 Transcription Factor Pit-1
"Transcription Factor Pit-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A POU domain factor that regulates expression of GROWTH HORMONE; PROLACTIN; and THYROTROPIN-BETA in the ANTERIOR PITUITARY GLAND.
| Descriptor ID |
D050817
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| MeSH Number(s) |
D12.776.260.655.750 D12.776.930.710.750
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| Concept/Terms |
Transcription Factor Pit-1- Transcription Factor Pit-1
- Pit-1, Transcription Factor
- Transcription Factor Pit 1
- GHF1 Protein
- Pit-1 Transcription Factor
- Pit 1 Transcription Factor
- Transcription Factor, Pit-1
- Pituitary-Specific Transcription Factor Pit-1
- Pituitary Specific Transcription Factor Pit 1
- Transcription Factor GHF-1
- GHF-1, Transcription Factor
- Transcription Factor GHF 1
- GHF-1 Transcription Factor
- GHF 1 Transcription Factor
- Transcription Factor, GHF-1
- Pit1 Growth Hormone Factor
Transcription Factor Pit-2- Transcription Factor Pit-2
- Pit-2, Transcription Factor
- Transcription Factor Pit 2
- Pit-2 Protein
- Pit 2 Protein
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor Pit-1".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor Pit-1".
This graph shows the total number of publications written about "Transcription Factor Pit-1" by people in this website by year, and whether "Transcription Factor Pit-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 0 | 4 | 4 | | 1997 | 0 | 3 | 3 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factor Pit-1" by people in Profiles.
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Tong Y, Zhou J, Mizutani J, Fukuoka H, Ren SG, Gutierrez-Hartmann A, Koeffler HP, Melmed S. CEBPD suppresses prolactin expression and prolactinoma cell proliferation. Mol Endocrinol. 2011 Nov; 25(11):1880-91.
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Mortensen AH, MacDonald JW, Ghosh D, Camper SA. Candidate genes for panhypopituitarism identified by gene expression profiling. Physiol Genomics. 2011 Oct 06; 43(19):1105-16.
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Zhang Z, Florez S, Gutierrez-Hartmann A, Martin JF, Amendt BA. MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression. J Biol Chem. 2010 Nov 05; 285(45):34718-28.
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Jean A, Gutierrez-Hartmann A, Duval DL. A Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit Ras and estrogen stimulation of the prolactin gene promoter. Mol Endocrinol. 2010 Jan; 24(1):91-103.
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Jonsen MD, Duval DL, Gutierrez-Hartmann A. The 26-amino acid beta-motif of the Pit-1beta transcription factor is a dominant and independent repressor domain. Mol Endocrinol. 2009 Sep; 23(9):1371-84.
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Kerr J, Wood W, Ridgway EC. Basic science and clinical research advances in the pituitary transcription factors: Pit-1 and Prop-1. Curr Opin Endocrinol Diabetes Obes. 2008 Aug; 15(4):359-63.
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Wang CC, Sorribas V, Sharma G, Levi M, Draznin B. Insulin attenuates vascular smooth muscle calcification but increases vascular smooth muscle cell phosphate transport. Atherosclerosis. 2007 Nov; 195(1):e65-75.
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Duval DL, Jonsen MD, Diamond SE, Murapa P, Jean A, Gutierrez-Hartmann A. Differential utilization of transcription activation subdomains by distinct coactivators regulates Pit-1 basal and Ras responsiveness. Mol Endocrinol. 2007 Jan; 21(1):172-85.
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Ferry AL, Locasto DM, Meszaros LB, Bailey JC, Jonsen MD, Brodsky K, Hoon CJ, Gutierrez-Hartmann A, Diamond SE. Pit-1beta reduces transcription and CREB-binding protein recruitment in a DNA context-dependent manner. J Endocrinol. 2005 Apr; 185(1):173-85.
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Duval DL, Jean A, Gutierrez-Hartmann A. Ras signaling and transcriptional synergy at a flexible Ets-1/Pit-1 composite DNA element is defined by the assembly of selective activation domains. J Biol Chem. 2003 Oct 10; 278(41):39684-96.
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