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Connection

John Tentler to Animals

This is a "connection" page, showing publications John Tentler has written about Animals.

 
Connection Strength
  
 
 
0.293
  
  1. Tentler JJ, Lang J, Capasso A, Kim DJ, Benaim E, Lee YB, Eisen A, Bagby SM, Hartman SJ, Yacob BW, Gittleman B, Pitts TM, Pelanda R, Eckhardt SG, Diamond JR. RX-5902, a novel ?-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer. BMC Cancer. 2020 Nov 04; 20(1):1063.
    View in: PubMed
    Score: 0.037
  2. Tentler JJ, Ionkina AA, Tan AC, Newton TP, Pitts TM, Glogowska MJ, Kabos P, Sartorius CA, Sullivan KD, Espinosa JM, Eckhardt SG, Diamond JR. p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer. Mol Cancer Ther. 2015 May; 14(5):1117-29.
    View in: PubMed
    Score: 0.025
  3. Diamond JR, Eckhardt SG, Tan AC, Newton TP, Selby HM, Brunkow KL, Kachaeva MI, Varella-Garcia M, Pitts TM, Bray MR, Fletcher GC, Tentler JJ. Predictive biomarkers of sensitivity to the aurora and angiogenic kinase inhibitor ENMD-2076 in preclinical breast cancer models. Clin Cancer Res. 2013 Jan 01; 19(1):291-303.
    View in: PubMed
    Score: 0.022
  4. Tentler JJ, Tan AC, Weekes CD, Jimeno A, Leong S, Pitts TM, Arcaroli JJ, Messersmith WA, Eckhardt SG. Patient-derived tumour xenografts as models for oncology drug development. Nat Rev Clin Oncol. 2012 Apr 17; 9(6):338-50.
    View in: PubMed
    Score: 0.021
  5. Tentler JJ, Nallapareddy S, Tan AC, Spreafico A, Pitts TM, Morelli MP, Selby HM, Kachaeva MI, Flanigan SA, Kulikowski GN, Leong S, Arcaroli JJ, Messersmith WA, Eckhardt SG. Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer. Mol Cancer Ther. 2010 Dec; 9(12):3351-62.
    View in: PubMed
    Score: 0.019
  6. Tentler JJ, Bradshaw-Pierce EL, Serkova NJ, Hasebroock KM, Pitts TM, Diamond JR, Fletcher GC, Bray MR, Eckhardt SG. Assessment of the in vivo antitumor effects of ENMD-2076, a novel multitargeted kinase inhibitor, against primary and cell line-derived human colorectal cancer xenograft models. Clin Cancer Res. 2010 Jun 01; 16(11):2989-2998.
    View in: PubMed
    Score: 0.018
  7. Davis SL, Ionkina AA, Bagby SM, Orth JD, Gittleman B, Marcus JM, Lam ET, Corr BR, O'Bryant CL, Glode AE, Tan AC, Kim J, Tentler JJ, Capasso A, Lopez KL, Gustafson DL, Messersmith WA, Leong S, Eckhardt SG, Pitts TM, Diamond JR. Preclinical and Dose-Finding Phase I Trial Results of Combined Treatment with a TORC1/2 Inhibitor (TAK-228) and Aurora A Kinase Inhibitor (Alisertib) in Solid Tumors. Clin Cancer Res. 2020 09 01; 26(17):4633-4642.
    View in: PubMed
    Score: 0.009
  8. Capasso A, Bagby SM, Dailey KL, Currimjee N, Yacob BW, Ionkina A, Frank JG, Kim DJ, George C, Lee YB, Benaim E, Gittleman B, Hartman SJ, Tan AC, Kim J, Pitts TM, Eckhardt SG, Tentler JJ, Diamond JR. First-in-Class Phosphorylated-p68 Inhibitor RX-5902 Inhibits ?-Catenin Signaling and Demonstrates Antitumor Activity in Triple-Negative Breast Cancer. Mol Cancer Ther. 2019 11; 18(11):1916-1925.
    View in: PubMed
    Score: 0.009
  9. Sinik L, Minson KA, Tentler JJ, Carrico J, Bagby SM, Robinson WA, Kami R, Burstyn-Cohen T, Eckhardt SG, Wang X, Frye SV, Earp HS, DeRyckere D, Graham DK. Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma. Mol Cancer Ther. 2019 02; 18(2):278-288.
    View in: PubMed
    Score: 0.008
  10. Capasso A, Pitts TM, Klauck PJ, Bagby SM, Westbrook L, Kaplan J, Soleimani M, Spreafico A, Tentler JJ, Diamond JR, Arcaroli JJ, Messersmith WA, Eckhardt SG, Leong S. Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models. Anticancer Drugs. 2018 10; 29(9):827-838.
    View in: PubMed
    Score: 0.008
  11. Klauck PJ, Bagby SM, Capasso A, Bradshaw-Pierce EL, Selby HM, Spreafico A, Tentler JJ, Tan AC, Kim J, Arcaroli JJ, Purkey A, Messersmith WA, Kuida K, Eckhardt SG, Pitts TM. Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer. BMC Cancer. 2018 02 05; 18(1):136.
    View in: PubMed
    Score: 0.008
  12. Couts KL, Bemis J, Turner JA, Bagby SM, Murphy D, Christiansen J, Hintzsche JD, Le A, Pitts TM, Wells K, Applegate A, Amato C, Multani P, Chow-Maneval E, Tentler JJ, Shellman YG, Rioth MJ, Tan AC, Gonzalez R, Medina T, Doebele RC, Robinson WA. ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms. Mol Cancer Ther. 2018 01; 17(1):222-231.
    View in: PubMed
    Score: 0.008
  13. Tentler JJ, Hadcock JR, Gutierrez-Hartmann A. Somatostatin acts by inhibiting the cyclic 3',5'-adenosine monophosphate (cAMP)/protein kinase A pathway, cAMP response element-binding protein (CREB) phosphorylation, and CREB transcription potency. Mol Endocrinol. 1997 Jun; 11(7):859-66.
    View in: PubMed
    Score: 0.007
  14. Tentler JJ, LaPaglia N, Steiner J, Williams D, Castelli M, Kelley MR, Emanuele NV, Emanuele MA. Ethanol, growth hormone and testosterone in peripubertal rats. J Endocrinol. 1997 Mar; 152(3):477-87.
    View in: PubMed
    Score: 0.007
  15. Bagby S, Messersmith WA, Pitts TM, Capasso A, Varella-Garcia M, Klauck PJ, Kim J, Tan AC, Eckhardt SG, Tentler JJ, Arcaroli J. Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies. J Vis Exp. 2016 09 30; (115).
    View in: PubMed
    Score: 0.007
  16. Pitts TM, Bradshaw-Pierce EL, Bagby SM, Hyatt SL, Selby HM, Spreafico A, Tentler JJ, McPhillips K, Klauck PJ, Capasso A, Diamond JR, Davis SL, Tan AC, Arcaroli JJ, Purkey A, Messersmith WA, Ecsedy JA, Eckhardt SG. Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer. Oncotarget. 2016 Aug 02; 7(31):50290-50301.
    View in: PubMed
    Score: 0.007
  17. Lieu CH, Klauck PJ, Henthorn PK, Tentler JJ, Tan AC, Spreafico A, Selby HM, Britt BC, Bagby SM, Arcaroli JJ, Messersmith WA, Pitts TM, Eckhardt SG. Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts. Oncotarget. 2015 Oct 27; 6(33):34561-72.
    View in: PubMed
    Score: 0.007
  18. Pitts TM, Newton TP, Bradshaw-Pierce EL, Addison R, Arcaroli JJ, Klauck PJ, Bagby SM, Hyatt SL, Purkey A, Tentler JJ, Tan AC, Messersmith WA, Eckhardt SG, Leong S. Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer. PLoS One. 2014; 9(11):e113037.
    View in: PubMed
    Score: 0.006
  19. Micel LN, Tentler JJ, Tan AC, Selby HM, Brunkow KL, Robertson KM, Davis SL, Klauck PJ, Pitts TM, Gangolli E, Fabrey R, O'Connell SM, Vincent PW, Eckhardt SG. Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants. Mol Cancer Ther. 2015 Feb; 14(2):317-25.
    View in: PubMed
    Score: 0.006
  20. Flanigan SA, Pitts TM, Newton TP, Kulikowski GN, Tan AC, McManus MC, Spreafico A, Kachaeva MI, Selby HM, Tentler JJ, Eckhardt SG, Leong S. Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models. Clin Cancer Res. 2013 Nov 15; 19(22):6219-29.
    View in: PubMed
    Score: 0.006
  21. Schlegel J, Sambade MJ, Sather S, Moschos SJ, Tan AC, Winges A, DeRyckere D, Carson CC, Trembath DG, Tentler JJ, Eckhardt SG, Kuan PF, Hamilton RL, Duncan LM, Miller CR, Nikolaishvili-Feinberg N, Midkiff BR, Liu J, Zhang W, Yang C, Wang X, Frye SV, Earp HS, Shields JM, Graham DK. MERTK receptor tyrosine kinase is a therapeutic target in melanoma. J Clin Invest. 2013 May; 123(5):2257-67.
    View in: PubMed
    Score: 0.006
  22. Morelli MP, Tentler JJ, Kulikowski GN, Tan AC, Bradshaw-Pierce EL, Pitts TM, Brown AM, Nallapareddy S, Arcaroli JJ, Serkova NJ, Hidalgo M, Ciardiello F, Eckhardt SG. Preclinical activity of the rational combination of selumetinib (AZD6244) in combination with vorinostat in KRAS-mutant colorectal cancer models. Clin Cancer Res. 2012 Feb 15; 18(4):1051-62.
    View in: PubMed
    Score: 0.005
  23. Flanigan SA, Pitts TM, Eckhardt SG, Tentler JJ, Tan AC, Thorburn A, Leong S. The insulin-like growth factor I receptor/insulin receptor tyrosine kinase inhibitor PQIP exhibits enhanced antitumor effects in combination with chemotherapy against colorectal cancer models. Clin Cancer Res. 2010 Nov 15; 16(22):5436-46.
    View in: PubMed
    Score: 0.005
  24. Poczobutt JM, Tentler J, Lu X, Schedin PJ, Gutierrez-Hartmann A. Benign mammary epithelial cells enhance the transformed phenotype of human breast cancer cells. BMC Cancer. 2010 Jul 16; 10:373.
    View in: PubMed
    Score: 0.005
  25. Pitts TM, Tan AC, Kulikowski GN, Tentler JJ, Brown AM, Flanigan SA, Leong S, Coldren CD, Hirsch FR, Varella-Garcia M, Korch C, Eckhardt SG. Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development. Clin Cancer Res. 2010 Jun 15; 16(12):3193-204.
    View in: PubMed
    Score: 0.005
  26. Farrow KN, Bradford AP, Tentler JJ, Gutierrez-Hartmann A. Structural and functional analysis of the differential effects of c-Jun and v-Jun on prolactin gene expression. Mol Endocrinol. 2004 Oct; 18(10):2479-90.
    View in: PubMed
    Score: 0.003
  27. Wilson DM, Tentler JJ, Carney JP, Wilson TM, Kelley MR. Acute ethanol exposure suppresses the repair of O6-methylguanine DNA lesions in castrated adult male rats. Alcohol Clin Exp Res. 1994 Oct; 18(5):1267-71.
    View in: PubMed
    Score: 0.002
  28. Halloran MM, Emanuele MA, Draski L, Tentler JJ, Emanuele NV, Kelley MR. Failure of ethanol to induce changes in gonadotropin gene expression in selectively bred ethanol-sensitive rats. Endocr Res. 1993 Dec; 19(4):317-29.
    View in: PubMed
    Score: 0.001
  29. Kelley MR, Jurgens JK, Tentler J, Emanuele NV, Blutt SE, Emanuele MA. Coupled reverse transcription-polymerase chain reaction (RT-PCR) technique is comparative, quantitative, and rapid: uses in alcohol research involving low abundance mRNA species such as hypothalamic LHRH and GRF. Alcohol. 1993 May-Jun; 10(3):185-9.
    View in: PubMed
    Score: 0.001
  30. Emanuele MA, Tentler JJ, Kirsteins L, Emanuele NV, Lawrence A, Kelley MR. The effect of "binge" ethanol exposure on growth hormone and prolactin gene expression and secretion. Endocrinology. 1992 Nov; 131(5):2077-82.
    View in: PubMed
    Score: 0.001
  31. Emanuele MA, Tentler JJ, Halloran MM, Emanuele NV, Wallock L, Kelley MR. The effect of acute in vivo ethanol exposure on follicle stimulating hormone transcription and translation. Alcohol Clin Exp Res. 1992 Aug; 16(4):776-80.
    View in: PubMed
    Score: 0.001
  32. Emanuele NV, Jurgens JK, Halloran MM, Tentler JJ, Lawrence AM, Kelley MR. The rat prolactin gene is expressed in brain tissue: detection of normal and alternatively spliced prolactin messenger RNA. Mol Endocrinol. 1992 Jan; 6(1):35-42.
    View in: PubMed
    Score: 0.001
  33. Emanuele MA, Tentler J, Emanuele NV, Kelley MR. In vivo effects of acute EtOH on rat alpha and beta luteinizing hormone gene expression. Alcohol. 1991 Sep-Oct; 8(5):345-8.
    View in: PubMed
    Score: 0.001
  34. Azad N, Emanuele NV, Halloran MM, Tentler J, Kelley MR. Presence of luteinizing hormone-releasing hormone (LHRH) mRNA in rat spleen lymphocytes. Endocrinology. 1991 Mar; 128(3):1679-81.
    View in: PubMed
    Score: 0.001
  35. Emanuele NV, Emanuele MA, Tentler J, Kirsteins L, Azad N, Lawrence AM. Rat spleen lymphocytes contain an immunoactive and bioactive luteinizing hormone-releasing hormone. Endocrinology. 1990 May; 126(5):2482-6.
    View in: PubMed
    Score: 0.001
  36. Kelley MR, Emanuele MA, Tentler J, Emanuele NV. Cross-reaction of albumin with polyclonal LH antibody on western blots. Endocr Res. 1990; 16(4):477-91.
    View in: PubMed
    Score: 0.001
  37. Emanuele MA, Tentler J, Reda D, Kirsteins L, Emanuele NV, Lawrence AM. The effect of in vitro ethanol exposure on LHRH release from perifused rat hypothalami. Endocr Res. 1990; 16(3):313-21.
    View in: PubMed
    Score: 0.001
  38. Emanuele MA, Tentler J, Reda D, Kirsteins L, Emanuele NV, Lawrence AM. Failure of in vitro ethanol to inhibit LHRH release from the hypothalamus. Alcohol. 1989 Jul-Aug; 6(4):263-6.
    View in: PubMed
    Score: 0.001
  39. Emanuele MA, Tentler J, Reda D, Kirsteins L, Emanuele NV, Lawrence AM. In-vivo effect of ethanol on release of LH-releasing hormone and LH in rats. J Endocrinol. 1989 Apr; 121(1):37-41.
    View in: PubMed
    Score: 0.001
  40. Azad N, Nayyar R, Tentler J, Cernius M, Emanuele NV, Kirsteins L, Lawrence AM. Anatomical and functional effects of estrogen-induced prolactinomas on the rat hypothalamus. J Exp Pathol. 1989; 4(4):237-49.
    View in: PubMed
    Score: 0.001
  41. Emanuele MA, Tentler J, Emanuele NV, Reda D, Kirsteins L, Lawrence AM. In vitro effect of ethanol exposure on basal and GnRH-stimulated LH secretion from pituitary cells. Endocr Res. 1989; 15(3):393-401.
    View in: PubMed
    Score: 0.001
  42. Emanuele MA, Tentler J, Kirsteins L, Reda D, Emanuele NV, Lawrence AM. Anaesthesia with alphaxalone plus alphadolone acetate decreases serum concentrations of LH in castrated rats. J Endocrinol. 1987 Nov; 115(2):221-3.
    View in: PubMed
    Score: 0.001
  43. Emanuele NV, Metcalfe L, Wallock L, Tentler J, Hagen TC, Beer CT, Martinson D, Gout PW, Kirsteins L, Lawrence AM. Extrahypothalamic brain prolactin: characterization and evidence for independence from pituitary prolactin. Brain Res. 1987 Sep 22; 421(1-2):255-62.
    View in: PubMed
    Score: 0.001
  44. Emanuele NV, Metcalfe L, Wallock L, Tentler J, Hagen TC, Beer CT, Martinson D, Gout PW, Kirsteins L, Lawrence AM. Hypothalamic prolactin: characterization by radioimmunoassay and bioassay and response to hypophysectomy and restraint stress. Neuroendocrinology. 1986; 44(2):217-21.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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