Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Arcaroli

Concepts (369)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
19
2018
809
2.430
Why?
Xenograft Model Antitumor Assays
21
2024
917
1.420
Why?
Antineoplastic Agents
17
2018
2163
1.320
Why?
Drug Resistance, Neoplasm
7
2016
841
1.000
Why?
Quinazolines
4
2012
259
0.980
Why?
Benzodioxoles
3
2012
138
0.960
Why?
Camptothecin
4
2016
123
0.870
Why?
Receptor, Notch1
3
2015
65
0.840
Why?
Aldehyde Dehydrogenase
6
2017
100
0.840
Why?
Mice, Nude
16
2024
700
0.780
Why?
Haplotypes
4
2012
499
0.730
Why?
Phosphatidylinositol 3-Kinases
10
2018
369
0.700
Why?
Gene Dosage
3
2015
142
0.620
Why?
Wnt Signaling Pathway
5
2024
203
0.620
Why?
Neutrophils
13
2007
1283
0.590
Why?
src-Family Kinases
3
2017
94
0.580
Why?
Amyloid Precursor Protein Secretases
3
2014
79
0.580
Why?
Pancreatic Neoplasms
6
2024
889
0.570
Why?
Endotoxemia
9
2004
87
0.570
Why?
Anilides
2
2018
81
0.560
Why?
Enzyme Inhibitors
5
2016
843
0.560
Why?
Protein Kinase Inhibitors
9
2018
918
0.550
Why?
Biomarkers, Tumor
9
2018
1248
0.530
Why?
Mice
41
2024
18092
0.510
Why?
Acute Lung Injury
2
2011
304
0.500
Why?
Receptors, Notch
2
2015
87
0.490
Why?
Tankyrases
1
2016
13
0.490
Why?
Pyridines
4
2018
558
0.480
Why?
Cell Line, Tumor
21
2024
3504
0.480
Why?
Drug Discovery
1
2016
146
0.460
Why?
Polymorphism, Genetic
3
2007
625
0.460
Why?
NF-kappa B
13
2007
690
0.450
Why?
3' Untranslated Regions
2
2012
149
0.440
Why?
DNA Copy Number Variations
1
2015
178
0.430
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2014
85
0.430
Why?
Proto-Oncogene Proteins c-met
1
2014
72
0.420
Why?
Tetrahydronaphthalenes
1
2013
30
0.400
Why?
Valine
1
2013
79
0.390
Why?
Animals
44
2024
37642
0.380
Why?
Mitogen-Activated Protein Kinases
7
2014
315
0.370
Why?
Lipopolysaccharides
9
2007
888
0.350
Why?
Sepsis
3
2007
628
0.350
Why?
Signal Transduction
17
2018
5153
0.340
Why?
Proto-Oncogene Proteins
8
2018
626
0.330
Why?
Superoxide Dismutase
3
2008
350
0.330
Why?
Urokinase-Type Plasminogen Activator
2
2007
30
0.320
Why?
Cell Proliferation
13
2024
2504
0.310
Why?
Interleukins
1
2011
250
0.310
Why?
Neoplasm Metastasis
4
2016
676
0.300
Why?
Hemorrhage
6
2004
782
0.290
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
100
0.290
Why?
Heterografts
3
2018
135
0.280
Why?
HCT116 Cells
4
2018
80
0.270
Why?
Apoptosis
11
2018
2575
0.270
Why?
SOXB1 Transcription Factors
2
2018
66
0.260
Why?
Carcinoma, Pancreatic Ductal
2
2024
285
0.250
Why?
Azepines
2
2018
98
0.250
Why?
Promoter Regions, Genetic
1
2011
1244
0.250
Why?
Benzimidazoles
3
2013
191
0.250
Why?
Mutation
3
2012
4009
0.250
Why?
Immunoblotting
5
2015
311
0.240
Why?
Receptors, Interleukin-1
1
2006
215
0.230
Why?
Neutrophil Activation
5
2003
87
0.230
Why?
beta Catenin
3
2016
258
0.220
Why?
Humans
46
2024
141267
0.220
Why?
Oligonucleotide Array Sequence Analysis
6
2015
758
0.220
Why?
TOR Serine-Threonine Kinases
4
2018
428
0.220
Why?
Pyrimidines
2
2018
511
0.210
Why?
Intracellular Signaling Peptides and Proteins
2
2006
467
0.200
Why?
Adrenergic alpha-Antagonists
2
2002
34
0.200
Why?
Mice, Inbred BALB C
10
2003
1271
0.200
Why?
Proto-Oncogene Proteins c-akt
8
2018
442
0.200
Why?
Colonic Neoplasms
2
2016
244
0.200
Why?
Proto-Oncogene Proteins c-raf
1
2002
44
0.190
Why?
Adrenergic alpha-Agonists
1
2002
28
0.190
Why?
Genetic Predisposition to Disease
1
2011
2373
0.190
Why?
Neuroimmunomodulation
1
2002
65
0.190
Why?
Female
24
2018
75729
0.190
Why?
ras Proteins
3
2013
145
0.190
Why?
Adrenergic beta-Agonists
1
2002
98
0.180
Why?
Aged
11
2016
24798
0.180
Why?
Adrenergic beta-Antagonists
2
2002
230
0.180
Why?
Middle Aged
12
2016
34597
0.170
Why?
Hemoptysis
1
2000
37
0.170
Why?
Polymorphism, Single Nucleotide
4
2011
2132
0.160
Why?
In Situ Hybridization, Fluorescence
2
2012
310
0.160
Why?
Head and Neck Neoplasms
2
2016
555
0.160
Why?
Carcinoma, Squamous Cell
2
2016
641
0.160
Why?
Cytokines
4
2005
2093
0.150
Why?
Adult
11
2016
39203
0.150
Why?
Cell Transformation, Neoplastic
2
2018
334
0.150
Why?
DNA Topoisomerases, Type II
2
2016
45
0.150
Why?
Male
24
2016
70063
0.150
Why?
CDC2 Protein Kinase
1
2018
31
0.140
Why?
Transplantation, Heterologous
2
2016
194
0.140
Why?
MAP Kinase Kinase Kinases
2
2015
71
0.140
Why?
Oncogene Proteins v-abl
1
2017
5
0.140
Why?
Cyclic AMP Response Element-Binding Protein
4
2003
143
0.140
Why?
Mitogen-Activated Protein Kinase Kinases
3
2010
132
0.140
Why?
p38 Mitogen-Activated Protein Kinases
6
2007
281
0.130
Why?
Proto-Oncogene Proteins p21(ras)
5
2016
249
0.130
Why?
Immunohistochemistry
5
2017
1726
0.130
Why?
Dasatinib
1
2017
57
0.130
Why?
Case-Control Studies
3
2011
3580
0.130
Why?
Gene Expression Profiling
4
2018
1769
0.130
Why?
Angiogenesis Inhibitors
2
2018
229
0.130
Why?
Neovascularization, Pathologic
2
2018
295
0.130
Why?
Intercellular Signaling Peptides and Proteins
2
2015
389
0.130
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.130
Why?
Adenocarcinoma
2
2014
896
0.130
Why?
Receptors, Cell Surface
2
2012
398
0.130
Why?
Aurora Kinase A
1
2016
56
0.120
Why?
Axin Protein
1
2016
19
0.120
Why?
Corynebacterium
1
2017
49
0.120
Why?
Corynebacterium Infections
1
2017
42
0.120
Why?
Antigens, Neoplasm
2
2016
324
0.120
Why?
Neoplasms, Experimental
1
2017
175
0.120
Why?
Transcription Factor 7-Like 2 Protein
1
2016
26
0.120
Why?
Cell Cycle
5
2018
601
0.120
Why?
Neoplastic Stem Cells
2
2018
411
0.120
Why?
Autophagy
1
2018
284
0.120
Why?
Serrate-Jagged Proteins
1
2015
27
0.120
Why?
Jagged-1 Protein
1
2015
23
0.120
Why?
Genotype
3
2012
1865
0.120
Why?
RNA, Small Interfering
2
2015
628
0.120
Why?
RNA, Messenger
5
2016
2826
0.120
Why?
Drug Synergism
2
2014
370
0.110
Why?
Gene Duplication
1
2015
65
0.110
Why?
Neoplasms
3
2016
2731
0.110
Why?
Retinaldehyde
1
2015
4
0.110
Why?
Aged, 80 and over
5
2014
7947
0.110
Why?
HMGB1 Protein
2
2007
51
0.110
Why?
Acetaldehyde
1
2015
17
0.110
Why?
Chemokines
5
2003
228
0.110
Why?
Pyrimidinones
1
2015
122
0.110
Why?
Acridines
1
2014
9
0.110
Why?
Neoplasm Transplantation
4
2016
251
0.110
Why?
Pyrazoles
1
2018
482
0.110
Why?
Chemokine CXCL2
4
2001
42
0.110
Why?
Topoisomerase II Inhibitors
1
2014
26
0.110
Why?
Antineoplastic Combined Chemotherapy Protocols
3
2014
1794
0.110
Why?
Benzazepines
1
2014
35
0.110
Why?
Wnt Proteins
1
2015
136
0.110
Why?
Calcium-Binding Proteins
1
2015
217
0.110
Why?
Respiration, Artificial
2
2011
686
0.100
Why?
Pyridones
1
2015
189
0.100
Why?
Gene Expression Regulation
2
2007
2608
0.100
Why?
Cell Cycle Proteins
1
2018
634
0.100
Why?
Cell Growth Processes
1
2013
52
0.100
Why?
Insulin-Like Growth Factor Binding Protein 2
1
2012
8
0.100
Why?
Cellular Senescence
1
2015
206
0.100
Why?
Tumor Suppressor Proteins
1
2015
325
0.100
Why?
DNA-Binding Proteins
3
2016
1483
0.090
Why?
Enzyme Activation
6
2003
801
0.090
Why?
Random Allocation
1
2013
366
0.090
Why?
Disease Models, Animal
4
2018
4413
0.090
Why?
Aldehyde Dehydrogenase, Mitochondrial
3
2017
23
0.090
Why?
Gene Knockdown Techniques
1
2013
332
0.090
Why?
Molecular Targeted Therapy
1
2015
420
0.090
Why?
Chemokine CXCL12
1
2012
84
0.090
Why?
Receptors, CXCR4
1
2012
89
0.090
Why?
Cyclosporine
1
2013
265
0.090
Why?
Linkage Disequilibrium
2
2012
254
0.090
Why?
Immunoprecipitation
1
2012
153
0.090
Why?
Hydroxamic Acids
1
2011
94
0.090
Why?
Lung Diseases
3
2004
793
0.090
Why?
Lung
8
2004
4129
0.090
Why?
Melanoma
1
2018
795
0.090
Why?
Prognosis
3
2015
4077
0.090
Why?
Peroxidase
2
2002
182
0.090
Why?
Genetic Markers
1
2012
343
0.090
Why?
Drug Design
1
2012
169
0.090
Why?
PTEN Phosphohydrolase
1
2012
162
0.080
Why?
Sirolimus
1
2012
276
0.080
Why?
Genetic Association Studies
1
2012
375
0.080
Why?
Histone Deacetylase Inhibitors
1
2011
211
0.080
Why?
Antibodies, Monoclonal, Humanized
2
2013
911
0.080
Why?
Administration, Oral
1
2012
824
0.080
Why?
Phosphorylation
3
2018
1760
0.080
Why?
Tumor Necrosis Factor-alpha
4
2004
1241
0.080
Why?
Cetuximab
3
2016
106
0.080
Why?
Cell Separation
1
2010
317
0.080
Why?
Membrane Proteins
1
2015
1157
0.070
Why?
G2 Phase Cell Cycle Checkpoints
2
2018
45
0.070
Why?
Gene Expression Regulation, Neoplastic
4
2016
1440
0.070
Why?
Antibodies, Monoclonal
1
2015
1472
0.070
Why?
Models, Statistical
1
2012
670
0.070
Why?
Genetic Variation
2
2012
995
0.070
Why?
Cells, Cultured
6
2007
4205
0.060
Why?
HT29 Cells
2
2018
41
0.060
Why?
Gene Expression
2
2003
1492
0.060
Why?
Europe
1
2007
407
0.060
Why?
ErbB Receptors
3
2016
612
0.060
Why?
Clinical Trials as Topic
2
2015
1036
0.060
Why?
Flow Cytometry
1
2010
1196
0.060
Why?
Thymine
1
2006
16
0.060
Why?
Genome, Human
1
2008
423
0.060
Why?
Cytosine
1
2006
48
0.060
Why?
Interleukin-1 Receptor-Associated Kinases
1
2006
37
0.060
Why?
Phentolamine
2
2002
20
0.060
Why?
Tumor Burden
2
2018
313
0.060
Why?
Homozygote
1
2006
201
0.060
Why?
Inflammation Mediators
2
2006
517
0.060
Why?
MAP Kinase Kinase 2
2
2002
28
0.060
Why?
MicroRNAs
1
2012
694
0.060
Why?
Translocation, Genetic
1
2006
110
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2007
985
0.060
Why?
Propranolol
2
2002
45
0.060
Why?
Survival Analysis
1
2008
1323
0.060
Why?
MAP Kinase Kinase 1
2
2002
75
0.060
Why?
Cell Nucleus
2
2006
610
0.060
Why?
Spheroids, Cellular
2
2016
78
0.060
Why?
Adolescent
3
2011
22064
0.060
Why?
Introns
1
2006
253
0.060
Why?
Mitogen-Activated Protein Kinase 3
2
2002
150
0.060
Why?
Heat-Shock Proteins
1
2005
141
0.060
Why?
Models, Biological
2
2018
1826
0.060
Why?
Exons
1
2006
352
0.060
Why?
Neoplasm Invasiveness
2
2016
509
0.050
Why?
Bone Marrow Cells
2
2003
327
0.050
Why?
Positron-Emission Tomography
2
2018
310
0.050
Why?
Cause of Death
1
2006
446
0.050
Why?
Shock, Septic
1
2006
213
0.050
Why?
Oxidants
1
2003
111
0.050
Why?
Paclitaxel
1
2024
235
0.050
Why?
Ribosomal Protein S6 Kinases
1
2002
25
0.050
Why?
Brimonidine Tartrate
1
2002
10
0.050
Why?
Models, Genetic
1
2005
588
0.050
Why?
Deoxycytidine
1
2024
202
0.050
Why?
Phenylephrine
1
2002
75
0.050
Why?
Organoids
1
2024
130
0.050
Why?
RNA Interference
2
2016
468
0.050
Why?
Isoenzymes
1
2003
301
0.050
Why?
Quinoxalines
1
2002
67
0.050
Why?
Protein-Tyrosine Kinases
2
2002
430
0.050
Why?
Hydrogen Peroxide
1
2003
339
0.050
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
129
0.040
Why?
Transcription, Genetic
2
2006
1493
0.040
Why?
Lung Neoplasms
1
2015
2555
0.040
Why?
Membrane Glycoproteins
1
2004
501
0.040
Why?
Free Radical Scavengers
1
2001
87
0.040
Why?
Neoplasm Proteins
3
2016
435
0.040
Why?
High Mobility Group Proteins
1
2000
44
0.040
Why?
MAP Kinase Signaling System
1
2002
324
0.040
Why?
Imidazoles
1
2001
255
0.040
Why?
Neutropenia
1
2000
155
0.040
Why?
Interleukin-1
2
2000
973
0.040
Why?
Protein Processing, Post-Translational
1
2002
463
0.040
Why?
Nuclear Proteins
2
2001
718
0.040
Why?
Transcriptome
2
2016
1010
0.040
Why?
Adjuvants, Immunologic
1
2000
238
0.040
Why?
Trans-Activators
1
2001
394
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
24
0.040
Why?
4-Aminobenzoic Acid
1
2018
8
0.040
Why?
Colorado
1
2008
4599
0.040
Why?
Up-Regulation
2
2016
856
0.030
Why?
Biomarkers
1
2008
4179
0.030
Why?
Protein Transport
1
2018
448
0.030
Why?
Retinal Dehydrogenase
1
2016
29
0.030
Why?
Pneumonia
1
2003
656
0.030
Why?
Inhibitory Concentration 50
1
2016
91
0.030
Why?
Blotting, Western
2
2013
1232
0.030
Why?
Hyaluronan Receptors
1
2016
104
0.030
Why?
Tissue Array Analysis
1
2016
51
0.030
Why?
Protein Interaction Maps
1
2016
49
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
123
0.030
Why?
Drug Screening Assays, Antitumor
1
2016
195
0.030
Why?
Papillomaviridae
1
2016
121
0.030
Why?
Mice, Inbred C57BL
4
2015
5901
0.030
Why?
Chromatin Immunoprecipitation
1
2016
136
0.030
Why?
S-Phase Kinase-Associated Proteins
1
2015
20
0.030
Why?
Prospective Studies
1
2007
7787
0.030
Why?
Diphenylamine
1
2014
9
0.030
Why?
Iloprost
1
2015
44
0.030
Why?
Cadherins
1
2016
201
0.030
Why?
Acid Phosphatase
1
2014
20
0.030
Why?
Rhodamines
1
2014
20
0.030
Why?
Gene Expression Regulation, Enzymologic
1
2016
270
0.030
Why?
Cell Division
1
2016
793
0.030
Why?
G2 Phase
1
2014
39
0.030
Why?
Tumor Cells, Cultured
1
2016
960
0.030
Why?
Young Adult
1
2011
13667
0.030
Why?
Inflammation
1
2005
2895
0.030
Why?
Epithelial-Mesenchymal Transition
1
2016
213
0.030
Why?
Tretinoin
1
2015
122
0.030
Why?
Sequence Analysis, RNA
1
2016
450
0.030
Why?
Benzamides
1
2014
220
0.030
Why?
Transfection
1
2016
936
0.030
Why?
Antigens, CD
1
2016
544
0.030
Why?
Receptor, Notch2
1
2013
15
0.030
Why?
Gonanes
1
2013
27
0.020
Why?
Alphapapillomavirus
1
2013
38
0.020
Why?
Retrospective Studies
1
2011
16373
0.020
Why?
Receptors, CXCR
1
2012
4
0.020
Why?
Erlotinib Hydrochloride
1
2012
69
0.020
Why?
Myeloid Cell Leukemia Sequence 1 Protein
2
2003
40
0.020
Why?
Cyclin D1
1
2012
68
0.020
Why?
Protein Binding
1
2018
2243
0.020
Why?
Disease-Free Survival
1
2014
714
0.020
Why?
Active Transport, Cell Nucleus
2
2003
123
0.020
Why?
Tumor Suppressor Protein p53
1
2016
528
0.020
Why?
Fluorocarbons
1
2014
132
0.020
Why?
Computers
1
2012
68
0.020
Why?
Mice, Inbred C3H
2
2004
269
0.020
Why?
Maximum Tolerated Dose
1
2012
204
0.020
Why?
Niacinamide
1
2012
82
0.020
Why?
Tissue Distribution
1
2012
327
0.020
Why?
Phenylurea Compounds
1
2012
100
0.020
Why?
Injections, Intraperitoneal
2
2001
115
0.020
Why?
Mice, Knockout
3
2003
3065
0.020
Why?
Calcium Signaling
1
2013
249
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
2
2003
236
0.020
Why?
Xanthine Oxidase
2
2001
81
0.020
Why?
Proto-Oncogene Proteins c-myc
1
2012
163
0.020
Why?
Acute Disease
2
2004
1012
0.020
Why?
Cluster Analysis
1
2011
518
0.020
Why?
United States
1
2007
15245
0.020
Why?
Ligands
1
2011
667
0.020
Why?
Vascular Endothelial Growth Factor A
1
2012
550
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
344
0.020
Why?
Survival Rate
1
2014
1973
0.020
Why?
Models, Molecular
1
2014
1603
0.020
Why?
Computational Biology
1
2013
665
0.020
Why?
Tumor Microenvironment
1
2012
707
0.020
Why?
Dose-Response Relationship, Drug
1
2012
2061
0.020
Why?
Adiposity
1
2012
519
0.020
Why?
Mice, Transgenic
2
2003
2178
0.020
Why?
Calcium
1
2013
1191
0.020
Why?
Cell Movement
1
2011
983
0.020
Why?
Oxidative Stress
2
2003
1327
0.020
Why?
Magnetic Resonance Imaging
1
2018
3731
0.010
Why?
Neutrophil Infiltration
1
2004
108
0.010
Why?
Permeability
1
2004
165
0.010
Why?
Transcription Factor AP-1
1
2003
88
0.010
Why?
Phosphotransferases
1
2003
25
0.010
Why?
Class Ib Phosphatidylinositol 3-Kinase
1
2003
3
0.010
Why?
bcl-Associated Death Protein
1
2003
9
0.010
Why?
Aconitate Hydratase
1
2003
17
0.010
Why?
Toll-Like Receptors
1
2004
189
0.010
Why?
JNK Mitogen-Activated Protein Kinases
1
2003
159
0.010
Why?
Algorithms
1
2010
1764
0.010
Why?
Lipid Peroxidation
1
2003
150
0.010
Why?
Reproducibility of Results
1
2010
3343
0.010
Why?
Mice, Mutant Strains
1
2003
306
0.010
Why?
Extracellular Space
1
2003
129
0.010
Why?
Metalloporphyrins
1
2003
103
0.010
Why?
Replication Protein C
1
2001
4
0.010
Why?
Tumor Necrosis Factor alpha-Induced Protein 3
1
2001
12
0.010
Why?
bcl-X Protein
1
2001
45
0.010
Why?
Toll-Like Receptor 4
1
2004
276
0.010
Why?
Biological Transport
1
2003
410
0.010
Why?
Cysteine Endopeptidases
1
2001
74
0.010
Why?
Protein Kinases
1
2003
308
0.010
Why?
CREB-Binding Protein
1
2001
33
0.010
Why?
Transcription Factor RelA
1
2001
85
0.010
Why?
Tungsten
1
2001
30
0.010
Why?
Animal Feed
1
2001
53
0.010
Why?
Immune Sera
1
2000
84
0.010
Why?
Proto-Oncogene Proteins c-fos
1
2001
191
0.010
Why?
Mitogen-Activated Protein Kinase 1
1
2001
183
0.010
Why?
Organ Specificity
1
2000
312
0.010
Why?
Endotoxins
1
2000
220
0.010
Why?
Antioxidants
1
2003
597
0.010
Why?
Protein Biosynthesis
1
2001
444
0.010
Why?
Carrier Proteins
1
2003
746
0.010
Why?
Intubation, Intratracheal
1
2000
290
0.010
Why?
Peptides
1
2001
981
0.010
Why?
Proteins
1
2001
1013
0.010
Why?
Treatment Outcome
1
2010
11194
0.010
Why?
Arcaroli's Networks
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