 Cyclin D1
"Cyclin D1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.
| Descriptor ID |
D019938
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| MeSH Number(s) |
D12.644.360.262.150.100 D12.776.167.218.150.100 D12.776.476.262.150.100 D12.776.624.664.700.100
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| Concept/Terms |
Cyclin D1- Cyclin D1
- Proto-Oncogene Products bcl-1
- Proto Oncogene Products bcl 1
- Proto-Oncogene Protein bcl-1
- Proto Oncogene Protein bcl 1
- bcl-1, Proto-Oncogene Protein
- bcl-1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl-1
- bcl 1 Proto Oncogene Proteins
- CCND1 Protein
- PRAD1 Protein
- bcl-1 Proto-Oncogene Products
- Proto-Oncogene Products, bcl-1
- bcl 1 Proto Oncogene Products
- bcl1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl1
- bcl1 Proto Oncogene Proteins
- Proto-Oncogene Proteins c-bcl-1
- Proto Oncogene Proteins c bcl 1
- c-bcl-1, Proto-Oncogene Proteins
- c-bcl-1 Proteins
- c bcl 1 Proteins
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Below are MeSH descriptors whose meaning is more general than "Cyclin D1".
Below are MeSH descriptors whose meaning is more specific than "Cyclin D1".
This graph shows the total number of publications written about "Cyclin D1" by people in this website by year, and whether "Cyclin D1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2005 | 0 | 5 | 5 | | 2006 | 1 | 2 | 3 | | 2007 | 1 | 2 | 3 | | 2008 | 1 | 4 | 5 | | 2009 | 1 | 3 | 4 | | 2010 | 0 | 5 | 5 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 3 | 4 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 1 | 1 | | 2017 | 3 | 2 | 5 | | 2019 | 1 | 2 | 3 | | 2020 | 0 | 1 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclin D1" by people in Profiles.
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Nangia V, Ashraf H, Marikar N, Passanisi VJ, Ill CR, Spencer SL. MAPK and mTORC1 signaling converge to drive cyclin D1 protein production to enable cell cycle reentry in melanoma persister cells. Sci Signal. 2025 Sep 02; 18(902):eadw3231.
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Croft J, Ellis S, Sherborne AL, Sharp K, Price A, Jenner MW, Drayson MT, Owen RG, Chown S, Lindsay J, Karunanithi K, Hunter H, Gregory WM, Davies FE, Morgan GJ, Cook G, Atanesyan L, Savola S, Cairns DA, Jackson G, Houlston RS, Kaiser MF. Copy number evolution and its relationship with patient outcome-an analysis of 178 matched presentation-relapse tumor pairs from the Myeloma XI trial. Leukemia. 2021 07; 35(7):2043-2053.
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Lu S, Weiser-Evans MCM. Nuclear Focal Adhesion Kinase. Circ Res. 2019 07 05; 125(2):167-169.
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Lewis R, Li YD, Hoffman L, Hashizume R, Gravohac G, Rice G, Wadhwani NR, Jie C, Pundy T, Mania-Farnell B, Mayanil CS, Soares MB, Lei T, James CD, Foreman NK, Tomita T, Xi G. Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas. Neoplasia. 2019 06; 21(6):505-515.
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Rigby C, Deep G, Jain A, Orlicky DJ, Agarwal C, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma. Mol Carcinog. 2019 07; 58(7):1260-1271.
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Romagnolo DF, Donovan MG, Doetschman TC, Selmin OI. n-6 Linoleic Acid Induces Epigenetics Alterations Associated with Colonic Inflammation and Cancer. Nutrients. 2019 Jan 15; 11(1).
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Saemi N, Khoshnevis J, Akbari ME, Meysamie A, Korourian A, Gholizadeh B, Larijani L, Moradi A, Baikpour M, Baikpour M, Zham H. Evaluating the Correlation Between the Survival Rate of Patients with Esophageal Squamous Cell Carcinoma and Expression of p53 and Cyclin D1 Biomarkers Along with Other Prognostic Factors. J Gastrointest Cancer. 2018 Mar; 49(1):35-40.
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Li Y, Jin K, Bunker E, Zhang X, Luo X, Liu X, Hao B. Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):319-324.
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Kar A, Liu B, Gutierrez-Hartmann A. ESE-1 Knockdown Attenuates Growth in Trastuzumab-resistant HER2+ Breast Cancer Cells. Anticancer Res. 2017 12; 37(12):6583-6591.
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Gookin S, Min M, Phadke H, Chung M, Moser J, Miller I, Carter D, Spencer SL. A map of protein dynamics during cell-cycle progression and cell-cycle exit. PLoS Biol. 2017 Sep; 15(9):e2003268.
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