 Cadherins
"Cadherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.
| Descriptor ID |
D015820
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| MeSH Number(s) |
D12.776.395.550.200.200 D12.776.543.550.200.200 D23.050.301.350.200
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| Concept/Terms |
P-Cadherins- P-Cadherins
- P Cadherins
- P-Cadherin
- P Cadherin
- Placental Cadherins
- Cadherins, Placental
- Cadherin-3
- Cadherin 3
E-Cadherins- E-Cadherins
- E Cadherins
- Uvomorulin
- Epithelial-Cadherins
- Epithelial Cadherins
- Cadherin-1
- Cadherin 1
- E-Cadherin
- E Cadherin
N-Cadherins- N-Cadherins
- N Cadherins
- N-Cadherin
- N Cadherin
- Neural Cadherins
- Cadherins, Neural
- Cadherin-2
- Cadherin 2
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Below are MeSH descriptors whose meaning is more general than "Cadherins".
Below are MeSH descriptors whose meaning is more specific than "Cadherins".
This graph shows the total number of publications written about "Cadherins" by people in this website by year, and whether "Cadherins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 3 | 1 | 4 | | 2003 | 1 | 3 | 4 | | 2004 | 2 | 2 | 4 | | 2005 | 1 | 3 | 4 | | 2006 | 3 | 3 | 6 | | 2007 | 3 | 1 | 4 | | 2008 | 1 | 5 | 6 | | 2009 | 1 | 3 | 4 | | 2010 | 1 | 6 | 7 | | 2011 | 5 | 6 | 11 | | 2012 | 1 | 3 | 4 | | 2013 | 3 | 2 | 5 | | 2014 | 5 | 1 | 6 | | 2015 | 2 | 5 | 7 | | 2016 | 5 | 6 | 11 | | 2017 | 3 | 1 | 4 | | 2018 | 4 | 4 | 8 | | 2019 | 5 | 0 | 5 | | 2020 | 3 | 3 | 6 | | 2021 | 6 | 2 | 8 | | 2022 | 2 | 3 | 5 | | 2023 | 1 | 5 | 6 | | 2024 | 4 | 1 | 5 | | 2025 | 4 | 0 | 4 |
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Below are the most recent publications written about "Cadherins" by people in Profiles.
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Gallanis AF, Gamble LA, Oguz C, Samaranayake SG, Kedei N, Hernandez MO, Wong M, Tillo D, Green BL, McClelland P, Bowden C, Gullo I, Raffeld M, Xi L, Kelly M, Miettinen M, Quezado M, Kim SA, Blakely AM, Lack J, Heller T, Hernandez JM, Davis JL. Spatial Analysis of Hereditary Diffuse Gastric Cancer Reveals Indolent Phenotype of Signet Ring Cell Precursors. Mol Cancer Res. 2025 Aug 04; 23(8):699-709.
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Fasaye GA, Calzone K, Travis E, Gallanis AF, Gamble L, Davis JL. Association between proband characteristics and CDH1 cascade genetic testing uptake in at-risk relatives. J Genet Couns. 2025 Jun; 34(3):e70011.
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Schloss SS, Marshall ZQ, Santistevan NJ, Gjorcheska S, Stenzel A, Barske L, Nelson JC. Cadherin-16 regulates acoustic sensory gating in zebrafish through endocrine signaling. PLoS Biol. 2025 May; 23(5):e3003164.
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So RJ, Collins SL, Chan-Li Y, Lina I, Gelbard A, Motz KM, Hillel AT. Localized Knockout of E-Cadherin in Subglottic Mucosa Increases Fibrosis. Otolaryngol Head Neck Surg. 2025 Jun; 172(6):2003-2008.
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Gallanis AF, Bowden C, Lopez R, Gamble LA, Samaranayake SG, Payne C, Snyder D, Fasaye GA, Joyce S, Broesamle R, Miao N, Miettinen M, Quezado M, Kim SA, Korman L, Heller T, Blakely AM, Hernandez JM, Davis JL. Lessons learned from 150 total gastrectomies for prevention of cancer. J Gastrointest Surg. 2025 Jan; 29(1):101889.
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Ryan CE, Fasaye GA, Gallanis AF, Gamble LA, McClelland PH, Duemler A, Samaranayake SG, Blakely AM, Drogan CM, Kingham K, Patel D, Rodgers-Fouche L, Siegel A, Kupfer SS, Ford JM, Chung DC, Dowty JG, Sampson J, Davis JL. Germline CDH1 Variants and Lifetime Cancer Risk. JAMA. 2024 09 03; 332(9):722-729.
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Kiseljak-Vassiliades K, Lipe K, Turin CG, Fishbein L, Costello JC, Kerr JM, Holmstoen TB, Youssef AS, Lillehei KO, Kleinschmidt-DeMasters BK, Wierman ME. E-cadherin expression and gene expression profiles in corticotroph pituitary neuroendocrine tumor subtypes. J Neuropathol Exp Neurol. 2024 Jun 20; 83(7):586-595.
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Shirai R, Biebighauser T, Walker D, Oviedo J, Nelson-Taylor S, Bodlak A, Porfilio T, Oike N, Goodspeed A, Hayashi M. Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-?-catenin pathway activation in Ewing sarcoma. PLoS One. 2024; 19(6):e0305490.
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Leckband D, Schwartz DK, Wu Y. Computational and experimental approaches to quantify protein binding interactions under confinement. Biophys J. 2024 02 20; 123(4):424-434.
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Green BL, Gamble LA, Diggs LP, Nousome D, Patterson JC, Joughin BA, Gasmi B, Lux SC, Samaranayake SG, Miettinen M, Quezado M, Hernandez JM, Yaffe MB, Davis JL. Early Immune Changes Support Signet Ring Cell Dormancy in CDH1-Driven Hereditary Diffuse Gastric Carcinogenesis. Mol Cancer Res. 2023 12 01; 21(12):1356-1365.
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