 Ubiquitin-Protein Ligases
"Ubiquitin-Protein Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.
| Descriptor ID |
D044767
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| MeSH Number(s) |
D08.811.464.938.750
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| Concept/Terms |
Ubiquitin-Protein Ligases- Ubiquitin-Protein Ligases
- Ligases, Ubiquitin-Protein
- Ubiquitin Protein Ligases
- E3 Ubiquitin Ligase
- Ligase, E3 Ubiquitin
- Ubiquitin Ligase, E3
- Ubiquitin-Protein Ligase E3
- Ligase E3, Ubiquitin-Protein
- Ubiquitin Protein Ligase E3
- Ubiquitin Ligase E3
- Ligase E3, Ubiquitin
- Ubiquitin-Protein Ligase
- Ligase, Ubiquitin-Protein
- Ubiquitin Protein Ligase
- E3 Ligase
- Ligase, E3
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Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Protein Ligases".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Protein Ligases".
This graph shows the total number of publications written about "Ubiquitin-Protein Ligases" by people in this website by year, and whether "Ubiquitin-Protein Ligases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 4 | 4 | | 2006 | 1 | 4 | 5 | | 2007 | 2 | 4 | 6 | | 2008 | 5 | 0 | 5 | | 2009 | 1 | 5 | 6 | | 2010 | 1 | 2 | 3 | | 2011 | 1 | 3 | 4 | | 2012 | 5 | 1 | 6 | | 2013 | 3 | 7 | 10 | | 2014 | 6 | 4 | 10 | | 2015 | 6 | 2 | 8 | | 2016 | 5 | 1 | 6 | | 2017 | 6 | 5 | 11 | | 2018 | 1 | 1 | 2 | | 2019 | 2 | 4 | 6 | | 2020 | 7 | 1 | 8 | | 2021 | 1 | 2 | 3 | | 2022 | 1 | 2 | 3 | | 2023 | 2 | 2 | 4 |
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Below are the most recent publications written about "Ubiquitin-Protein Ligases" by people in Profiles.
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Tencer AH, Yu Y, Causse SZ, Campbell GR, Klein BJ, Xuan H, Cartier J, Miles MA, Gaurav N, Zadoroznyj A, Holt TA, Wen H, Hawkins CJ, Spector SA, Dubrez L, Shi X, Kutateladze TG. Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2. Nat Struct Mol Biol. 2023 09; 30(9):1265-1274.
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Mlera L, Collins-McMillen D, Zeltzer S, Buehler JC, Moy M, Zarrella K, Caviness K, Cicchini L, Tafoya DJ, Goodrum F. Liver X Receptor-Inducible Host E3 Ligase IDOL Targets a Human Cytomegalovirus Reactivation Determinant. J Virol. 2023 07 27; 97(7):e0075823.
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Yeon M, Bertolini I, Agarwal E, Ghosh JC, Tang HY, Speicher DW, Keeney F, Sossey-Alaoui K, Pluskota E, Bialkowska K, Plow EF, Languino LR, Skordalakes E, Caino MC, Altieri DC. Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression. J Biol Chem. 2023 06; 299(6):104774.
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Alula KM, Delgado-Deida Y, Callahan R, Till A, Underwood L, Thompson WE, Souza RF, Dassopoulos T, Onyiah J, Venuprasad K, Theiss AL. Inner mitochondrial membrane protein Prohibitin 1 mediates Nix-induced, Parkin-independent mitophagy. Sci Rep. 2023 01 02; 13(1):18.
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Tencer AH, Liu J, Zhu J, Burkholder NT, Zhang Y, Wu W, Strahl BD, Ohta T, Kutateladze TG. The ZZ domain of HERC2 is a receptor of arginylated substrates. Sci Rep. 2022 04 11; 12(1):6063.
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Duncan ED, Han KJ, Trout MA, Prekeris R. Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration. J Cell Biol. 2022 04 04; 221(4).
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Schriek P, Ching AC, Moily NS, Moffat J, Beattie L, Steiner TM, Hosking LM, Thurman JM, Holers VM, Ishido S, Lahoud MH, Caminschi I, Heath WR, Mintern JD, Villadangos JA. Marginal zone B cells acquire dendritic cell functions by trogocytosis. Science. 2022 02 11; 375(6581):eabf7470.
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Ramirez A, Old W, Selwood DL, Liu X. Cannabidiol activates PINK1-Parkin-dependent mitophagy and mitochondrial-derived vesicles. Eur J Cell Biol. 2022 Jan; 101(1):151185.
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Markati T, Duis J, Servais L. Therapies in preclinical and clinical development for Angelman syndrome. Expert Opin Investig Drugs. 2021 Jul; 30(7):709-720.
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Mills CA, Wang X, Bhatt DP, Grimsrud PA, Matson JP, Lahiri D, Burke DJ, Cook JG, Hirschey MD, Emanuele MJ. Sirtuin 5 Is Regulated by the SCFCyclin F Ubiquitin Ligase and Is Involved in Cell Cycle Control. Mol Cell Biol. 2021 01 25; 41(2).
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