RNA 5' Terminal Oligopyrimidine Sequence
"RNA 5' Terminal Oligopyrimidine Sequence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.
| Descriptor ID |
D038641
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| MeSH Number(s) |
G02.111.570.080.689.687.275 G05.360.080.689.687.275 G05.360.340.024.340.137.785
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "RNA 5' Terminal Oligopyrimidine Sequence".
Below are MeSH descriptors whose meaning is more specific than "RNA 5' Terminal Oligopyrimidine Sequence".
This graph shows the total number of publications written about "RNA 5' Terminal Oligopyrimidine Sequence" by people in this website by year, and whether "RNA 5' Terminal Oligopyrimidine Sequence" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA 5' Terminal Oligopyrimidine Sequence" by people in Profiles.
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Antion MD, Hou L, Wong H, Hoeffer CA, Klann E. mGluR-dependent long-term depression is associated with increased phosphorylation of S6 and synthesis of elongation factor 1A but remains expressed in S6K-deficient mice. Mol Cell Biol. 2008 May; 28(9):2996-3007.