 Testosterone
"Testosterone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
| Descriptor ID |
D013739
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| MeSH Number(s) |
D04.210.500.054.079.429.824 D06.472.334.851.968.984
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| Concept/Terms |
Testosterone- Testosterone
- 17-beta-Hydroxy-4-Androsten-3-one
- 17 beta Hydroxy 4 Androsten 3 one
8-Isotestosterone- 8-Isotestosterone
- 8 Isotestosterone
- 17-beta-Hydroxy-8 alpha-4-Androsten-3-one
- 17 beta Hydroxy 8 alpha 4 Androsten 3 one
|
Below are MeSH descriptors whose meaning is more general than "Testosterone".
Below are MeSH descriptors whose meaning is more specific than "Testosterone".
This graph shows the total number of publications written about "Testosterone" by people in this website by year, and whether "Testosterone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 3 | 2 | 5 | | 2002 | 3 | 1 | 4 | | 2003 | 2 | 3 | 5 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 6 | 8 | | 2006 | 2 | 2 | 4 | | 2007 | 3 | 6 | 9 | | 2008 | 5 | 8 | 13 | | 2009 | 5 | 3 | 8 | | 2010 | 9 | 3 | 12 | | 2011 | 3 | 3 | 6 | | 2012 | 5 | 3 | 8 | | 2013 | 9 | 5 | 14 | | 2014 | 15 | 5 | 20 | | 2015 | 11 | 5 | 16 | | 2016 | 8 | 5 | 13 | | 2017 | 10 | 5 | 15 | | 2018 | 8 | 9 | 17 | | 2019 | 9 | 6 | 15 | | 2020 | 11 | 2 | 13 | | 2021 | 7 | 3 | 10 | | 2022 | 5 | 8 | 13 | | 2023 | 3 | 9 | 12 | | 2024 | 4 | 3 | 7 | | 2025 | 7 | 2 | 9 | | 2026 | 3 | 3 | 6 |
To return to the timeline, click here.
Below are the most recent publications written about "Testosterone" by people in Profiles.
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Lee J, Chung YM, Silver DJ, Hao Y, Harwood DSL, Ealy A, Serapiglia AM, Curtin L, Benedetti JR, Ballard CAP, Lapsley K, Alvarez-Vazquez A, Goldberg J, Li C, Kaur S, Neal R, Wang SZ, Kay KE, Volovetz J, Hong ES, Fodor R, Jarmula J, Nicosia M, Rubin JB, Swanson KR, Ostrom QT, Panicker N, Kristensen BW, Berens M, Sharifi N, Lathia JD. Androgen loss accelerates brain tumour growth via HPA axis activation. Nature. 2026 May; 653(8116):1184-1195.
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Moolhuijsen LME, Zhu J, Mullin BH, Pujol-Gualdo N, Actkins KV, Mack JA, Rao H, Trivedi B, Kentistou KA, Zhao Y, Westergaard D, Tyrmi JS, Thorleifsson G, Zhang Y, Wittemans L, DeVries A, Brewer K, Sisk R, Danning R, Preuss MH, Jones MR, Ruth KS, Andersen M, Azziz R, Banasik K, Boehnke M, Broer L, Brunak S, Chan YM, Chasman DI, Daly M, Ehrmann DA, Fauser BC, Fritsche LG, Hayes MG, He C, Huang H, Kowalska I, Kraft P, Legro RS, Lin N, Loos RJ, Louwers YV, Magi R, McCarthy MI, Morin-Papunen L, Morrison JV, Morton C, Nadkarni GN, Neale BM, Nielsen HS, Nyegaard M, Ostrowski SR, Pedersen OBV, Sørensen E, Mikkelsen C, Erikstrup C, Kaspersen KA, Bruun MT, Aagaard B, Ullum H, Obermayer-Pietsch B, Palotie A, Reeve MP, Salumets A, Saxena R, Spector TD, Stuckey BGA, Thorsteinsdottir U, Uitterlinden AG, Urbanek M, Zöllner S, van Heel DA, Hirschhorn JN, Stefansson K, Perry JRB, Styrkarsdottir U, Wilson SG, Piltonen T, Laisk T, Jarvelin MR, Burns K, Justice AE, Laivuori H, Ong KK, Goodarzi MO, Davis LK, Dunaif A, Lindgren CM, Laven JSE, Franks S, Visser JA, Welt CK, Karaderi T, Day FR. Genomic analyses implicate hormonal and metabolic dysregulation in polycystic ovary syndrome. Nat Genet. 2026 May; 58(5):1040-1050.
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Nguyen BL, Kehmeier MN, Babcock MC, DuBose LE, Hildreth KL, Stauffer BL, Rosenberry R, Keller AC, Steinke K, Miles K, Guerrero L, Kohrt WM, Reusch J, Clayton ZS, Moreau KL. Endothelial Sirtuins and Mitochondrial Function Are Associated With Testosterone Status: Implications for Accelerated Vascular Aging in Middle-Age and Older Men With Low Testosterone. Aging Cell. 2026 04; 25(4):e70457.
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Melendez Garcia CE, Ahmed UA, Pagan A, Appel A, Nasomyont N, Fiscaletti M, Weber DR, Crane J, Apkon S, Rutter M, Wood C, Ward L, Renthal NE. Caring for Gender Diverse Youth With Duchenne Muscular Dystrophy: A Multisite Case Series. Pediatr Neurol. 2026 Jun; 179:87-90.
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van Eeghen SA, Pyle L, Narongkiatikhun P, Choi YJ, Vosters TG, van Valkengoed IGM, Bjornstad P, Siegelaar SE, Nokoff NJ, den Heijer M, van Raalte DH. Insulin Sensitivity and Associated Plasma Proteomics During Sex Hormone Therapy. J Clin Endocrinol Metab. 2026 Mar 17; 111(4):e1070-e1079.
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John MS, Chinnappan M, Sturges CI, Artami M, Bhattacharya M, Keogh RA, Kavanaugh JS, Jain S, Gedamu H, Komarovsky J, Velasquez M, Sharma T, McDonald JG, Horswill AR, Harris-Tryon TA. Skin androgens regulate Staphylococcus aureus pathogenicity via quorum sensing. Nat Microbiol. 2026 Mar; 11(3):704-717.
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Davis SM, Howell S, Janusz J, Lahlou N, Reynolds R, Thompson T, Swenson K, Wilson R, Ross JL, Zeitler PS, Tartaglia NR. Testosterone Effects on Short-term Physical, Hormonal, and Neurodevelopmental Outcomes (TESTO) in Infants With 47,XXY. J Clin Endocrinol Metab. 2025 Nov 18; 110(12):3493-3504.
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Misakian AL, Ariel D, Sullivan EA, Singh G, Loeb D, Strickland T, Iwamoto SJ, Rothman MS, Botzheim B, Liang JW, Kelley C, Hamnvik OR. Injectable Estradiol Monotherapy Effectively Suppresses Testosterone in Gender-Affirming Hormone Therapy. Endocr Pract. 2025 Nov; 31(11):1462-1469.
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Grahnemo L, Marriott RJ, Murray K, Tyack LT, Nethander M, Matsumoto AM, Orwoll ES, Vanderschueren D, Yeap BB, Ohlsson C. Associations of Serum Testosterone and SHBG With Incident Fractures in Middle-aged to Older Men. J Clin Endocrinol Metab. 2025 Jun 17; 110(7):1964-1973.
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Bennett A, Field J, Newman KL, Click B, Pothula S, Horst S, Davison J, Lin A, Chedid V. Gender-Affirming Hormone Therapy and Risk of Inflammatory Bowel Disease Flare in Transgender and Gender Diverse Adults. Am J Gastroenterol. 2026 Feb 01; 121(2):404-409.
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