 Nuclear Receptor Subfamily 1, Group F, Member 3
"Nuclear Receptor Subfamily 1, Group F, Member 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An orphan nuclear receptor found in the THYMUS where it plays a role in regulating the development and maturation of thymocytes. An isoform of this protein, referred to as RORgammaT, is produced by an alternatively transcribed mRNA.
| Descriptor ID |
D057132
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| MeSH Number(s) |
D12.776.260.643.182 D12.776.826.209.182
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| Concept/Terms |
Nuclear Receptor Subfamily 1, Group F, Member 3- Nuclear Receptor Subfamily 1, Group F, Member 3
- Nuclear Receptor RZR-gamma
- Nuclear Receptor RZR gamma
- Receptor RZR-gamma, Nuclear
- ROR-gamma
- Orphan Nuclear Receptor ROR-gamma
- Orphan Nuclear Receptor ROR gamma
- RAR-related Orphan Receptor C
- RAR related Orphan Receptor C
- ROR-C Receptors
- ROR C Receptors
- Nuclear Receptor NR1F3
- Receptor NR1F3, Nuclear
- Orphan Nuclear Receptor NR1F3
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 1, Group F, Member 3".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 1, Group F, Member 3".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 1, Group F, Member 3" by people in this website by year, and whether "Nuclear Receptor Subfamily 1, Group F, Member 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2021 | 1 | 1 | 2 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Subfamily 1, Group F, Member 3" by people in Profiles.
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Kathania M, Kumar R, Lenou ET, Basrur V, Theiss AL, Chernoff J, Venuprasad K. Pak2-mediated phosphorylation promotes ROR?t ubiquitination and inhibits colonic inflammation. Cell Rep. 2022 09 13; 40(11):111345.
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Kumar R, Theiss AL, Venuprasad K. ROR?t protein modifications and IL-17-mediated inflammation. Trends Immunol. 2021 11; 42(11):1037-1050.
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Kumar R, Singh AK, Starokadomskyy P, Luo W, Theiss AL, Burstein E, Venuprasad K. Cutting Edge: Hypoxia-Induced Ubc9 Promoter Hypermethylation Regulates IL-17 Expression in Ulcerative Colitis. J Immunol. 2021 03 01; 206(5):936-940.
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Betts CB, Pennock ND, Caruso BP, Ruffell B, Borges VF, Schedin P. Mucosal Immunity in the Female Murine Mammary Gland. J Immunol. 2018 07 15; 201(2):734-746.
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K?stle M, Bartel S, Geillinger-K?stle K, Irmler M, Beckers J, Ryffel B, Eickelberg O, Krauss-Etschmann S. microRNA cluster 106a~363 is involved in T helper 17 cell differentiation. Immunology. 2017 11; 152(3):402-413.
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Choi GB, Yim YS, Wong H, Kim S, Kim H, Kim SV, Hoeffer CA, Littman DR, Huh JR. The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science. 2016 Feb 26; 351(6276):933-9.
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Song P, Chou YK, Zhang X, Meza-Romero R, Yomogida K, Benedek G, Chu CQ. CD4 aptamer-ROR?t shRNA chimera inhibits IL-17 synthesis by human CD4(+) T cells. Biochem Biophys Res Commun. 2014 Oct 03; 452(4):1040-5.
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Malhotra N, Narayan K, Cho OH, Sylvia KE, Yin C, Melichar H, Rashighi M, Lefebvre V, Harris JE, Berg LJ, Kang J. A network of high-mobility group box transcription factors programs innate interleukin-17 production. Immunity. 2013 Apr 18; 38(4):681-93.
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Ahn YO, Blazar BR, Miller JS, Verneris MR. Lineage relationships of human interleukin-22-producing CD56+ ROR?t+ innate lymphoid cells and conventional natural killer cells. Blood. 2013 Mar 21; 121(12):2234-43.
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Purwar R, Schlapbach C, Xiao S, Kang HS, Elyaman W, Jiang X, Jetten AM, Khoury SJ, Fuhlbrigge RC, Kuchroo VK, Clark RA, Kupper TS. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat Med. 2012 Aug; 18(8):1248-53.
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