Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Arcaroli

Concepts (368)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
19
2018
802
2.440
Why?
Xenograft Model Antitumor Assays
21
2024
898
1.440
Why?
Antineoplastic Agents
17
2018
2166
1.320
Why?
Drug Resistance, Neoplasm
7
2016
830
1.010
Why?
Quinazolines
4
2012
250
0.990
Why?
Benzodioxoles
3
2012
128
0.970
Why?
Camptothecin
4
2016
122
0.870
Why?
Receptor, Notch1
3
2015
65
0.840
Why?
Aldehyde Dehydrogenase
6
2017
100
0.840
Why?
Mice, Nude
16
2024
691
0.790
Why?
Haplotypes
4
2012
496
0.730
Why?
Phosphatidylinositol 3-Kinases
10
2018
368
0.700
Why?
Gene Dosage
3
2015
141
0.620
Why?
Wnt Signaling Pathway
5
2024
202
0.620
Why?
Neutrophils
13
2007
1282
0.600
Why?
src-Family Kinases
3
2017
93
0.580
Why?
Amyloid Precursor Protein Secretases
3
2014
79
0.580
Why?
Pancreatic Neoplasms
6
2024
882
0.570
Why?
Endotoxemia
9
2004
87
0.570
Why?
Anilides
2
2018
70
0.570
Why?
Enzyme Inhibitors
5
2016
854
0.560
Why?
Protein Kinase Inhibitors
9
2018
914
0.560
Why?
Biomarkers, Tumor
9
2018
1251
0.530
Why?
Mice
41
2024
18048
0.510
Why?
Acute Lung Injury
2
2011
304
0.500
Why?
Pyridines
4
2018
510
0.490
Why?
Receptors, Notch
2
2015
87
0.490
Why?
Tankyrases
1
2016
13
0.490
Why?
Cell Line, Tumor
21
2024
3469
0.480
Why?
Drug Discovery
1
2016
147
0.470
Why?
Polymorphism, Genetic
3
2007
625
0.460
Why?
NF-kappa B
13
2007
692
0.450
Why?
3' Untranslated Regions
2
2012
149
0.440
Why?
DNA Copy Number Variations
1
2015
176
0.440
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2014
85
0.430
Why?
Proto-Oncogene Proteins c-met
1
2014
73
0.420
Why?
Tetrahydronaphthalenes
1
2013
30
0.400
Why?
Valine
1
2013
77
0.400
Why?
Animals
44
2024
37657
0.380
Why?
Mitogen-Activated Protein Kinases
7
2014
316
0.370
Why?
Lipopolysaccharides
9
2007
889
0.350
Why?
Sepsis
3
2007
616
0.350
Why?
Signal Transduction
17
2018
5144
0.350
Why?
Proto-Oncogene Proteins
8
2018
623
0.330
Why?
Superoxide Dismutase
3
2008
352
0.330
Why?
Urokinase-Type Plasminogen Activator
2
2007
30
0.330
Why?
Cell Proliferation
13
2024
2504
0.310
Why?
Interleukins
1
2011
248
0.310
Why?
Neoplasm Metastasis
4
2016
674
0.300
Why?
Hemorrhage
6
2004
760
0.300
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
97
0.290
Why?
Heterografts
3
2018
134
0.280
Why?
HCT116 Cells
4
2018
80
0.270
Why?
Apoptosis
11
2018
2574
0.270
Why?
SOXB1 Transcription Factors
2
2018
63
0.260
Why?
Carcinoma, Pancreatic Ductal
2
2024
277
0.260
Why?
Azepines
2
2018
97
0.260
Why?
Benzimidazoles
3
2013
182
0.250
Why?
Promoter Regions, Genetic
1
2011
1242
0.250
Why?
Mutation
3
2012
4013
0.250
Why?
Immunoblotting
5
2015
310
0.240
Why?
Receptors, Interleukin-1
1
2006
215
0.230
Why?
Neutrophil Activation
5
2003
87
0.230
Why?
beta Catenin
3
2016
258
0.220
Why?
Oligonucleotide Array Sequence Analysis
6
2015
761
0.220
Why?
Humans
46
2024
141187
0.220
Why?
TOR Serine-Threonine Kinases
4
2018
423
0.220
Why?
Pyrimidines
2
2018
477
0.210
Why?
Intracellular Signaling Peptides and Proteins
2
2006
464
0.200
Why?
Adrenergic alpha-Antagonists
2
2002
34
0.200
Why?
Mice, Inbred BALB C
10
2003
1274
0.200
Why?
Proto-Oncogene Proteins c-akt
8
2018
444
0.200
Why?
Colonic Neoplasms
2
2016
246
0.200
Why?
Proto-Oncogene Proteins c-raf
1
2002
44
0.190
Why?
Adrenergic alpha-Agonists
1
2002
28
0.190
Why?
Genetic Predisposition to Disease
1
2011
2363
0.190
Why?
Neuroimmunomodulation
1
2002
67
0.190
Why?
Female
24
2018
75515
0.190
Why?
ras Proteins
3
2013
148
0.190
Why?
Adrenergic beta-Agonists
1
2002
98
0.180
Why?
Aged
11
2016
24574
0.180
Why?
Adrenergic beta-Antagonists
2
2002
228
0.180
Why?
Middle Aged
12
2016
34434
0.170
Why?
Hemoptysis
1
2000
37
0.170
Why?
Polymorphism, Single Nucleotide
4
2011
2132
0.160
Why?
In Situ Hybridization, Fluorescence
2
2012
310
0.160
Why?
Head and Neck Neoplasms
2
2016
553
0.160
Why?
Carcinoma, Squamous Cell
2
2016
642
0.160
Why?
Cytokines
4
2005
2098
0.150
Why?
Adult
11
2016
39177
0.150
Why?
Cell Transformation, Neoplastic
2
2018
333
0.150
Why?
DNA Topoisomerases, Type II
2
2016
44
0.150
Why?
Male
24
2016
69783
0.150
Why?
CDC2 Protein Kinase
1
2018
31
0.150
Why?
Transplantation, Heterologous
2
2016
193
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
72
0.140
Why?
Oncogene Proteins v-abl
1
2017
5
0.140
Why?
Cyclic AMP Response Element-Binding Protein
4
2003
145
0.140
Why?
Mitogen-Activated Protein Kinase Kinases
3
2010
132
0.140
Why?
p38 Mitogen-Activated Protein Kinases
6
2007
281
0.130
Why?
Dasatinib
1
2017
56
0.130
Why?
Proto-Oncogene Proteins p21(ras)
5
2016
263
0.130
Why?
Immunohistochemistry
5
2017
1737
0.130
Why?
Gene Expression Profiling
4
2018
1764
0.130
Why?
Case-Control Studies
3
2011
3588
0.130
Why?
Angiogenesis Inhibitors
2
2018
230
0.130
Why?
Neovascularization, Pathologic
2
2018
296
0.130
Why?
Intercellular Signaling Peptides and Proteins
2
2015
388
0.130
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.130
Why?
Adenocarcinoma
2
2014
892
0.130
Why?
Receptors, Cell Surface
2
2012
397
0.130
Why?
Aurora Kinase A
1
2016
55
0.120
Why?
Axin Protein
1
2016
19
0.120
Why?
Corynebacterium
1
2017
49
0.120
Why?
Corynebacterium Infections
1
2017
42
0.120
Why?
Antigens, Neoplasm
2
2016
321
0.120
Why?
Neoplasms, Experimental
1
2017
174
0.120
Why?
Transcription Factor 7-Like 2 Protein
1
2016
26
0.120
Why?
Cell Cycle
5
2018
597
0.120
Why?
Neoplastic Stem Cells
2
2018
400
0.120
Why?
Autophagy
1
2018
287
0.120
Why?
Serrate-Jagged Proteins
1
2015
27
0.120
Why?
Genotype
3
2012
1859
0.120
Why?
Jagged-1 Protein
1
2015
23
0.120
Why?
RNA, Small Interfering
2
2015
626
0.120
Why?
RNA, Messenger
5
2016
2828
0.120
Why?
Drug Synergism
2
2014
375
0.120
Why?
Gene Duplication
1
2015
65
0.120
Why?
Neoplasms
3
2016
2741
0.110
Why?
Aged, 80 and over
5
2014
7856
0.110
Why?
Retinaldehyde
1
2015
4
0.110
Why?
HMGB1 Protein
2
2007
50
0.110
Why?
Acetaldehyde
1
2015
17
0.110
Why?
Pyrazoles
1
2018
443
0.110
Why?
Pyrimidinones
1
2015
114
0.110
Why?
Chemokines
5
2003
228
0.110
Why?
Acridines
1
2014
8
0.110
Why?
Neoplasm Transplantation
4
2016
250
0.110
Why?
Chemokine CXCL2
4
2001
42
0.110
Why?
Topoisomerase II Inhibitors
1
2014
26
0.110
Why?
Antineoplastic Combined Chemotherapy Protocols
3
2014
1787
0.110
Why?
Benzazepines
1
2014
35
0.110
Why?
Wnt Proteins
1
2015
136
0.110
Why?
Calcium-Binding Proteins
1
2015
216
0.110
Why?
Pyridones
1
2015
176
0.110
Why?
Respiration, Artificial
2
2011
683
0.110
Why?
Gene Expression Regulation
2
2007
2599
0.100
Why?
Cell Cycle Proteins
1
2018
624
0.100
Why?
Cell Growth Processes
1
2013
53
0.100
Why?
Insulin-Like Growth Factor Binding Protein 2
1
2012
8
0.100
Why?
Cellular Senescence
1
2015
205
0.100
Why?
Tumor Suppressor Proteins
1
2015
325
0.100
Why?
DNA-Binding Proteins
3
2016
1478
0.100
Why?
Random Allocation
1
2013
367
0.090
Why?
Enzyme Activation
6
2003
811
0.090
Why?
Disease Models, Animal
4
2018
4404
0.090
Why?
Aldehyde Dehydrogenase, Mitochondrial
3
2017
23
0.090
Why?
Gene Knockdown Techniques
1
2013
330
0.090
Why?
Molecular Targeted Therapy
1
2015
419
0.090
Why?
Chemokine CXCL12
1
2012
84
0.090
Why?
Receptors, CXCR4
1
2012
88
0.090
Why?
Cyclosporine
1
2013
265
0.090
Why?
Linkage Disequilibrium
2
2012
255
0.090
Why?
Immunoprecipitation
1
2012
154
0.090
Why?
Melanoma
1
2018
772
0.090
Why?
Hydroxamic Acids
1
2011
92
0.090
Why?
Lung Diseases
3
2004
794
0.090
Why?
Lung
8
2004
4134
0.090
Why?
Prognosis
3
2015
4073
0.090
Why?
Peroxidase
2
2002
182
0.090
Why?
Genetic Markers
1
2012
343
0.090
Why?
Drug Design
1
2012
168
0.090
Why?
PTEN Phosphohydrolase
1
2012
163
0.080
Why?
Sirolimus
1
2012
277
0.080
Why?
Genetic Association Studies
1
2012
372
0.080
Why?
Antibodies, Monoclonal, Humanized
2
2013
852
0.080
Why?
Histone Deacetylase Inhibitors
1
2011
210
0.080
Why?
Administration, Oral
1
2012
803
0.080
Why?
Phosphorylation
3
2018
1768
0.080
Why?
Cetuximab
3
2016
105
0.080
Why?
Tumor Necrosis Factor-alpha
4
2004
1250
0.080
Why?
Cell Separation
1
2010
317
0.080
Why?
Membrane Proteins
1
2015
1154
0.070
Why?
G2 Phase Cell Cycle Checkpoints
2
2018
44
0.070
Why?
Gene Expression Regulation, Neoplastic
4
2016
1431
0.070
Why?
Antibodies, Monoclonal
1
2015
1448
0.070
Why?
Models, Statistical
1
2012
671
0.070
Why?
Genetic Variation
2
2012
1000
0.070
Why?
HT29 Cells
2
2018
41
0.060
Why?
Cells, Cultured
6
2007
4208
0.060
Why?
Gene Expression
2
2003
1491
0.060
Why?
Europe
1
2007
410
0.060
Why?
ErbB Receptors
3
2016
610
0.060
Why?
Clinical Trials as Topic
2
2015
1052
0.060
Why?
Flow Cytometry
1
2010
1197
0.060
Why?
Thymine
1
2006
15
0.060
Why?
Genome, Human
1
2008
420
0.060
Why?
Cytosine
1
2006
48
0.060
Why?
Interleukin-1 Receptor-Associated Kinases
1
2006
37
0.060
Why?
Phentolamine
2
2002
18
0.060
Why?
Tumor Burden
2
2018
312
0.060
Why?
Homozygote
1
2006
201
0.060
Why?
MAP Kinase Kinase 2
2
2002
28
0.060
Why?
MicroRNAs
1
2012
689
0.060
Why?
Inflammation Mediators
2
2006
519
0.060
Why?
Translocation, Genetic
1
2006
109
0.060
Why?
Propranolol
2
2002
45
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2007
987
0.060
Why?
Survival Analysis
1
2008
1319
0.060
Why?
MAP Kinase Kinase 1
2
2002
75
0.060
Why?
Cell Nucleus
2
2006
609
0.060
Why?
Spheroids, Cellular
2
2016
77
0.060
Why?
Adolescent
3
2011
22007
0.060
Why?
Introns
1
2006
254
0.060
Why?
Mitogen-Activated Protein Kinase 3
2
2002
150
0.060
Why?
Heat-Shock Proteins
1
2005
142
0.060
Why?
Models, Biological
2
2018
1828
0.060
Why?
Exons
1
2006
353
0.060
Why?
Neoplasm Invasiveness
2
2016
509
0.050
Why?
Bone Marrow Cells
2
2003
325
0.050
Why?
Positron-Emission Tomography
2
2018
310
0.050
Why?
Cause of Death
1
2006
440
0.050
Why?
Shock, Septic
1
2006
210
0.050
Why?
Oxidants
1
2003
112
0.050
Why?
Paclitaxel
1
2024
237
0.050
Why?
Deoxycytidine
1
2024
192
0.050
Why?
Ribosomal Protein S6 Kinases
1
2002
25
0.050
Why?
Brimonidine Tartrate
1
2002
10
0.050
Why?
Models, Genetic
1
2005
591
0.050
Why?
Phenylephrine
1
2002
75
0.050
Why?
Organoids
1
2024
129
0.050
Why?
RNA Interference
2
2016
469
0.050
Why?
Isoenzymes
1
2003
302
0.050
Why?
Quinoxalines
1
2002
67
0.050
Why?
Protein-Tyrosine Kinases
2
2002
431
0.050
Why?
Hydrogen Peroxide
1
2003
339
0.050
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
129
0.050
Why?
Transcription, Genetic
2
2006
1487
0.040
Why?
Lung Neoplasms
1
2015
2560
0.040
Why?
Membrane Glycoproteins
1
2004
501
0.040
Why?
Free Radical Scavengers
1
2001
87
0.040
Why?
Neoplasm Proteins
3
2016
432
0.040
Why?
High Mobility Group Proteins
1
2000
44
0.040
Why?
Imidazoles
1
2001
244
0.040
Why?
MAP Kinase Signaling System
1
2002
325
0.040
Why?
Neutropenia
1
2000
157
0.040
Why?
Interleukin-1
2
2000
968
0.040
Why?
Protein Processing, Post-Translational
1
2002
464
0.040
Why?
Nuclear Proteins
2
2001
712
0.040
Why?
Transcriptome
2
2016
1003
0.040
Why?
Adjuvants, Immunologic
1
2000
238
0.040
Why?
Trans-Activators
1
2001
388
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
24
0.040
Why?
4-Aminobenzoic Acid
1
2018
8
0.040
Why?
Colorado
1
2008
4610
0.040
Why?
Up-Regulation
2
2016
859
0.030
Why?
Biomarkers
1
2008
4174
0.030
Why?
Protein Transport
1
2018
448
0.030
Why?
Retinal Dehydrogenase
1
2016
29
0.030
Why?
Pneumonia
1
2003
656
0.030
Why?
Inhibitory Concentration 50
1
2016
91
0.030
Why?
Hyaluronan Receptors
1
2016
103
0.030
Why?
Blotting, Western
2
2013
1234
0.030
Why?
Tissue Array Analysis
1
2016
52
0.030
Why?
Protein Interaction Maps
1
2016
49
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
122
0.030
Why?
Drug Screening Assays, Antitumor
1
2016
193
0.030
Why?
Mice, Inbred C57BL
4
2015
5887
0.030
Why?
Chromatin Immunoprecipitation
1
2016
136
0.030
Why?
Papillomaviridae
1
2016
133
0.030
Why?
S-Phase Kinase-Associated Proteins
1
2015
20
0.030
Why?
Prospective Studies
1
2007
7739
0.030
Why?
Diphenylamine
1
2014
9
0.030
Why?
Iloprost
1
2015
45
0.030
Why?
Cadherins
1
2016
202
0.030
Why?
Acid Phosphatase
1
2014
20
0.030
Why?
Rhodamines
1
2014
20
0.030
Why?
Gene Expression Regulation, Enzymologic
1
2016
274
0.030
Why?
G2 Phase
1
2014
39
0.030
Why?
Cell Division
1
2016
798
0.030
Why?
Tumor Cells, Cultured
1
2016
959
0.030
Why?
Young Adult
1
2011
13673
0.030
Why?
Inflammation
1
2005
2890
0.030
Why?
Epithelial-Mesenchymal Transition
1
2016
213
0.030
Why?
Tretinoin
1
2015
122
0.030
Why?
Sequence Analysis, RNA
1
2016
450
0.030
Why?
Benzamides
1
2014
216
0.030
Why?
Transfection
1
2016
943
0.030
Why?
Antigens, CD
1
2016
539
0.030
Why?
Receptor, Notch2
1
2013
15
0.030
Why?
Gonanes
1
2013
27
0.030
Why?
Retrospective Studies
1
2011
16273
0.020
Why?
Alphapapillomavirus
1
2013
39
0.020
Why?
Receptors, CXCR
1
2012
4
0.020
Why?
Erlotinib Hydrochloride
1
2012
69
0.020
Why?
Myeloid Cell Leukemia Sequence 1 Protein
2
2003
40
0.020
Why?
Cyclin D1
1
2012
68
0.020
Why?
Protein Binding
1
2018
2239
0.020
Why?
Disease-Free Survival
1
2014
715
0.020
Why?
Active Transport, Cell Nucleus
2
2003
122
0.020
Why?
Tumor Suppressor Protein p53
1
2016
528
0.020
Why?
Computers
1
2012
69
0.020
Why?
Mice, Inbred C3H
2
2004
270
0.020
Why?
Maximum Tolerated Dose
1
2012
206
0.020
Why?
Niacinamide
1
2012
82
0.020
Why?
Tissue Distribution
1
2012
330
0.020
Why?
Phenylurea Compounds
1
2012
95
0.020
Why?
Injections, Intraperitoneal
2
2001
114
0.020
Why?
Mice, Knockout
3
2003
3068
0.020
Why?
Calcium Signaling
1
2013
250
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
2
2003
236
0.020
Why?
Xanthine Oxidase
2
2001
81
0.020
Why?
Proto-Oncogene Proteins c-myc
1
2012
162
0.020
Why?
Acute Disease
2
2004
1008
0.020
Why?
Cluster Analysis
1
2011
521
0.020
Why?
United States
1
2007
15220
0.020
Why?
Ligands
1
2011
667
0.020
Why?
Vascular Endothelial Growth Factor A
1
2012
550
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
344
0.020
Why?
Survival Rate
1
2014
1970
0.020
Why?
Models, Molecular
1
2014
1603
0.020
Why?
Computational Biology
1
2013
661
0.020
Why?
Tumor Microenvironment
1
2012
692
0.020
Why?
Dose-Response Relationship, Drug
1
2012
2064
0.020
Why?
Adiposity
1
2012
521
0.020
Why?
Mice, Transgenic
2
2003
2180
0.020
Why?
Calcium
1
2013
1187
0.020
Why?
Cell Movement
1
2011
990
0.020
Why?
Oxidative Stress
2
2003
1330
0.020
Why?
Magnetic Resonance Imaging
1
2018
3709
0.020
Why?
Neutrophil Infiltration
1
2004
108
0.010
Why?
Permeability
1
2004
166
0.010
Why?
Transcription Factor AP-1
1
2003
88
0.010
Why?
Phosphotransferases
1
2003
24
0.010
Why?
Class Ib Phosphatidylinositol 3-Kinase
1
2003
3
0.010
Why?
bcl-Associated Death Protein
1
2003
9
0.010
Why?
Aconitate Hydratase
1
2003
17
0.010
Why?
Toll-Like Receptors
1
2004
189
0.010
Why?
JNK Mitogen-Activated Protein Kinases
1
2003
159
0.010
Why?
Algorithms
1
2010
1763
0.010
Why?
Lipid Peroxidation
1
2003
150
0.010
Why?
Mice, Mutant Strains
1
2003
309
0.010
Why?
Reproducibility of Results
1
2010
3348
0.010
Why?
Extracellular Space
1
2003
129
0.010
Why?
Metalloporphyrins
1
2003
105
0.010
Why?
Replication Protein C
1
2001
4
0.010
Why?
Tumor Necrosis Factor alpha-Induced Protein 3
1
2001
11
0.010
Why?
bcl-X Protein
1
2001
43
0.010
Why?
Toll-Like Receptor 4
1
2004
276
0.010
Why?
Biological Transport
1
2003
407
0.010
Why?
Cysteine Endopeptidases
1
2001
74
0.010
Why?
Protein Kinases
1
2003
308
0.010
Why?
CREB-Binding Protein
1
2001
33
0.010
Why?
Transcription Factor RelA
1
2001
85
0.010
Why?
Tungsten
1
2001
30
0.010
Why?
Animal Feed
1
2001
54
0.010
Why?
Immune Sera
1
2000
84
0.010
Why?
Proto-Oncogene Proteins c-fos
1
2001
191
0.010
Why?
Mitogen-Activated Protein Kinase 1
1
2001
183
0.010
Why?
Organ Specificity
1
2000
312
0.010
Why?
Endotoxins
1
2000
220
0.010
Why?
Antioxidants
1
2003
595
0.010
Why?
Protein Biosynthesis
1
2001
444
0.010
Why?
Carrier Proteins
1
2003
740
0.010
Why?
Intubation, Intratracheal
1
2000
286
0.010
Why?
Peptides
1
2001
978
0.010
Why?
Proteins
1
2001
1010
0.010
Why?
Treatment Outcome
1
2010
11120
0.010
Why?
Arcaroli's Networks
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