 Th17 Cells
"Th17 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of helper-effector T-lymphocytes which synthesize and secrete INTERLEUKINS IL-17; IL-17F; and IL-22. These cytokines are involved in host defenses and tissue inflammation in autoimmune diseases.
| Descriptor ID |
D058504
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| MeSH Number(s) |
A11.118.637.555.567.550.500.400.915 A11.118.637.555.567.569.200.400.915 A11.118.637.555.567.569.500.400.915 A15.145.229.637.555.567.550.500.400.770 A15.145.229.637.555.567.569.200.400.770 A15.145.229.637.555.567.569.500.400.770 A15.382.490.555.567.550.500.400.915 A15.382.490.555.567.569.200.400.915 A15.382.490.555.567.569.500.400.915
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| Concept/Terms |
Th17 Cells- Th17 Cells
- Cell, Th17
- Cells, Th17
- Th17 Cell
- TH-17 Cells
- Cell, TH-17
- Cells, TH-17
- TH 17 Cells
- TH-17 Cell
- T Helper 17 Cells
- Type 17 Helper T Cells
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Below are MeSH descriptors whose meaning is more general than "Th17 Cells".
- Anatomy [A]
- Cells [A11]
- Blood Cells [A11.118]
- Leukocytes [A11.118.637]
- Leukocytes, Mononuclear [A11.118.637.555]
- Lymphocytes [A11.118.637.555.567]
- Lymphocyte Subsets [A11.118.637.555.567.550]
- T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
- Th17 Cells [A11.118.637.555.567.550.500.400.915]
- T-Lymphocytes [A11.118.637.555.567.569]
- CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
- Th17 Cells [A11.118.637.555.567.569.200.400.915]
- T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
- Th17 Cells [A11.118.637.555.567.569.500.400.915]
- Hemic and Immune Systems [A15]
- Blood [A15.145]
- Blood Cells [A15.145.229]
- Leukocytes [A15.145.229.637]
- Leukocytes, Mononuclear [A15.145.229.637.555]
- Lymphocytes [A15.145.229.637.555.567]
- Lymphocyte Subsets [A15.145.229.637.555.567.550]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
- Th17 Cells [A15.145.229.637.555.567.550.500.400.770]
- T-Lymphocytes [A15.145.229.637.555.567.569]
- CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
- Th17 Cells [A15.145.229.637.555.567.569.200.400.770]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
- Th17 Cells [A15.145.229.637.555.567.569.500.400.770]
- Immune System [A15.382]
- Leukocytes [A15.382.490]
- Leukocytes, Mononuclear [A15.382.490.555]
- Lymphocytes [A15.382.490.555.567]
- Lymphocyte Subsets [A15.382.490.555.567.550]
- T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
- Th17 Cells [A15.382.490.555.567.550.500.400.915]
- T-Lymphocytes [A15.382.490.555.567.569]
- CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
- Th17 Cells [A15.382.490.555.567.569.200.400.915]
- T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
- Th17 Cells [A15.382.490.555.567.569.500.400.915]
Below are MeSH descriptors whose meaning is more specific than "Th17 Cells".
This graph shows the total number of publications written about "Th17 Cells" by people in this website by year, and whether "Th17 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2011 | 5 | 0 | 5 | | 2012 | 2 | 4 | 6 | | 2013 | 0 | 3 | 3 | | 2014 | 7 | 0 | 7 | | 2015 | 2 | 2 | 4 | | 2016 | 4 | 3 | 7 | | 2017 | 3 | 1 | 4 | | 2018 | 3 | 0 | 3 | | 2019 | 3 | 3 | 6 | | 2020 | 5 | 2 | 7 | | 2021 | 0 | 5 | 5 | | 2022 | 1 | 3 | 4 | | 2023 | 0 | 2 | 2 | | 2024 | 1 | 2 | 3 | | 2025 | 3 | 1 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Th17 Cells" by people in Profiles.
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Yamada-Hara M, Amaya L, Wang Z, Byun JW, Takahashi N, Sharma S, Chang H, Tanaka A, Zeng L, Malakoutikhah Z, Ganguly S, Vu MC, Levin M, Schwartz D, Heath J, Herdman S, Corr M, Raz E, Bertin S. ROR?t Inhibition Reduces Protumor Inflammation and Decreases Tumor Growth in Experimental Models of Lung Cancer. Cancer Immunol Res. 2025 Sep 02; 13(9):1418-1434.
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Loh L, Orlicky DJ, Spengler A, Domenico J, Klarquist J, Levens C, Celli S, Kofonow JM, Robertson CE, Lantz O, Legoux F, Frank DN, Matsuda J, Norman PJ, Kuhn KA, Onyiah J, Gapin L. MAIT cells exacerbate colonic inflammation in a genetically diverse murine model of spontaneous colitis. Mucosal Immunol. 2025 Aug; 18(4):958-972.
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Molina PA, Edell CJ, Dunaway LS, Kellum CE, Muir RQ, Jennings MS, Colson JC, De Miguel C, Rhoads MK, Buzzelli AA, Harrington LE, Meza-Perez S, Randall TD, Botta D, Müller DN, Pollock DM, Maynard CL, Pollock JS. Aryl Hydrocarbon Receptor Activation Promotes Effector CD4+ T Cell Homeostasis and Restrains Salt-Sensitive Hypertension. Function (Oxf). 2025 Mar 24; 6(2).
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Inamo J, Keegan J, Griffith A, Ghosh T, Horisberger A, Howard K, Pulford JF, Murzin E, Hancock B, Dominguez ST, Gurra MG, Gurajala S, Jonsson AH, Seifert JA, Feser ML, Norris JM, Cao Y, Apruzzese W, Bridges SL, Bykerk VP, Goodman S, Donlin LT, Firestein GS, Bathon JM, Hughes LB, Filer A, Pitzalis C, Anolik JH, Moreland L, Hacohen N, Guthridge JM, James JA, Cuda CM, Perlman H, Brenner MB, Raychaudhuri S, Sparks JA, Holers VM, Deane KD, Lederer J, Rao DA, Zhang F. Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis. J Clin Invest. 2025 Mar 17; 135(6).
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Holers VM, Demoruelle KM, Buckner JH, James EA, Firestein GS, Robinson WH, Steere AC, Zhang F, Norris JM, Kuhn KA, Deane KD. Distinct mucosal endotypes as initiators and drivers of rheumatoid arthritis. Nat Rev Rheumatol. 2024 Oct; 20(10):601-613.
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Rosenzweig HL, Vance EE, Asare-Konadu K, Koney KV, Lee EJ, Deodhar AA, Sen R, Caplan L, Napier RJ. Card9/neutrophil signalling axis promotes IL-17A-mediated ankylosing spondylitis. Ann Rheum Dis. 2024 Jan 11; 83(2):214-222.
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Danielson SM, Kuhn KA. IL-10mpting TH17 cell fate in the gut. Sci Immunol. 2024 01 05; 9(91):eadn7536.
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Erdem S, Haskologlu S, Haliloglu Y, Celikzencir H, Arik E, Keskin O, Eltan SB, Yucel E, Canatan H, Avcilar H, Yilmaz E, Ozcan A, Unal E, Karakukcu M, Celiksoy MH, Kilic SS, Demir A, Genel F, Gulez N, Koker MY, Ozen AO, Baris S, Metin A, Guner SN, Reisli I, Keles S, Dogu EF, Ikinciogullari KA, Eken A. Defective Treg generation and increased type 3 immune response in leukocyte adhesion deficiency 1. Clin Immunol. 2023 08; 253:109691.
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Motz KM, Lina IA, Samad I, Murphy MK, Duvvuri M, Davis RJ, Gelbard A, Chung L, Chan-Li Y, Collins S, Powell JD, Elisseeff JH, Horton MR, Hillel AT. Sirolimus-eluting airway stent reduces profibrotic Th17 cells and inhibits laryngotracheal stenosis. JCI Insight. 2023 06 08; 8(11).
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Baixauli F, Piletic K, Puleston DJ, Villa M, Field CS, Flachsmann LJ, Quintana A, Rana N, Edwards-Hicks J, Matsushita M, Stanczak MA, Grzes KM, Kabat AM, Fabri M, Caputa G, Kelly B, Corrado M, Musa Y, Duda KJ, Mittler G, O'Sullivan D, Sesaki H, Jenuwein T, Buescher JM, Pearce EJ, Sanin DE, Pearce EL. An LKB1-mitochondria axis controls TH17 effector function. Nature. 2022 10; 610(7932):555-561.
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