 Cadherins
"Cadherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.
| Descriptor ID |
D015820
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| MeSH Number(s) |
D12.776.395.550.200.200 D12.776.543.550.200.200 D23.050.301.350.200
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| Concept/Terms |
P-Cadherins- P-Cadherins
- P Cadherins
- P-Cadherin
- P Cadherin
- Placental Cadherins
- Cadherins, Placental
- Cadherin-3
- Cadherin 3
E-Cadherins- E-Cadherins
- E Cadherins
- Uvomorulin
- Epithelial-Cadherins
- Epithelial Cadherins
- Cadherin-1
- Cadherin 1
- E-Cadherin
- E Cadherin
N-Cadherins- N-Cadherins
- N Cadherins
- N-Cadherin
- N Cadherin
- Neural Cadherins
- Cadherins, Neural
- Cadherin-2
- Cadherin 2
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Below are MeSH descriptors whose meaning is more general than "Cadherins".
Below are MeSH descriptors whose meaning is more specific than "Cadherins".
This graph shows the total number of publications written about "Cadherins" by people in this website by year, and whether "Cadherins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 1 | 3 | | 1995 | 3 | 1 | 4 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 3 | 1 | 4 | | 2001 | 1 | 0 | 1 | | 2003 | 2 | 3 | 5 | | 2004 | 2 | 2 | 4 | | 2005 | 1 | 3 | 4 | | 2006 | 3 | 3 | 6 | | 2007 | 3 | 1 | 4 | | 2008 | 1 | 5 | 6 | | 2009 | 1 | 3 | 4 | | 2010 | 1 | 6 | 7 | | 2011 | 5 | 6 | 11 | | 2012 | 1 | 3 | 4 | | 2013 | 3 | 1 | 4 | | 2014 | 5 | 1 | 6 | | 2015 | 1 | 4 | 5 | | 2016 | 4 | 6 | 10 | | 2017 | 2 | 1 | 3 | | 2018 | 3 | 3 | 6 | | 2019 | 4 | 0 | 4 | | 2020 | 2 | 1 | 3 | | 2021 | 3 | 1 | 4 | | 2022 | 1 | 1 | 2 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cadherins" by people in Profiles.
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Leckband D, Schwartz DK, Wu Y. Computational and experimental approaches to quantify protein binding interactions under confinement. Biophys J. 2024 02 20; 123(4):424-434.
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Saemundsson SA, Ganguly S, Curry SD, Goodwin AP, Cha JN. Controlling Cell Organization in 3D Coculture Spheroids Using DNA Interactions. ACS Biomater Sci Eng. 2023 06 12; 9(6):3185-3192.
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Lai D, Gade M, Yang E, Koh HY, Lu J, Walley NM, Buckley AF, Sands TT, Akman CI, Mikati MA, McKhann GM, Goldman JE, Canoll P, Alexander AL, Park KL, Von Allmen GK, Rodziyevska O, Bhattacharjee MB, Lidov HGW, Vogel H, Grant GA, Porter BE, Poduri AH, Crino PB, Heinzen EL. Somatic variants in diverse genes leads to a spectrum of focal cortical malformations. Brain. 2022 08 27; 145(8):2704-2720.
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Rao VV, Wechsler ME, Cravens E, Wojda SJ, Caldwell AS, Kirkpatrick BE, Donahue SW, Anseth KS. Granular PEG hydrogels mediate osteoporotic MSC clustering via N-cadherin influencing the pro-resorptive bias of their secretory profile. Acta Biomater. 2022 06; 145:77-87.
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Mondal K, Takahashi H, Cole J, Del Mar NA, Li C, Stephenson DJ, Allegood J, Cowart LA, Chalfant CE, Reiner A, Mandal N. Systemic Elevation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Is Associated with Protection against Visual, Motor, and Emotional Deficits in Mice following Closed-Head Mild Traumatic Brain Injury. Mol Neurobiol. 2021 Nov; 58(11):5564-5580.
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Gautam D, Pedler MG, Nair DP, Petrash JM. Nanogel-Facilitated In-Situ Delivery of a Cataract Inhibitor. Biomolecules. 2021 08 04; 11(8).
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Thompson CJ, Vu VH, Leckband DE, Schwartz DK. Cadherin cis and trans interactions are mutually cooperative. Proc Natl Acad Sci U S A. 2021 03 09; 118(10).
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Lee W, Frederick RO, Tonelli M, Palmenberg AC. Solution NMR Determination of the CDHR3 Rhinovirus-C Binding Domain, EC1. Viruses. 2021 01 22; 13(2).
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Daulagala AC, Yost J, Yeganegi A, Richardson WJ, Yost MJ, Kourtidis A. A Simple Method to Test Mechanical Strain on Epithelial Cell Monolayers Using a 3D-Printed Stretcher. Methods Mol Biol. 2021; 2367:235-247.
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Thompson CJ, Su Z, Vu VH, Wu Y, Leckband DE, Schwartz DK. Cadherin clusters stabilized by a combination of specific and nonspecific cis-interactions. Elife. 2020 09 02; 9.
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