Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Arcaroli

Concepts (368)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
19
2018
803
2.480
Why?
Xenograft Model Antitumor Assays
21
2024
865
1.460
Why?
Antineoplastic Agents
17
2018
2158
1.330
Why?
Drug Resistance, Neoplasm
7
2016
801
1.030
Why?
Benzodioxoles
3
2012
116
1.000
Why?
Quinazolines
4
2012
249
1.000
Why?
Camptothecin
4
2016
121
0.880
Why?
Receptor, Notch1
3
2015
64
0.850
Why?
Aldehyde Dehydrogenase
6
2017
100
0.850
Why?
Mice, Nude
16
2024
688
0.790
Why?
Haplotypes
4
2012
494
0.740
Why?
Phosphatidylinositol 3-Kinases
10
2018
369
0.700
Why?
Gene Dosage
3
2015
142
0.630
Why?
Wnt Signaling Pathway
5
2024
196
0.620
Why?
Neutrophils
13
2007
1273
0.600
Why?
src-Family Kinases
3
2017
93
0.590
Why?
Amyloid Precursor Protein Secretases
3
2014
79
0.580
Why?
Pancreatic Neoplasms
6
2024
856
0.580
Why?
Endotoxemia
9
2004
86
0.570
Why?
Anilides
2
2018
72
0.570
Why?
Enzyme Inhibitors
5
2016
849
0.560
Why?
Protein Kinase Inhibitors
9
2018
914
0.560
Why?
Biomarkers, Tumor
9
2018
1237
0.540
Why?
Mice
41
2024
17761
0.520
Why?
Acute Lung Injury
2
2011
286
0.520
Why?
Pyridines
4
2018
499
0.510
Why?
Receptors, Notch
2
2015
87
0.500
Why?
Tankyrases
1
2016
13
0.500
Why?
Cell Line, Tumor
21
2024
3403
0.490
Why?
Drug Discovery
1
2016
145
0.470
Why?
Polymorphism, Genetic
3
2007
634
0.460
Why?
NF-kappa B
13
2007
679
0.460
Why?
3' Untranslated Regions
2
2012
145
0.450
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2014
86
0.440
Why?
DNA Copy Number Variations
1
2015
178
0.440
Why?
Proto-Oncogene Proteins c-met
1
2014
73
0.430
Why?
Tetrahydronaphthalenes
1
2013
30
0.410
Why?
Valine
1
2013
79
0.400
Why?
Animals
44
2024
37129
0.390
Why?
Mitogen-Activated Protein Kinases
7
2014
315
0.380
Why?
Sepsis
3
2007
603
0.350
Why?
Lipopolysaccharides
9
2007
883
0.350
Why?
Signal Transduction
17
2018
5065
0.350
Why?
Proto-Oncogene Proteins
8
2018
623
0.330
Why?
Superoxide Dismutase
3
2008
352
0.330
Why?
Urokinase-Type Plasminogen Activator
2
2007
29
0.330
Why?
Cell Proliferation
13
2024
2470
0.320
Why?
Interleukins
1
2011
251
0.310
Why?
Hemorrhage
6
2004
720
0.310
Why?
Neoplasm Metastasis
4
2016
673
0.310
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
98
0.290
Why?
Heterografts
3
2018
134
0.290
Why?
HCT116 Cells
4
2018
80
0.280
Why?
Apoptosis
11
2018
2556
0.270
Why?
SOXB1 Transcription Factors
2
2018
62
0.260
Why?
Carcinoma, Pancreatic Ductal
2
2024
266
0.260
Why?
Azepines
2
2018
97
0.260
Why?
Promoter Regions, Genetic
1
2011
1237
0.250
Why?
Benzimidazoles
3
2013
174
0.250
Why?
Mutation
3
2012
3993
0.250
Why?
Immunoblotting
5
2015
306
0.250
Why?
Receptors, Interleukin-1
1
2006
215
0.230
Why?
Neutrophil Activation
5
2003
84
0.230
Why?
beta Catenin
3
2016
252
0.230
Why?
Humans
46
2024
138201
0.220
Why?
Oligonucleotide Array Sequence Analysis
6
2015
759
0.220
Why?
TOR Serine-Threonine Kinases
4
2018
417
0.220
Why?
Pyrimidines
2
2018
475
0.210
Why?
Intracellular Signaling Peptides and Proteins
2
2006
462
0.210
Why?
Mice, Inbred BALB C
10
2003
1260
0.200
Why?
Adrenergic alpha-Antagonists
2
2002
34
0.200
Why?
Proto-Oncogene Proteins c-akt
8
2018
442
0.200
Why?
Colonic Neoplasms
2
2016
251
0.200
Why?
Proto-Oncogene Proteins c-raf
1
2002
44
0.190
Why?
Adrenergic alpha-Agonists
1
2002
28
0.190
Why?
Genetic Predisposition to Disease
1
2011
2368
0.190
Why?
Female
24
2018
73713
0.190
Why?
Neuroimmunomodulation
1
2002
65
0.190
Why?
ras Proteins
3
2013
149
0.190
Why?
Aged
11
2016
24134
0.190
Why?
Adrenergic beta-Agonists
1
2002
97
0.190
Why?
Adrenergic beta-Antagonists
2
2002
227
0.180
Why?
Middle Aged
12
2016
33711
0.180
Why?
Hemoptysis
1
2000
36
0.170
Why?
Polymorphism, Single Nucleotide
4
2011
2143
0.160
Why?
In Situ Hybridization, Fluorescence
2
2012
309
0.160
Why?
Head and Neck Neoplasms
2
2016
553
0.160
Why?
Cytokines
4
2005
2080
0.160
Why?
Carcinoma, Squamous Cell
2
2016
646
0.160
Why?
Adult
11
2016
38190
0.160
Why?
Male
24
2016
68035
0.150
Why?
Cell Transformation, Neoplastic
2
2018
333
0.150
Why?
DNA Topoisomerases, Type II
2
2016
45
0.150
Why?
Transplantation, Heterologous
2
2016
194
0.150
Why?
CDC2 Protein Kinase
1
2018
32
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
71
0.140
Why?
Oncogene Proteins v-abl
1
2017
5
0.140
Why?
Cyclic AMP Response Element-Binding Protein
4
2003
145
0.140
Why?
Mitogen-Activated Protein Kinase Kinases
3
2010
132
0.140
Why?
p38 Mitogen-Activated Protein Kinases
6
2007
279
0.140
Why?
Dasatinib
1
2017
56
0.140
Why?
Proto-Oncogene Proteins p21(ras)
5
2016
263
0.130
Why?
Immunohistochemistry
5
2017
1727
0.130
Why?
Gene Expression Profiling
4
2018
1754
0.130
Why?
Case-Control Studies
3
2011
3574
0.130
Why?
Angiogenesis Inhibitors
2
2018
230
0.130
Why?
Neovascularization, Pathologic
2
2018
296
0.130
Why?
Intercellular Signaling Peptides and Proteins
2
2015
384
0.130
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.130
Why?
Adenocarcinoma
2
2014
883
0.130
Why?
Receptors, Cell Surface
2
2012
392
0.130
Why?
Axin Protein
1
2016
19
0.130
Why?
Corynebacterium
1
2017
49
0.130
Why?
Aurora Kinase A
1
2016
57
0.130
Why?
Corynebacterium Infections
1
2017
42
0.120
Why?
Antigens, Neoplasm
2
2016
317
0.120
Why?
Neoplasms, Experimental
1
2017
174
0.120
Why?
Transcription Factor 7-Like 2 Protein
1
2016
26
0.120
Why?
Cell Cycle
5
2018
598
0.120
Why?
Neoplastic Stem Cells
2
2018
398
0.120
Why?
Autophagy
1
2018
286
0.120
Why?
Serrate-Jagged Proteins
1
2015
27
0.120
Why?
Jagged-1 Protein
1
2015
23
0.120
Why?
Genotype
3
2012
1873
0.120
Why?
RNA, Messenger
5
2016
2808
0.120
Why?
RNA, Small Interfering
2
2015
621
0.120
Why?
Neoplasms
3
2016
2694
0.120
Why?
Aged, 80 and over
5
2014
7683
0.120
Why?
Drug Synergism
2
2014
369
0.120
Why?
Gene Duplication
1
2015
67
0.120
Why?
Retinaldehyde
1
2015
4
0.120
Why?
HMGB1 Protein
2
2007
51
0.110
Why?
Pyrazoles
1
2018
428
0.110
Why?
Acetaldehyde
1
2015
17
0.110
Why?
Pyrimidinones
1
2015
111
0.110
Why?
Chemokines
5
2003
227
0.110
Why?
Acridines
1
2014
7
0.110
Why?
Neoplasm Transplantation
4
2016
250
0.110
Why?
Chemokine CXCL2
4
2001
42
0.110
Why?
Antineoplastic Combined Chemotherapy Protocols
3
2014
1755
0.110
Why?
Topoisomerase II Inhibitors
1
2014
26
0.110
Why?
Respiration, Artificial
2
2011
642
0.110
Why?
Benzazepines
1
2014
36
0.110
Why?
Wnt Proteins
1
2015
135
0.110
Why?
Pyridones
1
2015
169
0.110
Why?
Calcium-Binding Proteins
1
2015
214
0.110
Why?
Cell Cycle Proteins
1
2018
615
0.110
Why?
Gene Expression Regulation
2
2007
2589
0.100
Why?
Cell Growth Processes
1
2013
53
0.100
Why?
Cellular Senescence
1
2015
190
0.100
Why?
Insulin-Like Growth Factor Binding Protein 2
1
2012
8
0.100
Why?
Tumor Suppressor Proteins
1
2015
323
0.100
Why?
Disease Models, Animal
4
2018
4308
0.100
Why?
DNA-Binding Proteins
3
2016
1476
0.100
Why?
Random Allocation
1
2013
361
0.100
Why?
Enzyme Activation
6
2003
818
0.100
Why?
Aldehyde Dehydrogenase, Mitochondrial
3
2017
23
0.090
Why?
Gene Knockdown Techniques
1
2013
328
0.090
Why?
Molecular Targeted Therapy
1
2015
412
0.090
Why?
Chemokine CXCL12
1
2012
84
0.090
Why?
Receptors, CXCR4
1
2012
88
0.090
Why?
Cyclosporine
1
2013
268
0.090
Why?
Linkage Disequilibrium
2
2012
260
0.090
Why?
Immunoprecipitation
1
2012
152
0.090
Why?
Lung Diseases
3
2004
769
0.090
Why?
Lung
8
2004
4059
0.090
Why?
Hydroxamic Acids
1
2011
91
0.090
Why?
Melanoma
1
2018
765
0.090
Why?
Prognosis
3
2015
4017
0.090
Why?
Peroxidase
2
2002
179
0.090
Why?
Genetic Markers
1
2012
345
0.090
Why?
Drug Design
1
2012
165
0.090
Why?
PTEN Phosphohydrolase
1
2012
163
0.090
Why?
Sirolimus
1
2012
276
0.080
Why?
Antibodies, Monoclonal, Humanized
2
2013
825
0.080
Why?
Genetic Association Studies
1
2012
373
0.080
Why?
Histone Deacetylase Inhibitors
1
2011
207
0.080
Why?
Administration, Oral
1
2012
788
0.080
Why?
Phosphorylation
3
2018
1761
0.080
Why?
Cetuximab
3
2016
98
0.080
Why?
Tumor Necrosis Factor-alpha
4
2004
1245
0.080
Why?
Cell Separation
1
2010
317
0.080
Why?
Membrane Proteins
1
2015
1152
0.070
Why?
Gene Expression Regulation, Neoplastic
4
2016
1388
0.070
Why?
G2 Phase Cell Cycle Checkpoints
2
2018
44
0.070
Why?
Antibodies, Monoclonal
1
2015
1437
0.070
Why?
Models, Statistical
1
2012
667
0.070
Why?
Genetic Variation
2
2012
1002
0.070
Why?
Cells, Cultured
6
2007
4159
0.060
Why?
HT29 Cells
2
2018
41
0.060
Why?
Gene Expression
2
2003
1491
0.060
Why?
Europe
1
2007
406
0.060
Why?
ErbB Receptors
3
2016
611
0.060
Why?
Clinical Trials as Topic
2
2015
1032
0.060
Why?
Flow Cytometry
1
2010
1197
0.060
Why?
Thymine
1
2006
15
0.060
Why?
Genome, Human
1
2008
418
0.060
Why?
Cytosine
1
2006
48
0.060
Why?
Interleukin-1 Receptor-Associated Kinases
1
2006
30
0.060
Why?
Phentolamine
2
2002
18
0.060
Why?
Tumor Burden
2
2018
307
0.060
Why?
Inflammation Mediators
2
2006
511
0.060
Why?
Homozygote
1
2006
203
0.060
Why?
MAP Kinase Kinase 2
2
2002
28
0.060
Why?
MicroRNAs
1
2012
677
0.060
Why?
Translocation, Genetic
1
2006
108
0.060
Why?
Propranolol
2
2002
43
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2007
980
0.060
Why?
Survival Analysis
1
2008
1313
0.060
Why?
MAP Kinase Kinase 1
2
2002
75
0.060
Why?
Adolescent
3
2011
21503
0.060
Why?
Spheroids, Cellular
2
2016
75
0.060
Why?
Cell Nucleus
2
2006
611
0.060
Why?
Models, Biological
2
2018
1785
0.060
Why?
Introns
1
2006
256
0.060
Why?
Mitogen-Activated Protein Kinase 3
2
2002
149
0.060
Why?
Exons
1
2006
355
0.060
Why?
Heat-Shock Proteins
1
2005
143
0.060
Why?
Neoplasm Invasiveness
2
2016
501
0.050
Why?
Bone Marrow Cells
2
2003
322
0.050
Why?
Positron-Emission Tomography
2
2018
302
0.050
Why?
Cause of Death
1
2006
425
0.050
Why?
Shock, Septic
1
2006
206
0.050
Why?
Oxidants
1
2003
112
0.050
Why?
Paclitaxel
1
2024
237
0.050
Why?
Ribosomal Protein S6 Kinases
1
2002
25
0.050
Why?
Deoxycytidine
1
2024
193
0.050
Why?
Organoids
1
2024
120
0.050
Why?
Brimonidine Tartrate
1
2002
10
0.050
Why?
Models, Genetic
1
2005
590
0.050
Why?
Phenylephrine
1
2002
75
0.050
Why?
RNA Interference
2
2016
469
0.050
Why?
Quinoxalines
1
2002
65
0.050
Why?
Isoenzymes
1
2003
304
0.050
Why?
Hydrogen Peroxide
1
2003
332
0.050
Why?
Protein-Tyrosine Kinases
2
2002
431
0.050
Why?
Transcription, Genetic
2
2006
1458
0.050
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
129
0.050
Why?
Lung Neoplasms
1
2015
2530
0.040
Why?
Membrane Glycoproteins
1
2004
500
0.040
Why?
Free Radical Scavengers
1
2001
87
0.040
Why?
Neoplasm Proteins
3
2016
433
0.040
Why?
High Mobility Group Proteins
1
2000
44
0.040
Why?
Imidazoles
1
2001
238
0.040
Why?
MAP Kinase Signaling System
1
2002
322
0.040
Why?
Neutropenia
1
2000
158
0.040
Why?
Interleukin-1
2
2000
964
0.040
Why?
Transcriptome
2
2016
969
0.040
Why?
Protein Processing, Post-Translational
1
2002
463
0.040
Why?
Nuclear Proteins
2
2001
708
0.040
Why?
Adjuvants, Immunologic
1
2000
238
0.040
Why?
Trans-Activators
1
2001
395
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
24
0.040
Why?
Colorado
1
2008
4526
0.040
Why?
4-Aminobenzoic Acid
1
2018
8
0.040
Why?
Up-Regulation
2
2016
846
0.030
Why?
Biomarkers
1
2008
4101
0.030
Why?
Protein Transport
1
2018
440
0.030
Why?
Pneumonia
1
2003
640
0.030
Why?
Retinal Dehydrogenase
1
2016
29
0.030
Why?
Inhibitory Concentration 50
1
2016
88
0.030
Why?
Hyaluronan Receptors
1
2016
102
0.030
Why?
Blotting, Western
2
2013
1224
0.030
Why?
Tissue Array Analysis
1
2016
51
0.030
Why?
Protein Interaction Maps
1
2016
50
0.030
Why?
Mice, Inbred C57BL
4
2015
5770
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
121
0.030
Why?
Drug Screening Assays, Antitumor
1
2016
193
0.030
Why?
Chromatin Immunoprecipitation
1
2016
135
0.030
Why?
Papillomaviridae
1
2016
133
0.030
Why?
Prospective Studies
1
2007
7611
0.030
Why?
S-Phase Kinase-Associated Proteins
1
2015
20
0.030
Why?
Diphenylamine
1
2014
9
0.030
Why?
Iloprost
1
2015
45
0.030
Why?
Cadherins
1
2016
202
0.030
Why?
Acid Phosphatase
1
2014
20
0.030
Why?
Rhodamines
1
2014
20
0.030
Why?
Cell Division
1
2016
790
0.030
Why?
G2 Phase
1
2014
39
0.030
Why?
Gene Expression Regulation, Enzymologic
1
2016
276
0.030
Why?
Tumor Cells, Cultured
1
2016
947
0.030
Why?
Young Adult
1
2011
13298
0.030
Why?
Inflammation
1
2005
2843
0.030
Why?
Epithelial-Mesenchymal Transition
1
2016
211
0.030
Why?
Tretinoin
1
2015
122
0.030
Why?
Sequence Analysis, RNA
1
2016
451
0.030
Why?
Benzamides
1
2014
212
0.030
Why?
Antigens, CD
1
2016
530
0.030
Why?
Transfection
1
2016
941
0.030
Why?
Receptor, Notch2
1
2013
15
0.030
Why?
Gonanes
1
2013
27
0.030
Why?
Retrospective Studies
1
2011
15842
0.030
Why?
Alphapapillomavirus
1
2013
39
0.020
Why?
Receptors, CXCR
1
2012
3
0.020
Why?
Erlotinib Hydrochloride
1
2012
69
0.020
Why?
Cyclin D1
1
2012
68
0.020
Why?
Myeloid Cell Leukemia Sequence 1 Protein
2
2003
41
0.020
Why?
Disease-Free Survival
1
2014
704
0.020
Why?
Protein Binding
1
2018
2232
0.020
Why?
Active Transport, Cell Nucleus
2
2003
122
0.020
Why?
Tumor Suppressor Protein p53
1
2016
525
0.020
Why?
Computers
1
2012
69
0.020
Why?
Mice, Inbred C3H
2
2004
269
0.020
Why?
Maximum Tolerated Dose
1
2012
204
0.020
Why?
Niacinamide
1
2012
82
0.020
Why?
Tissue Distribution
1
2012
322
0.020
Why?
Phenylurea Compounds
1
2012
97
0.020
Why?
Injections, Intraperitoneal
2
2001
114
0.020
Why?
Mice, Knockout
3
2003
3010
0.020
Why?
Proto-Oncogene Proteins c-myc
1
2012
140
0.020
Why?
Calcium Signaling
1
2013
249
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
2
2003
237
0.020
Why?
Xanthine Oxidase
2
2001
81
0.020
Why?
Acute Disease
2
2004
1006
0.020
Why?
Cluster Analysis
1
2011
515
0.020
Why?
United States
1
2007
14983
0.020
Why?
Ligands
1
2011
665
0.020
Why?
Vascular Endothelial Growth Factor A
1
2012
551
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
342
0.020
Why?
Survival Rate
1
2014
1934
0.020
Why?
Models, Molecular
1
2014
1598
0.020
Why?
Computational Biology
1
2013
650
0.020
Why?
Tumor Microenvironment
1
2012
668
0.020
Why?
Dose-Response Relationship, Drug
1
2012
2027
0.020
Why?
Adiposity
1
2012
522
0.020
Why?
Cell Movement
1
2011
971
0.020
Why?
Mice, Transgenic
2
2003
2166
0.020
Why?
Calcium
1
2013
1183
0.020
Why?
Oxidative Stress
2
2003
1319
0.020
Why?
Magnetic Resonance Imaging
1
2018
3636
0.020
Why?
Neutrophil Infiltration
1
2004
107
0.010
Why?
Permeability
1
2004
160
0.010
Why?
Transcription Factor AP-1
1
2003
88
0.010
Why?
Phosphotransferases
1
2003
24
0.010
Why?
Class Ib Phosphatidylinositol 3-Kinase
1
2003
3
0.010
Why?
bcl-Associated Death Protein
1
2003
9
0.010
Why?
Aconitate Hydratase
1
2003
17
0.010
Why?
Toll-Like Receptors
1
2004
188
0.010
Why?
JNK Mitogen-Activated Protein Kinases
1
2003
160
0.010
Why?
Algorithms
1
2010
1709
0.010
Why?
Lipid Peroxidation
1
2003
151
0.010
Why?
Reproducibility of Results
1
2010
3300
0.010
Why?
Mice, Mutant Strains
1
2003
306
0.010
Why?
Extracellular Space
1
2003
120
0.010
Why?
Metalloporphyrins
1
2003
105
0.010
Why?
Replication Protein C
1
2001
4
0.010
Why?
Tumor Necrosis Factor alpha-Induced Protein 3
1
2001
11
0.010
Why?
bcl-X Protein
1
2001
43
0.010
Why?
Toll-Like Receptor 4
1
2004
272
0.010
Why?
Biological Transport
1
2003
401
0.010
Why?
Cysteine Endopeptidases
1
2001
74
0.010
Why?
Protein Kinases
1
2003
308
0.010
Why?
CREB-Binding Protein
1
2001
33
0.010
Why?
Transcription Factor RelA
1
2001
85
0.010
Why?
Tungsten
1
2001
30
0.010
Why?
Animal Feed
1
2001
54
0.010
Why?
Immune Sera
1
2000
84
0.010
Why?
Proto-Oncogene Proteins c-fos
1
2001
188
0.010
Why?
Mitogen-Activated Protein Kinase 1
1
2001
183
0.010
Why?
Organ Specificity
1
2000
308
0.010
Why?
Endotoxins
1
2000
220
0.010
Why?
Protein Biosynthesis
1
2001
434
0.010
Why?
Antioxidants
1
2003
588
0.010
Why?
Carrier Proteins
1
2003
737
0.010
Why?
Intubation, Intratracheal
1
2000
260
0.010
Why?
Peptides
1
2001
982
0.010
Why?
Treatment Outcome
1
2010
10914
0.010
Why?
Proteins
1
2001
1013
0.010
Why?
Arcaroli's Networks
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