 Testosterone
"Testosterone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
| Descriptor ID |
D013739
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| MeSH Number(s) |
D04.210.500.054.079.429.824 D06.472.334.851.968.984
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| Concept/Terms |
Testosterone- Testosterone
- 17-beta-Hydroxy-4-Androsten-3-one
- 17 beta Hydroxy 4 Androsten 3 one
8-Isotestosterone- 8-Isotestosterone
- 8 Isotestosterone
- 17-beta-Hydroxy-8 alpha-4-Androsten-3-one
- 17 beta Hydroxy 8 alpha 4 Androsten 3 one
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Below are MeSH descriptors whose meaning is more general than "Testosterone".
Below are MeSH descriptors whose meaning is more specific than "Testosterone".
This graph shows the total number of publications written about "Testosterone" by people in this website by year, and whether "Testosterone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 1996 | 0 | 2 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 3 | 2 | 5 | | 2002 | 3 | 1 | 4 | | 2003 | 2 | 3 | 5 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 6 | 8 | | 2006 | 2 | 2 | 4 | | 2007 | 3 | 6 | 9 | | 2008 | 5 | 9 | 14 | | 2009 | 5 | 3 | 8 | | 2010 | 9 | 4 | 13 | | 2011 | 3 | 3 | 6 | | 2012 | 6 | 3 | 9 | | 2013 | 9 | 5 | 14 | | 2014 | 15 | 2 | 17 | | 2015 | 8 | 4 | 12 | | 2016 | 8 | 5 | 13 | | 2017 | 8 | 4 | 12 | | 2018 | 7 | 9 | 16 | | 2019 | 8 | 5 | 13 | | 2020 | 9 | 1 | 10 | | 2021 | 5 | 3 | 8 | | 2022 | 4 | 8 | 12 | | 2023 | 2 | 8 | 10 | | 2024 | 3 | 3 | 6 | | 2025 | 3 | 1 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Testosterone" by people in Profiles.
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Hiransuthikul A, Thammajaruk N, Kerr S, Janamnuaysook R, Nonenoy S, Hongchookiat P, Trichavaroj R, Tawon Y, Boonruang J, Teeratakulpisarn N, Cressey TR, Anderson PL, Phanuphak N. Exploring potential drug-drug interactions between masculinizing hormone therapy and oral pre-exposure prophylaxis (F/TDF and F/TAF) among transgender men (iMACT study): a randomized, open-label pharmacokinetic study in Thailand. J Int AIDS Soc. 2025 Apr; 28(4):e26445.
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van Eeghen SA, Pyle L, Narongkiatikhun P, Choi YJ, Obeid W, Parikh CR, Vosters TG, van Valkengoed IG, Krebber MM, Touw DJ, den Heijer M, Bjornstad P, van Raalte DH, Nokoff NJ. Unveiling mechanisms underlying kidney function changes during sex hormone therapy. J Clin Invest. 2025 May 01; 135(9).
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Babcock MC, DuBose LE, Hildreth KL, Stauffer BL, Kohrt WM, Wenner MM, Moreau KL. Endothelial dysfunction in middle-aged and older men with low testosterone is associated with elevated circulating endothelin-1. Am J Physiol Regul Integr Comp Physiol. 2025 Mar 01; 328(3):R253-R261.
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Perng W, Fitz VW, Salmon K, Hivert MF, Kazemi M, Rifas-Shiman SL, Shifren J, Oken E, Chavarro JE. Prevalence and correlates of diagnosed and probable polycystic ovary syndrome (PCOS) in a cohort of parous women. Am J Epidemiol. 2025 Jan 08; 194(1):114-121.
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Nokoff NJ, Nemkov T, Bothwell S, Cree MG, Fuller KNZ, Keller AC, Kelsey MM, Nadeau KJ, Moreau KL. Differences in cardiorespiratory fitness by gonadotropin-releasing hormone agonist treatment before and after testosterone in transgender adolescents. J Appl Physiol (1985). 2024 Nov 01; 137(5):1470-1483.
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Chitrakar A, Bean SM, Kanias T, Thomas KA. Stored platelet hemostatic phenotype and function is not altered when donors are on testosterone replacement therapy. Transfusion. 2024 Aug; 64(8):1520-1532.
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Martin TG, Leinwand LA. Hearts apart: sex differences in cardiac remodeling in health and disease. J Clin Invest. 2024 Jul 01; 134(13).
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Tran J, Jackman RP, Muench MO, Hazegh K, Bean SW, Thomas KA, Fang F, Page G, O'Connor K, Roubinian NH, Anawalt BD, Kanias T. Testosterone supplementation increases red blood cell susceptibility to oxidative stress, decreases membrane deformability, and decreases survival after cold storage and transfusion. Transfusion. 2024 Aug; 64(8):1469-1480.
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Rothman MS, Ariel D, Kelley C, Hamnvik OR, Abramowitz J, Irwig MS, Soe K, Davidge-Pitts C, Misakian AL, Safer JD, Iwamoto SJ. The Use of Injectable Estradiol in Transgender and Gender Diverse Adults: A Scoping Review of Dose and Serum Estradiol Levels. Endocr Pract. 2024 Sep; 30(9):870-878.
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Kim C, Harrall KK, Glueck DH, Hockett C, Dabelea D. Epigenetic age acceleration is associated with speed of pubertal growth but not age of pubertal onset. Sci Rep. 2024 02 05; 14(1):2981.
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