 Ketamine
"Ketamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
| Descriptor ID |
D007649
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| MeSH Number(s) |
D02.455.426.392.368.367.652
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| Concept/Terms |
Ketamine- Ketamine
- 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
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Below are MeSH descriptors whose meaning is more general than "Ketamine".
Below are MeSH descriptors whose meaning is more specific than "Ketamine".
This graph shows the total number of publications written about "Ketamine" by people in this website by year, and whether "Ketamine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 1 | 2 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 2 | 0 | 2 | | 2011 | 2 | 1 | 3 | | 2012 | 1 | 0 | 1 | | 2014 | 0 | 2 | 2 | | 2015 | 5 | 0 | 5 | | 2016 | 6 | 2 | 8 | | 2017 | 2 | 2 | 4 | | 2018 | 4 | 3 | 7 | | 2019 | 3 | 2 | 5 | | 2020 | 3 | 0 | 3 | | 2021 | 0 | 1 | 1 | | 2022 | 4 | 0 | 4 | | 2023 | 5 | 1 | 6 |
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Below are the most recent publications written about "Ketamine" by people in Profiles.
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Niciu MJ, Meisner RC, Carr BR, Farooqui AA, Feifel D, Kaplin A, Kendrick EJ, Kim PM, Schneck CD, Vande Voort JL, Parikh SV. National Network of Depression Centers position statement: Insurance coverage for intravenous ketamine in treatment-resistant major depressive disorder. J Affect Disord. 2024 02 01; 346:221-222.
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Song R, Zhang J, Perszyk RE, Camp CR, Tang W, Kannan V, Li J, Xu Y, Chen J, Li Y, Liang SH, Traynelis SF, Yuan H. Differential responses of disease-related GRIN variants located in pore-forming M2 domain of N-methyl-D-aspartate receptor to FDA-approved inhibitors. J Neurochem. 2024 Dec; 168(12):3936-3949.
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Driver BE, Trent SA, Prekker ME, Reardon RF, Brown CA. Sedative Dose for Rapid Sequence Intubation and Postintubation Hypotension: Is There an Association? Ann Emerg Med. 2023 10; 82(4):417-424.
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Freedman R. Ketamine and ECT in Depression - Risks and Rewards. N Engl J Med. 2023 Jun 22; 388(25):2389-2390.
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Hudson IL, Staudt AM, Burgess M, Hinojosa-Laborde C, Schauer SG, Newberry RK, Ryan KL, VanFosson CA. Patterns of Palliation: A Review of Casualties That Received Pain Management Before Reaching Role 2 in Afghanistan. Mil Med. 2023 01 04; 188(1-2):108-116.
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Zanos P, Brown KA, Georgiou P, Yuan P, Zarate CA, Thompson SM, Gould TD. NMDA Receptor Activation-Dependent Antidepressant-Relevant Behavioral and Synaptic Actions of Ketamine. J Neurosci. 2023 02 08; 43(6):1038-1050.
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Lockett C, Naylor JF, Fisher AD, Long BJ, April MD, Schauer SG. A Comparison of Injury Patterns and Interventions among US Military Special Operations Versus Conventional Forces Combatants. Med J (Ft Sam Houst Tex). 2023 Jan-Mar; (Per 23-1/2/3):64-69.
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Terasaki D, Loh R, Cornell A, Taub J, Thurstone C. Single-dose intravenous ketamine or intramuscular naltrexone for high-utilization inpatients with alcohol use disorder: pilot trial feasibility and readmission rates. Addict Sci Clin Pract. 2022 11 22; 17(1):64.
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Bell CM, Rech MA, Akuamoah-Boateng KA, Kasotakis G, McMurray JD, Moses BA, Mueller SW, Patel GP, Roberts RJ, Sakhuja A, Salvator A, Setliff EL, Droege CA. Ketamine in Critically Ill Patients: Use, Perceptions, and Potential Barriers. J Pharm Pract. 2024 Apr; 37(2):351-363.
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Georgiou P, Zanos P, Mou TM, An X, Gerhard DM, Dryanovski DI, Potter LE, Highland JN, Jenne CE, Stewart BW, Pultorak KJ, Yuan P, Powels CF, Lovett J, Pereira EFR, Clark SM, Tonelli LH, Moaddel R, Zarate CA, Duman RS, Thompson SM, Gould TD. Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor. Nat Neurosci. 2022 09; 25(9):1191-1200.
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