 Aconitate Hydratase
"Aconitate Hydratase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the reversible hydration of cis-aconitate to yield citrate or isocitrate. It is one of the citric acid cycle enzymes. EC 4.2.1.3.
| Descriptor ID |
D000154
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| MeSH Number(s) |
D08.811.520.241.300.050
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| Concept/Terms |
Aconitate Hydratase- Aconitate Hydratase
- Hydratase, Aconitate
- Citrate Hydrolyase
- Hydrolyase, Citrate
- Isocitrate Hydro-Lyase
- Hydro-Lyase, Isocitrate
- Isocitrate Hydro Lyase
- Aconitase
- Citrate Hydro-Lyase
- Citrate Hydro Lyase
- Hydro-Lyase, Citrate
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Below are MeSH descriptors whose meaning is more general than "Aconitate Hydratase".
Below are MeSH descriptors whose meaning is more specific than "Aconitate Hydratase".
This graph shows the total number of publications written about "Aconitate Hydratase" by people in this website by year, and whether "Aconitate Hydratase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aconitate Hydratase" by people in Profiles.
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Janssen RC, Boyle KE. Microplate Assays for Spectrophotometric Measurement of Mitochondrial Enzyme Activity. Methods Mol Biol. 2019; 1978:355-368.
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Li Y, Polak U, Bhalla AD, Rozwadowska N, Butler JS, Lynch DR, Dent SYR, Napierala M. Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia. Mol Ther. 2015 Jun; 23(6):1055-1065.
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Jones-Carson J, Laughlin JR, Stewart AL, Voskuil MI, V?zquez-Torres A. Nitric oxide-dependent killing of aerobic, anaerobic and persistent Burkholderia pseudomallei. Nitric Oxide. 2012 Jun 30; 27(1):25-31.
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Liang LP, Waldbaum S, Rowley S, Huang TT, Day BJ, Patel M. Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin. Neurobiol Dis. 2012 Mar; 45(3):1068-76.
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Cantu D, Schaack J, Patel M. Oxidative inactivation of mitochondrial aconitase results in iron and H2O2-mediated neurotoxicity in rat primary mesencephalic cultures. PLoS One. 2009 Sep 18; 4(9):e7095.
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Sheng H, Yang W, Fukuda S, Tse HM, Paschen W, Johnson K, Batinic-Haberle I, Crapo JD, Pearlstein RD, Piganelli J, Warner DS. Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat. Free Radic Biol Med. 2009 Oct 01; 47(7):917-23.
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Jones-Carson J, Laughlin J, Hamad MA, Stewart AL, Voskuil MI, V?zquez-Torres A. Inactivation of [Fe-S] metalloproteins mediates nitric oxide-dependent killing of Burkholderia mallei. PLoS One. 2008 Apr 09; 3(4):e1976.
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Velsor LW, Kariya C, Kachadourian R, Day BJ. Mitochondrial oxidative stress in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice. Am J Respir Cell Mol Biol. 2006 Nov; 35(5):579-86.
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Leinenweber SB, Sheng H, Lynch JR, Wang H, Batinic-Haberle I, Laskowitz DT, Crapo JD, Pearlstein RD, Warner DS. Effects of a manganese (III) porphyrin catalytic antioxidant in a mouse closed head injury model. Eur J Pharmacol. 2006 Feb 15; 531(1-3):126-32.
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Sauer SW, Okun JG, Schwab MA, Crnic LR, Hoffmann GF, Goodman SI, Koeller DM, K?lker S. Bioenergetics in glutaryl-coenzyme A dehydrogenase deficiency: a role for glutaryl-coenzyme A. J Biol Chem. 2005 Jun 10; 280(23):21830-6.
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