Testosterone
"Testosterone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
| Descriptor ID |
D013739
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| MeSH Number(s) |
D04.210.500.054.079.429.824 D06.472.334.851.968.984
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| Concept/Terms |
Testosterone- Testosterone
- 17-beta-Hydroxy-4-Androsten-3-one
- 17 beta Hydroxy 4 Androsten 3 one
8-Isotestosterone- 8-Isotestosterone
- 8 Isotestosterone
- 17-beta-Hydroxy-8 alpha-4-Androsten-3-one
- 17 beta Hydroxy 8 alpha 4 Androsten 3 one
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Below are MeSH descriptors whose meaning is more general than "Testosterone".
Below are MeSH descriptors whose meaning is more specific than "Testosterone".
This graph shows the total number of publications written about "Testosterone" by people in this website by year, and whether "Testosterone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 3 | 2 | 5 | | 2002 | 3 | 1 | 4 | | 2003 | 2 | 3 | 5 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 6 | 8 | | 2006 | 2 | 2 | 4 | | 2007 | 3 | 6 | 9 | | 2008 | 5 | 9 | 14 | | 2009 | 5 | 3 | 8 | | 2010 | 9 | 3 | 12 | | 2011 | 3 | 3 | 6 | | 2012 | 5 | 3 | 8 | | 2013 | 9 | 5 | 14 | | 2014 | 15 | 4 | 19 | | 2015 | 10 | 5 | 15 | | 2016 | 8 | 5 | 13 | | 2017 | 10 | 5 | 15 | | 2018 | 8 | 9 | 17 | | 2019 | 9 | 6 | 15 | | 2020 | 11 | 2 | 13 | | 2021 | 7 | 3 | 10 | | 2022 | 5 | 8 | 13 | | 2023 | 3 | 9 | 12 | | 2024 | 4 | 3 | 7 | | 2025 | 7 | 2 | 9 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Testosterone" by people in Profiles.
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van Eeghen SA, Pyle L, Narongkiatikhun P, Choi YJ, Vosters TG, van Valkengoed IGM, Bjornstad P, Siegelaar SE, Nokoff NJ, den Heijer M, van Raalte DH. Insulin Sensitivity and Associated Plasma Proteomics During Sex Hormone Therapy. J Clin Endocrinol Metab. 2026 Mar 17; 111(4):e1070-e1079.
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Davis SM, Howell S, Janusz J, Lahlou N, Reynolds R, Thompson T, Swenson K, Wilson R, Ross JL, Zeitler PS, Tartaglia NR. Testosterone Effects on Short-term Physical, Hormonal, and Neurodevelopmental Outcomes (TESTO) in Infants With 47,XXY. J Clin Endocrinol Metab. 2025 Nov 18; 110(12):3493-3504.
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Misakian AL, Ariel D, Sullivan EA, Singh G, Loeb D, Strickland T, Iwamoto SJ, Rothman MS, Botzheim B, Liang JW, Kelley C, Hamnvik OR. Injectable Estradiol Monotherapy Effectively Suppresses Testosterone in Gender-Affirming Hormone Therapy. Endocr Pract. 2025 Nov; 31(11):1462-1469.
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Grahnemo L, Marriott RJ, Murray K, Tyack LT, Nethander M, Matsumoto AM, Orwoll ES, Vanderschueren D, Yeap BB, Ohlsson C. Associations of Serum Testosterone and SHBG With Incident Fractures in Middle-aged to Older Men. J Clin Endocrinol Metab. 2025 Jun 17; 110(7):1964-1973.
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Bennett A, Field J, Newman KL, Click B, Pothula S, Horst S, Davison J, Lin A, Chedid V. Gender-Affirming Hormone Therapy and Risk of Inflammatory Bowel Disease Flare in Transgender and Gender Diverse Adults. Am J Gastroenterol. 2026 Feb 01; 121(2):404-409.
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Spritzer MD, Roy EA, Calhoun KMK, Schneider-Lynch ZE, Panella L, Michaelcheck C, Qian A, Kelly ED, Barr H, Hall E, Cunningham B, Nguyen HHM, Xu D, Barker JM, Galea LAM. Effects of Testosterone and Its Major Metabolites upon Different Stages of Neuron Survival in the Dentate Gyrus of Male Rats. Biomolecules. 2025 04 07; 15(4).
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Hiransuthikul A, Thammajaruk N, Kerr S, Janamnuaysook R, Nonenoy S, Hongchookiat P, Trichavaroj R, Tawon Y, Boonruang J, Teeratakulpisarn N, Cressey TR, Anderson PL, Phanuphak N. Exploring potential drug-drug interactions between masculinizing hormone therapy and oral pre-exposure prophylaxis (F/TDF and F/TAF) among transgender men (iMACT study): a randomized, open-label pharmacokinetic study in Thailand. J Int AIDS Soc. 2025 Apr; 28(4):e26445.
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van Eeghen SA, Pyle L, Narongkiatikhun P, Choi YJ, Obeid W, Parikh CR, Vosters TG, van Valkengoed IG, Krebber MM, Touw DJ, den Heijer M, Bjornstad P, van Raalte DH, Nokoff NJ. Unveiling mechanisms underlying kidney function changes during sex hormone therapy. J Clin Invest. 2025 May 01; 135(9).
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Nokoff NJ, Rogol AD. Who may compete in the female category in sport? Chromosomes, genes, hormones, and psychosocial/cultural aspects. Curr Opin Pediatr. 2025 Aug 01; 37(4):398-407.
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Babcock MC, DuBose LE, Hildreth KL, Stauffer BL, Kohrt WM, Wenner MM, Moreau KL. Endothelial dysfunction in middle-aged and older men with low testosterone is associated with elevated circulating endothelin-1. Am J Physiol Regul Integr Comp Physiol. 2025 Mar 01; 328(3):R253-R261.
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