Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Arcaroli

Concepts (369)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
19
2018
844
2.360
Why?
Xenograft Model Antitumor Assays
21
2024
928
1.390
Why?
Antineoplastic Agents
17
2018
2192
1.290
Why?
Drug Resistance, Neoplasm
7
2016
881
0.970
Why?
Quinazolines
4
2012
266
0.960
Why?
Benzodioxoles
3
2012
158
0.920
Why?
Camptothecin
4
2016
140
0.850
Why?
Receptor, Notch1
3
2015
64
0.820
Why?
Aldehyde Dehydrogenase
6
2017
99
0.820
Why?
Mice, Nude
16
2024
682
0.770
Why?
Haplotypes
4
2012
490
0.720
Why?
Phosphatidylinositol 3-Kinases
10
2018
379
0.680
Why?
Gene Dosage
3
2015
148
0.610
Why?
Wnt Signaling Pathway
5
2024
210
0.600
Why?
Neutrophils
13
2007
1134
0.580
Why?
src-Family Kinases
3
2017
93
0.570
Why?
Amyloid Precursor Protein Secretases
3
2014
77
0.570
Why?
Endotoxemia
9
2004
87
0.560
Why?
Pancreatic Neoplasms
6
2024
918
0.560
Why?
Anilides
2
2018
84
0.550
Why?
Enzyme Inhibitors
5
2016
824
0.550
Why?
Protein Kinase Inhibitors
9
2018
968
0.530
Why?
Biomarkers, Tumor
9
2018
1313
0.510
Why?
Mice
41
2024
18329
0.500
Why?
Acute Lung Injury
2
2011
302
0.490
Why?
Tankyrases
1
2016
13
0.480
Why?
Receptors, Notch
2
2015
92
0.480
Why?
Cell Line, Tumor
21
2024
3539
0.470
Why?
Pyridines
4
2018
605
0.460
Why?
Drug Discovery
1
2016
154
0.450
Why?
Polymorphism, Genetic
3
2007
612
0.450
Why?
NF-kappa B
13
2007
661
0.440
Why?
3' Untranslated Regions
2
2012
152
0.430
Why?
DNA Copy Number Variations
1
2015
183
0.420
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2014
85
0.420
Why?
Proto-Oncogene Proteins c-met
1
2014
75
0.410
Why?
Tetrahydronaphthalenes
1
2013
31
0.390
Why?
Valine
1
2013
80
0.390
Why?
Animals
44
2024
38030
0.370
Why?
Mitogen-Activated Protein Kinases
7
2014
292
0.370
Why?
Lipopolysaccharides
9
2007
863
0.340
Why?
Sepsis
3
2007
640
0.340
Why?
Signal Transduction
17
2018
5221
0.340
Why?
Superoxide Dismutase
3
2008
301
0.330
Why?
Proto-Oncogene Proteins
8
2018
623
0.320
Why?
Urokinase-Type Plasminogen Activator
2
2007
24
0.320
Why?
Cell Proliferation
13
2024
2494
0.310
Why?
Interleukins
1
2011
248
0.300
Why?
Neoplasm Metastasis
4
2016
688
0.300
Why?
Hemorrhage
6
2004
809
0.280
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
108
0.280
Why?
Heterografts
3
2018
143
0.280
Why?
Apoptosis
11
2018
2430
0.270
Why?
HCT116 Cells
4
2018
78
0.270
Why?
SOXB1 Transcription Factors
2
2018
67
0.250
Why?
Carcinoma, Pancreatic Ductal
2
2024
291
0.250
Why?
Azepines
2
2018
107
0.250
Why?
Promoter Regions, Genetic
1
2011
1255
0.240
Why?
Benzimidazoles
3
2013
190
0.240
Why?
Mutation
3
2012
4085
0.240
Why?
Immunoblotting
5
2015
300
0.240
Why?
Receptors, Interleukin-1
1
2006
213
0.220
Why?
Neutrophil Activation
5
2003
85
0.220
Why?
beta Catenin
3
2016
252
0.220
Why?
Oligonucleotide Array Sequence Analysis
6
2015
758
0.210
Why?
Humans
46
2024
144261
0.210
Why?
TOR Serine-Threonine Kinases
4
2018
449
0.210
Why?
Pyrimidines
2
2018
532
0.200
Why?
Intracellular Signaling Peptides and Proteins
2
2006
459
0.200
Why?
Mice, Inbred BALB C
10
2003
1253
0.200
Why?
Adrenergic alpha-Antagonists
2
2002
34
0.200
Why?
Proto-Oncogene Proteins c-akt
8
2018
436
0.200
Why?
Colonic Neoplasms
2
2016
259
0.190
Why?
Adrenergic alpha-Agonists
1
2002
27
0.190
Why?
Proto-Oncogene Proteins c-raf
1
2002
45
0.190
Why?
Genetic Predisposition to Disease
1
2011
2359
0.180
Why?
Neuroimmunomodulation
1
2002
68
0.180
Why?
ras Proteins
3
2013
150
0.180
Why?
Adrenergic beta-Agonists
1
2002
91
0.180
Why?
Female
24
2018
77976
0.180
Why?
Adrenergic beta-Antagonists
2
2002
250
0.180
Why?
Aged
11
2016
25850
0.170
Why?
Middle Aged
12
2016
35762
0.160
Why?
Hemoptysis
1
2000
36
0.160
Why?
Polymorphism, Single Nucleotide
4
2011
2143
0.160
Why?
In Situ Hybridization, Fluorescence
2
2012
322
0.160
Why?
Cytokines
4
2005
2061
0.150
Why?
Carcinoma, Squamous Cell
2
2016
641
0.150
Why?
Head and Neck Neoplasms
2
2016
556
0.150
Why?
Adult
11
2016
40262
0.150
Why?
Cell Transformation, Neoplastic
2
2018
339
0.150
Why?
DNA Topoisomerases, Type II
2
2016
47
0.140
Why?
Male
24
2016
72035
0.140
Why?
CDC2 Protein Kinase
1
2018
27
0.140
Why?
Transplantation, Heterologous
2
2016
193
0.140
Why?
MAP Kinase Kinase Kinases
2
2015
70
0.140
Why?
Oncogene Proteins v-abl
1
2017
5
0.140
Why?
Cyclic AMP Response Element-Binding Protein
4
2003
145
0.140
Why?
Mitogen-Activated Protein Kinase Kinases
3
2010
128
0.130
Why?
p38 Mitogen-Activated Protein Kinases
6
2007
266
0.130
Why?
Immunohistochemistry
5
2017
1715
0.130
Why?
Proto-Oncogene Proteins p21(ras)
5
2016
253
0.130
Why?
Dasatinib
1
2017
57
0.130
Why?
Gene Expression Profiling
4
2018
1782
0.130
Why?
Case-Control Studies
3
2011
3592
0.130
Why?
Antigens, Neoplasm
2
2016
271
0.130
Why?
Angiogenesis Inhibitors
2
2018
236
0.130
Why?
Intercellular Signaling Peptides and Proteins
2
2015
381
0.130
Why?
Neovascularization, Pathologic
2
2018
286
0.130
Why?
Phosphatidylinositol 3-Kinase
1
2016
25
0.120
Why?
Receptors, Cell Surface
2
2012
377
0.120
Why?
Axin Protein
1
2016
19
0.120
Why?
Corynebacterium
1
2017
49
0.120
Why?
Adenocarcinoma
2
2014
927
0.120
Why?
Aurora Kinase A
1
2016
62
0.120
Why?
Corynebacterium Infections
1
2017
42
0.120
Why?
Neoplasms, Experimental
1
2017
173
0.120
Why?
Transcription Factor 7-Like 2 Protein
1
2016
26
0.120
Why?
Cell Cycle
5
2018
596
0.120
Why?
Neoplastic Stem Cells
2
2018
412
0.120
Why?
Autophagy
1
2018
285
0.120
Why?
Genotype
3
2012
1833
0.120
Why?
Serrate-Jagged Proteins
1
2015
27
0.120
Why?
Jagged-1 Protein
1
2015
22
0.120
Why?
RNA, Small Interfering
2
2015
634
0.110
Why?
Drug Synergism
2
2014
357
0.110
Why?
Gene Duplication
1
2015
67
0.110
Why?
Retinaldehyde
1
2015
4
0.110
Why?
RNA, Messenger
5
2016
2829
0.110
Why?
HMGB1 Protein
2
2007
51
0.110
Why?
Acetaldehyde
1
2015
17
0.110
Why?
Neoplasms
3
2016
2870
0.110
Why?
Chemokines
5
2003
218
0.110
Why?
Aged, 80 and over
5
2014
8243
0.110
Why?
Pyrimidinones
1
2015
126
0.110
Why?
Acridines
1
2014
9
0.110
Why?
Neoplasm Transplantation
4
2016
251
0.110
Why?
Chemokine CXCL2
4
2001
41
0.110
Why?
Topoisomerase II Inhibitors
1
2014
26
0.110
Why?
Pyrazoles
1
2018
509
0.110
Why?
Antineoplastic Combined Chemotherapy Protocols
3
2014
1953
0.100
Why?
Wnt Proteins
1
2015
133
0.100
Why?
Benzazepines
1
2014
35
0.100
Why?
Calcium-Binding Proteins
1
2015
219
0.100
Why?
Pyridones
1
2015
198
0.100
Why?
Gene Expression Regulation
2
2007
2603
0.100
Why?
Cell Cycle Proteins
1
2018
628
0.100
Why?
Respiration, Artificial
2
2011
707
0.100
Why?
Cell Growth Processes
1
2013
50
0.100
Why?
Insulin-Like Growth Factor Binding Protein 2
1
2012
8
0.090
Why?
Tumor Suppressor Proteins
1
2015
321
0.090
Why?
Enzyme Activation
6
2003
765
0.090
Why?
Cellular Senescence
1
2015
226
0.090
Why?
Random Allocation
1
2013
363
0.090
Why?
DNA-Binding Proteins
3
2016
1497
0.090
Why?
Gene Knockdown Techniques
1
2013
336
0.090
Why?
Molecular Targeted Therapy
1
2015
431
0.090
Why?
Aldehyde Dehydrogenase, Mitochondrial
3
2017
23
0.090
Why?
Disease Models, Animal
4
2018
4556
0.090
Why?
Chemokine CXCL12
1
2012
89
0.090
Why?
Cyclosporine
1
2013
265
0.090
Why?
Receptors, CXCR4
1
2012
91
0.090
Why?
Linkage Disequilibrium
2
2012
246
0.090
Why?
Immunoprecipitation
1
2012
151
0.090
Why?
Melanoma
1
2018
760
0.090
Why?
Hydroxamic Acids
1
2011
94
0.090
Why?
Lung Diseases
3
2004
787
0.090
Why?
Lung
8
2004
4108
0.090
Why?
Genetic Markers
1
2012
331
0.080
Why?
Peroxidase
2
2002
168
0.080
Why?
Prognosis
3
2015
4278
0.080
Why?
Drug Design
1
2012
173
0.080
Why?
PTEN Phosphohydrolase
1
2012
164
0.080
Why?
Sirolimus
1
2012
281
0.080
Why?
Genetic Association Studies
1
2012
372
0.080
Why?
Histone Deacetylase Inhibitors
1
2011
220
0.080
Why?
Antibodies, Monoclonal, Humanized
2
2013
985
0.080
Why?
Administration, Oral
1
2012
847
0.080
Why?
Phosphorylation
3
2018
1732
0.080
Why?
Tumor Necrosis Factor-alpha
4
2004
1217
0.080
Why?
Cetuximab
3
2016
111
0.080
Why?
Cell Separation
1
2010
307
0.070
Why?
Membrane Proteins
1
2015
1165
0.070
Why?
G2 Phase Cell Cycle Checkpoints
2
2018
44
0.070
Why?
Gene Expression Regulation, Neoplastic
4
2016
1455
0.070
Why?
Antibodies, Monoclonal
1
2015
1519
0.070
Why?
Models, Statistical
1
2012
677
0.070
Why?
Genetic Variation
2
2012
982
0.070
Why?
Cells, Cultured
6
2007
4146
0.060
Why?
HT29 Cells
2
2018
37
0.060
Why?
Gene Expression
2
2003
1487
0.060
Why?
Europe
1
2007
412
0.060
Why?
ErbB Receptors
3
2016
627
0.060
Why?
Flow Cytometry
1
2010
1172
0.060
Why?
Thymine
1
2006
17
0.060
Why?
Clinical Trials as Topic
2
2015
1050
0.060
Why?
Genome, Human
1
2008
422
0.060
Why?
Cytosine
1
2006
51
0.060
Why?
Interleukin-1 Receptor-Associated Kinases
1
2006
40
0.060
Why?
Phentolamine
2
2002
20
0.060
Why?
Inflammation Mediators
2
2006
508
0.060
Why?
Tumor Burden
2
2018
319
0.060
Why?
MicroRNAs
1
2012
700
0.060
Why?
Homozygote
1
2006
199
0.060
Why?
MAP Kinase Kinase 2
2
2002
29
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2007
981
0.060
Why?
Translocation, Genetic
1
2006
115
0.060
Why?
Propranolol
2
2002
44
0.060
Why?
MAP Kinase Kinase 1
2
2002
71
0.060
Why?
Survival Analysis
1
2008
1382
0.060
Why?
Spheroids, Cellular
2
2016
73
0.060
Why?
Cell Nucleus
2
2006
618
0.060
Why?
Mitogen-Activated Protein Kinase 3
2
2002
138
0.060
Why?
Adolescent
3
2011
22281
0.050
Why?
Introns
1
2006
254
0.050
Why?
Heat-Shock Proteins
1
2005
138
0.050
Why?
Exons
1
2006
358
0.050
Why?
Models, Biological
2
2018
1820
0.050
Why?
Bone Marrow Cells
2
2003
320
0.050
Why?
Neoplasm Invasiveness
2
2016
508
0.050
Why?
Shock, Septic
1
2006
215
0.050
Why?
Positron-Emission Tomography
2
2018
323
0.050
Why?
Cause of Death
1
2006
464
0.050
Why?
Oxidants
1
2003
103
0.050
Why?
Models, Genetic
1
2005
535
0.050
Why?
Paclitaxel
1
2024
255
0.050
Why?
Ribosomal Protein S6 Kinases
1
2002
24
0.050
Why?
Brimonidine Tartrate
1
2002
10
0.050
Why?
Deoxycytidine
1
2024
221
0.050
Why?
Phenylephrine
1
2002
75
0.050
Why?
RNA Interference
2
2016
476
0.050
Why?
Organoids
1
2024
141
0.050
Why?
Protein-Tyrosine Kinases
2
2002
433
0.050
Why?
Isoenzymes
1
2003
299
0.050
Why?
Quinoxalines
1
2002
65
0.050
Why?
Hydrogen Peroxide
1
2003
336
0.040
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
125
0.040
Why?
Transcription, Genetic
2
2006
1495
0.040
Why?
Lung Neoplasms
1
2015
2637
0.040
Why?
Membrane Glycoproteins
1
2004
496
0.040
Why?
Free Radical Scavengers
1
2001
81
0.040
Why?
Neoplasm Proteins
3
2016
442
0.040
Why?
High Mobility Group Proteins
1
2000
45
0.040
Why?
MAP Kinase Signaling System
1
2002
309
0.040
Why?
Imidazoles
1
2001
254
0.040
Why?
Interleukin-1
2
2000
961
0.040
Why?
Neutropenia
1
2000
155
0.040
Why?
Protein Processing, Post-Translational
1
2002
477
0.040
Why?
Nuclear Proteins
2
2001
748
0.040
Why?
Transcriptome
2
2016
1044
0.040
Why?
Adjuvants, Immunologic
1
2000
245
0.040
Why?
Trans-Activators
1
2001
405
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
24
0.040
Why?
Colorado
1
2008
4562
0.030
Why?
4-Aminobenzoic Acid
1
2018
8
0.030
Why?
Up-Regulation
2
2016
851
0.030
Why?
Biomarkers
1
2008
4254
0.030
Why?
Protein Transport
1
2018
441
0.030
Why?
Pneumonia
1
2003
630
0.030
Why?
Retinal Dehydrogenase
1
2016
29
0.030
Why?
Inhibitory Concentration 50
1
2016
91
0.030
Why?
Blotting, Western
2
2013
1187
0.030
Why?
Hyaluronan Receptors
1
2016
102
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
112
0.030
Why?
Tissue Array Analysis
1
2016
50
0.030
Why?
Protein Interaction Maps
1
2016
51
0.030
Why?
Papillomaviridae
1
2016
115
0.030
Why?
Drug Screening Assays, Antitumor
1
2016
191
0.030
Why?
Chromatin Immunoprecipitation
1
2016
139
0.030
Why?
Mice, Inbred C57BL
4
2015
5988
0.030
Why?
S-Phase Kinase-Associated Proteins
1
2015
20
0.030
Why?
Prospective Studies
1
2007
7970
0.030
Why?
Diphenylamine
1
2014
8
0.030
Why?
Cadherins
1
2016
200
0.030
Why?
Iloprost
1
2015
44
0.030
Why?
Acid Phosphatase
1
2014
14
0.030
Why?
Cell Division
1
2016
766
0.030
Why?
Tumor Cells, Cultured
1
2016
919
0.030
Why?
Rhodamines
1
2014
21
0.030
Why?
Gene Expression Regulation, Enzymologic
1
2016
269
0.030
Why?
G2 Phase
1
2014
39
0.030
Why?
Young Adult
1
2011
13990
0.030
Why?
Epithelial-Mesenchymal Transition
1
2016
219
0.030
Why?
Inflammation
1
2005
2877
0.030
Why?
Sequence Analysis, RNA
1
2016
442
0.030
Why?
Tretinoin
1
2015
124
0.030
Why?
Benzamides
1
2014
224
0.030
Why?
Transfection
1
2016
938
0.020
Why?
Receptor, Notch2
1
2013
15
0.020
Why?
Antigens, CD
1
2016
555
0.020
Why?
Gonanes
1
2013
28
0.020
Why?
Alphapapillomavirus
1
2013
35
0.020
Why?
Retrospective Studies
1
2011
17009
0.020
Why?
Receptors, CXCR
1
2012
5
0.020
Why?
Myeloid Cell Leukemia Sequence 1 Protein
2
2003
39
0.020
Why?
Erlotinib Hydrochloride
1
2012
72
0.020
Why?
Cyclin D1
1
2012
61
0.020
Why?
Tumor Suppressor Protein p53
1
2016
529
0.020
Why?
Active Transport, Cell Nucleus
2
2003
121
0.020
Why?
Protein Binding
1
2018
2270
0.020
Why?
Mice, Inbred C3H
2
2004
251
0.020
Why?
Computers
1
2012
67
0.020
Why?
Disease-Free Survival
1
2014
768
0.020
Why?
Fluorocarbons
1
2014
143
0.020
Why?
Maximum Tolerated Dose
1
2012
212
0.020
Why?
Niacinamide
1
2012
86
0.020
Why?
Tissue Distribution
1
2012
327
0.020
Why?
Phenylurea Compounds
1
2012
112
0.020
Why?
Injections, Intraperitoneal
2
2001
116
0.020
Why?
Calcium Signaling
1
2013
251
0.020
Why?
Mice, Knockout
3
2003
3119
0.020
Why?
Xanthine Oxidase
2
2001
79
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
2
2003
240
0.020
Why?
Proto-Oncogene Proteins c-myc
1
2012
167
0.020
Why?
Acute Disease
2
2004
1028
0.020
Why?
Cluster Analysis
1
2011
519
0.020
Why?
United States
1
2007
15876
0.020
Why?
Ligands
1
2011
673
0.020
Why?
Vascular Endothelial Growth Factor A
1
2012
557
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
346
0.020
Why?
Models, Molecular
1
2014
1618
0.020
Why?
Survival Rate
1
2014
2088
0.020
Why?
Computational Biology
1
2013
680
0.020
Why?
Tumor Microenvironment
1
2012
732
0.020
Why?
Dose-Response Relationship, Drug
1
2012
2026
0.020
Why?
Adiposity
1
2012
541
0.020
Why?
Calcium
1
2013
1182
0.020
Why?
Mice, Transgenic
2
2003
2182
0.020
Why?
Cell Movement
1
2011
965
0.020
Why?
Oxidative Stress
2
2003
1339
0.020
Why?
Magnetic Resonance Imaging
1
2018
3857
0.010
Why?
Neutrophil Infiltration
1
2004
104
0.010
Why?
Permeability
1
2004
168
0.010
Why?
Transcription Factor AP-1
1
2003
79
0.010
Why?
Phosphotransferases
1
2003
27
0.010
Why?
bcl-Associated Death Protein
1
2003
8
0.010
Why?
Class Ib Phosphatidylinositol 3-Kinase
1
2003
5
0.010
Why?
Aconitate Hydratase
1
2003
14
0.010
Why?
JNK Mitogen-Activated Protein Kinases
1
2003
153
0.010
Why?
Toll-Like Receptors
1
2004
194
0.010
Why?
Metalloporphyrins
1
2003
66
0.010
Why?
Algorithms
1
2010
1834
0.010
Why?
Mice, Mutant Strains
1
2003
299
0.010
Why?
Lipid Peroxidation
1
2003
160
0.010
Why?
Extracellular Space
1
2003
120
0.010
Why?
Reproducibility of Results
1
2010
3403
0.010
Why?
Replication Protein C
1
2001
4
0.010
Why?
Tumor Necrosis Factor alpha-Induced Protein 3
1
2001
12
0.010
Why?
bcl-X Protein
1
2001
45
0.010
Why?
Toll-Like Receptor 4
1
2004
276
0.010
Why?
Biological Transport
1
2003
412
0.010
Why?
Cysteine Endopeptidases
1
2001
73
0.010
Why?
Protein Kinases
1
2003
315
0.010
Why?
CREB-Binding Protein
1
2001
34
0.010
Why?
Transcription Factor RelA
1
2001
85
0.010
Why?
Tungsten
1
2001
30
0.010
Why?
Animal Feed
1
2001
53
0.010
Why?
Immune Sera
1
2000
77
0.010
Why?
Proto-Oncogene Proteins c-fos
1
2001
196
0.010
Why?
Mitogen-Activated Protein Kinase 1
1
2001
175
0.010
Why?
Organ Specificity
1
2000
312
0.010
Why?
Endotoxins
1
2000
220
0.010
Why?
Antioxidants
1
2003
549
0.010
Why?
Carrier Proteins
1
2003
736
0.010
Why?
Protein Biosynthesis
1
2001
458
0.010
Why?
Intubation, Intratracheal
1
2000
320
0.010
Why?
Peptides
1
2001
995
0.010
Why?
Proteins
1
2001
1021
0.010
Why?
Treatment Outcome
1
2010
11643
0.010
Why?
Arcaroli's Networks
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