 Growth Hormone-Releasing Hormone
"Growth Hormone-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide of 44 amino acids in most species that stimulates the release and synthesis of GROWTH HORMONE. GHRF (or GRF) is synthesized by neurons in the ARCUATE NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, GHRF stimulates GH release by the SOMATOTROPHS in the PITUITARY GLAND.
| Descriptor ID |
D013007
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| MeSH Number(s) |
D06.472.699.327.740.860 D12.644.400.400.740.860 D12.644.548.365.740.860 D12.776.631.650.405.740.860
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| Concept/Terms |
Growth Hormone-Releasing Hormone- Growth Hormone-Releasing Hormone
- Growth Hormone Releasing Hormone
- GRF 1-44
- Growth Hormone-Releasing Factor 44
- Growth Hormone Releasing Factor 44
- Somatotropin-Releasing Factor 44
- Somatotropin Releasing Factor 44
- Somatotropin-Releasing Hormone
- Somatotropin Releasing Hormone
- Growth Hormone-Releasing Factor
- Growth Hormone Releasing Factor
- Somatocrinin
- Somatoliberin
- GHRH 1-44
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Below are MeSH descriptors whose meaning is more general than "Growth Hormone-Releasing Hormone".
Below are MeSH descriptors whose meaning is more specific than "Growth Hormone-Releasing Hormone".
This graph shows the total number of publications written about "Growth Hormone-Releasing Hormone" by people in this website by year, and whether "Growth Hormone-Releasing Hormone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Growth Hormone-Releasing Hormone" by people in Profiles.
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Lake JE, La K, Erlandson KM, Adrian S, Yenokyan G, Scherzinger A, Dub? MP, Stanley T, Grinspoon S, Falutz J, Mamputu JC, Marsolais C, McComsey GA, Brown TT. Tesamorelin improves fat quality independent of changes in fat quantity. AIDS. 2021 07 15; 35(9):1395-1402.
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Adrian S, Scherzinger A, Sanyal A, Lake JE, Falutz J, Dub? MP, Stanley T, Grinspoon S, Mamputu JC, Marsolais C, Brown TT, Erlandson KM. The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV. J Frailty Aging. 2019; 8(3):154-159.
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Burnett LC, LeDuc CA, Sulsona CR, Paull D, Rausch R, Eddiry S, Carli JF, Morabito MV, Skowronski AA, Hubner G, Zimmer M, Wang L, Day R, Levy B, Fennoy I, Dubern B, Poitou C, Clement K, Butler MG, Rosenbaum M, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL. Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome. J Clin Invest. 2017 01 03; 127(1):293-305.
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Siriwardana G, Bradford A, Coy D, Zeitler P. Autocrine/paracrine regulation of breast cancer cell proliferation by growth hormone releasing hormone via Ras, Raf, and mitogen-activated protein kinase. Mol Endocrinol. 2006 Sep; 20(9):2010-9.
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Kapsimalis F, Richardson G, Opp MR, Kryger M. Cytokines and normal sleep. Curr Opin Pulm Med. 2005 Nov; 11(6):481-4.
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Vitiello MV, Moe KE, Merriam GR, Mazzoni G, Buchner DH, Schwartz RS. Growth hormone releasing hormone improves the cognition of healthy older adults. Neurobiol Aging. 2006 Feb; 27(2):318-23.
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Fessler MB, Cool CD, Miller YE, Schwarz MI, Brown KK. Idiopathic diffuse hyperplasia of pulmonary neuroendocrine cells in a patient with acromegaly. Respirology. 2004 Jun; 9(2):274-7.
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Merriam GR, Schwartz RS, Vitiello MV. Growth hormone-releasing hormone and growth hormone secretagogues in normal aging. Endocrine. 2003 Oct; 22(1):41-8.
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Zeitler P, Siriwardana G. Antagonism of endogenous growth hormone-releasing hormone (GHRH) leads to reduced proliferation and apoptosis in MDA231 breast cancer cells. Endocrine. 2002 Jun; 18(1):85-90.
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Zeitler P, Siriwardana G. Stimulation of mitogen-activated protein kinase pathway in rat somatotrophs by growth hormone-releasing hormone. Endocrine. 2000 Jun; 12(3):257-64.
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