 Gene Rearrangement
"Gene Rearrangement" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ordered rearrangement of gene regions by DNA recombination such as that which occurs normally during development.
| Descriptor ID |
D015321
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| MeSH Number(s) |
G05.344
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| Concept/Terms |
Gene Rearrangement- Gene Rearrangement
- Gene Rearrangements
- Rearrangement, Gene
- Rearrangements, Gene
- DNA Rearrangement
- DNA Rearrangements
- Rearrangement, DNA
- Rearrangements, DNA
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Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement".
This graph shows the total number of publications written about "Gene Rearrangement" by people in this website by year, and whether "Gene Rearrangement" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2002 | 1 | 2 | 3 | | 2004 | 1 | 3 | 4 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 1 | 2 | 3 | | 2011 | 2 | 1 | 3 | | 2012 | 1 | 3 | 4 | | 2013 | 4 | 2 | 6 | | 2014 | 1 | 2 | 3 | | 2015 | 5 | 5 | 10 | | 2016 | 3 | 4 | 7 | | 2017 | 3 | 3 | 6 | | 2018 | 4 | 5 | 9 | | 2019 | 2 | 3 | 5 | | 2020 | 1 | 1 | 2 | | 2021 | 1 | 4 | 5 | | 2022 | 0 | 3 | 3 | | 2024 | 3 | 3 | 6 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Gene Rearrangement" by people in Profiles.
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Davies KD. Finding Rearrangements in the Cell-Free DNA Haystack. Clin Cancer Res. 2025 Jun 13; 31(12):2264-2266.
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Galbraith K, Wu J, Sikkink K, Mohamed H, Reid D, Perez-Arreola M, Belton JM, Nomikou S, Melnyk S, Yang Y, Liechty BL, Jour G, Tsirigos A, Hermel DJ, Beck A, Sigal D, Dahl NA, Vibhakar R, Schmitt A, Snuderl M. Detection of Gene Fusions and Rearrangements in Formalin-Fixed, Paraffin-Embedded Solid Tumor Specimens Using High-Throughput Chromosome Conformation Capture. J Mol Diagn. 2025 May; 27(5):346-359.
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Balestra T, Niswander LM, Bagashev A, Loftus JP, Ross SL, Chen RK, McClellan SM, Junco JJ, B?rcenas L?pez DA, Rabin KR, Fry TJ, Tasian SK. Co-targeting of the thymic stromal lymphopoietin receptor to decrease immunotherapeutic resistance in CRLF2-rearranged Ph-like and Down syndrome acute lymphoblastic leukemia. Leukemia. 2025 Mar; 39(3):555-567.
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Guest EM, Kairalla JA, Devidas M, Hibbitts E, Carroll AJ, Heerema NA, Kubaney HR, August MA, Ramesh S, Yoo B, Farooqi MS, Pauly MG, Wechsler DS, Miles RR, Reid JM, Kihei CD, Gore L, Raetz EA, Hunger SP, Loh ML, Brown PA. Azacitidine as epigenetic priming for chemotherapy is safe and well-tolerated in infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia: Children's Oncology Group trial AALL15P1. Haematologica. 2024 Dec 01; 109(12):3918-3927.
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Lee JC, Koo SC, Furtado LV, Breuer A, Eldomery MK, Bag AK, Stow P, Rose G, Larkin T, Sances R, Kleinschmidt-DeMasters BK, Bodmer JL, Willard N, Gokden M, Dahiya S, Roberts K, Bertrand KC, Moreira DC, Robinson GW, Mo JQ, Ellison DW, Orr BA. Concurrent ependymal and ganglionic differentiation in a subset of supratentorial neuroepithelial tumors with EWSR1-PLAGL1 rearrangement. Acta Neuropathol Commun. 2024 Sep 03; 12(1):143.
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Johnson M, Willard N, Pan Z. Systemic ALK-negative anaplastic large cell lymphoma with NPM1::TYK2 rearrangement. J Hematop. 2024 Dec; 17(4):265-270.
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Issa GC, Aldoss I, Thirman MJ, DiPersio J, Arellano M, Blachly JS, Mannis GN, Perl A, Dickens DS, McMahon CM, Traer E, Zwaan CM, Grove CS, Stone R, Shami PJ, Mantzaris I, Greenwood M, Shukla N, Cuglievan B, Kovacsovics T, Gu Y, Bagley RG, Madigan K, Chudnovsky Y, Nguyen HV, McNeer N, Stein EM. Menin Inhibition With Revumenib for KMT2A-Rearranged Relapsed or Refractory Acute Leukemia (AUGMENT-101). J Clin Oncol. 2025 Jan; 43(1):75-84.
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Murphy L, Siegele B, Carstens B, Hartman L, Faulk K. A pediatric case of KMT2A-rearranged B-lymphoblastic lymphoma treated with high-risk therapy. Leuk Lymphoma. 2024 Jun; 65(6):843-847.
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Rankin AW, Siegele B, Gross TG. Discordance between detection of MYC rearrangement by immunohistochemistry versus fluorescent in situ hybridization in Burkitt lymphoma. Pediatr Blood Cancer. 2022 12; 69(12):e29804.
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Ng TL, Tsui DCC, Wang S, Usari T, Patil T, Wilner K, Camidge DR. Association of anticoagulant use with clinical outcomes from crizotinib in ALK- and ROS1-rearranged advanced non-small cell lung cancers: A retrospective analysis of PROFILE 1001. Cancer Med. 2022 Dec; 11(23):4422-4429.
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