 Spheroids, Cellular
"Spheroids, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue-specific functions. The ability to form spheroids is a characteristic trait of CULTURED TUMOR CELLS derived from solid TUMORS. Cells from normal tissues can also form spheroids. They represent an in-vitro model for studies of the biology of both normal and malignant cells. (From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4)
| Descriptor ID |
D018874
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| MeSH Number(s) |
A11.251.800
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| Concept/Terms |
Spheroids, Cellular- Spheroids, Cellular
- Cellular Spheroid
- Cellular Spheroids
- Spheroid, Cellular
- Multicellular Spheroids
- Multicellular Spheroid
- Spheroid, Multicellular
- Spheroids, Multicellular
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Below are MeSH descriptors whose meaning is more general than "Spheroids, Cellular".
Below are MeSH descriptors whose meaning is more specific than "Spheroids, Cellular".
This graph shows the total number of publications written about "Spheroids, Cellular" by people in this website by year, and whether "Spheroids, Cellular" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 2 | 3 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 3 | 4 | | 2016 | 0 | 1 | 1 | | 2017 | 2 | 3 | 5 | | 2019 | 0 | 3 | 3 | | 2020 | 1 | 1 | 2 | | 2021 | 2 | 1 | 3 | | 2022 | 0 | 1 | 1 | | 2023 | 1 | 0 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spheroids, Cellular" by people in Profiles.
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Caprio ND, Davidson MD, Daly AC, Burdick JA. Injectable MSC Spheroid and Microgel Granular Composites for Engineering Tissue. Adv Mater. 2024 Apr; 36(14):e2312226.
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Saemundsson SA, Ganguly S, Curry SD, Goodwin AP, Cha JN. Controlling Cell Organization in 3D Coculture Spheroids Using DNA Interactions. ACS Biomater Sci Eng. 2023 06 12; 9(6):3185-3192.
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Caprio ND, Burdick JA. Engineered biomaterials to guide spheroid formation, function, and fabrication into 3D tissue constructs. Acta Biomater. 2023 Jul 15; 165:4-18.
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Ganguly S, Roy S, Goodwin AP, Cha JN. Generation of 3D cellular spheroids using DNA modified cell receptors and programmable DNA interactions. Biomater Sci. 2021 Nov 23; 9(23):7911-7920.
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Daly AC, Davidson MD, Burdick JA. 3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels. Nat Commun. 2021 02 02; 12(1):753.
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Mukherjee N, Lambert KA, Norris DA, Shellman YG. Enrichment of Melanoma Stem-Like Cells via Sphere Assays. Methods Mol Biol. 2021; 2265:185-199.
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Yang C, Luo J, Polunas M, Bosnjak N, Chueng SD, Chadwick M, Sabaawy HE, Chester SA, Lee KB, Lee H. 4D-Printed Transformable Tube Array for High-Throughput 3D Cell Culture and Histology. Adv Mater. 2020 Oct; 32(40):e2004285.
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Esquer H, Zhou Q, Abraham AD, LaBarbera DV. Advanced High-Content-Screening Applications of Clonogenicity in Cancer. SLAS Discov. 2020 08; 25(7):734-743.
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Tucker LH, Hamm GR, Sargeant RJE, Goodwin RJA, Mackay CL, Campbell CJ, Clarke DJ. Untargeted Metabolite Mapping in 3D Cell Culture Models Using High Spectral Resolution FT-ICR Mass Spectrometry Imaging. Anal Chem. 2019 08 06; 91(15):9522-9529.
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Berger AJ, Renner CM, Hale I, Yang X, Ponik SM, Weisman PS, Masters KS, Kreeger PK. Scaffold stiffness influences breast cancer cell invasion via EGFR-linked Mena upregulation and matrix remodeling. Matrix Biol. 2020 01; 85-86:80-93.
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