 Ubiquitin-Protein Ligases
"Ubiquitin-Protein Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.
| Descriptor ID |
D044767
|
| MeSH Number(s) |
D08.811.464.938.750
|
| Concept/Terms |
Ubiquitin-Protein Ligases- Ubiquitin-Protein Ligases
- Ligases, Ubiquitin-Protein
- Ubiquitin Protein Ligases
- E3 Ubiquitin Ligase
- Ligase, E3 Ubiquitin
- Ubiquitin Ligase, E3
- Ubiquitin-Protein Ligase E3
- Ligase E3, Ubiquitin-Protein
- Ubiquitin Protein Ligase E3
- Ubiquitin Ligase E3
- Ligase E3, Ubiquitin
- Ubiquitin-Protein Ligase
- Ligase, Ubiquitin-Protein
- Ubiquitin Protein Ligase
- E3 Ligase
- Ligase, E3
|
Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Protein Ligases".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Protein Ligases".
This graph shows the total number of publications written about "Ubiquitin-Protein Ligases" by people in this website by year, and whether "Ubiquitin-Protein Ligases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 | | 1999 | 1 | 0 | 1 | | 2000 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 2 | 2 | | 2005 | 1 | 3 | 4 | | 2006 | 1 | 4 | 5 | | 2007 | 2 | 3 | 5 | | 2008 | 5 | 0 | 5 | | 2009 | 1 | 5 | 6 | | 2010 | 1 | 3 | 4 | | 2011 | 1 | 2 | 3 | | 2012 | 5 | 2 | 7 | | 2013 | 3 | 7 | 10 | | 2014 | 6 | 5 | 11 | | 2015 | 7 | 3 | 10 | | 2016 | 5 | 2 | 7 | | 2017 | 7 | 5 | 12 | | 2018 | 1 | 2 | 3 | | 2019 | 3 | 4 | 7 | | 2020 | 11 | 2 | 13 | | 2021 | 5 | 4 | 9 | | 2022 | 2 | 3 | 5 | | 2023 | 2 | 3 | 5 | | 2024 | 5 | 5 | 10 | | 2025 | 3 | 5 | 8 | | 2026 | 2 | 4 | 6 |
To return to the timeline, click here.
Below are the most recent publications written about "Ubiquitin-Protein Ligases" by people in Profiles.
-
Yao T, Kutateladze TG. Photoreactive crosslinkers capture the ubiquitin-E2-E3 ligases intermediates. Biochem J. 2026 Sep 02; 483(9):1709-1711.
-
Dholakia GL, Stemm-Wolf AJ, Anzar A, Turkewitz AP, Pearson CG. Tet Trim-Away: a conditional rapid protein degradation system for Tetrahymena thermophila. Mol Biol Cell. 2026 Sep; 37(9):mr9.
-
Wettstein R, King GA, Henggeler A, Walsh ME, Ruediger CT, Ünal E, Matos J. Synaptonemal complex SUMOylation is maintained by Nup60-dependent docking of Ulp1 at the nuclear periphery. Cell Rep. 2026 Jun 23; 45(6):117539.
-
Orr L, Golding H, O'Brien E, Siauw J, Su TT. Pink1 represses apoptosis and allows proper morphogenesis after exposure to ionizing radiation in Drosophila melanogaster. Genetics. 2026 05 06; 233(1).
-
Zhu W, Pan L, Cui X, Russo AC, Ray R, Pederson B, Wei X, Lin LL, Torres M, Hafner H, Gregg B, Shrestha N, Liu C, Naji A, Arvan P, Sandoval DA, Lindberg I, Qi L, Reinert RB. SEL1L-HRD1 ER-associated degradation facilitates prohormone convertase 2 maturation and glucagon production in islet a cells. Nat Commun. 2026 Feb 25; 17(1).
-
Nebenfuehr B, Sanford L, Taylor ER, Ball K, Woods-Killam CE, Ghasemi HI, Proctor B, Ortega R, Sempeck C, Dowell RD, Arnoult N. Uncovering genetic interactions in the DNA repair network in response to endogenous damage and ionizing radiation. Cell Rep. 2026 Jan 27; 45(1):116850.
-
Roberts JE, Huynh PT, Carale LO, Whiteley AM. UBQLN2 is necessary for UBE3A-mediated proteasomal degradation of the domesticated retroelement PEG10. J Cell Sci. 2025 12 15; 138(24).
-
Thorne AJ, Gao A, Necker-Brown A, Bansal A, Kalyanaraman K, Chandramohan P, Sasse SK, Gerber AN, Mostafa MM, Newton R. Differential RELA and GR recruitment to the BIRC3/BIRC2 locus: Molecular insight as to combinatorial regulation by proinflammatory cytokines and glucocorticoid. Mol Pharmacol. 2025 10; 107(10):100073.
-
Livingston PD, Labbate Bonaldo AL, Jamnick NA, Weinzierl NM, Gammon CJ, Callaway CS, Lee S, Gao B, Goodspeed A, Carvalho RF, Young CD, Orlicky DJ, Adams DJ, Novinger LJ, Bonetto A. B0092 tumor-bearing mice are a new model for the study of cachexia in head and neck cancer. Am J Physiol Cell Physiol. 2025 08 01; 329(2):C646-C658.
-
Patel R, Fountzilas C, Horowitz M, Schultz E, Clayback KM, Knudsen ES, Witkiewicz AK, Onel K. Pancreatic adenocarcinoma in a patient with a germline RB1 pathogenic variant. Fam Cancer. 2025 05 26; 24(2):46.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|