 Testosterone
"Testosterone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
| Descriptor ID |
D013739
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| MeSH Number(s) |
D04.210.500.054.079.429.824 D06.472.334.851.968.984
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| Concept/Terms |
Testosterone- Testosterone
- 17-beta-Hydroxy-4-Androsten-3-one
- 17 beta Hydroxy 4 Androsten 3 one
8-Isotestosterone- 8-Isotestosterone
- 8 Isotestosterone
- 17-beta-Hydroxy-8 alpha-4-Androsten-3-one
- 17 beta Hydroxy 8 alpha 4 Androsten 3 one
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Below are MeSH descriptors whose meaning is more general than "Testosterone".
Below are MeSH descriptors whose meaning is more specific than "Testosterone".
This graph shows the total number of publications written about "Testosterone" by people in this website by year, and whether "Testosterone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 | | 1996 | 0 | 2 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 3 | 2 | 5 | | 2002 | 3 | 1 | 4 | | 2003 | 2 | 3 | 5 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 6 | 8 | | 2006 | 2 | 2 | 4 | | 2007 | 3 | 6 | 9 | | 2008 | 5 | 9 | 14 | | 2009 | 5 | 3 | 8 | | 2010 | 9 | 4 | 13 | | 2011 | 3 | 3 | 6 | | 2012 | 6 | 3 | 9 | | 2013 | 9 | 5 | 14 | | 2014 | 15 | 3 | 18 | | 2015 | 10 | 5 | 15 | | 2016 | 8 | 5 | 13 | | 2017 | 10 | 5 | 15 | | 2018 | 7 | 9 | 16 | | 2019 | 9 | 6 | 15 | | 2020 | 11 | 2 | 13 | | 2021 | 8 | 3 | 11 | | 2022 | 4 | 8 | 12 | | 2023 | 3 | 9 | 12 | | 2024 | 6 | 3 | 9 | | 2025 | 5 | 2 | 7 |
To return to the timeline, click here.
Below are the most recent publications written about "Testosterone" by people in Profiles.
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Grahnemo L, Marriott RJ, Murray K, Tyack LT, Nethander M, Matsumoto AM, Orwoll ES, Vanderschueren D, Yeap BB, Ohlsson C. Associations of Serum Testosterone and SHBG With Incident Fractures in Middle-aged to Older Men. J Clin Endocrinol Metab. 2025 Jun 17; 110(7):1964-1973.
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Spritzer MD, Roy EA, Calhoun KMK, Schneider-Lynch ZE, Panella L, Michaelcheck C, Qian A, Kelly ED, Barr H, Hall E, Cunningham B, Nguyen HHM, Xu D, Barker JM, Galea LAM. Effects of Testosterone and Its Major Metabolites upon Different Stages of Neuron Survival in the Dentate Gyrus of Male Rats. Biomolecules. 2025 Apr 07; 15(4).
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Hiransuthikul A, Thammajaruk N, Kerr S, Janamnuaysook R, Nonenoy S, Hongchookiat P, Trichavaroj R, Tawon Y, Boonruang J, Teeratakulpisarn N, Cressey TR, Anderson PL, Phanuphak N. Exploring potential drug-drug interactions between masculinizing hormone therapy and oral pre-exposure prophylaxis (F/TDF and F/TAF) among transgender men (iMACT study): a randomized, open-label pharmacokinetic study in Thailand. J Int AIDS Soc. 2025 Apr; 28(4):e26445.
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van Eeghen SA, Pyle L, Narongkiatikhun P, Choi YJ, Obeid W, Parikh CR, Vosters TG, van Valkengoed IG, Krebber MM, Touw DJ, den Heijer M, Bjornstad P, van Raalte DH, Nokoff NJ. Unveiling mechanisms underlying kidney function changes during sex hormone therapy. J Clin Invest. 2025 May 01; 135(9).
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Nokoff NJ, Rogol AD. Who may compete in the female category in sport? Chromosomes, genes, hormones, and psychosocial/cultural aspects. Curr Opin Pediatr. 2025 Aug 01; 37(4):398-407.
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Babcock MC, DuBose LE, Hildreth KL, Stauffer BL, Kohrt WM, Wenner MM, Moreau KL. Endothelial dysfunction in middle-aged and older men with low testosterone is associated with elevated circulating endothelin-1. Am J Physiol Regul Integr Comp Physiol. 2025 Mar 01; 328(3):R253-R261.
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Perng W, Fitz VW, Salmon K, Hivert MF, Kazemi M, Rifas-Shiman SL, Shifren J, Oken E, Chavarro JE. Prevalence and correlates of diagnosed and probable polycystic ovary syndrome (PCOS) in a cohort of parous women. Am J Epidemiol. 2025 Jan 08; 194(1):114-121.
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Narinx N, Marriott RJ, Murray K, Adams RJ, Ballantyne CM, Bauer DC, Bhasin S, Biggs ML, Cawthon PM, Couper DJ, Dobs AS, Flicker L, Hankey GJ, Hannemann A, Wilkening R, Martin SA, Matsumoto AM, Ohlsson C, O'Neill TW, Orwoll ES, Shores MM, Steveling A, Travison TG, Wittert GA, Wu FCW, Antonio L, Vanderschueren D, Yeap BB. Sociodemographic, lifestyle, and medical factors associated with calculated free testosterone concentrations in men: individual participant data meta-analyses. Eur J Endocrinol. 2024 Oct 29; 191(5):523-534.
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Nokoff NJ, Nemkov T, Bothwell S, Cree MG, Fuller KNZ, Keller AC, Kelsey MM, Nadeau KJ, Moreau KL. Differences in cardiorespiratory fitness by gonadotropin-releasing hormone agonist treatment before and after testosterone in transgender adolescents. J Appl Physiol (1985). 2024 Nov 01; 137(5):1470-1483.
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DuBose LE, Babcock MC, Kohrt WM, Stauffer BL, Hildreth KL, Walker J, Armstrong MK, Moreau KL. Gonadal status modulates large elastic artery stiffness in healthy middle-aged and older men. Geroscience. 2025 Jun; 47(3):3277-3289.
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