Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Charles Hoeffer

Concepts (325)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Muscle Proteins
5
2026
243
2.520
Why?
Intracellular Signaling Peptides and Proteins
6
2026
457
2.190
Why?
Long-Term Potentiation
10
2017
199
1.790
Why?
Proto-Oncogene Proteins c-akt
4
2025
440
1.780
Why?
Down Syndrome
5
2026
525
1.590
Why?
Neuronal Plasticity
12
2017
305
1.200
Why?
Brain
6
2026
2969
1.140
Why?
Protein Biosynthesis
5
2021
452
1.110
Why?
Astrocytes
3
2025
228
1.060
Why?
Sleep
3
2026
889
1.010
Why?
Tauopathies
4
2026
14
0.960
Why?
Hippocampus
11
2017
973
0.960
Why?
Behavior, Animal
9
2023
520
0.950
Why?
Neurons
11
2026
1652
0.940
Why?
Memory
6
2021
297
0.930
Why?
Nicotinic Agonists
2
2025
135
0.930
Why?
Nicotine
2
2025
331
0.840
Why?
Calcium-Binding Proteins
3
2022
221
0.820
Why?
Alzheimer Disease
4
2022
630
0.810
Why?
Epistasis, Genetic
2
2023
64
0.770
Why?
tau Proteins
5
2026
105
0.740
Why?
Mice
36
2026
18355
0.720
Why?
Chronobiology Disorders
1
2022
16
0.720
Why?
Amyotrophic Lateral Sclerosis
1
2023
96
0.720
Why?
Sleep Wake Disorders
1
2026
314
0.700
Why?
DNA-Binding Proteins
5
2023
1482
0.680
Why?
Animals
46
2026
38097
0.660
Why?
Mice, Knockout
17
2025
3130
0.660
Why?
Spatial Memory
1
2020
27
0.650
Why?
Dendritic Spines
2
2021
70
0.630
Why?
Anxiety
6
2026
1122
0.630
Why?
Mice, Transgenic
11
2026
2191
0.610
Why?
Extinction, Psychological
1
2020
92
0.600
Why?
Mice, Inbred C57BL
14
2026
5992
0.600
Why?
Interleukin-17
2
2017
120
0.590
Why?
Synapses
9
2017
439
0.590
Why?
Signal Transduction
11
2016
5223
0.560
Why?
Aging
2
2022
1973
0.550
Why?
TOR Serine-Threonine Kinases
6
2014
456
0.550
Why?
Disease Models, Animal
14
2026
4568
0.520
Why?
Basolateral Nuclear Complex
1
2017
11
0.500
Why?
Eukaryotic Initiation Factor-4E
2
2021
32
0.500
Why?
Memory, Long-Term
2
2020
12
0.500
Why?
Memory Consolidation
1
2017
14
0.500
Why?
Transcriptome
1
2023
1042
0.490
Why?
Fragile X Syndrome
3
2012
119
0.470
Why?
Nerve Degeneration
1
2015
49
0.460
Why?
Genome-Wide Association Study
4
2023
1430
0.440
Why?
Autism Spectrum Disorder
2
2017
423
0.420
Why?
Up-Regulation
2
2021
848
0.420
Why?
Gene Expression Regulation
6
2017
2601
0.420
Why?
Interneurons
2
2026
125
0.420
Why?
Protein Synthesis Inhibitors
2
2012
48
0.420
Why?
Sensory Gating
2
2013
44
0.400
Why?
Fluoxetine
1
2013
56
0.380
Why?
Eukaryotic Initiation Factor-4F
1
2012
2
0.380
Why?
GABAergic Neurons
1
2013
37
0.380
Why?
Gene Expression
1
2017
1478
0.370
Why?
Protein Phosphatase 1
2
2013
32
0.360
Why?
Receptors, Nicotinic
3
2025
327
0.340
Why?
Mental Disorders
1
2020
1169
0.340
Why?
Eukaryotic Initiation Factor-4G
1
2011
6
0.340
Why?
Mitochondria
2
2015
992
0.330
Why?
Corticosterone
1
2012
241
0.330
Why?
eIF-2 Kinase
2
2024
28
0.310
Why?
Phosphorylation
10
2026
1708
0.310
Why?
Wakefulness
2
2024
170
0.310
Why?
Adaptor Proteins, Signal Transducing
2
2012
426
0.300
Why?
Tacrolimus Binding Protein 1A
1
2008
10
0.290
Why?
Raptors
1
2008
5
0.290
Why?
Motor Activity
3
2022
718
0.290
Why?
Male
23
2026
73003
0.290
Why?
Feces
1
2012
496
0.280
Why?
Maze Learning
5
2014
105
0.270
Why?
Protein Isoforms
2
2020
399
0.260
Why?
Receptors, Metabotropic Glutamate
4
2014
37
0.260
Why?
Protein Kinases
2
2008
312
0.260
Why?
Circadian Rhythm
1
2012
513
0.260
Why?
Memory Disorders
3
2015
197
0.250
Why?
Receptors, AMPA
3
2026
147
0.250
Why?
Fear
3
2008
368
0.250
Why?
Nervous System Diseases
1
2009
286
0.240
Why?
Polymorphism, Single Nucleotide
4
2023
2181
0.240
Why?
RNA, Messenger
4
2017
2805
0.240
Why?
Analysis of Variance
4
2017
1300
0.230
Why?
KCNQ2 Potassium Channel
1
2025
15
0.230
Why?
4-Aminopyridine
1
2025
30
0.230
Why?
Potassium Channel Blockers
1
2025
47
0.230
Why?
Protein Aggregation, Pathological
1
2025
18
0.230
Why?
Electroencephalography
2
2026
563
0.220
Why?
Neocortex
1
2025
49
0.220
Why?
Phenotype
5
2023
3170
0.220
Why?
Hydrazones
2
2017
26
0.220
Why?
Glial Fibrillary Acidic Protein
1
2025
122
0.220
Why?
Anti-Anxiety Agents
2
2023
48
0.210
Why?
In Vitro Techniques
7
2014
1049
0.210
Why?
Nucleus Accumbens
1
2026
135
0.210
Why?
Drosophila melanogaster
2
2003
239
0.210
Why?
Thiazoles
2
2017
142
0.210
Why?
Cyclic GMP-Dependent Protein Kinase Type II
2
2014
2
0.200
Why?
Coculture Techniques
1
2024
247
0.200
Why?
Mutation
3
2016
4090
0.200
Why?
Diazepam
1
2023
33
0.200
Why?
Cyclic AMP Response Element-Binding Protein
3
2013
146
0.200
Why?
Gliosis
1
2023
30
0.190
Why?
RNA, Double-Stranded
1
2023
51
0.190
Why?
Cells, Cultured
4
2025
4151
0.190
Why?
Vesicular Transport Proteins
1
2003
85
0.190
Why?
Nerve Net
1
2025
286
0.180
Why?
Rats, Sprague-Dawley
4
2021
2525
0.180
Why?
Long-Term Synaptic Depression
3
2014
49
0.180
Why?
Suprachiasmatic Nucleus
1
2022
19
0.180
Why?
Sleep Deprivation
1
2024
206
0.180
Why?
Pyramidal Cells
2
2025
80
0.170
Why?
Neural Inhibition
2
2017
178
0.170
Why?
Multifactorial Inheritance
1
2023
209
0.170
Why?
Prefrontal Cortex
2
2017
336
0.170
Why?
Nerve Tissue Proteins
3
2024
592
0.170
Why?
Induced Pluripotent Stem Cells
1
2024
273
0.170
Why?
Cerebral Cortex
2
2016
474
0.170
Why?
Epilepsy
1
2025
390
0.160
Why?
Spatial Behavior
1
2020
24
0.160
Why?
Motor Neurons
1
2023
236
0.160
Why?
Gene Regulatory Networks
1
2023
318
0.160
Why?
Neurodegenerative Diseases
1
2022
143
0.160
Why?
Spinal Cord
1
2023
382
0.160
Why?
Calcineurin
2
2013
105
0.160
Why?
Female
12
2026
79035
0.160
Why?
Cell Nucleus
1
2003
588
0.150
Why?
Anxiety Disorders
1
2023
371
0.150
Why?
Calcium
1
2026
1191
0.150
Why?
Synaptic Transmission
2
2014
292
0.150
Why?
Rats
4
2021
5585
0.150
Why?
Behavior, Addictive
1
2020
88
0.150
Why?
Genetic Markers
1
2020
338
0.150
Why?
Amygdala
2
2011
200
0.140
Why?
Memory, Short-Term
2
2014
269
0.140
Why?
Electrocorticography
1
2018
20
0.130
Why?
Conditioning, Classical
2
2017
119
0.130
Why?
Artificial Intelligence
1
2022
381
0.130
Why?
Brain Waves
1
2018
45
0.130
Why?
Models, Biological
3
2009
1764
0.130
Why?
Polyribosomes
1
2017
22
0.130
Why?
Models, Animal
2
2017
392
0.120
Why?
Neurofibrillary Tangles
1
2016
13
0.120
Why?
Microscopy, Electron, Transmission
1
2017
156
0.120
Why?
Association Learning
1
2017
70
0.120
Why?
Cell Differentiation
1
2024
2050
0.120
Why?
CA1 Region, Hippocampal
2
2014
50
0.120
Why?
Humans
20
2026
145763
0.120
Why?
Transcription Factors
2
2022
1736
0.120
Why?
Dynamins
1
2015
36
0.110
Why?
Sex Characteristics
1
2020
789
0.110
Why?
Haloperidol
2
2014
32
0.110
Why?
Antipsychotic Agents
2
2014
211
0.110
Why?
Th17 Cells
1
2016
102
0.110
Why?
Maternal-Fetal Exchange
1
2016
170
0.110
Why?
Alcoholism
1
2021
826
0.110
Why?
Electric Stimulation
3
2014
277
0.100
Why?
Social Behavior
1
2017
284
0.100
Why?
Neuroimaging
1
2017
300
0.100
Why?
Cell Count
2
2013
319
0.100
Why?
Antibodies
1
2016
397
0.100
Why?
Pyridines
3
2013
609
0.100
Why?
GABA-A Receptor Agonists
1
2013
17
0.100
Why?
Excitatory Postsynaptic Potentials
2
2011
119
0.100
Why?
Smoking
1
2020
1477
0.100
Why?
Sterols
1
2012
20
0.090
Why?
Nitro Compounds
1
2012
8
0.090
Why?
gamma-Aminobutyric Acid
1
2014
194
0.090
Why?
Brain-Derived Neurotrophic Factor
1
2013
154
0.090
Why?
Multiprotein Complexes
1
2014
172
0.090
Why?
Image Processing, Computer-Assisted
1
2017
782
0.090
Why?
Gene Deletion
1
2013
392
0.090
Why?
Photoperiod
1
2012
55
0.090
Why?
Reaction Time
1
2013
434
0.090
Why?
Ribosomal Protein S6
1
2011
18
0.090
Why?
Dopamine and cAMP-Regulated Phosphoprotein 32
1
2011
9
0.090
Why?
Dopamine
1
2014
295
0.090
Why?
Motor Skills
1
2012
104
0.090
Why?
Amyloid beta-Peptides
2
2011
245
0.090
Why?
Sirolimus
2
2011
282
0.090
Why?
Primary Cell Culture
1
2012
172
0.080
Why?
Ribosomal Protein S6 Kinases, 70-kDa
2
2008
36
0.080
Why?
Oxidants
1
2011
99
0.080
Why?
Cyclic AMP-Dependent Protein Kinases
1
2011
125
0.080
Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 2
2
2014
196
0.080
Why?
Genotype
2
2014
1857
0.080
Why?
Gene Expression Profiling
1
2017
1777
0.080
Why?
Superoxides
1
2011
198
0.080
Why?
Prenatal Exposure Delayed Effects
1
2016
655
0.070
Why?
Enzyme Inhibitors
2
2011
821
0.070
Why?
Oxidative Stress
1
2015
1359
0.070
Why?
Exploratory Behavior
1
2008
85
0.070
Why?
Peptide Elongation Factor 1
1
2008
10
0.070
Why?
Ribosomal Protein S6 Kinases
1
2008
26
0.070
Why?
Membrane Proteins
1
2014
1166
0.070
Why?
Dose-Response Relationship, Radiation
1
2007
141
0.070
Why?
Activating Transcription Factor 4
1
2007
22
0.060
Why?
Eukaryotic Initiation Factor-2
1
2007
32
0.060
Why?
In Situ Hybridization
1
2007
318
0.060
Why?
Space Perception
1
2008
82
0.060
Why?
Pregnancy
2
2017
7215
0.060
Why?
Eukaryotic Initiation Factors
2
2021
12
0.060
Why?
Granulomatous Disease, Chronic
1
2006
49
0.060
Why?
Neuromuscular Junction
2
2003
65
0.060
Why?
Sex Factors
1
2012
2110
0.060
Why?
Pair Bond
1
2026
20
0.060
Why?
Larva
2
2003
240
0.060
Why?
Infant, Newborn
1
2017
6464
0.060
Why?
Purkinje Cells
1
2026
65
0.050
Why?
Mitogen-Activated Protein Kinases
2
2003
288
0.050
Why?
Cohort Studies
1
2015
6032
0.050
Why?
Protein Binding
1
2011
2240
0.050
Why?
Sleep, REM
1
2024
44
0.050
Why?
Protein Domains
1
2026
311
0.050
Why?
Electrodes
1
2024
111
0.050
Why?
Drosophila
1
2025
166
0.050
Why?
Carrier Proteins
2
2010
729
0.050
Why?
Time Factors
2
2012
7133
0.050
Why?
N-Ethylmaleimide-Sensitive Proteins
1
2003
5
0.050
Why?
Calcium-Transporting ATPases
1
2003
33
0.050
Why?
Sarcoplasmic Reticulum Calcium-Transporting ATPases
1
2003
32
0.050
Why?
CCAAT-Enhancer-Binding Proteins
1
2003
37
0.050
Why?
Learning
1
2008
444
0.050
Why?
Body Temperature
1
2024
227
0.050
Why?
Cell Adhesion Molecules, Neuronal
1
2003
42
0.050
Why?
Active Transport, Cell Nucleus
1
2003
117
0.050
Why?
Mitogen-Activated Protein Kinase Kinases
1
2003
126
0.050
Why?
Mice, Inbred Strains
1
2023
396
0.050
Why?
Blood-Brain Barrier
1
2024
160
0.050
Why?
Paralysis
1
2003
69
0.050
Why?
Methoxyhydroxyphenylglycol
2
2014
13
0.050
Why?
Action Potentials
1
2025
502
0.050
Why?
Species Specificity
1
2023
546
0.050
Why?
Transcription Factor AP-1
1
2002
79
0.040
Why?
Psychopathology
1
2021
54
0.040
Why?
Drosophila Proteins
1
2003
214
0.040
Why?
Adult
2
2017
40872
0.040
Why?
Central Nervous System
1
2003
282
0.040
Why?
Lipopolysaccharides
1
2024
858
0.040
Why?
Temperature
1
2003
633
0.040
Why?
Bombyx
1
2000
6
0.040
Why?
Apolipoproteins
1
2000
38
0.040
Why?
Ultrasonography
1
2003
788
0.040
Why?
NADPH Oxidase 2
2
2011
32
0.040
Why?
Seizures
1
2003
485
0.040
Why?
Child
2
2025
22739
0.040
Why?
Age of Onset
1
2020
557
0.030
Why?
NADPH Oxidases
2
2011
122
0.030
Why?
Prepulse Inhibition
1
2017
12
0.030
Why?
Gene Expression Regulation, Developmental
1
2002
910
0.030
Why?
Receptors, Adrenergic, beta-2
1
2017
36
0.030
Why?
Phosphatidylinositol 3-Kinases
2
2010
383
0.030
Why?
Child, Preschool
1
2012
11868
0.030
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2017
94
0.030
Why?
Reflex, Startle
1
2017
75
0.030
Why?
Nuclear Receptor Subfamily 1, Group F, Member 3
1
2016
14
0.030
Why?
Membrane Glycoproteins
2
2011
499
0.030
Why?
Fluorescent Antibody Technique
1
2017
365
0.030
Why?
Antibodies, Blocking
1
2016
37
0.030
Why?
Receptors, Retinoic Acid
1
2016
44
0.030
Why?
Behavioral Symptoms
1
2016
41
0.030
Why?
CRISPR-Cas Systems
1
2017
166
0.030
Why?
Young Adult
1
2012
14251
0.030
Why?
Tobacco Use Disorder
1
2017
217
0.030
Why?
Electrical Synapses
1
2014
6
0.030
Why?
Alcohol Drinking
1
2021
843
0.030
Why?
Biophysical Phenomena
1
2014
67
0.030
Why?
Mechanistic Target of Rapamycin Complex 1
1
2014
138
0.020
Why?
Rotarod Performance Test
1
2012
15
0.020
Why?
Microtubule-Associated Proteins
1
2014
194
0.020
Why?
Post-Synaptic Density
1
2012
12
0.020
Why?
Cyclic GMP
1
2012
90
0.020
Why?
Schizophrenia
1
2017
464
0.020
Why?
Adolescent
1
2012
22573
0.020
Why?
Aged
1
2012
26215
0.020
Why?
Gene Knock-In Techniques
1
2011
61
0.020
Why?
Emetine
1
2011
7
0.020
Why?
Onium Compounds
1
2011
8
0.020
Why?
Bicuculline
1
2011
18
0.020
Why?
GABA-A Receptor Antagonists
1
2011
19
0.020
Why?
rap GTP-Binding Proteins
1
2011
9
0.020
Why?
Ubiquinone
1
2011
35
0.020
Why?
Electrophysiological Phenomena
1
2011
59
0.020
Why?
Biphenyl Compounds
1
2011
67
0.020
Why?
Excitatory Amino Acid Antagonists
1
2011
108
0.020
Why?
Isoproterenol
1
2011
96
0.020
Why?
Adrenergic beta-Agonists
1
2011
92
0.020
Why?
Biophysics
1
2011
75
0.020
Why?
Flavonoids
1
2011
85
0.020
Why?
Organophosphorus Compounds
1
2011
84
0.020
Why?
Eukaryotic Initiation Factor-4A
1
2010
5
0.020
Why?
Patch-Clamp Techniques
1
2011
289
0.020
Why?
Oncogene Protein v-akt
1
2010
24
0.020
Why?
Colorado
1
2020
4556
0.020
Why?
Enzyme Activation
1
2011
762
0.020
Why?
Immunoprecipitation
1
2010
149
0.020
Why?
Middle Aged
1
2012
36302
0.020
Why?
Serine
1
2010
143
0.020
Why?
Superoxide Dismutase
1
2011
308
0.020
Why?
RNA 5' Terminal Oligopyrimidine Sequence
1
2008
1
0.020
Why?
Reactive Oxygen Species
1
2011
611
0.020
Why?
Phosphoproteins
1
2010
337
0.020
Why?
Antioxidants
1
2011
550
0.020
Why?
Autistic Disorder
1
2010
219
0.020
Why?
Extracellular Signal-Regulated MAP Kinases
1
2008
174
0.020
Why?
Dose-Response Relationship, Drug
1
2011
2028
0.020
Why?
Peptide Fragments
1
2010
696
0.020
Why?
Immunosuppressive Agents
1
2011
838
0.010
Why?
Conditioning, Operant
1
2006
94
0.010
Why?
Cell Cycle Proteins
1
2010
630
0.010
Why?
Cognition Disorders
1
2010
544
0.010
Why?
Taste
1
2008
238
0.010
Why?
Receptors, N-Methyl-D-Aspartate
1
2006
229
0.010
Why?
Proto-Oncogene Proteins c-jun
1
2002
54
0.010
Why?
Dimerization
1
2002
189
0.010
Why?
JNK Mitogen-Activated Protein Kinases
1
2002
153
0.010
Why?
Electrophysiology
1
2002
218
0.010
Why?
Cyclic AMP
1
2002
208
0.010
Why?
Proto-Oncogene Proteins c-fos
1
2002
196
0.010
Why?
DNA, Complementary
1
2000
273
0.010
Why?
Promoter Regions, Genetic
1
2002
1247
0.010
Why?
Amino Acid Sequence
1
2000
2131
0.010
Why?
Molecular Sequence Data
1
2000
2883
0.010
Why?
Hoeffer's Networks
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Physical Neighbors Expand Description
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