Replication Protein C
"Replication Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.
Descriptor ID |
D051818
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MeSH Number(s) |
D08.811.277.040.013.500.438 D08.811.277.040.025.024.438 D12.776.157.025.750.438 D12.776.260.702
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Replication Protein C".
Below are MeSH descriptors whose meaning is more specific than "Replication Protein C".
This graph shows the total number of publications written about "Replication Protein C" by people in this website by year, and whether "Replication Protein C" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2006 | 2 | 0 | 2 |
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Below are the most recent publications written about "Replication Protein C" by people in Profiles.
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Johnson A, Yao NY, Bowman GD, Kuriyan J, O'Donnell M. The replication factor C clamp loader requires arginine finger sensors to drive DNA binding and proliferating cell nuclear antigen loading. J Biol Chem. 2006 Nov 17; 281(46):35531-43.
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Yao NY, Johnson A, Bowman GD, Kuriyan J, O'Donnell M. Mechanism of proliferating cell nuclear antigen clamp opening by replication factor C. J Biol Chem. 2006 Jun 23; 281(25):17528-17539.
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Kupfner JG, Arcaroli JJ, Yum HK, Nadler SG, Yang KY, Abraham E. Role of NF-kappaB in endotoxemia-induced alterations of lung neutrophil apoptosis. J Immunol. 2001 Dec 15; 167(12):7044-51.
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Lossie AC, Haugen BR, Wood WM, Camper SA, Gordon DF. Chromosomal localization of the large subunit of mouse replication factor C in the mouse and human. Mamm Genome. 1995 Jan; 6(1):58-9.
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