 Epistasis, Genetic
"Epistasis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
| Descriptor ID |
D004843
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| MeSH Number(s) |
G05.308.207
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| Concept/Terms |
Epistasis, Genetic- Epistasis, Genetic
- Epistases, Genetic
- Gene-Gene Interactions, Epistatic
- Gene Gene Interactions, Epistatic
- Gene-Gene Interaction, Epistatic
- Epistatic Gene-Gene Interaction
- Epistatic Gene-Gene Interactions
- Gene Gene Interaction, Epistatic
- Interaction, Epistatic Gene-Gene
- Interactions, Epistatic Gene-Gene
- Non-Allelic Gene Interactions
- Gene Interaction, Non-Allelic
- Gene Interactions, Non-Allelic
- Interaction, Non-Allelic Gene
- Interactions, Non-Allelic Gene
- Non Allelic Gene Interactions
- Non-Allelic Gene Interaction
- Genetic Epistasis
- Genetic Epistases
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Below are MeSH descriptors whose meaning is more general than "Epistasis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epistasis, Genetic".
This graph shows the total number of publications written about "Epistasis, Genetic" by people in this website by year, and whether "Epistasis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 1 | 2 | 3 | | 2008 | 2 | 1 | 3 | | 2009 | 0 | 3 | 3 | | 2010 | 5 | 2 | 7 | | 2011 | 2 | 1 | 3 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 2 | 2 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 3 | 4 | | 2016 | 1 | 3 | 4 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 3 | 3 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 1 | 2 | | 2021 | 1 | 3 | 4 | | 2023 | 2 | 1 | 3 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Epistasis, Genetic" by people in Profiles.
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Nebenfuehr B, Sanford L, Taylor ER, Ball K, Woods-Killam CE, Ghasemi HI, Proctor B, Ortega R, Sempeck C, Dowell RD, Arnoult N. Uncovering genetic interactions in the DNA repair network in response to endogenous damage and ionizing radiation. Cell Rep. 2026 Jan 27; 45(1):116850.
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Pividori M, Lu S, Li B, Su C, Johnson ME, Wei WQ, Feng Q, Namjou B, Kiryluk K, Kullo IJ, Luo Y, Sullivan BD, Voight BF, Skarke C, Ritchie MD, Grant SFA, Greene CS. Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms. Nat Commun. 2023 09 09; 14(1):5562.
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Evans LM, Arehart CH, Grotzinger AD, Mize TJ, Brasher MS, Stitzel JA, Ehringer MA, Hoeffer CA. Transcriptome-wide gene-gene interaction associations elucidate pathways and functional enrichment of complex traits. PLoS Genet. 2023 05; 19(5):e1010693.
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Liu R, Hirn M, Krishnan A. Accurately modeling biased random walks on weighted networks using node2vec. Bioinformatics. 2023 01 01; 39(1).
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Bautista DE, Carr JF, Mitchell AM. Suppressor Mutants: History and Today's Applications. EcoSal Plus. 2021 12 15; 9(2):eESP00372020.
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Rosser N, Edelman NB, Queste LM, Nelson M, Seixas F, Dasmahapatra KK, Mallet J. Complex basis of hybrid female sterility and Haldane's rule in Heliconius butterflies: Z-linkage and epistasis. Mol Ecol. 2022 02; 31(3):959-977.
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Eccleston RC, Pollock DD, Goldstein RA. Selection for cooperativity causes epistasis predominately between native contacts and enables epistasis-based structure reconstruction. Proc Natl Acad Sci U S A. 2021 04 20; 118(16).
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Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Desai I, Karthikeyan S, Gould DJ, Yennawar S, Weiner AT, Pounraja VK, Krishnan A, Rolls MM, Lowery LA, Girirajan S. Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. PLoS Genet. 2021 04; 17(4):e1009112.
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Semenov GA, Linck E, Enbody ED, Harris RB, Khaydarov DR, Alström P, Andersson L, Taylor SA. Asymmetric introgression reveals the genetic architecture of a plumage trait. Nat Commun. 2021 02 15; 12(1):1019.
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Moreno DF, Acar M. Chromatin regulatory genes differentially interact in networks to facilitate distinct GAL1 activity and noise profiles. Curr Genet. 2021 Apr; 67(2):267-281.
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