Suppressor Proteins
2
2015
317
0.480
Why?
Tumor Suppressor Protein p53
4
2016
511
0.470
Why?
ras Proteins
3
2013
144
0.440
Why?
Genomics
1
2018
716
0.430
Why?
Pyrazines
5
2013
86
0.420
Why?
Proto-Oncogene Proteins B-raf
4
2018
212
0.400
Why?
Apoptosis
13
2020
2503
0.380
Why?
Oncogene Proteins, Fusion
3
2018
201
0.370
Why?
Drug Design
1
2012
156
0.360
Why?
Biomarkers, Tumor
3
2017
1181
0.360
Why?
Prolactin
7
2004
98
0.340
Why?
Mice
21
2020
16937
0.340
Why?
Mitogen-Activated Protein Kinase Kinases
1
2010
131
0.340
Why?
Nuclear Proteins
1
2015
663
0.340
Why?
Histone Deacetylase Inhibitors
3
2022
209
0.330
Why?
Drug Resistance, Neoplasm
8
2020
759
0.330
Why?
Aurora Kinase A
4
2020
55
0.330
Why?
Animals
44
2020
35362
0.290
Why?
Cell Transformation, Neoplastic
4
2013
328
0.280
Why?
Neoplasms
4
2022
2470
0.280
Why?
Imidazoles
4
2013
234
0.280
Why?
Pituitary Gland
7
2003
148
0.280
Why?
Hydroxamic Acids
3
2011
88
0.260
Why?
Ethanol
11
1997
589
0.250
Why?
Gene Expression Profiling
6
2018
1706
0.250
Why?
Exome
2
2017
220
0.240
Why?
Ubiquitin-Activating Enzymes
2
2016
16
0.240
Why?
Antineoplastic Combined Chemotherapy Protocols
6
2020
1565
0.230
Why?
Breast Neoplasms
3
2012
2142
0.230
Why?
Transcription Factors
4
2011
1651
0.230
Why?
Pyrimidinones
2
2015
103
0.230
Why?
Pyridones
2
2015
159
0.210
Why?
Receptor, IGF Type 1
3
2013
65
0.210
Why?
Cell Cycle Proteins
3
2018
586
0.200
Why?
Humans
44
2022
129650
0.200
Why?
Hypothalamus
12
1997
149
0.190
Why?
Immunoblotting
5
2015
305
0.190
Why?
Drug Synergism
4
2018
371
0.180
Why?
Tumor Cells, Cultured
3
2020
940
0.180
Why?
c-Mer Tyrosine Kinase
2
2018
44
0.180
Why?
G2 Phase Cell Cycle Checkpoints
3
2018
45
0.180
Why?
Female
27
2020
68776
0.170
Why?
Transcription, Genetic
4
2013
1418
0.170
Why?
Benzoxazoles
1
2020
20
0.170
Why?
Breast
3
2018
153
0.170
Why?
Boronic Acids
2
2011
37
0.170
Why?
Wnt Signaling Pathway
2
2019
170
0.170
Why?
Signal Transduction
10
2018
4925
0.160
Why?
Growth Hormone
3
1997
96
0.160
Why?
eIF-2 Kinase
1
2019
30
0.160
Why?
Sequence Analysis, RNA
2
2018
429
0.160
Why?
Epithelial Cells
4
2011
1065
0.160
Why?
Proto-Oncogene Proteins p21(ras)
4
2016
259
0.150
Why?
Cell Cycle
7
2018
592
0.150
Why?
Breast Neoplasms, Male
1
2018
29
0.150
Why?
Linkage Disequilibrium
1
2018
257
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
71
0.150
Why?
Cytochrome P-450 Enzyme System
1
2018
151
0.150
Why?
Septins
1
2018
43
0.140
Why?
Mice, Inbred BALB C
1
2020
1245
0.140
Why?
Drug Therapy, Combination
1
2020
1040
0.140
Why?
Genetics, Population
1
2018
200
0.140
Why?
Cytoskeleton
1
2018
183
0.140
Why?
Neurofibromin 1
1
2017
25
0.140
Why?
Gonadotropin-Releasing Hormone
8
1993
207
0.140
Why?
Somatostatin
1
1997
55
0.140
Why?
Armadillo Domain Proteins
1
2017
6
0.140
Why?
Testis
2
1997
144
0.130
Why?
RNA Splicing Factors
1
2017
52
0.130
Why?
Proto-Oncogene Proteins c-kit
1
2017
68
0.130
Why?
Proto-Oncogene Proteins c-ret
1
2017
30
0.130
Why?
Sexual Maturation
1
1997
52
0.130
Why?
Inhibitory Concentration 50
2
2016
86
0.130
Why?
Cyclopentanes
1
2016
19
0.130
Why?
Adenine
1
2018
256
0.130
Why?
Cyclic AMP Response Element-Binding Protein
1
1997
141
0.130
Why?
Gene Regulatory Networks
1
2018
284
0.130
Why?
Mucous Membrane
1
2017
122
0.130
Why?
Cyclic AMP-Dependent Protein Kinases
1
1997
133
0.130
Why?
Genes, erbB-1
1
2016
17
0.130
Why?
RNA, Messenger
10
2003
2708
0.130
Why?
Oligonucleotide Array Sequence Analysis
3
2015
769
0.120
Why?
Education, Graduate
1
2015
34
0.120
Why?
Drug Discovery
1
2016
131
0.120
Why?
HT29 Cells
2
2018
36
0.120
Why?
Peptides, Cyclic
1
1997
256
0.120
Why?
Skin Neoplasms
2
2013
825
0.120
Why?
Tumor Protein p73
1
2015
14
0.120
Why?
Proteasome Endopeptidase Complex
2
2013
148
0.120
Why?
Neoplasm Invasiveness
3
2018
485
0.120
Why?
Phosphoproteins
1
2017
332
0.120
Why?
Mitogen-Activated Protein Kinases
2
2014
312
0.120
Why?
Computational Biology
2
2016
599
0.110
Why?
Luteinizing Hormone
8
1993
179
0.110
Why?
Cluster Analysis
2
2012
482
0.110
Why?
Testosterone
2
1997
372
0.110
Why?
Case-Control Studies
2
2018
3381
0.110
Why?
Phosphorylation
5
2019
1713
0.110
Why?
Protein Kinases
1
2015
318
0.110
Why?
Genotype
1
2018
1839
0.110
Why?
Receptor, Insulin
1
2013
99
0.110
Why?
Protein-Tyrosine Kinases
1
2017
432
0.100
Why?
Phenotype
3
2018
3076
0.100
Why?
Ubiquitin-Conjugating Enzymes
1
2013
13
0.100
Why?
Cell Survival
4
2019
1086
0.100
Why?
Tumor Stem Cell Assay
1
2012
32
0.100
Why?
Aurora Kinases
1
2012
29
0.100
Why?
Cyclin-Dependent Kinase Inhibitor p16
1
2013
69
0.100
Why?
BRCA1 Protein
1
2013
65
0.100
Why?
Proto-Oncogene Proteins c-ets
4
2011
53
0.100
Why?
Alcohol Oxidoreductases
1
2013
60
0.100
Why?
Mitochondria
1
2018
877
0.100
Why?
Rats
21
2004
5500
0.100
Why?
Genes, p53
1
2012
70
0.100
Why?
Positron-Emission Tomography
2
2011
288
0.100
Why?
MicroRNAs
1
2018
678
0.100
Why?
Receptor, ErbB-2
2
2012
326
0.100
Why?
Cyclosporine
1
2013
263
0.100
Why?
TOR Serine-Threonine Kinases
1
2014
396
0.090
Why?
Proto-Oncogene Proteins c-met
1
2012
74
0.090
Why?
Ubiquitin-Protein Ligases
1
2013
153
0.090
Why?
Drug Screening Assays, Antitumor
4
2016
195
0.090
Why?
Proteasome Inhibitors
1
2011
42
0.090
Why?
Mammary Glands, Human
1
2011
64
0.090
Why?
Polymorphism, Single Nucleotide
1
2018
2073
0.090
Why?
Receptor Protein-Tyrosine Kinases
1
2013
231
0.090
Why?
Cellular Senescence
1
2012
181
0.090
Why?
Transcriptional Activation
2
2003
366
0.090
Why?
Cytoplasm
1
2011
263
0.090
Why?
Recombinant Fusion Proteins
2
2011
643
0.090
Why?
Cell Movement
3
2011
945
0.090
Why?
Protease Inhibitors
1
2011
106
0.090
Why?
Vascular Endothelial Growth Factor Receptor-3
1
2009
7
0.080
Why?
Ki-67 Antigen
1
2010
109
0.080
Why?
Neoplasm Transplantation
3
2016
257
0.080
Why?
Capillary Permeability
1
2010
139
0.080
Why?
Vascular Endothelial Growth Factor Receptor-1
1
2009
70
0.080
Why?
Adenocarcinoma
1
2016
898
0.080
Why?
Gastrointestinal Neoplasms
1
2009
72
0.080
Why?
Carcinoma, Hepatocellular
1
2011
272
0.080
Why?
Cell Line
4
2012
2781
0.080
Why?
Quinazolines
1
2009
244
0.070
Why?
Promoter Regions, Genetic
3
2004
1207
0.070
Why?
Peptide Fragments
1
2011
692
0.070
Why?
Algorithms
2
2015
1622
0.070
Why?
Drug Delivery Systems
1
2010
336
0.070
Why?
Enzyme Inhibitors
3
2013
827
0.070
Why?
Pituitary Gland, Anterior
4
1992
39
0.070
Why?
Prognosis
2
2017
3794
0.070
Why?
Colonic Neoplasms
1
2009
243
0.070
Why?
Proto-Oncogene Protein c-ets-1
2
2003
19
0.060
Why?
Disease Models, Animal
2
2014
4063
0.060
Why?
Reproducibility of Results
2
2010
3083
0.060
Why?
Growth Hormone-Releasing Hormone
2
1997
24
0.060
Why?
Rats, Inbred Strains
12
1992
368
0.060
Why?
Transplantation, Heterologous
2
2016
192
0.060
Why?
Oncogene Protein p65(gag-jun)
1
2004
2
0.060
Why?
Male
25
2020
63681
0.060
Why?
Proto-Oncogene Proteins c-jun
1
2004
52
0.060
Why?
Gene Expression Regulation
2
2004
2548
0.060
Why?
Transfection
2
2003
911
0.050
Why?
High-Throughput Nucleotide Sequencing
2
2017
487
0.050
Why?
Pancreatic Neoplasms
1
2011
882
0.050
Why?
Transcription Factor Pit-1
1
2003
24
0.050
Why?
Suppression, Genetic
1
2003
25
0.050
Why?
Disease Progression
3
2018
2635
0.050
Why?
Lung Neoplasms
1
2016
2344
0.050
Why?
Mesoderm
1
2004
137
0.050
Why?
Genes, Dominant
1
2003
92
0.050
Why?
Histone Deacetylase 1
1
2022
24
0.050
Why?
DNA Repair
2
2013
207
0.050
Why?
Middle Aged
6
2020
31154
0.050
Why?
Caspase 3
2
2013
245
0.050
Why?
Blotting, Northern
3
1997
200
0.050
Why?
Aged
5
2020
22103
0.050
Why?
DNA Damage
2
2013
384
0.050
Why?
Acetylation
1
2022
246
0.050
Why?
Repressor Proteins
1
2004
406
0.040
Why?
Radioimmunoassay
8
1993
175
0.040
Why?
Histone Deacetylases
1
2022
212
0.040
Why?
Bortezomib
2
2011
45
0.040
Why?
Mechanistic Target of Rapamycin Complex 2
1
2020
62
0.040
Why?
Maximum Tolerated Dose
1
2020
193
0.040
Why?
Mechanistic Target of Rapamycin Complex 1
1
2020
119
0.040
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2019
40
0.040
Why?
Blotting, Western
3
2010
1205
0.040
Why?
Gene Expression
3
1993
1472
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
24
0.040
Why?
Azetidines
1
2018
40
0.040
Why?
Spleen
2
1991
507
0.040
Why?
Lymphocytes
2
1991
377
0.040
Why?
GTP Phosphohydrolases
1
2018
85
0.040
Why?
4-Aminobenzoic Acid
1
2018
7
0.040
Why?
Nausea
1
2018
110
0.040
Why?
HCT116 Cells
1
2018
78
0.040
Why?
Okadaic Acid
1
1997
14
0.040
Why?
Orchiectomy
4
1994
67
0.040
Why?
Enzyme-Linked Immunosorbent Assay
2
2010
833
0.030
Why?
Colforsin
1
1997
50
0.030
Why?
Mutagenesis, Site-Directed
2
2011
361
0.030
Why?
Diarrhea
1
2018
180
0.030
Why?
Dose-Response Relationship, Drug
3
1997
2012
0.030
Why?
Piperidines
1
2018
199
0.030
Why?
Angiogenesis Inhibitors
1
2018
220
0.030
Why?
Tumor Burden
1
2018
286
0.030
Why?
Histones
1
2022
588
0.030
Why?
Cells, Cultured
4
2013
4083
0.030
Why?
Ubiquitination
1
2016
98
0.030
Why?
Cell Differentiation
1
2004
1902
0.030
Why?
Fatigue
1
2018
318
0.030
Why?
Heterografts
1
2016
131
0.030
Why?
Treatment Outcome
1
2010
10230
0.030
Why?
Cetuximab
1
2016
94
0.030
Why?
Administration, Oral
1
2018
786
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
117
0.030
Why?
Protein Isoforms
1
2017
391
0.030
Why?
Camptothecin
1
2016
109
0.030
Why?
Gene Rearrangement
1
2017
148
0.030
Why?
Polymerase Chain Reaction
3
1993
1038
0.030
Why?
Aged, 80 and over
2
2017
7086
0.030
Why?
Models, Educational
1
2015
88
0.030
Why?
Capacity Building
1
2015
59
0.030
Why?
DNA Copy Number Variations
1
2016
170
0.030
Why?
Diphenylamine
1
2014
9
0.030
Why?
DNA Mutational Analysis
1
2016
387
0.030
Why?
Biopsy
1
2018
1097
0.030
Why?
Interdisciplinary Communication
1
2015
186
0.030
Why?
Follicle Stimulating Hormone
2
1993
236
0.030
Why?
Databases, Genetic
1
2015
232
0.030
Why?
Guanine
1
1994
76
0.030
Why?
Research Personnel
1
2015
156
0.030
Why?
Neoplasm Metastasis
1
2016
610
0.030
Why?
Analysis of Variance
1
1997
1288
0.030
Why?
Methyltransferases
1
1994
70
0.030
Why?
Gonadotropins
1
1993
38
0.030
Why?
Benzamides
1
2014
207
0.030
Why?
Adult
4
2018
35576
0.030
Why?
Caspase 7
1
2013
22
0.030
Why?
Mentors
1
2015
178
0.030
Why?
Butadienes
1
2013
36
0.030
Why?
MAP Kinase Kinase 2
1
2013
29
0.030
Why?
Program Development
1
2015
357
0.030
Why?
MAP Kinase Kinase 1
1
2013
76
0.030
Why?
Kinetics
2
2014
1642
0.030
Why?
Cell Cycle Checkpoints
1
2013
95
0.030
Why?
Oncogene Proteins, Viral
1
2013
22
0.030
Why?
Molecular Sequence Data
3
2011
2832
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p27
1
2013
73
0.030
Why?
Cooperative Behavior
1
2015
433
0.030
Why?
Melanocytes
1
2013
64
0.030
Why?
Nitriles
1
2013
172
0.020
Why?
Drug Hypersensitivity
1
1993
81
0.020
Why?
Phosphatidylinositol 3-Kinases
1
2014
359
0.020
Why?
Genes, Synthetic
1
2012
14
0.020
Why?
Genes, Lethal
1
2012
29
0.020
Why?
Proto-Oncogene Proteins c-mdm2
1
2013
64
0.020
Why?
DNA, Neoplasm
1
2013
159
0.020
Why?
Membrane Proteins
1
2018
1119
0.020
Why?
Mice, SCID
1
2013
351
0.020
Why?
Ataxia Telangiectasia Mutated Proteins
1
2012
66
0.020
Why?
Precision Medicine
1
2016
387
0.020
Why?
Nuclear Export Signals
1
2011
4
0.020
Why?
Glycoprotein Hormones, alpha Subunit
1
1991
22
0.020
Why?
Nuclear Localization Signals
1
2011
15
0.020
Why?
Alcoholic Intoxication
1
1992
63
0.020
Why?
Peptide Mapping
1
2011
63
0.020
Why?
Microscopy, Fluorescence
1
2013
400
0.020
Why?
Intercellular Signaling Peptides and Proteins
1
2013
375
0.020
Why?
Calcium Signaling
1
2013
250
0.020
Why?
Amino Acid Motifs
1
2011
213
0.020
Why?
Colony-Forming Units Assay
1
2010
90
0.020
Why?
Amino Acid Substitution
1
2011
282
0.020
Why?
Culture Media, Conditioned
1
2010
110
0.020
Why?
Genes, ras
1
2010
97
0.020
Why?
Protein Biosynthesis
1
1992
406
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
257
0.020
Why?
Protein Transport
1
2011
428
0.020
Why?
Ligands
1
2011
622
0.020
Why?
Gene Dosage
1
2010
143
0.020
Why?
Drug Combinations
1
2010
330
0.020
Why?
Transcriptome
1
2015
887
0.020
Why?
Structure-Activity Relationship
1
2010
548
0.020
Why?
Gene Knockdown Techniques
1
2010
315
0.020
Why?
Hypertension
1
2018
1242
0.020
Why?
Curriculum
1
2015
917
0.020
Why?
Prolactinoma
1
1989
12
0.020
Why?
Serum Albumin
1
1990
149
0.020
Why?
Protein Structure, Tertiary
1
2011
840
0.020
Why?
Magnetic Resonance Spectroscopy
1
2011
539
0.020
Why?
Immunohistochemistry
1
2013
1698
0.020
Why?
Cell Communication
1
2010
301
0.020
Why?
Proto-Oncogene Proteins c-akt
1
2010
431
0.020
Why?
Follow-Up Studies
1
2017
4897
0.020
Why?
Pregnanediones
1
1987
7
0.020
Why?
Rats, Sprague-Dawley
4
1994
2406
0.020
Why?
Amino Acid Sequence
1
2011
2058
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2009
958
0.020
Why?
Sulfonamides
1
2011
496
0.020
Why?
Brain Chemistry
1
1987
118
0.020
Why?
Anesthetics
1
1987
66
0.020
Why?
Pituitary Neoplasms
1
1989
184
0.020
Why?
Calcium
1
2013
1213
0.020
Why?
Feasibility Studies
1
2010
868
0.020
Why?
Estrogens
1
1989
347
0.020
Why?
Liver Neoplasms
1
2011
640
0.020
Why?
Models, Biological
1
2013
1722
0.020
Why?
Metabolomics
1
2011
652
0.020
Why?
Flow Cytometry
1
2009
1156
0.020
Why?
Prostatic Neoplasms
1
2013
1016
0.010
Why?
Proto-Oncogene Protein c-ets-2
1
2004
3
0.010
Why?
Contact Inhibition
1
2004
5
0.010
Why?
Oncogene Protein p21(ras)
1
2004
16
0.010
Why?
Epidermal Growth Factor
1
2004
171
0.010
Why?
Antisense Elements (Genetics)
1
2003
4
0.010
Why?
Collagenases
1
2003
23
0.010
Why?
Matrix Metalloproteinase 3
1
2003
26
0.010
Why?
Genetic Vectors
1
2004
312
0.010
Why?
Cell Adhesion
1
2004
452
0.010
Why?
Cytokines
1
2010
2017
0.010
Why?
Cell Division
1
2004
797
0.010
Why?
Trans-Activators
1
2004
388
0.010
Why?
HeLa Cells
1
2003
608
0.010
Why?
Brain
1
1992
2679
0.010
Why?
Potassium
2
1990
143
0.010
Why?
Base Sequence
2
1993
2142
0.010
Why?
Biological Assay
2
1990
118
0.010
Why?
Hypophysectomy
2
1987
15
0.010
Why?
O(6)-Methylguanine-DNA Methyltransferase
1
1994
6
0.010
Why?
Cocarcinogenesis
1
1994
14
0.010
Why?
Injections, Intraperitoneal
1
1994
111
0.010
Why?
Rats, Mutant Strains
1
1993
24
0.010
Why?
Thyrotropin
1
1994
109
0.010
Why?
Stress, Physiological
2
1987
413
0.010
Why?
RNA-Directed DNA Polymerase
1
1993
34
0.010
Why?
Adrenocorticotropic Hormone
1
1994
133
0.010
Why?
Blotting, Southern
1
1992
69
0.010
Why?
Cyclic AMP
1
1992
237
0.010
Why?
Protein Kinase C
1
1992
259
0.010
Why?
Enzyme Activation
1
1992
811
0.010
Why?
RNA Splicing
1
1992
262
0.010
Why?
Cross Reactions
1
1990
132
0.010
Why?
Dinoprostone
1
1990
186
0.000
Why?
Bromocriptine
1
1989
29
0.000
Why?
Norepinephrine
1
1990
210
0.000
Why?
Perfusion
1
1990
197
0.000
Why?
Naloxone
1
1990
112
0.000
Why?
Rats, Inbred F344
1
1989
257
0.000
Why?
Depression, Chemical
1
1987
22
0.000
Why?
In Vitro Techniques
1
1990
1085
0.000
Why?
Chromatography, High Pressure Liquid
1
1990
582
0.000
Why?
Urethane
1
1987
41
0.000
Why?
Pancreas
1
1990
306
0.000
Why?
Molecular Weight
1
1987
332
0.000
Why?
Drug Administration Schedule
1
1989
769
0.000
Why?
Dopamine
1
1990
289
0.000
Why?
Ketamine
1
1987
85
0.000
Why?
Cerebral Cortex
1
1990
437
0.000
Why?
Alcoholism
1
1992
766
0.000
Why?
Restraint, Physical
1
1986
68
0.000
Why?
DNA
1
1991
1401
0.000
Why?
Kidney
1
1990
1385
0.000
Why?
Liver
1
1990
1839
0.000
Why?
Lung
1
1990
3930
0.000
Why?
Tentler's Networks
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