 Long-Term Potentiation
"Long-Term Potentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A persistent increase in synaptic efficacy, usually induced by appropriate activation of the same synapses. The phenomenological properties of long-term potentiation suggest that it may be a cellular mechanism of learning and memory.
| Descriptor ID |
D017774
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| MeSH Number(s) |
G11.561.638.350
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| Concept/Terms |
Long-Term Potentiation- Long-Term Potentiation
- Long Term Potentiation
- Long-Term Potentiations
- Potentiation, Long-Term
- Potentiations, Long-Term
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Below are MeSH descriptors whose meaning is more general than "Long-Term Potentiation".
Below are MeSH descriptors whose meaning is more specific than "Long-Term Potentiation".
This graph shows the total number of publications written about "Long-Term Potentiation" by people in this website by year, and whether "Long-Term Potentiation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 | | 1998 | 2 | 1 | 3 | | 1999 | 2 | 2 | 4 | | 2001 | 0 | 2 | 2 | | 2002 | 3 | 2 | 5 | | 2004 | 2 | 0 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 2 | 4 | | 2007 | 2 | 2 | 4 | | 2008 | 2 | 1 | 3 | | 2009 | 1 | 0 | 1 | | 2010 | 3 | 2 | 5 | | 2011 | 4 | 3 | 7 | | 2012 | 2 | 5 | 7 | | 2013 | 1 | 1 | 2 | | 2014 | 3 | 4 | 7 | | 2015 | 2 | 1 | 3 | | 2016 | 6 | 1 | 7 | | 2017 | 3 | 6 | 9 | | 2018 | 4 | 2 | 6 | | 2019 | 1 | 3 | 4 | | 2020 | 1 | 1 | 2 | | 2021 | 2 | 0 | 2 | | 2022 | 1 | 1 | 2 | | 2023 | 2 | 1 | 3 | | 2024 | 4 | 3 | 7 | | 2025 | 4 | 3 | 7 | | 2026 | 1 | 4 | 5 |
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Below are the most recent publications written about "Long-Term Potentiation" by people in Profiles.
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Gong S, Adler J, Zhu Y, Szeto C, Lin L, Rauffenbart C, Torres-Herraez A, Asher WB, Javitch JA, Ford CP. Dopamine D2 receptors bypass canonical signaling to directly tune NMDA receptor function and aversive learning. Sci Adv. 2026 Jul 24; 12(30):eaee6579.
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Tsokas P, Hsieh C, Grau-Perales A, Tcherepanov A, Kwok L, Rodriguez-Valencia L, Cano DA, Allen K, Smith HJ, Kubayeva S, Wei BJ, Sabzanov S, Flores-Obando R, Ghosh S, Bergold PJ, Rudy J, Cottrell J, Fenton A, Sacktor TC. PKM?-PKC?/? double-knockout demonstrates atypical PKC is crucial for the persistence of hippocampal LTP and spatial memory. Elife. 2026 Jul 22; 15.
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Rudy JW. Oligomer logic of memory molecules. Mol Brain. 2026 May 08; 19(1).
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Larsen ME, Barker CM, Vargas RS, Coultrap SJ, Bayer KU. The CaMKII D135N mutation blocks kinase activity and reduces GluN2B binding. Mol Pharmacol. 2026 May-Jun; 108(5-6):100127.
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Henry JE, Fineberg AA, McVey TB, Tiemeier EL, Orfila JE, Herson PS, Dietz RM. Delayed administration of type II ampakines enhance synaptic plasticity and cognitive recovery in juvenile global cerebral ischemia. J Cereb Blood Flow Metab. 2026 Jun; 46(6):1681-1692.
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Fineberg A, McVey T, Henry J, Tiemeyer E, Orfila JE, Dietz RM. Delayed Fluoxetine Administration Restores Hippocampal Function in a Juvenile Global Cerebral Ischemia Mouse Model in a Sex-Specific Manner. Neural Plast. 2025; 2025:8841616.
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Thacker JS, Ralph LT, Koek L, Abbasian A, Bettio LB, Smith AE, Georgiou J, Christie BR, Collingridge GL. Synergistic actions of corticosterone and BDNF on rat hippocampal LTP. Mol Brain. 2025 May 12; 18(1):42.
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Vigil JJ, Tiemeier E, Orfila JE, Chalmers NE, Chang VN, Mitchell D, Veitch I, Falk M, Dietz RM, Herson PS, Quillinan N. Endogenous Recovery of Hippocampal Function Following Global Cerebral Ischemia in Juvenile Female Mice Is Influenced by Neuroinflammation and Circulating Sex Hormones. Neural Plast. 2025; 2025:6103242.
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Larsen ME, Rumian NL, Quillinan N, Bayer KU. CaMKII mechanisms that promote pathological LTP impairments. Curr Opin Neurobiol. 2025 Jun; 92:102961.
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Brown CN, Chao FY, Quang D, Rumian NL, Kleinjan MS, Coultrap SJ, Bayer KU. Aß impairs the LTP-related movement of endogenous CaMKII but not of exogenous GFP-CaMKII. Mol Biol Cell. 2025 May 01; 36(5):ar60.
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